KEGG   ORTHOLOGY: K04634Help
Entry
K04634                      KO                                     

Name
GNAQ
Definition
guanine nucleotide-binding protein G(q) subunit alpha
Pathway
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04071  Sphingolipid signaling pathway
ko04261  Adrenergic signaling in cardiomyocytes
ko04270  Vascular smooth muscle contraction
ko04371  Apelin signaling pathway
ko04540  Gap junction
ko04611  Platelet activation
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko04745  Phototransduction - fly
ko04750  Inflammatory mediator regulation of TRP channels
ko04911  Insulin secretion
ko04912  GnRH signaling pathway
ko04915  Estrogen signaling pathway
ko04916  Melanogenesis
ko04918  Thyroid hormone synthesis
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04934  Cushing syndrome
ko04961  Endocrine and other factor-regulated calcium reabsorption
ko04970  Salivary secretion
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko05010  Alzheimer disease
ko05016  Huntington disease
ko05142  Chagas disease (American trypanosomiasis)
ko05143  African trypanosomiasis
ko05146  Amoebiasis
ko05163  Human cytomegalovirus infection
ko05200  Pathways in cancer
Disease
H01809  Sturge-Weber syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04371 Apelin signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04020 Calcium signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04071 Sphingolipid signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04022 cGMP - PKG signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09152 Endocrine system
   04911 Insulin secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04922 Glucagon signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04912 GnRH signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04915 Estrogen signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04921 Oxytocin signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04918 Thyroid hormone synthesis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04928 Parathyroid hormone synthesis, secretion and action
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04916 Melanogenesis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04924 Renin secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04925 Aldosterone synthesis and secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04927 Cortisol synthesis and secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04270 Vascular smooth muscle contraction
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09154 Digestive system
   04970 Salivary secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04971 Gastric acid secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04972 Pancreatic secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09156 Nervous system
   04724 Glutamatergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04725 Cholinergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04728 Dopaminergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04726 Serotonergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04720 Long-term potentiation
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04730 Long-term depression
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04723 Retrograde endocannabinoid signaling
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09157 Sensory system
   04745 Phototransduction - fly
