KEGG   ORTHOLOGY: K04694Help
Entry
K04694                      KO                                     

Name
SOCS1, JAB
Definition
suppressor of cytokine signaling 1
Pathway
ko04120  Ubiquitin mediated proteolysis
ko04380  Osteoclast differentiation
ko04630  JAK-STAT signaling pathway
ko04910  Insulin signaling pathway
ko04917  Prolactin signaling pathway
ko04930  Type II diabetes mellitus
ko05145  Toxoplasmosis
ko05206  MicroRNAs in cancer
Module
M00388  ECS complex
M00684  JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
   04917 Prolactin signaling pathway
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
  09158 Development
   04380 Osteoclast differentiation
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 09160 Human Diseases
  09161 Cancers
   05206 MicroRNAs in cancer
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
  09167 Infectious diseases
   05145 Toxoplasmosis
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K04694  SOCS1, JAB; suppressor of cytokine signaling 1
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04694  SOCS1, JAB; suppressor of cytokine signaling 1
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04694  SOCS1, JAB; suppressor of cytokine signaling 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04694  SOCS1, JAB; suppressor of cytokine signaling 1
BRITE hierarchy
Genes
HSA: 8651(SOCS1)
PTR: 737070(SOCS1)
GGO: 101131805(SOCS1)
PON: 100445635(SOCS1)
NLE: 100589181(SOCS1)
MCC: 711180(SOCS1)
MCF: 102135411(SOCS1)
CSAB: 103228298(SOCS1)
RRO: 104667710(SOCS1)
RBB: 108541230(SOCS1)
CJC: 100402275(SOCS1)
SBQ: 101050866(SOCS1)
MMU: 12703(Socs1)
RNO: 252971(Socs1)
CGE: 100751218(Socs1)
NGI: 103731577(Socs1)
HGL: 101723330(Socs1)
CCAN: 109676553(Socs1)
OCU: 100339386(SOCS1)
TUP: 102495553(SOCS1)
CFA: 490006(SOCS1)
AML: 100480183(SOCS1)
ORO: 101376722(SOCS1)
FCA: 111558242(SOCS1)
BTA: 518795(SOCS1)
BIU: 109578851(SOCS1)
CHX: 106503587(SOCS1)
OAS: 101107324(SOCS1)
SSC: 100307052(SOCS1)
CDK: 105089066(SOCS1)
BACU: 103000775(SOCS1)
LVE: 103089381(SOCS1)
OOR: 101289479(SOCS1)
ECB: 102148488(SOCS1)
EAI: 106836751(SOCS1)
MYB: 102248245(SOCS1)
MYD: 102772456(SOCS1)
HAI: 109387185(SOCS1)
RSS: 109435893(SOCS1)
PALE: 102878735(SOCS1)
LAV: 100664110(SOCS1)
TMU: 101355851
MDO: 100025389(SOCS1)
SHR: 100917658(SOCS1)
GGA: 416630(SOCS1)
MGP: 100546769(SOCS1)
CJO: 107320828(SOCS1)
APLA: 101801940(SOCS1)
ACYG: 106041226(SOCS1)
TGU: 100228306(SOCS1)
GFR: 102041615(SOCS1)
FAB: 101818258(SOCS1)
PHI: 102099147(SOCS1)
PMAJ: 107211147(SOCS1)
CCW: 104684708(SOCS1)
FPG: 101912887(SOCS1)
FCH: 102054761(SOCS1)
CLV: 102092369(SOCS1)
EGZ: 104123232(SOCS1)
AAM: 106482609(SOCS1)
ASN: 102376072(SOCS1)
AMJ: 102562879(SOCS1)
PSS: 102443510(SOCS1)
CMY: 102932360(SOCS1)
CPIC: 101937678(SOCS1)
ACS: 100560891(socs1)
PVT: 110087059(SOCS1)
PBI: 103067787(SOCS1)
GJA: 107109323(SOCS1)
XLA: 100294520(socs1.L) 108715012 443921(socs1.S)
XTR: 496789(socs1)
NPR: 108798879(SOCS1)
DRE: 445073(socs1a)
IPU: 108258328 108276845(socs1)
AMEX: 103029797(socs1) 103037135
TRU: 100049621(socs1) 101065460
LCO: 104917641(socs1) 104929964
MZE: 101465207(socs1) 101477335
OLA: 100144374(socs1) 101165453
XMA: 102228485 102236178(socs1)
PRET: 103462961 103468587(socs1)
NFU: 107376406(socs1) 107395760
CSEM: 103383624 103393275(socs1)
LCF: 108881078(socs1) 108888466
HCQ: 109511499 109514928(socs1)
BPEC: 110153535 110155763(socs1)
ELS: 105007127(socs1) 105009400
SFM: 108926265 108937273(socs1)
LCM: 102353233(SOCS1) 102354147
CMK: 103173182 103186065(socs1)
VG: 935405(Isaknvgp103)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:8651]
Reference
  Authors
Rui L, Yuan M, Frantz D, Shoelson S, White MF.
