KEGG   ORTHOLOGY: K05098Help
Entry
K05098                      KO                                     

Name
KDR, VEGFR2, CD309
Definition
kinase insert domain protein receptor [EC:2.7.10.1]
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04370  VEGF signaling pathway
ko04510  Focal adhesion
ko05205  Proteoglycans in cancer
ko05418  Fluid shear stress and atherosclerosis
Disease
H01482  Infantile hemangioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
   04015 Rap1 signaling pathway
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
   04010 MAPK signaling pathway
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
   04370 VEGF signaling pathway
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
   04151 PI3K-Akt signaling pathway
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
 09160 Human Diseases
  09161 Cancers
   05205 Proteoglycans in cancer
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
  09165 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
  09168 Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
  09183 Protein families: signaling and cellular processes
   04090 CD Molecules
    K05098  CD309, KDR; kinase insert domain receptor (a type III receptor tyrosine kinase)
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  VEGFR family [OT]
   K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor
CD molecules [BR:ko04090]
 Proteins
  K05098  CD309, KDR; kinase insert domain receptor (a type III receptor tyrosine kinase)
BRITE hierarchy
Genes
HSA: 3791(KDR)
PTR: 461315(KDR)
PPS: 100986594(KDR)
GGO: 101127110(KDR)
PON: 100462446(KDR)
NLE: 100604569(KDR)
MCC: 698293(KDR)
MCF: 102136227(KDR)
CSAB: 103235670(KDR)
RRO: 104662002(KDR)
RBB: 108531591(KDR)
CJC: 100407045(KDR)
SBQ: 101036336(KDR)
MMU: 16542(Kdr)
RNO: 25589(Kdr)
CGE: 100756294(Kdr)
NGI: 103734390(Kdr)
HGL: 101726029(Kdr)
CCAN: 109698964(Kdr)
OCU: 100008607(KDR)
TUP: 102489981(KDR)
CFA: 482154(KDR)
AML: 100484938(KDR)
UMR: 103672740(KDR)
ORO: 101371459(KDR)
FCA: 101090260(KDR)
PTG: 102955197(KDR)
AJU: 106983987(KDR)
BTA: 407170(KDR)
BOM: 102288007(KDR)
BIU: 109560478(KDR)
PHD: 102330690(KDR)
CHX: 100860836(KDR)
OAS: 443087(KDR)
SSC: 397311(KDR)
CFR: 102520881(KDR)
CDK: 105091598(KDR)
BACU: 102999852(KDR)
LVE: 103087802(KDR)
OOR: 101290288(KDR)
ECB: 100033959(KDR)
EPZ: 103554974(KDR)
EAI: 106836923(KDR)
MYB: 102256532(KDR)
MYD: 102760801(KDR)
HAI: 109381812(KDR)
RSS: 109451716(KDR)
PALE: 102896638(KDR)
LAV: 100656232(KDR)
TMU: 101348626
MDO: 100017311(KDR)
SHR: 100929091(KDR)
OAA: 100075389(KDR)
GGA: 395323(KDR)
MGP: 100542630
CJO: 107313758(KDR)
APLA: 101797579(KDR)
ACYG: 106030825(KDR)
TGU: 100231879(KDR)
GFR: 102042381(KDR)
FAB: 101821250(KDR)
PHI: 102113293(KDR)
PMAJ: 107202958(KDR)
CCW: 104690864(KDR)
FPG: 101920584(KDR)
FCH: 102059103(KDR)
CLV: 102095316(KDR)
EGZ: 104129460(KDR)
ASN: 102384502(KDR)
AMJ: 102567818(KDR)
PSS: 102451309(KDR)
CMY: 102936088(KDR)
CPIC: 101936813(KDR)
ACS: 100551738(kdr)
PVT: 110078415(KDR)
PBI: 103063796(KDR)
GJA: 107106034(KDR)
XLA: 108698463 108706593(kdr.S)
XTR: 100487501(kdr)
NPR: 108803904(KDR)
DRE: 554230(kdr)
IPU: 108258084(kdr)
AMEX: 103022603(kdr)
TRU: 101073989(kdr)
LCO: 104919091(kdr)
NCC: 104947077(kdr)
MZE: 101472847(kdr)
OLA: 101162439(kdr)
XMA: 102225837(kdr)
PRET: 103463836(kdr)
NFU: 107393390(kdr)
CSEM: 103376704(kdr)
LCF: 108879132(kdr) 108894371
HCQ: 109532106(kdr)
BPEC: 110154739(kdr)
SASA: 106584120(kdr)
ELS: 105011839(kdr)
SFM: 108922800(kdr)
LCM: 102362684(KDR)
CMK: 103178168(kdr)
NVI: 100123205
HMG: 100214305
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1656371
  Authors
Terman BI, Carrion ME, Kovacs E, Rasmussen BA, Eddy RL, Shows TB
  Title
Identification of a new endothelial cell growth factor receptor tyrosine kinase.
  Journal
Oncogene 6:1677-83 (1991)
  Sequence
[hsa:3791]
Reference
  Authors
Stuttfeld E, Ballmer-Hofer K
  Title
Structure and function of VEGF receptors.
  Journal
IUBMB Life 61:915-22 (2009)
DOI:10.1002/iub.234

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