KEGG   ORTHOLOGY: K05208Help
Entry
K05208                      KO                                     

Name
GRIN1
Definition
glutamate receptor ionotropic, NMDA 1
Pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis (ALS)
ko05016  Huntington disease
ko05030  Cocaine addiction
ko05031  Amphetamine addiction
ko05033  Nicotine addiction
ko05034  Alcoholism
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04015 Rap1 signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04020 Calcium signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04024 cAMP signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04720 Long-term potentiation
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05014 Amyotrophic lateral sclerosis (ALS)
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05016 Huntington disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  09164 Substance dependence
   05030 Cocaine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05031 Amphetamine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05033 Nicotine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05034 Alcoholism
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
Ion channels [BR:ko04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
BRITE hierarchy
Other DBs
GO: 0004972 0005234
TC: 1.A.10.1.6 1.A.10.1.12
Genes
HSA: 2902(GRIN1)
PTR: 465176(GRIN1)
PPS: 100987673(GRIN1)
GGO: 101146203(GRIN1)
PON: 100435177(GRIN1)
NLE: 100607572(GRIN1)
MCC: 574380(GRIN1)
MCF: 102115033(GRIN1)
CSAB: 103239575(GRIN1)
RRO: 104669771(GRIN1)
RBB: 108542864(GRIN1)
CJC: 100413857(GRIN1)
SBQ: 101054145(GRIN1)
MMU: 14810(Grin1)
RNO: 24408(Grin1)
CGE: 100770880(Grin1)
NGI: 103732604(Grin1)
HGL: 101720185(Grin1)
TUP: 102469683(GRIN1)
CFA: 494007(GRIN1)
AML: 100465687(GRIN1)
UMR: 103675310(GRIN1)
ORO: 101368224(GRIN1)
FCA: 101082021(GRIN1)
PTG: 102949242(GRIN1)
AJU: 106989187(GRIN1)
BTA: 100336579(GRIN1)
BOM: 102276953(GRIN1)
PHD: 102324204(GRIN1)
CHX: 102181789(GRIN1)
OAS: 443281(GRIN1)
CFR: 102506181(GRIN1)
CDK: 105106183(GRIN1)
BACU: 103001022(GRIN1)
LVE: 103085162(GRIN1)
OOR: 101278622(GRIN1)
ECB: 100059861(GRIN1)
EPZ: 103563588(GRIN1)
EAI: 106822778(GRIN1)
MYB: 102240692(GRIN1)
MYD: 102751770(GRIN1)
HAI: 109382502(GRIN1)
RSS: 109460938(GRIN1)
PALE: 102894415(GRIN1)
LAV: 100663779(GRIN1)
TMU: 101349517
MDO: 100023485(GRIN1)
SHR: 100922600(GRIN1)
OAA: 100082705(GRIN1)
GGA: 404296(GRIN1)
MGP: 100548054(GRIN1)
CJO: 107321672(GRIN1)
APLA: 101789524(GRIN1)
ACYG: 106037054(GRIN1)
TGU: 751779(GRIN1)
GFR: 102040955(GRIN1)
FAB: 101818610(GRIN1)
PHI: 102108893(GRIN1)
PMAJ: 107212141(GRIN1)
CCW: 104688213(GRIN1)
FPG: 101913185(GRIN1)
FCH: 102047364(GRIN1)
CLV: 102098434(GRIN1)
EGZ: 104123999(GRIN1)
AAM: 106487018(GRIN1)
ASN: 102370900(GRIN1)
AMJ: 102571725(GRIN1)
PSS: 102453445(GRIN1)
CMY: 102936758
CPIC: 101935314(GRIN1)
ACS: 100553024(grin1)
PVT: 110087451(GRIN1)
PBI: 103066289(GRIN1)
GJA: 107115159(GRIN1)
XLA: 108699855 397953(grin1.S)
XTR: 780048(grin1)
NPR: 108795933(GRIN1)
DRE: 100005675(grin1b) 767745(grin1a)
IPU: 108255876(grin1) 108278500
TRU: 101064941(grin1) 101074532
LCO: 104936329(grin1)
NCC: 104966793(grin1) 104966795
BPEC: 110159188 110164000(grin1)
SFM: 108922658 108938618(grin1)
LCM: 102356038(GRIN1)
CMK: 103183009(grin1)
CIN: 100186847
APLC: 110991116
SKO: 100370156
DME: Dmel_CG2902(Nmdar1)
DSI: Dsimw501_GD19612(Dsim_GD19612)
MDE: 101898320
AAG: 5570802
AME: 406079(Nmdar1)
BIM: 100749947
BTER: 100644436
SOC: 105201093
AEC: 105145837
ACEP: 105618959
PBAR: 105434122
HST: 105182141
CFO: 105258574
LHU: 105668471
PGC: 109857911
TCA: 658152
DPA: 109537645
NVL: 108562030
BMOR: 101743090
PMAC: 106715411
PRAP: 110995370
PXY: 105389024
API: 100160524
DNX: 107162112
ZNE: 110837591
FCD: 110851005
CEL: CELE_F07F6.6(nmr-1)
CBR: CBG02401(Cbr-nmr-1)
CRG: 105333721
MYI: 110451795
OBI: 106884058
LAK: 106178045
SHX: MS3_00804
ADF: 107354805
HMG: 100197210
HAN: 110885870
NGR: NAEGRDRAFT_58252(FM167)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7685113
  Authors
Planells-Cases R, Sun W, Ferrer-Montiel AV, Montal M
  Title
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
  Journal
Proc Natl Acad Sci U S A 90:5057-61 (1993)
DOI:10.1073/pnas.90.11.5057
  Sequence
[hsa:2902]

