KEGG   ORTHOLOGY: K05251Help
Entry
K05251                      KO                                     

Name
TSHB
Definition
thyroid stimulating hormone, beta
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04918  Thyroid hormone synthesis
ko04923  Regulation of lipolysis in adipocytes
ko05320  Autoimmune thyroid disease
Disease
H00250  Congenital nongoitrous hypothyroidism (CHNG)
H01699  Isolated TSH deficiency
H01700  Hypopituitarism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05251  TSHB; thyroid stimulating hormone, beta
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K05251  TSHB; thyroid stimulating hormone, beta
   04918 Thyroid hormone synthesis
    K05251  TSHB; thyroid stimulating hormone, beta
 09160 Human Diseases
  09162 Immune diseases
   05320 Autoimmune thyroid disease
    K05251  TSHB; thyroid stimulating hormone, beta
BRITE hierarchy
Genes
HSA: 7252(TSHB)
PTR: 748248(TSHB)
PPS: 100967932(TSHB)
GGO: 101149441(TSHB)
PON: 100443696(TSHB)
NLE: 100593224(TSHB)
MCC: 709374(TSHB)
MCF: 102135350(TSHB)
CSAB: 103224162(TSHB)
RRO: 104669072(TSHB)
RBB: 108528124(TSHB)
CJC: 100385359(TSHB)
SBQ: 101038043(TSHB)
MMU: 22094(Tshb)
RNO: 25653(Tshb)
CGE: 100751072(Tshb)
NGI: 103734942(Tshb)
HGL: 101720907(Tshb)
CCAN: 109682241(Tshb)
OCU: 100302414(TSHB)
TUP: 102501103(TSHB)
CFA: 403973(TSHB)
AML: 100469951(TSHB)
UMR: 103669418(TSHB)
ORO: 101385992(TSHB)
FCA: 554350(TSHB)
PTG: 102951543(TSHB)
AJU: 106969661(TSHB)
BTA: 281552(TSHB)
BOM: 102287977(TSHB)
BIU: 109555886(TSHB)
PHD: 102343915(TSHB)
CHX: 102185966(TSHB)
OAS: 101104284(TSHB)
SSC: 397658(TSHB)
CFR: 102511444(TSHB)
CDK: 105089625(TSHB)
BACU: 103002421(TSHB)
LVE: 103084958(TSHB)
OOR: 101277384(TSHB)
ECB: 100034188(TSHB)
EPZ: 103547739(TSHB)
EAI: 106835710(TSHB)
MYB: 102247015(TSHB)
MYD: 102761777(TSHB)
HAI: 109392811(TSHB)
RSS: 109446782(TSHB)
PALE: 102887106(TSHB)
LAV: 100660279(TSHB)
TMU: 101342176
MDO: 503501(TSHB)
SHR: 100927019(TSHB)
OAA: 100074530(TSHB)
GGA: 395937(TSHB)
MGP: 100546526(TSHB)
CJO: 107324819(TSHB)
APLA: 101804542(TSHB)
ACYG: 106041291(TSHB)
TGU: 100220136(TSHB)
GFR: 102040289(TSHB)
FAB: 101818412(TSHB)
PHI: 102111041(TSHB)
PMAJ: 107214721(TSHB)
CCW: 104692414(TSHB)
FPG: 101920577(TSHB)
FCH: 102055291(TSHB)
CLV: 102098073(TSHB)
EGZ: 104126777(TSHB)
AAM: 106485256(TSHB)
ASN: 102380596(TSHB)
AMJ: 102568447(TSHB)
PSS: 102449915(TSHB)
CMY: 102944542(TSHB)
CPIC: 101951522(TSHB)
ACS: 100552987(tshb)
PVT: 110072381(TSHB)
PBI: 103057906(TSHB)
GJA: 107111993(TSHB)
XLA: 100381085(tshb.S) 108707690(tshb.L)
XTR: 100496349(tshb)
NPR: 108799084(TSHB)
DRE: 353223(tshba)
IPU: 108271948
AMEX: 103029304
TRU: 101067051(tshb) 101071898(fshb)
LCO: 104918371(tshb) 104933253
MZE: 101469720
NFU: 107385053
CSEM: 103386559
HCQ: 109506967
BPEC: 110164942
SASA: 100136355(tshb) 106572976
ELS: 105007569
SFM: 108918388(tshb) 108939147
LCM: 102362870 102363810(TSHB)
CMK: 103179889 103183879(tshb)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1320763
  Authors
Dumont JE, Lamy F, Roger P, Maenhaut C
  Title
Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors.
  Journal
Physiol Rev 72:667-97 (1992)