  Title
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
  Journal
J Biol Chem 277:42394-8 (2002)
DOI:10.1074/jbc.C200444200
  Sequence
[hsa:8651] [mmu:12703]
Reference
  Authors
Kamizono S, Hanada T, Yasukawa H, Minoguchi S, Kato R, Minoguchi M, Hattori K, Hatakeyama S, Yada M, Morita S, Kitamura T, Kato H, Nakayama Ki, Yoshimura A
  Title
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.
  Journal
J Biol Chem 276:12530-8 (2001)
DOI:10.1074/jbc.M010074200
  Sequence
[hsa:8651]

KEGG   ORTHOLOGY: K04695Help
Entry
K04695                      KO                                     

Name
SOCS2, CIS2
Definition
suppressor of cytokine signaling 2
Pathway
ko04630  JAK-STAT signaling pathway
ko04910  Insulin signaling pathway
ko04917  Prolactin signaling pathway
ko04930  Type II diabetes mellitus
Module
M00388  ECS complex
M00684  JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
   04917 Prolactin signaling pathway
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
 09160 Human Diseases
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
BRITE hierarchy
Genes
HSA: 8835(SOCS2)
PTR: 452127(SOCS2)
PPS: 100989242(SOCS2)
GGO: 101141962(SOCS2)
PON: 100440378(SOCS2)
NLE: 100604289(SOCS2)
MCC: 715772(SOCS2)
MCF: 102125352(SOCS2)
CSAB: 103238870(SOCS2)
RRO: 104678596(SOCS2)
RBB: 108527232(SOCS2)
CJC: 100396208(SOCS2)
SBQ: 101040467(SOCS2)
MMU: 216233(Socs2)
RNO: 84607(Socs2)
NGI: 103726290(Socs2)
HGL: 101716580(Socs2)
CCAN: 109688786(Socs2)
OCU: 100354019(SOCS2)
TUP: 102480737(SOCS2)
CFA: 100855737(SOCS2)
AML: 100474808(SOCS2)
UMR: 103660099(SOCS2)
ORO: 101373719(SOCS2)
FCA: 101080980(SOCS2)
PTG: 102953997(SOCS2)
AJU: 106973415(SOCS2)
BTA: 338437(SOCS2)
BOM: 102268022(SOCS2)
BIU: 109558981(SOCS2)
PHD: 102315362(SOCS2)
CHX: 102178979(SOCS2)
OAS: 101115017(SOCS2)
SSC: 100037966(SOCS2)
CFR: 102505948(SOCS2)
CDK: 105097413(SOCS2)
BACU: 103008379 103018227(SOCS2)
LVE: 103070250(SOCS2)
OOR: 101289153(SOCS2)
ECB: 100051952(SOCS2)
EPZ: 103564583(SOCS2)
EAI: 106831177(SOCS2)
MYB: 102260836(SOCS2)
MYD: 102764738(SOCS2)
HAI: 109392673(SOCS2)
RSS: 109433793(SOCS2)
PALE: 102889529(SOCS2)
LAV: 100660067(SOCS2)
TMU: 101349221
MDO: 100011895(SOCS2)
SHR: 100925364(SOCS2)
OAA: 100079417(SOCS2)
GGA: 395219(SOCS2)
MGP: 100544272(SOCS2)
CJO: 107311591(SOCS2)
APLA: 101790013(SOCS2)
ACYG: 106036904(SOCS2)
TGU: 100229201(SOCS2)
GFR: 102031776(SOCS2)
FAB: 101816040(SOCS2)
PHI: 102114276(SOCS2)
PMAJ: 107204420(SOCS2)
CCW: 104696565(SOCS2)
FPG: 106112815(SOCS2)
FCH: 106631601(SOCS2)
CLV: 102097346(SOCS2)
EGZ: 104132329(SOCS2)
AAM: 106488466(SOCS2)
ASN: 102388356(SOCS2)
AMJ: 102574136(SOCS2)
PSS: 102447309 102453265(SOCS2)