KEGG   ORTHOLOGY: K05209Help
Entry
K05209                      KO                                     

Name
GRIN2A
Definition
glutamate receptor ionotropic, NMDA 2A
Pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko04728  Dopaminergic synapse
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis (ALS)
ko05030  Cocaine addiction
ko05031  Amphetamine addiction
ko05033  Nicotine addiction
ko05034  Alcoholism
ko05322  Systemic lupus erythematosus
Disease
H01514  Landau-Kleffner syndrome
H01827  Epileptic encephalopathy with continuous spike-waves during slow-wave sleep
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04015 Rap1 signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04020 Calcium signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04024 cAMP signaling pathway
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04728 Dopaminergic synapse
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   04720 Long-term potentiation
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  09159 Environmental adaptation
   04713 Circadian entrainment
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
 09160 Human Diseases
  09162 Immune diseases
   05322 Systemic lupus erythematosus
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05014 Amyotrophic lateral sclerosis (ALS)
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
  09164 Substance dependence
   05030 Cocaine addiction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05031 Amphetamine addiction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05033 Nicotine addiction
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
   05034 Alcoholism
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
Ion channels [BR:ko04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
BRITE hierarchy
Other DBs
GO: 0004972 0005234
TC: 1.A.10.1.6
Genes
HSA: 2903(GRIN2A)
PTR: 454396(GRIN2A)
PPS: 100977852(GRIN2A)
GGO: 101124569(GRIN2A)
PON: 100438553(GRIN2A)
NLE: 100584731(GRIN2A)
MCC: 100429880(GRIN2A)
MCF: 102123126(GRIN2A)
CSAB: 103228072(GRIN2A)
RRO: 104667722(GRIN2A)
RBB: 108541249(GRIN2A)
CJC: 100411569(GRIN2A)
SBQ: 101030380(GRIN2A)
MMU: 14811(Grin2a)
RNO: 24409(Grin2a)
CGE: 100764315(Grin2a)
NGI: 103731589(Grin2a)
HGL: 101716707(Grin2a)
OCU: 100337889(GRIN2A)
TUP: 102487925(GRIN2A)
CFA: 490012(GRIN2A)
AML: 100469843(GRIN2A)
UMR: 103668590(GRIN2A)
ORO: 101378928(GRIN2A)
FCA: 101086110(GRIN2A)
PTG: 102969126(GRIN2A)
AJU: 106989347
BTA: 524212(GRIN2A)
BOM: 102283831(GRIN2A)
BIU: 109578088(GRIN2A)
PHD: 102324750(GRIN2A)
CHX: 102189537(GRIN2A)
OAS: 101106989(GRIN2A)
SSC: 100736832(GRIN2A)
CFR: 102503788(GRIN2A)
CDK: 105089056(GRIN2A)
BACU: 103006151(GRIN2A)
LVE: 103091670(GRIN2A)
OOR: 101270526(GRIN2A)
ECB: 100051329(GRIN2A)
EPZ: 103555146(GRIN2A)
EAI: 106836764
MYB: 102245838(GRIN2A)
MYD: 102771313(GRIN2A)
HAI: 109387184(GRIN2A)
RSS: 109437945(GRIN2A) 109438391
PALE: 102898336(GRIN2A)
TMU: 101353799
MDO: 100018255(GRIN2A)
SHR: 100920008(GRIN2A)
OAA: 100074436(GRIN2A)
GGA: 427678(GRIN2A)
MGP: 100549076
CJO: 107320868(GRIN2A)
APLA: 101804769(GRIN2A)
ACYG: 106041218(GRIN2A)
TGU: 778440(GRIN2A)
GFR: 102042287(GRIN2A)
FAB: 101819385(GRIN2A)
PHI: 102113741(GRIN2A)
PMAJ: 107211300(GRIN2A)
CCW: 104684701(GRIN2A)
FPG: 101912351(GRIN2A)
FCH: 102048497(GRIN2A)
CLV: 102091639(GRIN2A)
EGZ: 104123229(GRIN2A)
AAM: 106482645(GRIN2A)
ASN: 102373605(GRIN2A)
AMJ: 102565271(GRIN2A)
PSS: 102459849(GRIN2A)
CMY: 102936101(GRIN2A)
CPIC: 101933703(GRIN2A)
ACS: 100557524(grin2a)
PVT: 110087033(GRIN2A)
PBI: 103060162(GRIN2A)
GJA: 107111188(GRIN2A)
XLA: 100126660(nr2a) 100127346(grin2a.L)
XTR: 100489006(grin2a)
NPR: 108794358(GRIN2A)
DRE: 563297(grin2aa) 570493(grin2ab)
IPU: 108258284 108274125(grin2a)
AMEX: 103038109 103042056(grin2a)
TRU: 101061712(grin2a) 101069083
LCO: 104917658(grin2a) 104921203
MZE: 101467440 101485837(grin2a)
OLA: 101161811(grin2a) 101164378
XMA: 102226347 102237459(grin2a)
NFU: 107376713(grin2a) 107388927
CSEM: 103383503 103393273(grin2a)
LCF: 108881068(grin2a) 108899387
HCQ: 109511254 109514843(grin2a)
BPEC: 110158275 110160561(grin2a)
SASA: 106563992
ELS: 105009144 105013466(grin2a)
SFM: 108926533 108937395(grin2a)
LCM: 102359367(GRIN2A)
CMK: 103186084(grin2a)
CIN: 101242030
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8428958
  Authors
Ishii T, Moriyoshi K, Sugihara H, Sakurada K, Kadotani H, Yokoi M, Akazawa C, Shigemoto R, Mizuno N, Masu M, et al.
  Title
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
  Journal
J Biol Chem 268:2836-43 (1993)
  Sequence
[rno:24409]

KEGG   ORTHOLOGY: K05211Help
Entry
K05211                      KO                                     

Name
GRIN2C
Definition
glutamate receptor ionotropic, NMDA 2C
Pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis (ALS)
ko05030  Cocaine addiction
ko05031  Amphetamine addiction
ko05033  Nicotine addiction
ko05034  Alcoholism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   04024 cAMP signaling pathway
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   04720 Long-term potentiation
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
  09159 Environmental adaptation
   04713 Circadian entrainment
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05014 Amyotrophic lateral sclerosis (ALS)
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
  09164 Substance dependence
   05030 Cocaine addiction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05031 Amphetamine addiction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05033 Nicotine addiction
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
   05034 Alcoholism
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
Ion channels [BR:ko04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
BRITE hierarchy
Other DBs
GO: 0004972 0005234
TC: 1.A.10.1.3 1.A.10.1.6
Genes
HSA: 2905(GRIN2C)
PTR: 454868(GRIN2C)
PPS: 100989438(GRIN2C)
GGO: 101146970(GRIN2C)
PON: 100436723(GRIN2C)
NLE: 100607001(GRIN2C)
MCC: 699216(GRIN2C)
MCF: 102135755(GRIN2C)
CSAB: 103243074(GRIN2C)
RRO: 104681333(GRIN2C)
RBB: 108537403(GRIN2C)
CJC: 100388195(GRIN2C)
SBQ: 101040894(GRIN2C)
MMU: 14813(Grin2c)
RNO: 24411(Grin2c)
CGE: 100758804(Grin2c)
NGI: 103732757(Grin2c)
HGL: 101698922(Grin2c)
CCAN: 109683576(Grin2c)
OCU: 100356338(GRIN2C)
TUP: 102479118(GRIN2C)
CFA: 483302(GRIN2C)
AML: 100475562(GRIN2C)
UMR: 103665926(GRIN2C)
ORO: 101369978(GRIN2C)
FCA: 101091740(GRIN2C)
PTG: 102959236(GRIN2C)
AJU: 106987730(GRIN2C)
BTA: 535158(GRIN2C)
BOM: 102272710(GRIN2C)
BIU: 109573357(GRIN2C)
PHD: 102325114(GRIN2C)
CHX: 102177097(GRIN2C)
OAS: 101102915(GRIN2C)
SSC: 100515684(GRIN2C)
CFR: 102516268(GRIN2C)
CDK: 105104658(GRIN2C)
BACU: 103008767(GRIN2C)
LVE: 103086451(GRIN2C)
OOR: 101286467(GRIN2C)
ECB: 100052410(GRIN2C)
EPZ: 103546604(GRIN2C)
EAI: 106830197(GRIN2C)
MYB: 102264015(GRIN2C)
MYD: 102775005(GRIN2C)
HAI: 109383627(GRIN2C)
RSS: 109454718(GRIN2C)
PALE: 102881285(GRIN2C)
LAV: 100656237(GRIN2C)
TMU: 101355341
MDO: 100028018(GRIN2C)
SHR: 100922827(GRIN2C)
GGA: 431090(GRIN2C)
MGP: 100540247(GRIN2C)
CJO: 107322357(GRIN2C)
APLA: 101800611(GRIN2C)
ACYG: 106034618(GRIN2C)
TGU: 778441(GRIN2C)
GFR: 102034349(GRIN2C)
FAB: 101812781(GRIN2C)
PHI: 102102883(GRIN2C)
PMAJ: 107212243(GRIN2C)
CCW: 104694369(GRIN2C)
FPG: 101910725(GRIN2C)
FCH: 102046514(GRIN2C)
CLV: 102089298(GRIN2C)
EGZ: 104125333(GRIN2C)
AAM: 106492603(GRIN2C)
ASN: 102372791(GRIN2C)
AMJ: 102563653(GRIN2C)
PSS: 102458166(GRIN2C)
CMY: 102939529(GRIN2C)
CPIC: 101952683(GRIN2C)
ACS: 100560039(grin2c)
PVT: 110085794(GRIN2C)
PBI: 103061309
GJA: 107110013(GRIN2C)
XLA: 108701104(NR2C) 108702800
XTR: 100496638(grin2c)
NPR: 108797027(GRIN2C)
DRE: 100333648(grin2cb)
IPU: 108273492 108274822(grin2c)
TRU: 101068341 101074781(grin2c)
LCO: 104923387(grin2c) 104923413
OLA: 101159589(grin2c) 101166504
NFU: 107378608 107387701(grin2c)
CSEM: 103381827 103392564(grin2c)
BPEC: 110161119(grin2c) 110171215
LCM: 102364888(GRIN2C)
CMK: 103175724(grin2c)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8428958
  Authors
Ishii T, Moriyoshi K, Sugihara H, Sakurada K, Kadotani H, Yokoi M, Akazawa C, Shigemoto R, Mizuno N, Masu M, et al.
  Title
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
  Journal
J Biol Chem 268:2836-43 (1993)
  Sequence
[rno:24411]

