KEGG   ORTHOLOGY: K05611Help
Entry
K05611                      KO                                     

Name
UCHL1
Definition
ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
Pathway
ko05012  Parkinson disease
Disease
H00057  Parkinson disease (PD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05012 Parkinson disease
    K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases
    K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C12: ubiquitin C-terminal hydrolase family
   K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
Ubiquitin system [BR:ko04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UCH
    K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
BRITE hierarchy
Other DBs
GO: 0004843
Genes
HSA: 7345(UCHL1)
PTR: 461185(UCHL1)
PPS: 100978798(UCHL1)
GGO: 101150793(UCHL1)
PON: 100440914(UCHL1)
NLE: 100588568(UCHL1)
MCC: 701579(UCHL1)
MCF: 102133043(UCHL1)
CSAB: 103246177(UCHL1)
RRO: 104679224(UCHL1)
RBB: 108516888(UCHL1)
CJC: 100409098(UCHL1)
SBQ: 101052104(UCHL1)
MMU: 22223(Uchl1)
RNO: 29545(Uchl1)
CGE: 100766373(Uchl1)
NGI: 103729235(Uchl1)
HGL: 101702892(Uchl1)
CCAN: 109690785(Uchl1)
OCU: 100357806(UCHL1)
TUP: 102478017(UCHL1)
CFA: 479098(UCHL1)
AML: 100484886(UCHL1)
UMR: 103672780(UCHL1)
ORO: 101379197(UCHL1)
FCA: 101093604(UCHL1)
PTG: 102949487(UCHL1)
AJU: 106977844(UCHL1)
BTA: 514394(UCHL1)
BOM: 102282378(UCHL1)
BIU: 109560420(UCHL1)
PHD: 102325635(UCHL1)
CHX: 102178714(UCHL1)
OAS: 101117250(UCHL1)
SSC: 396637(UCHL1)
CFR: 102514352(UCHL1)
CDK: 105089356(UCHL1)
BACU: 103007566(UCHL1)
LVE: 103069363(UCHL1)
OOR: 101283487(UCHL1)
ECB: 100033838(UCHL1)
EPZ: 103566718(UCHL1)
EAI: 106841278(UCHL1)
MYB: 102262310(UCHL1)
MYD: 102769091(UCHL1)
HAI: 109381761(UCHL1)
RSS: 109458385(UCHL1)
PALE: 102881932(UCHL1)
LAV: 100662483(UCHL1)
TMU: 101353430
MDO: 100015629(UCHL1)
SHR: 100918150(UCHL1)
GGA: 770302(UCHL1)
MGP: 100549618(UCHL1)
CJO: 107313792(UCHL1)
APLA: 101799480(UCHL1)
ACYG: 106048055(UCHL1)
TGU: 751589(UCHL1)
GFR: 102037972(UCHL1)
FAB: 101809666(UCHL1)
PHI: 102104928(UCHL1)
PMAJ: 107202745(UCHL1)
CCW: 104690880(UCHL1)
FPG: 101924718(UCHL1)
FCH: 102047483(UCHL1)
CLV: 102083724(UCHL1)
EGZ: 104128491(UCHL1)
AAM: 106490166(UCHL1)
ASN: 102372366(UCHL1)
AMJ: 102576186(UCHL1)
PSS: 102451446(UCHL1)
CMY: 102945907(UCHL1)
CPIC: 101941582(UCHL1) 101944408
ACS: 100561831(uchl1)
PVT: 110075251(UCHL1)
PBI: 103058291(UCHL1)
GJA: 107118479(UCHL1)
XLA: 108698136 735204(uchl1.L)
XTR: 496780(uchl1)
NPR: 108790863 108793718(UCHL1)
DRE: 325119(uchl1)
SANH: 107701450 107702299(uchl1)
IPU: 108260831(uchl1)
AMEX: 103023920(uchl1)
TRU: 101069774(uchl1)
LCO: 104934202(uchl1)
NCC: 104942986(uchl1)
MZE: 101482896(uchl1)
OLA: 101155828(uchl1)
XMA: 102233947(uchl1)
PRET: 103459450(uchl1)
NFU: 107395703
CSEM: 103383638(uchl1)
LCF: 108893111(uchl1)
HCQ: 109511321(uchl1)
BPEC: 110167608(uchl1)
SASA: 100196868(uchl1)
ELS: 105007816(uchl1)
SFM: 108924328(uchl1) 108930794
LCM: 102365585(UCHL1)
CMK: 103175870(uchl1)
CPV: cgd8_3200
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury PT Jr
  Title
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
  Journal
Cell 111:209-18 (2002)
DOI:10.1016/S0092-8674(02)01012-7
  Sequence
[hsa:7345]

DBGET integrated database retrieval system