KEGG   ORTHOLOGY: K04553Help
Entry
K04553                      KO                                     

Name
UBE2L6, UBCH8
Definition
ubiquitin-conjugating enzyme E2 L6 [EC:2.3.2.23]
Pathway
ko04120  Ubiquitin mediated proteolysis
ko05012  Parkinson disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05012 Parkinson disease
    K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.23  E2 ubiquitin-conjugating enzyme
     K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6
Ubiquitin system [BR:ko04121]
 Ubiquitin-conjugating enzymes (E2)
  Ubiquitin-conjugating enzymes
   K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6
  UBL-conjugating enzymes
   K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6
BRITE hierarchy
Genes
HSA: 9246(UBE2L6)
PTR: 466588(UBE2L6)
PPS: 100967273(UBE2L6)
GGO: 101132478(UBE2L6)
PON: 100461401(UBE2L6)
NLE: 100582316(UBE2L6)
MCC: 705561(UBE2L6)
MCF: 102136629(UBE2L6)
CSAB: 103235390(UBE2L6)
RRO: 104654284(UBE2L6)
RBB: 108514859(UBE2L6)
CJC: 100385742(UBE2L6)
SBQ: 101047085(UBE2L6)
MMU: 56791(Ube2l6)
RNO: 295704(Ube2l6)
CGE: 100756751(Ube2l6)
NGI: 103736634(Ube2l6)
HGL: 101725275(Ube2l6)
CCAN: 109688989(Ube2l6)
OCU: 100349814(UBE2L6)
TUP: 102487625(UBE2L6)
CFA: 475967(UBE2L6)
AML: 100477578(UBE2L6)
UMR: 103666116(UBE2L6)
ORO: 101364334(UBE2L6)
FCA: 101090548(UBE2L6)
PTG: 102971733(UBE2L6)
AJU: 106979559(UBE2L6)
BTA: 509471(UBE2L6)
BOM: 102279716(UBE2L6)
BIU: 109569874(UBE2L6)
PHD: 102338346(UBE2L6)
CHX: 102181617(UBE2L6)
OAS: 101121201(UBE2L6)
SSC: 100514753(UBE2L6)
CFR: 102514746(UBE2L6)
CDK: 105101227(UBE2L6)
BACU: 103005432(UBE2L6)
LVE: 103090749(UBE2L6)
OOR: 101279943(UBE2L6)
ECB: 100066866(UBE2L6)
EPZ: 103558229(UBE2L6)
EAI: 106822570(UBE2L6)
MYB: 102248620(UBE2L6)
MYD: 102759984(UBE2L6)
HAI: 109371660(UBE2L6)
RSS: 109436665(UBE2L6)
PALE: 102885640(UBE2L6)
LAV: 100656917(UBE2L6)
TMU: 101359159
MDO: 100025425(UBE2L6)
SHR: 100929865(UBE2L6)
OAA: 100080625(UBE2L6)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Buchwald M, Pietschmann K, Muller JP, Bohmer FD, Heinzel T, Kramer OH
  Title
Ubiquitin conjugase UBCH8 targets active FMS-like tyrosine kinase 3 for proteasomal degradation.
  Journal
Leukemia 24:1412-21 (2010)
DOI:10.1038/leu.2010.114
  Sequence
[hsa:9246]

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