KEGG   ORTHOLOGY: K05212Help
Entry
K05212                      KO                                     

Name
GRIN2D
Definition
glutamate receptor ionotropic, NMDA 2D
Pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis (ALS)
ko05030  Cocaine addiction
ko05031  Amphetamine addiction
ko05033  Nicotine addiction
ko05034  Alcoholism
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   04024 cAMP signaling pathway
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   04720 Long-term potentiation
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
  09159 Environmental adaptation
   04713 Circadian entrainment
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05014 Amyotrophic lateral sclerosis (ALS)
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
  09164 Substance dependence
   05030 Cocaine addiction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05031 Amphetamine addiction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05033 Nicotine addiction
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
   05034 Alcoholism
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
Ion channels [BR:ko04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
BRITE hierarchy
Other DBs
GO: 0004972 0005234
TC: 1.A.10.1
Genes
HSA: 2906(GRIN2D)
PTR: 456180(GRIN2D)
PPS: 100977548(GRIN2D)
GGO: 101128942(GRIN2D)
PON: 100438953(GRIN2D)
NLE: 100589972(GRIN2D)
MCC: 717945(GRIN2D)
MCF: 102142969(GRIN2D)
CSAB: 103234973(GRIN2D)
RRO: 104666582(GRIN2D)
RBB: 108523108(GRIN2D) 108525579
CJC: 100401859(GRIN2D)
SBQ: 101036810(GRIN2D)
MMU: 14814(Grin2d)
RNO: 24412(Grin2d)
CGE: 100750615(Grin2d)
NGI: 103743747(Grin2d)
HGL: 101710918(Grin2d)
CCAN: 109682664(Grin2d)
TUP: 102498157(GRIN2D)
CFA: 484405(GRIN2D)
AML: 100473622(GRIN2D)
UMR: 103657232(GRIN2D)
ORO: 101383267(GRIN2D)
FCA: 101095061(GRIN2D)
PTG: 102960299(GRIN2D)
AJU: 106986956(GRIN2D)
BTA: 618181(GRIN2D)
BOM: 102266852(GRIN2D)
BIU: 109571774(GRIN2D)
PHD: 102322225(GRIN2D)
CHX: 102177187(GRIN2D)
OAS: 101105943(GRIN2D)
SSC: 100521797(GRIN2D)
CFR: 102522985(GRIN2D)
CDK: 105098957(GRIN2D)
BACU: 103006149(GRIN2D)
LVE: 103076743(GRIN2D)
OOR: 101270626(GRIN2D)
EPZ: 103541380(GRIN2D)
EAI: 106838305(GRIN2D)
MYB: 102257658(GRIN2D)
MYD: 102765234(GRIN2D)
HAI: 109390975(GRIN2D)
RSS: 109452505(GRIN2D)
PALE: 102887718(GRIN2D)
LAV: 100653538(GRIN2D)
TMU: 101358510
MDO: 100033038(GRIN2D)
CJO: 107307479
ACYG: 106049304
GFR: 102038772
FAB: 101820854
PHI: 102106210(GRIN2D)
FPG: 101910546
FCH: 102049686
ASN: 102372349(GRIN2D)
AMJ: 102573615(GRIN2D)
PSS: 102460750(GRIN2D)
CMY: 102931194(GRIN2D)
CPIC: 101943360(GRIN2D)
ACS: 100556989(grin2d)
PVT: 110081819(GRIN2D)
PBI: 103048165(GRIN2D)
GJA: 107113157(GRIN2D)
XLA: 100126609(grin2d.L) 108697266
XTR: 100496465(grin2d)
NPR: 108784206(GRIN2D)
DRE: 100149482 449864(grin2da)
CSEM: 103387867(grin2d) 103393819
LCM: 102365417(GRIN2D)
EPA: 110239269
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9489750
  Authors
Hess SD, Daggett LP, Deal C, Lu CC, Johnson EC, Velicelebi G
  Title
Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors.
  Journal
J Neurochem 70:1269-79 (1998)
DOI:10.1046/j.1471-4159.1998.70031269.x
  Sequence
[hsa:2906]

