KEGG   ORTHOLOGY: K04687
Entry
K04687                      KO                                     

Name
IFNG
Definition
interferon gamma
Pathway
ko03050  Proteasome
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04217  Necroptosis
ko04350  TGF-beta signaling pathway
ko04380  Osteoclast differentiation
ko04612  Antigen processing and presentation
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04657  IL-17 signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04940  Type I diabetes mellitus
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05143  African trypanosomiasis
ko05144  Malaria
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05164  Influenza A
ko05168  Herpes simplex virus 1 infection
ko05200  Pathways in cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05321  Inflammatory bowel disease
ko05322  Systemic lupus erythematosus
ko05323  Rheumatoid arthritis
ko05330  Allograft rejection
ko05332  Graft-versus-host disease
ko05418  Fluid shear stress and atherosclerosis
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H01132  Aplastic anemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    K04687  IFNG; interferon gamma
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K04687  IFNG; interferon gamma
   04630 JAK-STAT signaling pathway
    K04687  IFNG; interferon gamma
   04066 HIF-1 signaling pathway
    K04687  IFNG; interferon gamma
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04687  IFNG; interferon gamma
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K04687  IFNG; interferon gamma
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04687  IFNG; interferon gamma
   04612 Antigen processing and presentation
    K04687  IFNG; interferon gamma
   04660 T cell receptor signaling pathway
    K04687  IFNG; interferon gamma
   04658 Th1 and Th2 cell differentiation
    K04687  IFNG; interferon gamma
   04659 Th17 cell differentiation
    K04687  IFNG; interferon gamma
   04657 IL-17 signaling pathway
    K04687  IFNG; interferon gamma
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04687  IFNG; interferon gamma
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04687  IFNG; interferon gamma
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04687  IFNG; interferon gamma
  09172 Infectious disease: viral
   05160 Hepatitis C
    K04687  IFNG; interferon gamma
   05164 Influenza A
    K04687  IFNG; interferon gamma
   05168 Herpes simplex virus 1 infection
    K04687  IFNG; interferon gamma
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K04687  IFNG; interferon gamma
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K04687  IFNG; interferon gamma
   05144 Malaria
    K04687  IFNG; interferon gamma
   05145 Toxoplasmosis
    K04687  IFNG; interferon gamma
   05140 Leishmaniasis
    K04687  IFNG; interferon gamma
   05142 Chagas disease
    K04687  IFNG; interferon gamma
   05143 African trypanosomiasis
    K04687  IFNG; interferon gamma
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K04687  IFNG; interferon gamma
   05323 Rheumatoid arthritis
    K04687  IFNG; interferon gamma
   05321 Inflammatory bowel disease
    K04687  IFNG; interferon gamma
   05330 Allograft rejection
    K04687  IFNG; interferon gamma
   05332 Graft-versus-host disease
    K04687  IFNG; interferon gamma
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04687  IFNG; interferon gamma
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K04687  IFNG; interferon gamma
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03051 Proteasome
    K04687  IFNG; interferon gamma
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K04687  IFNG; interferon gamma