CMY: 102945521(SOCS2) 102945560
CPIC: 101933959 101943086(SOCS2)
ACS: 100552196(socs2)
PVT: 110091701(SOCS2)
PBI: 103051048(SOCS2)
GJA: 107118612(SOCS2)
XLA: 108711062(socs2.L) 734276(socs2.S)
XTR: 100151723(socs2)
NPR: 108790061(SOCS2)
DRE: 562062(socs2)
IPU: 108276077
AMEX: 103034993(socs2)
TRU: 100144308(socs2)
LCO: 104938686(socs2)
NCC: 104961843(socs2)
MZE: 101485857
OLA: 101164124
XMA: 102234649
PRET: 103459817
NFU: 107387837(socs2)
CSEM: 103382466
LCF: 108890543
BPEC: 110161754
SASA: 106567289 106576177(SOCS2a) 106609294(SOCS2b)
ELS: 105027835(socs2)
SFM: 108920753(socs2) 108939161
LCM: 102356616(SOCS2) 102362993
CMK: 103188876(socs2)
SPU: 594503
APLC: 110986036
BMOR: 100862764(SOCS2-12)
PMAC: 106718237
PRAP: 110998970
PXY: 105385539
CRG: 105334011
OBI: 106872107
LAK: 106154562
EPA: 110244417
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:8835]
Reference
  Authors
Iglesias-Gato D, Chuan YC, Wikstrom P, Augsten S, Jiang N, Niu Y, Seipel A, Danneman D, Vermeij M, Fernandez-Perez L, Jenster G, Egevad L, Norstedt G, Flores-Morales A
  Title
SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer.
  Journal
Carcinogenesis 35:24-33 (2014)
DOI:10.1093/carcin/bgt304
  Sequence
[hsa:8835]

KEGG   ORTHOLOGY: K04696Help
Entry
K04696                      KO                                     

Name
SOCS3, CIS3
Definition
suppressor of cytokine signaling 3
Pathway
ko04120  Ubiquitin mediated proteolysis
ko04380  Osteoclast differentiation
ko04630  JAK-STAT signaling pathway
ko04668  TNF signaling pathway
ko04910  Insulin signaling pathway
ko04917  Prolactin signaling pathway
ko04920  Adipocytokine signaling pathway
ko04930  Type II diabetes mellitus
ko04931  Insulin resistance
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05160  Hepatitis C
ko05164  Influenza A
ko05168  Herpes simplex infection
Module
M00388  ECS complex
M00684  JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04668 TNF signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04920 Adipocytokine signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04917 Prolactin signaling pathway
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
  09158 Development
   04380 Osteoclast differentiation
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 09160 Human Diseases
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   04931 Insulin resistance
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
  09167 Infectious diseases
   05164 Influenza A
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   05160 Hepatitis C
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
   05168 Herpes simplex infection