KEGG   ORTHOLOGY: K05215Help
Entry
K05215                      KO                                     

Name
P2RX1
Definition
P2X purinoceptor 1
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04611  Platelet activation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05215  P2RX1; P2X purinoceptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05215  P2RX1; P2X purinoceptor 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K05215  P2RX1; P2X purinoceptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05215  P2RX1; P2X purinoceptor 1
Ion channels [BR:ko04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05215  P2RX1; P2X purinoceptor 1
BRITE hierarchy
Other DBs
GO: 0001614 0004931
TC: 1.A.7.1.1
Genes
HSA: 5023(P2RX1)
PTR: 454439(P2RX1)
PPS: 100994570(P2RX1)
GGO: 101124328(P2RX1)
PON: 100450049(P2RX1)
NLE: 100595361(P2RX1)
MCC: 707658(P2RX1)
MCF: 102146852(P2RX1)
CSAB: 103242171(P2RX1)
RRO: 104677227(P2RX1)
RBB: 108520720(P2RX1)
CJC: 100414268(P2RX1)
SBQ: 101034335(P2RX1)
MMU: 18436(P2rx1)
RNO: 25505(P2rx1)
CGE: 100756069(P2rx1)
NGI: 103751989(P2rx1)
HGL: 101722936(P2rx1)
CCAN: 109694318(P2rx1)
OCU: 100350587(P2RX1)
TUP: 102478169(P2RX1)
CFA: 491223(P2RX1)
AML: 100463691(P2RX1)
UMR: 103667126(P2RX1)
ORO: 101384775(P2RX1)
FCA: 101091060(P2RX1)
PTG: 102963241(P2RX1)
AJU: 106987363(P2RX1)
BTA: 514898(P2RX1)
BOM: 102278561(P2RX1)
BIU: 109573594(P2RX1)
PHD: 102314849(P2RX1)
CHX: 102180347(P2RX1)
OAS: 101101902(P2RX1)
SSC: 106504105(P2RX1) 503667(CAMKK1)
CFR: 102513760(P2RX1)
CDK: 105095744(P2RX1)
BACU: 103009121(P2RX1)
LVE: 103075554(P2RX1)
OOR: 101273602(P2RX1)
ECB: 100060689(P2RX1)
EPZ: 103558306(P2RX1)
EAI: 106825737(P2RX1)
MYB: 102239604(P2RX1)
MYD: 102753864(P2RX1)
HAI: 109391888(P2RX1)
RSS: 109453782(P2RX1)
PALE: 102881068(P2RX1)
LAV: 100671204(P2RX1)
TMU: 101354076
MDO: 100031997(P2RX1)
OAA: 100087194(P2RX1)
GGA: 395190(P2RX1)
MGP: 100541424(P2RX1)
CJO: 107322652(P2RX1)
APLA: 101804477(P2RX1)
ACYG: 106041500(P2RX1)
TGU: 100219427(P2RX1)
GFR: 102041318(P2RX1)
FAB: 101815231(P2RX1)
PHI: 102102022(P2RX1)
PMAJ: 107212650(P2RX1)
CCW: 104691126(P2RX1)
FPG: 101924292(P2RX1)
FCH: 102059123(P2RX1)
CLV: 102093190(P2RX1)
EGZ: 104131785(P2RX1)
AAM: 106487819
ASN: 102371579(P2RX1)
AMJ: 102564148(P2RX1)
PSS: 102446259(P2RX1)
CMY: 102946676(P2RX1)
CPIC: 101944607(P2RX1)
PVT: 110075497(P2RX1)
PBI: 103066551(P2RX1)
GJA: 107107675(P2RX1)
XLA: 108708358(p2rx1.L) 108708940(p2rx1.S)
XTR: 100485618(p2rx1)
NPR: 108784527(P2RX1)
DRE: 387296(p2rx1)
SRX: 107712377 107748506(p2rx1)
SANH: 107664412(p2rx1) 107664512
IPU: 108260336(p2rx1)
AMEX: 103022360(p2rx1)
TRU: 101077982(p2rx1)
LCO: 104928779(p2rx1)
NCC: 104961815(p2rx1)
MZE: 101469120(p2rx1)
OLA: 101169631(p2rx1)
XMA: 102233584(p2rx1)
PRET: 103476076(p2rx1)
NFU: 107387027(p2rx1)
CSEM: 103395211(p2rx1)
LCF: 108893661(p2rx1)
HCQ: 109531111(p2rx1)
BPEC: 110165084(p2rx1)
SASA: 106567409(p2rx1) 106603936
ELS: 105025948(p2rx1)
SFM: 108928068(p2rx1)
LCM: 102348549(P2RX1)
CMK: 103172400(p2rx1)
FCD: 110847396
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7523951
  Authors
Valera S, Hussy N, Evans RJ, Adami N, North RA, Surprenant A, Buell G
  Title
A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP.
  Journal
Nature 371:516-9 (1994)
DOI:10.1038/371516a0
  Sequence
[rno:25505]

KEGG   ORTHOLOGY: K05216Help
Entry
K05216                      KO                                     

Name
P2RX2
Definition
P2X purinoceptor 2
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04742  Taste transduction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05216  P2RX2; P2X purinoceptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05216  P2RX2; P2X purinoceptor 2
 09150 Organismal Systems
  09157 Sensory system
   04742 Taste transduction
    K05216  P2RX2; P2X purinoceptor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05216  P2RX2; P2X purinoceptor 2
Ion channels [BR:ko04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05216  P2RX2; P2X purinoceptor 2
BRITE hierarchy
Other DBs
GO: 0001614 0004931
TC: 1.A.7.1.2
Genes
HSA: 22953(P2RX2)
PTR: 100615394(P2RX2)
PPS: 100973505(P2RX2)
GGO: 101124304(P2RX2)
PON: 100455448(P2RX2)
NLE: 100586671(P2RX2)
MCC: 693390(P2RX2)
MCF: 102121756(P2RX2)
CSAB: 103239451(P2RX2)
RRO: 104674327(P2RX2)
RBB: 108544495(P2RX2)
CJC: 100406252(P2RX2)
SBQ: 101028224(P2RX2)
MMU: 231602(P2rx2)
RNO: 114115(P2rx2)
CGE: 100770815(P2rx2)
NGI: 103750602(P2rx2)
HGL: 101719917(P2rx2)
CCAN: 109686266(P2rx2)
OCU: 100356670(P2RX2)
TUP: 102473926(P2RX2)
CFA: 448781(P2RX2)
AML: 100468510(P2RX2)
UMR: 103678891(P2RX2)
ORO: 101370874(P2RX2)
FCA: 751616(P2RX2)
PTG: 102963320(P2RX2)
AJU: 106985892(P2RX2)
BTA: 527499(P2RX2)
BOM: 102275962(P2RX2)
BIU: 109570897(P2RX2)
PHD: 102335445(P2RX2)
CHX: 102171362(P2RX2)
OAS: 101116428(P2RX2)
SSC: 100736581(P2RX2)
CFR: 102509791(P2RX2)
CDK: 105104095(P2RX2)
BACU: 102998993(P2RX2)
LVE: 103075363(P2RX2)
OOR: 101280504(P2RX2)
ECB: 100061704(P2RX2)
EPZ: 103561639(P2RX2)
EAI: 106843862(P2RX2)
MYB: 102242465(P2RX2)
MYD: 102770010(P2RX2)
HAI: 109376154(P2RX2)
RSS: 109443003 109456445(P2RX2)
PALE: 102891282(P2RX2)
LAV: 100654833(P2RX2)
TMU: 101358869
MDO: 100027526(P2RX2)
SHR: 100930241(P2RX2)
OAA: 100080197(P2RX2)
GGA: 101749217(P2RX2)
MGP: 100546669(P2RX2)
CJO: 107321092(P2RX2)
APLA: 101790466(P2RX2)
ACYG: 106047467(P2RX2)
AAM: 106487396(P2RX2)
ASN: 102383977(P2RX2)
AMJ: 102563325(P2RX2)
PSS: 102447498(P2RX2)
CMY: 102936772(P2RX2)
CPIC: 101946583(P2RX2)
ACS: 100553798(p2rx2)
PVT: 110082885(P2RX2)
PBI: 103049513(P2RX2)
GJA: 107122109(P2RX2)
XLA: 108705028 108715297(p2rx2.L)
XTR: 101730278(p2rx2)
NPR: 108786245(P2RX2)
DRE: 387297(p2rx2)
SRX: 107741507(p2rx2)
SANH: 107704555
SGH: 107599138(p2rx2)
IPU: 108255423(p2rx2)
AMEX: 103041467
TRU: 101079700(p2rx2)
LCO: 104921248(p2rx2)
NCC: 104945036(p2rx2)
MZE: 101477055(p2rx2)
OLA: 101171837(p2rx2)
XMA: 102217025(p2rx2)
PRET: 103470348(p2rx2)
NFU: 107393956(p2rx6)
CSEM: 103397305(p2rx2)
LCF: 108878121(p2rx2)
HCQ: 109514090
BPEC: 110156760(p2rx2)
ELS: 105014432
SFM: 108932542(p2rx2)
LCM: 102355205(P2RX2)
CMK: 103184094(p2rx2)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7523952
  Authors
Brake AJ, Wagenbach MJ, Julius D
  Title
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor.
  Journal
Nature 371:519-23 (1994)
DOI:10.1038/371519a0
  Sequence
[rno:114115]