   00536 Glycosaminoglycan binding proteins
    K04687  IFNG; interferon gamma
Proteasome [BR:ko03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    K04687  IFNG; interferon gamma
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interferons
   K04687  IFNG; interferon gamma
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Cytokines
   K04687  IFNG; interferon gamma
Other DBs
GO: 0005133
Genes
HSA: 3458(IFNG)
PTR: 449517(IFNG)
PPS: 100991779(IFNG)
GGO: 101151755(IFNG)
PON: 100444043(IFNG)
NLE: 100583022(IFNG)
MCC: 574282(IFNG)
MCF: 102128291(IFNG)
CSAB: 103238673(IFNG)
RRO: 104664085(IFNG)
RBB: 108532274(IFNG)
CJC: 100388952(IFNG)
SBQ: 101033464(IFNG)
MMU: 15978(Ifng)
MCAL: 110303854(Ifng)
MPAH: 110326932(Ifng)
RNO: 25712(Ifng)
MUN: 110561827(Ifng)
CGE: 100768486(Ifng)
NGI: 103745085(Ifng)
HGL: 101700722(Ifng)
CCAN: 109676142(Ifng)
OCU: 100008602(IFNG)
TUP: 102470542(IFNG)
CFA: 403801(IFNG)
VVP: 112922237(IFNG)
AML: 100462659(IFNG)
UMR: 103656858(IFNG)
UAH: 113256304(IFNG)
ORO: 101382125(IFNG)
ELK: 111142126
FCA: 493965(IFNG)
PTG: 102963756(IFNG)
PPAD: 109270472(IFNG)
AJU: 106966359(IFNG)
BTA: 281237(IFNG)
BOM: 102267095(IFNG)
BIU: 109558719(IFNG)
BBUB: 102416494(IFNG)
CHX: 100860815(IFNG)
OAS: 443396(IFNG)
SSC: 396991(IFNG)
CFR: 102504614(IFNG)
CDK: 105101111(IFNG)
BACU: 103020304(IFNG)
LVE: 103085542(IFNG)
OOR: 101282933(IFNG)
DLE: 111173770(IFNG)
PCAD: 102981551(IFNG)
ECB: 100034181(IFNG)
EPZ: 103559339(IFNG)
EAI: 106843591(IFNG)
MYB: 102254028(IFNG)
MYD: 102774208(IFNG)
MNA: 107527227(IFNG)
HAI: 109381671(IFNG)
DRO: 112319176(IFNG)
PALE: 102882436(IFNG)
RAY: 107512682(IFNG)
MJV: 108384008(IFNG)
LAV: 100663285(IFNG)
TMU: 101346429
SHR: 105750683(IFNG)
PCW: 110211092(IFNG)
GGA: 396054(IFNG)
MGP: 100543502(IFNG)
CJO: 107310263(IFNG)
NMEL: 110392776(IFNG)
APLA: 101790439(IFNG)
ACYG: 106047018(IFNG)
TGU: 100226664(IFNG)
LSR: 110479845(IFNG)
SCAN: 103820410(IFNG)
GFR: 102042890(IFNG)
FAB: 101811885(IFNG)
PHI: 102099074(IFNG)
PMAJ: 107204252(IFNG)
CCAE: 111937200(IFNG)
CCW: 104698369(IFNG)
ETL: 114062162(IFNG) 114073130
FPG: 101924637(IFNG)
FCH: 102047662(IFNG)
CLV: 102098930(IFNG)
EGZ: 104132906(IFNG)
NNI: 104011009(IFNG)
ACUN: 113491294(IFNG)
PADL: 103919962(IFNG)
AAM: 106488479(IFNG)
ASN: 102383803 102384045
AMJ: 102563354(IFNG)
PSS: 102444608(IFNG)
CMY: 102947470(IFNG)
CPIC: 101934164(IFNG)
PVT: 110075093
PBI: 112540104
PMUR: 107284417(IFNG)
PMUA: 114605540
GJA: 107105706
XLA: 101027283(ifng.L) 108712369
XTR: 100216446(ifng)
DRE: 405790(ifng1)
IPU: 100305073(IFNG) 100526708(ifng)
PHYP: 113532282
SASA: 100329178
ELS: 105017796(ifng1)
SFM: 114909445
CMK: 103186136(ifng)
RTP: 109928154
 » show all
Reference
  Authors
Kunis G, Baruch K, Rosenzweig N, Kertser A, Miller O, Berkutzki T, Schwartz M
  Title
IFN-gamma-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair.
  Journal
Brain 136:3427-40 (2013)
DOI:10.1093/brain/awt259
  Sequence
[hsa:3458]
Reference
PMID:2860101
  Authors
Nishi T, Fujita T, Nishi-Takaoka C, Saito A, Matsumoto T, Sato M, Oka T, Itoh S, Yip YK, Vilcek J, et al.
  Title
Cloning and expression of a novel variant of human interferon-gamma cDNA.
  Journal
J Biochem 97:153-9 (1985)
DOI:10.1093/oxfordjournals.jbchem.a135039
  Sequence
[hsa:3458]

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Ontology (5)   
   KEGG BRITE (4)   
   GO (1)   
Pathway (64)   
   KEGG PATHWAY (64)   
Disease (3)   
   KEGG DISEASE (3)   
Drug (2)   
   KEGG DRUG (2)   
Gene (114)   
   KEGG GENES (112)   
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Literature (2)   
   PubMed (2)   
All databases (190)   

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