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
BRITE hierarchy
Genes
HSA: 9021(SOCS3)
PTR: 454921(SOCS3)
PPS: 100978589(SOCS3)
GGO: 101123839(SOCS3)
PON: 100446544(SOCS3)
MCC: 715680(SOCS3)
MCF: 102121569(SOCS3)
CSAB: 103243658(SOCS3)
RRO: 104677022(SOCS3)
RBB: 108517203(SOCS3)
CJC: 100398838(SOCS3)
SBQ: 101046533(SOCS3)
MMU: 12702(Socs3)
RNO: 89829(Socs3)
CGE: 100769267(Socs3)
NGI: 103747288(Socs3)
HGL: 101704157(Socs3)
CCAN: 109683139(Socs3)
OCU: 103346588(SOCS3)
TUP: 102486692(SOCS3)
CFA: 442949(SOCS3)
AML: 100475555(SOCS3)
UMR: 103665967(SOCS3)
ORO: 101364487(SOCS3)
FCA: 101081846(SOCS3)
BTA: 282081(SOCS3)
BOM: 102273017(SOCS3)
BIU: 109574319(SOCS3)
PHD: 102315804(SOCS3)
CHX: 102187711(SOCS3)
OAS: 100294595(SOCS3)
SSC: 493186(SOCS3)
CFR: 102518913(SOCS3)
CDK: 105092151(SOCS3)
BACU: 103013097(SOCS3)
LVE: 103071774(SOCS3)
OOR: 101284843(SOCS3)
ECB: 100050730(SOCS3)
EPZ: 103554055(SOCS3)
EAI: 106845267(SOCS3)
MYB: 102252296(SOCS3)
MYD: 102763837(SOCS3)
HAI: 109383617(SOCS3)
RSS: 109449408(SOCS3)
PALE: 102887834(SOCS3)
LAV: 100670741(SOCS3)
TMU: 101348420
MDO: 100026656(SOCS3)
SHR: 100934360(SOCS3)
OAA: 100090302(SOCS3)
GGA: 395299(SOCS3)
MGP: 100547594(SOCS3)
CJO: 107322171(SOCS3)
APLA: 101791200(SOCS3)
ACYG: 106046730(SOCS3)
TGU: 100227853(SOCS3)
GFR: 102044994(SOCS3)
FAB: 101810199(SOCS3)
PHI: 102107383(SOCS3)
PMAJ: 107212347(SOCS3)
FPG: 101912299(SOCS3)
FCH: 102058593(SOCS3)
CLV: 102085285(SOCS3)
AAM: 106487124(SOCS3)
ASN: 102386715(SOCS3)
AMJ: 102568555(SOCS3) 102570761
PSS: 102446993(SOCS3)
CMY: 102930798(SOCS3)
CPIC: 101947835 101953847(SOCS3)
ACS: 100560082 100564374(socs3)
PVT: 110078594 110090429(SOCS3)
PBI: 103057222 103064119(SOCS3)
GJA: 107113150 107115315(SOCS3)
XLA: 100158303 108696746 380467(socs3.S) 414533(socs3.L)
XTR: 394588(socs3) 448204(socs3)
NPR: 108801343 108801441(SOCS3)
DRE: 406596(socs3b)
IPU: 100528984(socs3) 108274104
TRU: 101079037 778006(socs3)
MZE: 101468895(socs3) 101479458
OLA: 101170518(socs3) 101170961(socs3)
PRET: 103461355 103481519(socs3)
NFU: 107387732(socs3)
CSEM: 103381769 103392817(socs3)
LCF: 108876107 108902726(socs3)
HCQ: 109519371(socs3) 109527547
ELS: 105013055(socs3) 105021322
SFM: 108922562 108924821(socs3)
LCM: 102346594(SOCS3) 102360670
CMK: 103175554(socs3)
ADF: 107353946
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:9021]
Reference
  Authors
Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI.
  Title
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
  Journal
Genes Dev 18:3055-65 (2004)
DOI:10.1101/gad.1252404
  Sequence
[hsa:9021]
Reference
  Authors
Rui L, Yuan M, Frantz D, Shoelson S, White MF.