KEGG   ORTHOLOGY: K05217Help
Entry
K05217                      KO                                     

Name
P2RX3
Definition
P2X purinoceptor 3
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04742  Taste transduction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05217  P2RX3; P2X purinoceptor 3
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05217  P2RX3; P2X purinoceptor 3
 09150 Organismal Systems
  09157 Sensory system
   04742 Taste transduction
    K05217  P2RX3; P2X purinoceptor 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05217  P2RX3; P2X purinoceptor 3
Ion channels [BR:ko04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05217  P2RX3; P2X purinoceptor 3
BRITE hierarchy
Other DBs
GO: 0001614 0004931
TC: 1.A.7.1.6
Genes
HSA: 5024(P2RX3)
PTR: 742961(P2RX3)
PPS: 100970270(P2RX3)
GGO: 101127799(P2RX3)
PON: 100433053(P2RX3)
NLE: 100579316(P2RX3)
MCC: 706503(P2RX3)
MCF: 102141471(P2RX3)
CSAB: 103235472(P2RX3)
RRO: 104654292(P2RX3)
RBB: 108514836(P2RX3)
CJC: 100414073(P2RX3)
SBQ: 101044762(P2RX3)
MMU: 228139(P2rx3)
RNO: 81739(P2rx3)
CGE: 100758483(P2rx3)
NGI: 103736625(P2rx3)
HGL: 101709018(P2rx3)
CCAN: 109688996(P2rx3)
OCU: 100348378(P2RX3)
TUP: 102484409(P2RX3)
CFA: 448782(P2RX3)
AML: 100476571(P2RX3)
UMR: 103666110(P2RX3)
ORO: 101362559(P2RX3)
FCA: 751615(P2RX3)
PTG: 102958774(P2RX3)
AJU: 106979540(P2RX3)
BTA: 530468(P2RX3)
BOM: 102281864(P2RX3)
BIU: 109570043(P2RX3)
PHD: 102339075(P2RX3)
CHX: 102180244(P2RX3)
OAS: 101104779(P2RX3)
SSC: 503656(P2RX3)
CFR: 102513517(P2RX3)
CDK: 105101234(P2RX3)
BACU: 103003289(P2RX3)
LVE: 103069544(P2RX3)
OOR: 101278447(P2RX3)
ECB: 100062797(P2RX3)
EPZ: 103562637(P2RX3)
EAI: 106823596(P2RX3)
MYB: 102258212(P2RX3)
MYD: 102763269(P2RX3)
HAI: 109371600(P2RX3)
RSS: 109435479(P2RX3)
PALE: 102884379(P2RX3)
LAV: 100656067(P2RX3)
TMU: 101357425
MDO: 100022565(P2RX3)
SHR: 100929173(P2RX3)
OAA: 100086691(P2RX3)
GGA: 423134(PGR2/3)
MGP: 100538989(P2RX3)
CJO: 107314411(P2RX3)
GFR: 102033509(P2RX3)
FAB: 101805978(P2RX3)
PHI: 102113330(P2RX3)
PMAJ: 107205424(P2RX3)
FPG: 101917477(P2RX3)
FCH: 102053313(P2RX3)
CLV: 102090857(P2RX3)
EGZ: 104123507(P2RX3)
ASN: 102382186(P2RX3)
AMJ: 102572929(P2RX3)
PSS: 102444736(P2RX3)
CMY: 102931043(P2RX3)
CPIC: 101930829(P2RX3)
ACS: 100567834(p2rx3)
PVT: 110078364(P2RX3)
PBI: 103049490(P2RX3)
GJA: 107111159(P2RX3)
NPR: 108797057(P2RX3)
DRE: 387300(p2rx3b) 58147(p2rx3a)
IPU: 108262787(p2rx3) 108268552
TRU: 101065458 101065910(p2rx3)
NCC: 104958121(p2rx3) 104963357
OLA: 101165153 101174325(p2rx3)
XMA: 102218124 102237721(p2rx3)
PRET: 103470816(p2rx3) 103471744
NFU: 107374327(p2rx3) 107374424
ELS: 105022878(p2rx3) 105028897
LCM: 102347407(P2RX3)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9016352
  Authors
Garcia-Guzman M, Soto F, Gomez-Hernandez JM, Lund PE, Stuhmer W
  Title
Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.
  Journal
Mol Pharmacol 51:109-18 (1997)
DOI:10.1124/mol.51.1.109
  Sequence
[hsa:5024]