KEGG   ORTHOLOGY: K08522Help
Entry
K08522                      KO                                     

Name
CGA
Definition
glycoprotein hormones, alpha polypeptide
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04912  GnRH signaling pathway
ko04913  Ovarian steroidogenesis
ko04917  Prolactin signaling pathway
ko04918  Thyroid hormone synthesis
ko04923  Regulation of lipolysis in adipocytes
ko05320  Autoimmune thyroid disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K08522  CGA; glycoprotein hormones, alpha polypeptide
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04912 GnRH signaling pathway
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04913 Ovarian Steroidogenesis
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04917 Prolactin signaling pathway
    K08522  CGA; glycoprotein hormones, alpha polypeptide
   04918 Thyroid hormone synthesis
    K08522  CGA; glycoprotein hormones, alpha polypeptide
 09160 Human Diseases
  09162 Immune diseases
   05320 Autoimmune thyroid disease
    K08522  CGA; glycoprotein hormones, alpha polypeptide
BRITE hierarchy
Genes
HSA: 1081(CGA)
PTR: 462868(CGA)
PPS: 100987945(CGA)
GGO: 101123865(CGA)
PON: 100462106(CGA)
NLE: 100582786(CGA)
MCC: 697859(CGA)
MCF: 102138376(CGA)
CSAB: 103240056(CGA)
RRO: 104681605(CGA)
RBB: 108538506(CGA)
CJC: 100389264(CGA)
SBQ: 101032263(CGA)
MMU: 12640(Cga)
RNO: 116700(Cga)
CGE: 100689452(Cga)
NGI: 103729473(Cga)
HGL: 101704979(Cga)
CCAN: 109675369(Cga)
OCU: 100009481(CGA)
TUP: 102467691(CGA)
CFA: 403483(CGA)
AML: 100480190(CGA)
UMR: 103659748(CGA)
ORO: 101375408(CGA)
FCA: 751819(CGA)
PTG: 102954911(CGA)
AJU: 106972533(CGA)
BTA: 280749(CGA)
BOM: 102279387(CGA)
BIU: 109563646(CGA)
PHD: 102334639(CGA)
CHX: 100860817(CGA) 102181038(CGA)
OAS: 443538(CGA)
SSC: 406869(CGA)
CFR: 102519852(CGA)
CDK: 105095553(CGA)
BACU: 103006767(CGA)
LVE: 103072990(CGA)
OOR: 101271158(CGA)
ECB: 100034174(CGA)
EPZ: 103547763(CGA)
EAI: 106835849(CGA)
MYB: 102239335(CGA)
MYD: 102769451(CGA)
RSS: 109453489(CGA)
PALE: 102890788(CGA)
LAV: 100673911(CGA)
TMU: 101345506
MDO: 554198(CGA)
SHR: 100915093(CGA)
OAA: 100082555(CGA)
GGA: 421829(CGA)
MGP: 100303682(CGA)
CJO: 107311949(CGA)
APLA: 101793145(CGA)
ACYG: 106035416(CGA)
TGU: 100227314(CGA)
GFR: 102039413(CGA)
FAB: 101808078(CGA)
PHI: 102102480(CGA)
PMAJ: 107201389(CGA)
CCW: 104692463(CGA)
FPG: 101920944(CGA)
FCH: 102047327(CGA)
CLV: 102090935(CGA)
EGZ: 104135351(CGA)
AAM: 106489639(CGA)
ASN: 102369642(CGA)
AMJ: 102563579(CGA)
PSS: 102457567(CGA)
CMY: 102931360(CGA)
CPIC: 101931903(CGA)
ACS: 100557664(cga)
PVT: 110077363(CGA)
PBI: 103061936(CGA)
GJA: 107121763(CGA)
XLA: 378681(cga.S) 432256(cga.L)
XTR: 100488153(cga)
NPR: 108785310(CGA)
DRE: 402987(cga)
SANH: 107672353(cga)
SGH: 107573322(cga)
CCAR: 109081150(cga)
IPU: 100304479(cga)
AMEX: 103028076(cga)
TRU: 101075135(cga)
LCO: 104922151(cga)
NCC: 104945545(cga)
MZE: 101464445(cga)
OLA: 100144350(cga)
XMA: 102222175(cga)
PRET: 103458809(cga)
NFU: 107392255(cga)
CSEM: 103378053(cga)
LCF: 108874911(cga)
HCQ: 109507742(cga)
SASA: 100136440(glha2) 100286517(glha1) 106610036 106610688
ELS: 105016032(cga)
SFM: 108922770(cga)
LCM: 102359455(CGA)
CMK: 103178889(cga)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Aussedat B, Fasching B, Johnston E, Sane N, Nagorny P, Danishefsky SJ
  Title
Total synthesis of the alpha-subunit of human glycoprotein hormones: toward fully synthetic homogeneous human follicle-stimulating hormone.
  Journal
J Am Chem Soc 134:3532-41 (2012)
DOI:10.1021/ja2111459

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