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04750 Inflammatory mediator regulation of TRP channels
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   05016 Huntington disease
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09166 Endocrine and metabolic diseases
   04934 Cushing syndrome
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  09167 Infectious diseases
   05163 Human cytomegalovirus infection
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   05146 Amoebiasis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   05142 Chagas disease (American trypanosomiasis)
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   05143 African trypanosomiasis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04031 GTP-binding proteins
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 3 (Gq/11) [OT]
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
BRITE hierarchy
Genes
HSA: 2776(GNAQ)
PTR: 472962(GNAQ)
PPS: 100986730(GNAQ)
GGO: 101149651(GNAQ)
PON: 100458686(GNAQ)
NLE: 100594473(GNAQ)
MCC: 705680(GNAQ)
MCF: 102130397(GNAQ)
CSAB: 103219624(GNAQ)
RRO: 104663314(GNAQ) 104663322
RBB: 108542641(GNAQ)
CJC: 100403006(GNAQ)
SBQ: 101051855(GNAQ)
MMU: 14682(Gnaq)
RNO: 81666(Gnaq)
CGE: 100689066(Gnaq)
NGI: 103734421(Gnaq)
HGL: 101715420(Gnaq)
OCU: 100340719(GNAQ)
TUP: 102468263(GNAQ)
CFA: 403928(GNAQ)
AML: 100464853(GNAQ)
UMR: 103663281(GNAQ)
ORO: 101384596(GNAQ)
FCA: 101094708(GNAQ)
PTG: 102954227(GNAQ)
AJU: 106975317(GNAQ)
BTA: 536654(GNAQ)
BOM: 102287414(GNAQ)
BIU: 109562978(GNAQ)
PHD: 102316799(GNAQ)
CHX: 102189950(GNAQ)
OAS: 101112295(GNAQ)
SSC: 654405(GNAQ)
CFR: 102508547(GNAQ)
CDK: 105087414(GNAQ)
BACU: 103018216(GNAQ)
LVE: 103082420(GNAQ)
OOR: 101279781(GNAQ)
ECB: 100063136(GNAQ)
EPZ: 103553450(GNAQ)
EAI: 106825688(GNAQ)
MYB: 102247263(GNAQ)
MYD: 102760847(GNAQ)
HAI: 109385746
RSS: 109449927
PALE: 102877919
LAV: 100656672(GNAQ)
TMU: 101347192
MDO: 100011605(GNAQ)
SHR: 100916183
GGA: 427262(GNAQ)
CJO: 107306232(GNAQ)
APLA: 101790479 101794123(GNAQ)
ACYG: 106045450
TGU: 100230245(GNAQ)
FAB: 101809288(GNAQ)
PHI: 102103304(GNAQ)
PMAJ: 107216294(GNAQ)
CCW: 104691989
FPG: 101912464(GNAQ)
FCH: 102046812(GNAQ)
CLV: 102093509
EGZ: 104124721(GNAQ)
AAM: 106495031
ASN: 102388376(GNAQ)
AMJ: 102565550(GNAQ)
PSS: 102454459(GNAQ)
CMY: 102941281(GNAQ)
CPIC: 101949854(GNAQ)
ACS: 100565556(gnaq)
PVT: 110076012
PBI: 103054358
XLA: 394425(gnaq.L) 399261(gnaq.S)
XTR: 733773(gnaq)
NPR: 108788493
DRE: 445232(gna15.1) 445297(gna14) 562625(gna15.4) 563953(gna11a) 570108(gnaq)
LCM: 102352409(GNA11) 102359416(GNAQ)
CIN: 445772(cigq)
SPU: 404200(gnaq)
APLC: 110974648
SKO: 100373084
DME: Dmel_CG17759(Galphaq) Dmel_CG17760(CG17760) Dmel_CG30054(CG30054)
DSI: Dsimw501_GD10904(Dsim_GD10904) Dsimw501_GD10905(Dsim_GD10905) Dsimw501_GD10906(Dsim_GD10906)
MDE: 101894482
AAG: 5573467
AME: 550818
BIM: 100743887
BTER: 100647165
SOC: 105197512
AEC: 105153690
ACEP: 105626910
PBAR: 105424768
HST: 105185490
CFO: 105252106
LHU: 105678955
PGC: 109852784
NVI: 100123311
TCA: 654901
NVL: 108569092
BMOR: 692442(Gq)
PMAC: 106720754
PRAP: 110998195
API: 100163208
DNX: 107173102
FCD: 110851332
TUT: 107360534
CEL: CELE_M01D7.7(egl-30)
CBR: CBG22211(Cbr-egl-30)
BMY: Bm1_28970
TSP: Tsp_08128
CRG: 105335187
OBI: 106879472
LAK: 106172369
EPA: 110250860
ADF: 107358199
HMG: 100192224(gnai3)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8836152
  Authors
Johnson GJ, Leis LA, Dunlop PC
  Title
Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences.