KEGG   ORTHOLOGY: K05218Help
Entry
K05218                      KO                                     

Name
P2RX4
Definition
P2X purinoceptor 4
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05218  P2RX4; P2X purinoceptor 4
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05218  P2RX4; P2X purinoceptor 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05218  P2RX4; P2X purinoceptor 4
Ion channels [BR:ko04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05218  P2RX4; P2X purinoceptor 4
BRITE hierarchy
Other DBs
GO: 0001614 0004931
TC: 1.A.7.1.4 1.A.7.1.5 1.A.7.3.1
Genes
HSA: 5025(P2RX4)
PTR: 452319(P2RX4)
PPS: 100990374(P2RX4)
GGO: 101148253(P2RX4)
PON: 100458831(P2RX4)
NLE: 100589361(P2RX4)
MCC: 702536(P2RX4)
MCF: 102120732(P2RX4)
CSAB: 103239278(P2RX4)
RRO: 104666272(P2RX4)
RBB: 108529639(P2RX4)
CJC: 100396434(P2RX4)
SBQ: 101046432(P2RX4)
MMU: 18438(P2rx4)
RNO: 29659(P2rx4)
CGE: 100752103(P2rx4)
NGI: 103739074(P2rx4)
HGL: 101723201(P2rx4)
CCAN: 109699537(P2rx4)
OCU: 100008720(P2RX4)
TUP: 102475496(P2RX4)
CFA: 448783(P2RX4)
AML: 100477528(P2RX4)
UMR: 103661274(P2RX4)
ORO: 101366441(P2RX4)
FCA: 101080484(P2RX4)
PTG: 102972163(P2RX4)
AJU: 106967589(P2RX4)
BTA: 338036(P2RX4)
BOM: 102276211(P2RX4)
BIU: 109571456(P2RX4)
PHD: 102341711(P2RX4)
CHX: 102173324(P2RX4)
OAS: 101104013(P2RX4)
SSC: 100157723(P2RX4)
CFR: 102522360(P2RX4)
CDK: 105102503(P2RX4)
BACU: 103001338(P2RX4)
LVE: 103091066(P2RX4)
OOR: 101282492(P2RX4)
ECB: 100059626(P2RX4)
EPZ: 103541695(P2RX4)
EAI: 106842290(P2RX4)
MYB: 102263539(P2RX4)
MYD: 102753054(P2RX4)
HAI: 109386080(P2RX4)
RSS: 109448533(P2RX4)
PALE: 102879399(P2RX4)
LAV: 100670469(P2RX4)
TMU: 111821041
MDO: 100618270(P2RX4)
SHR: 100923139(P2RX4)
OAA: 100090378(P2RX4)
GGA: 374166(P2RX4)
MGP: 100543578(P2RX4)
CJO: 107321119(P2RX4)
APLA: 101791189(P2RX4)
ACYG: 106031149
TGU: 100232437(P2RX4)
GFR: 102039359(P2RX4)
FAB: 101815352(P2RX4)
PHI: 102112929(P2RX4)
PMAJ: 107211610(P2RX4)
CCW: 104688704(P2RX4)
FPG: 101919147(P2RX4)
FCH: 102054376(P2RX4)
CLV: 102085962(P2RX4)
EGZ: 104130145(P2RX4)
AAM: 106497654(P2RX4)
ASN: 102376745(P2RX4)
AMJ: 102564687(P2RX4)
PSS: 102443940(P2RX4)
CMY: 102931602(P2RX4)
CPIC: 101943499(P2RX4)
ACS: 100561452(p2rx4)
PVT: 110083823(P2RX4)
PBI: 103057916(P2RX4)
GJA: 107115912(P2RX4)
XLA: 398206(p2rx4.L)
XTR: 100489363(p2rx4)
NPR: 108787253(P2RX4)
DRE: 259258(p2rx4a) 387301(p2rx4b)
IPU: 108279151(p2rx4)
AMEX: 103024165(p2rx4)
TRU: 101070550(p2rx4)
LCO: 104926383(p2rx4)
NCC: 104965470
MZE: 101483332(p2rx4)
OLA: 101168548(p2rx4)
XMA: 102232033
PRET: 103469516
NFU: 107393858
LCF: 108878573(p2rx4)
BPEC: 110163349
SASA: 100195175(p2rx4) 106579965
SFM: 108921859 108933374(p2rx4)
LCM: 102346773(P2RX4)
CMK: 103184313(p2rx4)
SKO: 100313714
CRG: 105318736
MYI: 110465852
OBI: 106876052
ADF: 107358498
HMG: 100211566
AQU: 100636400
SMIN: v1.2.024239.t1(symbB.v1.2.024239.t1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9016352
  Authors
Garcia-Guzman M, Soto F, Gomez-Hernandez JM, Lund PE, Stuhmer W
  Title
Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.
  Journal
Mol Pharmacol 51:109-18 (1997)
DOI:10.1124/mol.51.1.109
  Sequence
[hsa:5025]

KEGG   ORTHOLOGY: K05219Help
Entry
K05219                      KO                                     

Name
P2RX5
Definition
P2X purinoceptor 5
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05219  P2RX5; P2X purinoceptor 5
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05219  P2RX5; P2X purinoceptor 5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05219  P2RX5; P2X purinoceptor 5
Ion channels [BR:ko04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05219  P2RX5; P2X purinoceptor 5
BRITE hierarchy
Other DBs
GO: 0001614 0004931
TC: 1.A.7.1
Genes
HSA: 5026(P2RX5)
PTR: 454434(P2RX5)
PPS: 100987979(P2RX5)
GGO: 101151906(P2RX5)
PON: 100449349(P2RX5)
NLE: 100594071(P2RX5)
MCC: 721476(P2RX5)
MCF: 102142153(P2RX5)
CSAB: 103242166(P2RX5)
RRO: 104677252(P2RX5)
RBB: 108523100(P2RX5)
CJC: 100411168(P2RX5)
SBQ: 101035805(P2RX5)
MMU: 94045(P2rx5)
RNO: 113995(P2rx5)
CGE: 100772284(P2rx5)
NGI: 103752018(P2rx5)
HGL: 101725587(P2rx5)
CCAN: 109694457(P2rx5)
OCU: 100355479(P2RX5)
TUP: 102500710(P2RX5)
CFA: 448785(P2RX5)
AML: 100464947(P2RX5)
UMR: 103667128(P2RX5)
ORO: 101362420(P2RX5)
FCA: 101080493(P2RX5)
PTG: 102961352(P2RX5)
AJU: 106987360(P2RX5)
BTA: 338035(P2RX5)
BOM: 102288136(P2RX5)
BIU: 109573593(P2RX5)
PHD: 102344393(P2RX5)
CHX: 102179517(P2RX5)
OAS: 101110429(P2RX5)
SSC: 100519563(P2RX5)
CFR: 102517645(P2RX5)
CDK: 105095750(P2RX5)
BACU: 103011151(P2RX5)
LVE: 103074692(P2RX5)
OOR: 101273843(P2RX5)
EPZ: 103562926(P2RX5)
EAI: 106825658(P2RX5)
MYB: 102261486(P2RX5)
MYD: 102754625(P2RX5)
HAI: 109391881(P2RX5)
RSS: 109453781(P2RX5)
PALE: 102879785(P2RX5)
LAV: 100674260(P2RX5)
TMU: 101344030
MDO: 100022424
SHR: 100923604(P2RX5)
OAA: 100077854(P2RX5)
GGA: 395507(P2RX5)
MGP: 100548411(P2RX5)
CJO: 107322399(P2RX5)
APLA: 101797369(P2RX5)
ACYG: 106045782(P2RX5)
TGU: 100226199(P2RX5)
GFR: 102040218(P2RX5)
FAB: 101821279(P2RX5)
PHI: 102105994(P2RX5)
PMAJ: 107212709(P2RX5)
CCW: 104691032(P2RX5)
FPG: 101911936(P2RX5)
FCH: 102046370(P2RX5)
CLV: 102098338(P2RX5)
EGZ: 104121904(P2RX5)
AAM: 106493765(P2RX5)
ASN: 102387044(P2RX5)
AMJ: 102563213(P2RX5)
PSS: 102446429(P2RX5)
CMY: 102934766(P2RX5)
CPIC: 101945661(P2RX5)
PVT: 110087400(P2RX5)
PBI: 103065205
GJA: 107106701(P2RX5)
XLA: 108707930(p2rx5.L) 108709191(p2rx5.S)
XTR: 100485445(p2rx5)
NPR: 108787949(P2RX5)
DRE: 373879(p2rx5) 387299(p2rx8)
AMEX: 103033181 103034935(p2rx5)
TRU: 101068098(p2rx5)
LCO: 104923438(p2rx5) 104940528
NCC: 104949202 104963936(p2rx5)
MZE: 101471200(p2rx5) 101482192
OLA: 101173001
XMA: 102235465(p2rx5)
PRET: 103476041(p2rx5)
NFU: 107387066(p2rx5)
CSEM: 103377655 103394904(p2rx5)
LCF: 108894004(p2rx5) 108898797
HCQ: 109526227 109531110(p2rx5)
SASA: 106567984(p2rx5) 106603501
ELS: 105030979(p2rx5)
LCM: 102361591(P2RX5)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9414125
  Authors
Le KT, Paquet M, Nouel D, Babinski K, Seguela P
  Title
Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system.
  Journal
FEBS Lett 418:195-9 (1997)
DOI:10.1016/S0014-5793(97)01380-X
  Sequence
[hsa:5026]

