KEGG   ORTHOLOGY: K04503Help
Entry
K04503                      KO                                     

Name
CCND1
Definition
G1/S-specific cyclin-D1
Pathway
ko01522  Endocrine resistance
ko04068  FoxO signaling pathway
ko04110  Cell cycle
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04152  AMPK signaling pathway
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04340  Hedgehog signaling pathway
ko04371  Apelin signaling pathway
ko04390  Hippo signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04630  JAK-STAT signaling pathway
ko04917  Prolactin signaling pathway
ko04919  Thyroid hormone signaling pathway
ko04921  Oxytocin signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko04934  Cushing syndrome
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05210  Colorectal cancer
ko05212  Pancreatic cancer
ko05213  Endometrial cancer
ko05214  Glioma
ko05215  Prostate cancer
ko05216  Thyroid cancer
ko05218  Melanoma
ko05219  Bladder cancer
ko05220  Chronic myeloid leukemia
ko05221  Acute myeloid leukemia
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
ko05416  Viral myocarditis
Module
M00692  Cell cycle - G1/S transition
Disease
H00006  Hairy-cell leukemia
H00010  Multiple myeloma
H00016  Oral cancer
H00017  Esophageal cancer
H00031  Breast cancer
H00055  Laryngeal cancer
H00559  von Hippel-Lindau syndrome
H01464  Mantle cell lymphoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04340 Hedgehog signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04390 Hippo signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04371 Apelin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04630 Jak-STAT signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04068 FoxO signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04151 PI3K-Akt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04152 AMPK signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K04503  CCND1; G1/S-specific cyclin-D1
   04115 p53 signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04218 Cellular senescence
    K04503  CCND1; G1/S-specific cyclin-D1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04503  CCND1; G1/S-specific cyclin-D1
   04530 Tight junction
    K04503  CCND1; G1/S-specific cyclin-D1
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04921 Oxytocin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04919 Thyroid hormone signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05206 MicroRNAs in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05205 Proteoglycans in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05203 Viral carcinogenesis
    K04503  CCND1; G1/S-specific cyclin-D1
   05210 Colorectal cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05212 Pancreatic cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05225 Hepatocellular carcinoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05226 Gastric cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05214 Glioma
    K04503  CCND1; G1/S-specific cyclin-D1
   05216 Thyroid cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05221 Acute myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05220 Chronic myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05218 Melanoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05219 Bladder cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05215 Prostate cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05213 Endometrial cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05224 Breast cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05222 Small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05223 Non-small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
  09165 Cardiovascular diseases
   05416 Viral myocarditis
    K04503  CCND1; G1/S-specific cyclin-D1
  09166 Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04503  CCND1; G1/S-specific cyclin-D1
   04934 Cushing syndrome
    K04503  CCND1; G1/S-specific cyclin-D1
  09167 Infectious diseases
   05166 HTLV-I infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05162 Measles
    K04503  CCND1; G1/S-specific cyclin-D1
   05161 Hepatitis B
    K04503  CCND1; G1/S-specific cyclin-D1
   05163 Human cytomegalovirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05165 Human papillomavirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
  09168 Drug resistance
   01522 Endocrine resistance
    K04503  CCND1; G1/S-specific cyclin-D1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00692  Cell cycle - G1/S transition
     K04503  CCND1; G1/S-specific cyclin-D1
BRITE hierarchy
Genes
HSA: 595(CCND1)
PTR: 747442(CCND1)
PPS: 100995605(CCND1)
GGO: 101130447(CCND1)
PON: 100171625(CCND1)
NLE: 100605736(CCND1)
MCC: 574320(CCND1)
MCF: 102135329(CCND1)
CSAB: 103246489(CCND1)
RRO: 104677168(CCND1)
RBB: 108538745(CCND1)
CJC: 100399312 103796419(CCND1)
SBQ: 101047858(CCND1)
MMU: 12443(Ccnd1)
RNO: 58919(Ccnd1)
CGE: 100689063(Ccnd1)
NGI: 103751498(Ccnd1)
HGL: 101712621(Ccnd1)
CCAN: 109696351(Ccnd1)
TUP: 102490651(CCND1)
CFA: 449028(CCND1)
AML: 100469787(CCND1)
UMR: 103671139(CCND1)
ORO: 101371532(CCND1)
FCA: 100037407(CCND1)
PTG: 102959906(CCND1)
AJU: 106971167(CCND1)
BTA: 524530(CCND1)
BOM: 102270546(CCND1)
BIU: 109554439(CCND1)
PHD: 102332867(CCND1)
CHX: 102169650(CCND1)
OAS: 100144763(CCND1)
SSC: 100738589(CCND1)
CFR: 102518309(CCND1)
CDK: 105104393(CCND1)
BACU: 103013404(CCND1)
LVE: 103090612(CCND1)
OOR: 101273294(CCND1)
ECB: 102149114(CCND1)
EPZ: 103542876(CCND1)
EAI: 106844248(CCND1)
MYB: 102263484(CCND1)
MYD: 102759793(CCND1)
HAI: 109389297(CCND1)
RSS: 109460368(CCND1)
PALE: 102885330(CCND1)
LAV: 100669703(CCND1)
TMU: 101359745
MDO: 100013257(CCND1)
SHR: 100917462(CCND1)
OAA: 100075081(CCND1)
GGA: 396341(CCND1)
MGP: 100539759(CCND1)
CJO: 107314428(CCND1)
APLA: 101800639(CCND1)
ACYG: 106044779(CCND1)
TGU: 100231612(CCND1)
GFR: 102042858(CCND1)
FAB: 101807319(CCND1)
PHI: 102099659(CCND1)
PMAJ: 107205992(CCND1)
CCW: 104697629(CCND1)
FPG: 101914937(CCND1)
FCH: 102053036(CCND1)
CLV: 102086245(CCND1)
EGZ: 104124693(CCND1)
AAM: 106498229(CCND1)
ASN: 102378816(CCND1)
AMJ: 102563714(CCND1)
PSS: 102457993(CCND1)
CMY: 102947923(CCND1)
CPIC: 101943958(CCND1)
ACS: 100563772(ccnd1)
PVT: 110073542(CCND1)
PBI: 103066913(CCND1)
GJA: 107121511(CCND1)
XLA: 108697837 379161(ccnd1.S) 379937(ccnd1.L) 447748(ccndx.L)
XTR: 448045(ccnd1)
NPR: 108785450(CCND1) 108793412
DRE: 30222(ccnd1)
CCAR: 109093191(ccnd1)
IPU: 108271119(ccnd1)
AMEX: 103031956(ccnd1)
TRU: 101061278(ccnd1) 101077531
NCC: 104950786(ccnd1) 104967413
MZE: 101467298 101485361(ccnd1)
OLA: 101169672(ccnd1)
XMA: 102233074(ccnd1)
PRET: 103462287(ccnd1)
NFU: 107374449(ccnd1)
CSEM: 103379080 103379853(ccnd1)
BPEC: 110169262(ccnd1) 110174870
ELS: 105017289(ccnd1) 105018279
SFM: 108940463 108941209(ccnd1)
LCM: 102361167(CCND1)
SPU: 373245
FCY: FRACYDRAFT_140762(dsCyc9b)
SPAR: SPRG_00758
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1826542
  Authors
Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM, Arnold A
  Title
A novel cyclin encoded by a bcl1-linked candidate oncogene.
  Journal
Nature 350:512-5 (1991)
DOI:10.1038/350512a0
  Sequence
[hsa:595]

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