KEGG   ORTHOLOGY: K05688Help
Entry
K05688                      KO                                     

Name
PINK1
Definition
PTEN induced putative kinase 1 [EC:2.7.11.1]
Pathway
ko04137  Mitophagy - animal
ko05012  Parkinson disease
Disease
H00057  Parkinson disease (PD)
H01600  Parkinsonian syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K05688  PINK1; PTEN induced putative kinase 1
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05012 Parkinson disease
    K05688  PINK1; PTEN induced putative kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05688  PINK1; PTEN induced putative kinase 1
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05688  PINK1; PTEN induced putative kinase 1
   03029 Mitochondrial biogenesis
    K05688  PINK1; PTEN induced putative kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05688  PINK1; PTEN induced putative kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  NKF2 family
   K05688  PINK1; PTEN induced putative kinase 1
Membrane trafficking [BR:ko04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    K05688  PINK1; PTEN induced putative kinase 1
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    K05688  PINK1; PTEN induced putative kinase 1
BRITE hierarchy
Genes
HSA: 65018(PINK1)
PTR: 749028(PINK1)
PPS: 100991148(PINK1)
GGO: 101125489(PINK1)
PON: 100443445(PINK1)
NLE: 100599956(PINK1) 105740041
MCC: 698013 706037(PINK1)
MCF: 102125675(PINK1)
CSAB: 103225450(PINK1)
RRO: 104663205(PINK1)
RBB: 108515300(PINK1)
CJC: 100412264(PINK1)
SBQ: 101037834(PINK1)
MMU: 68943(Pink1)
RNO: 298575(Pink1)
CGE: 100757303(Pink1)
NGI: 103738564(Pink1)
HGL: 101716045(Pink1)
CCAN: 109689686(Pink1)
OCU: 100350666(PINK1)
TUP: 102494988(PINK1)
CFA: 100688445(PINK1)
AML: 100465867(PINK1)
UMR: 103666590(PINK1)
ORO: 101381501(PINK1)
FCA: 101093033(PINK1)
PTG: 102955123(PINK1)
AJU: 106987997(PINK1)
BTA: 510683(PINK1)
BOM: 102277915(PINK1)
BIU: 109576174(PINK1)
PHD: 102318826(PINK1)
CHX: 102190832(PINK1)
OAS: 101102131(PINK1)
SSC: 100515613(PINK1)
CFR: 102521586(PINK1)
CDK: 105088855(PINK1)
BACU: 103003466(PINK1)
LVE: 103070110(PINK1)
OOR: 101287390(PINK1)
ECB: 100071784(PINK1)
EPZ: 103541347(PINK1)
EAI: 106840050(PINK1)
MYB: 102242404(PINK1)
MYD: 102757961(PINK1)
HAI: 109395562(PINK1)
RSS: 109434735(PINK1)
PALE: 102889368(PINK1)
LAV: 100671477(PINK1)
TMU: 101344541
MDO: 100027082(PINK1)
SHR: 100928885(PINK1)
OAA: 100089816
MGP: 100540660(PINK1)
CJO: 107323259(PINK1)
APLA: 101789396(PINK1)
ACYG: 106040125(PINK1)
TGU: 100229816(PINK1)
GFR: 102038690(PINK1)
FAB: 101822075(PINK1)
PHI: 102103989(PINK1)
PMAJ: 107213518(PINK1)
CCW: 104697553(PINK1)
FPG: 101915366(PINK1)
FCH: 102053946(PINK1)
CLV: 102093865(PINK1)
EGZ: 104133158(PINK1)
AAM: 106493427(PINK1)
ASN: 106723111(PINK1)
AMJ: 102574908(PINK1)
PSS: 102444248(PINK1)
CMY: 102939538(PINK1)
CPIC: 101943102(PINK1)
PVT: 110072691(PINK1)
PBI: 103059482(PINK1)
GJA: 107124402(PINK1)
DRE: 494085(pink1)
IPU: 108275846(pink1)
AMEX: 103044294(pink1)
TRU: 101064886(pink1)
LCO: 104937209(pink1)
MZE: 101472469(pink1)
OLA: 101159103(pink1)
XMA: 102234169(pink1)
PRET: 103467817(pink1)
NFU: 107390418(pink1)
CSEM: 103385276(pink1)
LCF: 108888646 108888944(pink1)
BPEC: 110159396(pink1)
SASA: 106572550(pink1)
ELS: 105028694(pink1)
SFM: 108939374(pink1)
LCM: 102358303(PINK1)
CMK: 103187676(pink1)
SPU: 100893139
APLC: 110979101
SKO: 102809770
DSI: Dsimw501_GD24757(Dsim_GD24757)
DMO: Dmoj_GI21816(Dmoj_Tes31)
MDE: 101900190
AAG: 5575049
AME: 550929
BIM: 100745293
BTER: 100648193
SOC: 105205113
AEC: 105154146
ACEP: 105622703
HST: 105190066
CFO: 105250504
LHU: 105677360
PGC: 109863555
NVI: 100122372
TCA: 656767
DPA: 109543781
NVL: 108568702
API: 100169003
DNX: 107170068
ZNE: 110830315
FCD: 110845391
TUT: 107371826
CEL: CELE_EEED8.9(pink-1)
BMY: Bm1_23785
MYI: 110460906
OBI: 106876772
LAK: 106175425
SHX: MS3_00077
EPA: 110244759
ADF: 107352394
AQU: 100631577
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrane J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, Li C, Tieu K, Przedborski S
  Title
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
  Journal
Proc Natl Acad Sci U S A 107:378-83 (2010)
DOI:10.1073/pnas.0911187107
  Sequence
[hsa:65018]

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