KEGG   ORTHOLOGY: K05220Help
Entry
K05220                      KO                                     

Name
P2RX7
Definition
P2X purinoceptor 7
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04621  NOD-like receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05220  P2RX7; P2X purinoceptor 7
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05220  P2RX7; P2X purinoceptor 7
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K05220  P2RX7; P2X purinoceptor 7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05220  P2RX7; P2X purinoceptor 7
Ion channels [BR:ko04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05220  P2RX7; P2X purinoceptor 7
BRITE hierarchy
Other DBs
GO: 0001614 0004931
TC: 1.A.7.1.3
Genes
HSA: 5027(P2RX7)
PTR: 452318(P2RX7)
PPS: 100990943(P2RX7)
GGO: 101146233(P2RX7)
PON: 100450613(P2RX7)
NLE: 100588362(P2RX7)
MCC: 699455(P2RX7)
MCF: 101865374(P2RX7)
CSAB: 103239277(P2RX7)
RRO: 104666270(P2RX7)
RBB: 108529640(P2RX7)
CJC: 100393329(P2RX7)
SBQ: 101046955(P2RX7)
MMU: 18439(P2rx7)
RNO: 29665(P2rx7)
CGE: 100765617(P2rx7)
NGI: 103739075(P2rx7)
HGL: 101721795(P2rx7)
CCAN: 109679346(P2rx7) 109701526
OCU: 100351535(P2RX7)
TUP: 102495976(P2RX7)
CFA: 448778(P2RX7)
AML: 100477277(P2RX7)
UMR: 103661168(P2RX7)
ORO: 101366160(P2RX7)
FCA: 101097922(P2RX7)
PTG: 102949692(P2RX7)
AJU: 106967541(P2RX7)
BTA: 286814(P2RX7)
BOM: 102282196
BIU: 109571559(P2RX7)
PHD: 102341350(P2RX7)
CHX: 102174145(P2RX7)
OAS: 101103842(P2RX7)
SSC: 497623(P2RX7)
CFR: 102505603(P2RX7)
CDK: 105102501(P2RX7)
BACU: 102999858(P2RX7)
LVE: 103091614(P2RX7)
OOR: 101283001(P2RX7)
ECB: 100058464(P2RX7)
EPZ: 103541440(P2RX7)
EAI: 106842288(P2RX7)
MYD: 102751346(P2RX7)
HAI: 109386041(P2RX7)
RSS: 109448531(P2RX7)
PALE: 102879645(P2RX7)
LAV: 100677782(P2RX7)
MDO: 100020874
SHR: 100922617
GGA: 771952(P2RX7)
MGP: 100543425(P2RX7)
CJO: 107321117(P2RX7)
APLA: 101801281(P2RX7)
ACYG: 106031147
FPG: 101919310(P2RX7)
FCH: 102054201(P2RX7)
EGZ: 104130146(P2RX7)
AAM: 106497670
ASN: 102380463(P2RX7)
AMJ: 102564452(P2RX7)
PSS: 102462065(P2RX7)
CMY: 102932507(P2RX7)
CPIC: 101943226(P2RX7)
ACS: 100561255(p2rx7)
PVT: 110083862(P2RX7)
PBI: 103058161(P2RX7)
GJA: 107115894(P2RX7)
XLA: 398286(p2rx7.L)
XTR: 100490662(p2rx7) 100490828
NPR: 108787232 108787241(P2RX7)
DRE: 387298(p2rx7)
SANH: 107667522
CCAR: 109105006
TRU: 101079170(p2rx7)
LCO: 104934856(p2rx7)
MZE: 101482732(p2rx7)
XMA: 102233539
PRET: 103470699(p2rx7)
NFU: 107386088(p2rx7)
LCF: 108881637
HCQ: 109515577
BPEC: 110170698(p2rx7)
SASA: 106579964
ELS: 109614602
SFM: 108921860
LCM: 102352362(P2RX7)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cheewatrakoolpong B, Gilchrest H, Anthes JC, Greenfeder S
  Title
Identification and characterization of splice variants of the human P2X7 ATP channel.
  Journal
Biochem Biophys Res Commun 332:17-27 (2005)
DOI:10.1016/j.bbrc.2005.04.087
  Sequence
[hsa:5027]

