KEGG   ORTHOLOGY: K04466Help
Entry
K04466                      KO                                     

Name
MAP3K14, NIK
Definition
mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
Pathway
ko04010  MAPK signaling pathway
ko04064  NF-kappa B signaling pathway
ko04210  Apoptosis
ko04380  Osteoclast differentiation
ko04625  C-type lectin receptor signaling pathway
ko04660  T cell receptor signaling pathway
ko04668  TNF signaling pathway
ko04672  Intestinal immune network for IgA production
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05166  HTLV-I infection
ko05169  Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
   04064 NF-kappa B signaling pathway
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
   04668 TNF signaling pathway
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
   04660 T cell receptor signaling pathway
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
   04672 Intestinal immune network for IgA production
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
  09158 Development
   04380 Osteoclast differentiation
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
 09160 Human Diseases
  09167 Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
   05166 HTLV-I infection
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
   05169 Epstein-Barr virus infection
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  Other
   K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14
BRITE hierarchy
Other DBs
GO: 0004709
Genes
HSA: 9020(MAP3K14)
PTR: 454750(MAP3K14)
PPS: 100984930(MAP3K14)
GGO: 101147819(MAP3K14)
PON: 100436201(MAP3K14)
NLE: 100600394(MAP3K14)
MCC: 716258(MAP3K14)
MCF: 102145584(MAP3K14)
CSAB: 103243289(MAP3K14)
RRO: 104678377(MAP3K14)
RBB: 108532216(MAP3K14)
CJC: 100401112(MAP3K14)
SBQ: 101044826(MAP3K14)
MMU: 53859(Map3k14)
RNO: 360640(Map3k14)
CGE: 100766459(Map3k14)
NGI: 103738320(Map3k14)
HGL: 101703313(Map3k14)
CCAN: 109691665(Map3k14)
OCU: 100351032(MAP3K14)
TUP: 102500729(MAP3K14)
CFA: 490926(MAP3K14)
AML: 100472260(MAP3K14)
UMR: 103665883(MAP3K14)
ORO: 101363246(MAP3K14)
FCA: 101083468(MAP3K14)
PTG: 102964388(MAP3K14)
AJU: 106988147(MAP3K14)
BTA: 508367(MAP3K14)
BOM: 102268339(MAP3K14)
BIU: 109574056(MAP3K14)
PHD: 102326524(MAP3K14)
CHX: 102189617(MAP3K14)
OAS: 101118799(MAP3K14)
SSC: 100520402(MAP3K14)
CFR: 102504523(MAP3K14)
CDK: 105094405(MAP3K14)
BACU: 103015859(MAP3K14)
LVE: 103082490(MAP3K14)
OOR: 101270119(MAP3K14)
ECB: 100050140(MAP3K14)
EPZ: 103554685(MAP3K14)
EAI: 106836478(MAP3K14)
MYB: 102262247(MAP3K14)
MYD: 102762988(MAP3K14)
HAI: 109395015(MAP3K14)
RSS: 109458539(MAP3K14)
PALE: 102897751(MAP3K14)
LAV: 100661927(MAP3K14)
TMU: 101343418
MDO: 100020668(MAP3K14)
SHR: 100918124(MAP3K14)
OAA: 100085554
GGA: 419964(MAP3K14)
MGP: 100538760(MAP3K14)
CJO: 107325016(MAP3K14)
APLA: 101791236(MAP3K14)
ACYG: 106046936(MAP3K14)
TGU: 100217837(MAP3K14)
GFR: 102038763(MAP3K14)
FAB: 101813386(MAP3K14)
PHI: 102113463(MAP3K14)
PMAJ: 107215307(MAP3K14)
CCW: 104698524(MAP3K14)
FPG: 101919762(MAP3K14)
FCH: 102048630(MAP3K14)
CLV: 102088332(MAP3K14)
EGZ: 104132232(MAP3K14)
AAM: 106495649(MAP3K14)
ASN: 102388858(MAP3K14)
AMJ: 102575720(MAP3K14)
PSS: 102464024(MAP3K14)
CMY: 102939834(MAP3K14)
CPIC: 101932285(MAP3K14)
ACS: 100560190(map3k14)
PVT: 110081369(MAP3K14)
PBI: 103066049(MAP3K14)
GJA: 107125527(MAP3K14)
XLA: 108700848(map3k14.L) 108702551(map3k14.S)
XTR: 100489201(map3k14)
NPR: 108785983(MAP3K14)
DRE: 100004261(map3k14a) 795766
TRU: 101067596(map3k14) 101068369
BPEC: 110168889
LCM: 102351315(MAP3K14)
CIN: 100177364
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9020361
  Authors
Malinin NL, Boldin MP, Kovalenko AV, Wallach D
  Title
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.
  Journal
Nature 385:540-4 (1997)
DOI:10.1038/385540a0
  Sequence
[hsa:9020]
Reference
  Authors
Liao G, Zhang M, Harhaj EW, Sun SC
  Title
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.
  Journal
J Biol Chem 279:26243-50 (2004)
DOI:10.1074/jbc.M403286200
  Sequence
[hsa:9020]

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