  Journal
Biochem J 318 ( Pt 3):1023-31 (1996)
DOI:10.1042/bj3181023
  Sequence
[hsa:2776]

KEGG   ORTHOLOGY: K04635Help
Entry
K04635                      KO                                     

Name
GNA11
Definition
guanine nucleotide-binding protein subunit alpha-11
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04540  Gap junction
ko04725  Cholinergic synapse
ko04730  Long-term depression
ko04911  Insulin secretion
ko04912  GnRH signaling pathway
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04934  Cushing syndrome
ko05142  Chagas disease (American trypanosomiasis)
ko05146  Amoebiasis
ko05163  Human cytomegalovirus infection
ko05200  Pathways in cancer
Disease
H02026  Familial hypocalciuric hypercalcemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   04022 cGMP - PKG signaling pathway
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   04912 GnRH signaling pathway
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   04928 Parathyroid hormone synthesis, secretion and action
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   04925 Aldosterone synthesis and secretion
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   04927 Cortisol synthesis and secretion
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
  09156 Nervous system
   04725 Cholinergic synapse
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   04730 Long-term depression
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
  09166 Endocrine and metabolic diseases
   04934 Cushing syndrome
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
  09167 Infectious diseases
   05163 Human cytomegalovirus infection
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   05146 Amoebiasis
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   05142 Chagas disease (American trypanosomiasis)
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
   04031 GTP-binding proteins
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
  Exosomal proteins of melanoma cells
   K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 3 (Gq/11) [OT]
    K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
BRITE hierarchy
Genes
HSA: 2767(GNA11)
PTR: 100611153(GNA11)
PPS: 100972605(GNA11)
GGO: 101129671(GNA11)
PON: 100460338(GNA11)
NLE: 100584446(GNA11)
MCC: 721649(GNA11)
MCF: 102123885(GNA11)
CSAB: 103233670(GNA11)
RRO: 104665456(GNA11)
RBB: 108512657(GNA11)
CJC: 100386734(GNA11)
SBQ: 101032578(GNA11)
MMU: 14672(Gna11)
RNO: 81662(Gna11)
CGE: 100689065(Gna11)
NGI: 103737243(Gna11)
HGL: 101722520(Gna11)
CCAN: 109691040(Gna11)
TUP: 102479071(GNA11)
CFA: 403914(GNA11)
AML: 100469689(GNA11)
UMR: 103681813(GNA11)
ORO: 101385358(GNA11)
FCA: 101086541(GNA11)
PTG: 107181018(GNA11)
AJU: 106982140(GNA11)
BTA: 281788(GNA11)
BOM: 102287661(GNA11)
BIU: 109561778(GNA11)
PHD: 102320676(GNA11)
CHX: 102177328(GNA11)
OAS: 101119215(GNA11)
SSC: 733588(GNA11)
CFR: 102508599(GNA11)
CDK: 105106041(GNA11)
BACU: 103000262(GNA11)
LVE: 103076924(GNA11)
OOR: 101269696(GNA11)
ECB: 100067327(GNA11)
EPZ: 103543382
EAI: 106832309(GNA11)
MYB: 102259944(GNA11)
MYD: 102771954(GNA11)
HAI: 109388624(GNA11)
RSS: 109453927(GNA11)
PALE: 102888619(GNA11)
LAV: 100675896
TMU: 101345890
MDO: 100009763(GNA11)
SHR: 100920179(GNA11)
OAA: 100084804
GGA: 374077(GNA11)
MGP: 100151748(GNA11)
CJO: 107325609(GNA11)
APLA: 101802177(GNA11)
ACYG: 106049557(GNA11)
TGU: 100219505(GNA11)
GFR: 102043661(GNA11)
FAB: 101818273(GNA11)
PHI: 102102102(GNA11)
PMAJ: 107215591(GNA11)
CCW: 104697002
FPG: 101923890(GNA11)
FCH: 102051778(GNA11)
CLV: 102092243(GNA11)
EGZ: 104124382(GNA11)
AAM: 106486396(GNA11)
ASN: 102385893(GNA11)
AMJ: 102565314(GNA11)
PSS: 102455465(GNA11)
CMY: 102945827(GNA11)
CPIC: 101946431(GNA11)
ACS: 100566521(gna11)
PVT: 110079229(GNA11)
PBI: 103050016
GJA: 107120591
XLA: 380535(gna11.S) 779103(gna11)
XTR: 394755(gna11)
NPR: 108791250(GNA11)
DRE: 493613(gna11b)
MYI: 110465944
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1902575
  Authors
Jiang M, Pandey S, Tran VT, Fong HK
  Title
Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells.
  Journal
Proc Natl Acad Sci U S A 88:3907-11 (1991)
  Sequence
[hsa:2767]
Reference
  Authors
Wettschureck N, Offermanns S.
  Title
Mammalian G proteins and their cell type specific functions.
  Journal
Physiol Rev 85:1159-204 (2005)
DOI:10.1152/physrev.00003.2005

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