KEGG   ORTHOLOGY: K05221Help
Entry
K05221                      KO                                     

Name
P2RX6, P2RXL1
Definition
P2X purinoceptor 6
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05221  P2RX6, P2RXL1; P2X purinoceptor 6
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05221  P2RX6, P2RXL1; P2X purinoceptor 6
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05221  P2RX6, P2RXL1; P2X purinoceptor 6
Ion channels [BR:ko04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05221  P2RX6, P2RXL1; P2X purinoceptor 6
BRITE hierarchy
Other DBs
GO: 0001614 0004931
TC: 1.A.7.1
Genes
HSA: 9127(P2RX6)
PTR: 745626(P2RX6)
PPS: 100976042(P2RX6)
GGO: 101125348(P2RX6) 101128851
PON: 100445728(P2RX6)
NLE: 100588488(P2RX6)
MCC: 695841(P2RX6)
MCF: 102129289(P2RX6)
CSAB: 103223600
RRO: 104666856(P2RX6)
RBB: 108536090(P2RX6)
CJC: 100397824(P2RX6)
SBQ: 101053195
MMU: 18440(P2rx6)
RNO: 25041(P2rx6)
CGE: 100757216(P2rx6)
NGI: 103741467(P2rx6)
HGL: 101702346(P2rx6)
CCAN: 109684367(P2rx6)
OCU: 100349719(P2RX6)
TUP: 102480592(P2RX6)
CFA: 486436(P2RX6)
AML: 100471072(P2RX6)
UMR: 103669295(P2RX6)
ORO: 101384051(P2RX6)
FCA: 101083550(P2RX6) 105259651
PTG: 102951525(P2RX6)
AJU: 106983636(P2RX6) 106989856
BTA: 618262(P2RX6)
BOM: 102280240(P2RX6)
BIU: 109571268(P2RX6)
PHD: 102318079(P2RX6)
CHX: 102173383(P2RX6)
OAS: 101118819(P2RX6)
SSC: 100515342(P2RX6)
CFR: 102514060(P2RX6)
CDK: 105095226(P2RX6)
BACU: 103018925(P2RX6)
LVE: 103079189(P2RX6)
OOR: 101287569(P2RX6)
ECB: 100051842(P2RX6)
MYB: 102250561(P2RX6)
MYD: 102760075(P2RX6)
HAI: 109376246(P2RX6)
RSS: 109461467(P2RX6)
PALE: 102894381(P2RX6)
LAV: 100661194(P2RX6)
TMU: 101350747
SHR: 105749675(P2RX6)
OAA: 100084240(P2RX6)
GGA: 429367(P2RX6)
MGP: 100547282(P2RX6)
CJO: 107321406(P2RX6)
APLA: 101790078(P2RX6)
ACYG: 106047463(P2RX6)
TGU: 100217680(P2RX6)
GFR: 102044532(P2RX6)
FAB: 101811989(P2RX6)
PHI: 102100542(P2RX6)
PMAJ: 107211738(P2RX6)
CCW: 104695019
FPG: 101912387(P2RX6)
FCH: 102056684(P2RX6)
CLV: 102087218(P2RX6)
EGZ: 104129951(P2RX6)
AAM: 106494506(P2RX6)
ACS: 100555164(p2rx6)
PVT: 110081946(P2RX6)
PBI: 103054093(P2RX6)
GJA: 107126087(P2RX6)
XTR: 105948055(p2rx6)
NPR: 108800508
LCM: 102346368
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9242461
  Authors
Urano T, Nishimori H, Han H, Furuhata T, Kimura Y, Nakamura Y, Tokino T
  Title
Cloning of P2XM, a novel human P2X receptor gene regulated by p53.
  Journal
Cancer Res 57:3281-7 (1997)
  Sequence
[hsa:9127]

KEGG   ORTHOLOGY: K04809Help
Entry
K04809                      KO                                     

Name
CHRNA7
Definition
nicotinic acetylcholine receptor alpha-7
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04725  Cholinergic synapse
ko05033  Nicotine addiction
ko05204  Chemical carcinogenesis
Disease
H01877  Chromosome 15q13.3 microdeletion syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
 09160 Human Diseases
  09161 Cancers
   05204 Chemical carcinogenesis
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
  09164 Substance dependence
   05033 Nicotine addiction
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
Ion channels [BR:ko04040]
 Ligand-gated channels
  Acetylcholine (nicotinic)
   K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
BRITE hierarchy
Other DBs
GO: 0004889 0015464
TC: 1.A.9.1
Genes
HSA: 1139(CHRNA7)
PTR: 467639(CHRNA7)
PPS: 100977072(CHRNA7)
GGO: 101131793(CHRNA7) 101153572
PON: 100456533(CHRNA7)
NLE: 100588609
MCC: 574230(CHRNA7)
MCF: 102118754(CHRNA7)
CSAB: 103245932(CHRNA7)
RRO: 104668890(CHRNA7)
RBB: 108531792(CHRNA7)
CJC: 100385253(CHRNA7)
SBQ: 101050618(CHRNA7)
MMU: 11441(Chrna7)
RNO: 25302(Chrna7)
CGE: 100760319
NGI: 103748066
HGL: 101720562(Chrna7)
CCAN: 109674332
OCU: 100342986(CHRNA7)
TUP: 102493539(CHRNA7)
CFA: 488696(CHRNA7)
AML: 100469287(CHRNA7)
UMR: 103659968(CHRNA7)
ORO: 101363826(CHRNA7)
FCA: 751113(CHRNA7)
PTG: 102955772(CHRNA7)
AJU: 106967817
BTA: 282178(CHRNA7)
BOM: 102272741(CHRNA7)
BIU: 109575699(CHRNA7)
PHD: 102319820
CHX: 102179705(CHRNA7)
OAS: 101113104(CHRNA7)
SSC: 100415931(CHRNA7)
CFR: 102524002(CHRNA7)
CDK: 105104257
BACU: 103019913
LVE: 103084703
OOR: 101280887(CHRNA7)
ECB: 100060521
EPZ: 103562081
EAI: 106834056(CHRNA7)
MYB: 102246452(CHRNA7)
MYD: 102764475(CHRNA7)
HAI: 109372169
RSS: 109459063(CHRNA7)
PALE: 102889630
LAV: 100656157
TMU: 101347897
MDO: 100027128
SHR: 100930913(CHRNA7)
OAA: 100087588
GGA: 374001(CHRNA7) 396120(CHRNA7L)
MGP: 100543989(CHRNA7)
CJO: 107306401 107318653(CHRNA7)
APLA: 101793841 101795859(CHRNA7)
TGU: 100221863 100228395(CHRNA7)
FAB: 101815421(CHRNA7) 101818819
PHI: 102107326 102109591(CHRNA7)
PMAJ: 107198461 107209183(CHRFAM7A)
CCW: 104684036(CHRFAM7A) 104689759 109143409
FPG: 101911506(CHRNA7) 101922648
FCH: 102054617(CHRNA7) 102054706
CLV: 102095407 102098551(CHRFAM7A)
EGZ: 104124489 104130764(CHRFAM7A)
AAM: 106496424(CHRNA7)
ASN: 102371460 102376107(CHRNA7)
AMJ: 102561740 102565383(CHRNA7)
CPIC: 101936924 101950931(CHRNA7)
PVT: 110074548(CHRFAM7A) 110081449 110083158
XLA: 108706777 108711357(chrna7.L) 108712944(chrna7.S) 108719663
XTR: 100487782 100493611(chrna7)
NPR: 108788185 108793324(CHRNA7)
DRE: 100537531(si:ch73-380n15.2) 394199(chrna7) 566141(si:ch211-39a7.1)
TRU: 446018(a7b) 446024(Fr_a8a) 446091(Fr_a8b)
LCM: 102362835 102366146(CHRNA7)
CMK: 103177743 103187814(chrna7)
FCD: 110842068
CRG: 105334519
MYI: 110452062
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8145738
  Authors
Peng X, Katz M, Gerzanich V, Anand R, Lindstrom J
  Title
Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.
  Journal
Mol Pharmacol 45:546-54 (1994)
  Sequence
[hsa:1139]
Reference
  Authors
Papke RL, Horenstein NA, Kulkarni AR, Stokes C, Corrie LW, Maeng CY, Thakur GA
  Title
The activity of GAT107, an allosteric activator and positive modulator of alpha7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.
  Journal
J Biol Chem 289:4515-31 (2014)
DOI:10.1074/jbc.M113.524603

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