  Title
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
  Journal
J Biol Chem 277:42394-8 (2002)
DOI:10.1074/jbc.C200444200
  Sequence
[hsa:9021] [mmu:12702]

KEGG   ORTHOLOGY: K04697Help
Entry
K04697                      KO                                     

Name
SOCS4
Definition
suppressor of cytokine signaling 4
Pathway
ko04630  JAK-STAT signaling pathway
ko04910  Insulin signaling pathway
ko04917  Prolactin signaling pathway
ko04930  Type II diabetes mellitus
Module
M00388  ECS complex
M00684  JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K04697  SOCS4; suppressor of cytokine signaling 4
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K04697  SOCS4; suppressor of cytokine signaling 4
   04917 Prolactin signaling pathway
    K04697  SOCS4; suppressor of cytokine signaling 4
 09160 Human Diseases
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04697  SOCS4; suppressor of cytokine signaling 4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K04697  SOCS4; suppressor of cytokine signaling 4
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00388  ECS complex
     K04697  SOCS4; suppressor of cytokine signaling 4
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K04697  SOCS4; suppressor of cytokine signaling 4
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     K04697  SOCS4; suppressor of cytokine signaling 4
BRITE hierarchy
Genes
HSA: 122809(SOCS4)
PTR: 452919(SOCS4)
PPS: 100989690(SOCS4)
GGO: 101131192(SOCS4)
PON: 100171842(SOCS4)
NLE: 100590972(SOCS4)
MCC: 696146(SOCS4)
MCF: 102141350(SOCS4)
CSAB: 103229025(SOCS4)
RRO: 104669147(SOCS4)
RBB: 108530661(SOCS4)
CJC: 100386210(SOCS4)
SBQ: 101034850(SOCS4)
MMU: 67296(Socs4)
RNO: 305828(Socs4)
CGE: 100750379(Socs4)
NGI: 103739222(Socs4)
HGL: 101704725(Socs4)
CCAN: 109693954(Socs4)
OCU: 100357417(SOCS4)
TUP: 102468675(SOCS4)
CFA: 100687271(SOCS4)
AML: 100464791(SOCS4)
UMR: 103673077(SOCS4)
ORO: 101383881(SOCS4)
FCA: 101080974(SOCS4)
PTG: 102971697(SOCS4)
AJU: 106984332(SOCS4)
BTA: 540412(SOCS4)
BOM: 102270424(SOCS4)
BIU: 109565183(SOCS4)
PHD: 102333116(SOCS4)
CHX: 102185842(SOCS4)
OAS: 101117935(SOCS4)
SSC: 100302366(SOCS4)
CFR: 102515584(SOCS4)
CDK: 105091440(SOCS4)
BACU: 103014060(SOCS4)
LVE: 103076129(SOCS4)
OOR: 101275711(SOCS4)
ECB: 100050301(SOCS4)
EPZ: 103554102(SOCS4)
EAI: 106846111(SOCS4)
MYB: 102247430(SOCS4)
MYD: 102767035(SOCS4)
HAI: 109384171(SOCS4)
RSS: 109444383(SOCS4)
PALE: 102879275(SOCS4)
LAV: 100662743(SOCS4)
TMU: 101358025
MDO: 100024207(SOCS4)
SHR: 100921040(SOCS4)
OAA: 100091294
GGA: 423557(SOCS4)
MGP: 100549827(SOCS4)
CJO: 107315453(SOCS4)
APLA: 101804231(SOCS4)
ACYG: 106044059(SOCS4)
TGU: 100230629(SOCS4)
GFR: 102043937(SOCS4)
FAB: 101815072(SOCS4) 101816294
PHI: 102109006(SOCS4)
PMAJ: 107206463(SOCS4)
CCW: 104687619(SOCS4)
FPG: 101924304(SOCS4)
FCH: 102048310(SOCS4)
CLV: 102086690(SOCS4)
EGZ: 104122986(SOCS4)
AAM: 106493674(SOCS4)
ASN: 102384587(SOCS4)
AMJ: 102572731(SOCS4)
PSS: 102453072(SOCS4)
CMY: 102931468(SOCS4)
CPIC: 101953043(SOCS4)
ACS: 100561266(socs4)
PVT: 110070093(SOCS4)
PBI: 103053679(SOCS4)
GJA: 107113082(SOCS4)
XLA: 108698764(socs4.L) 108699788(socs4.S)
XTR: 549828(socs4)
NPR: 108789412(SOCS4)
DRE: 100003691(socs9)
IPU: 108270091(SOCS4)
AMEX: 103045167
TRU: 100144313(socs4)
LCO: 104929608(socs4)
NCC: 104964293
MZE: 101469365
OLA: 100144385(socs4)
XMA: 102232061
PRET: 103462934
NFU: 107381831
CSEM: 103398397
LCF: 108888048(socs4)
HCQ: 109514287
SASA: 106602930(socs4)
ELS: 105023278(socs4)
SFM: 108919519
LCM: 102362805(SOCS4)
CMK: 103175235(socs4)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:122809]
Reference
  Authors
Kario E, Marmor MD, Adamsky K, Citri A, Amit I, Amariglio N, Rechavi G, Yarden Y
  Title
Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling.
  Journal
J Biol Chem 280:7038-48 (2005)
DOI:10.1074/jbc.M408575200
  Sequence
[hsa:122809]

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