KEGG   ORTHOLOGY: K05692Help
Entry
K05692                      KO                                     

Name
ACTB_G1
Definition
actin beta/gamma 1
Pathway
ko04015  Rap1 signaling pathway
ko04145  Phagosome
ko04210  Apoptosis
ko04390  Hippo signaling pathway
ko04391  Hippo signaling pathway - fly
ko04510  Focal adhesion
ko04520  Adherens junction
ko04530  Tight junction
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04714  Thermogenesis
ko04745  Phototransduction - fly
ko04810  Regulation of actin cytoskeleton
ko04919  Thyroid hormone signaling pathway
ko04921  Oxytocin signaling pathway
ko05100  Bacterial invasion of epithelial cells
ko05110  Vibrio cholerae infection
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05132  Salmonella infection
ko05164  Influenza A
ko05205  Proteoglycans in cancer
ko05225  Hepatocellular carcinoma
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
ko05416  Viral myocarditis
ko05418  Fluid shear stress and atherosclerosis
Disease
H00101  Other phagocyte defects
H00604  Deafness, autosomal dominant
H01255  Juvenile-onset dystonia
H01705  Bilateral sudden sensorineural hearing loss
H02023  Baraitser-Winter syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K05692  ACTB_G1; actin beta/gamma 1
   04390 Hippo signaling pathway
    K05692  ACTB_G1; actin beta/gamma 1
   04391 Hippo signaling pathway -fly
    K05692  ACTB_G1; actin beta/gamma 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K05692  ACTB_G1; actin beta/gamma 1
  09143 Cell growth and death
   04210 Apoptosis
    K05692  ACTB_G1; actin beta/gamma 1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05692  ACTB_G1; actin beta/gamma 1
   04520 Adherens junction
    K05692  ACTB_G1; actin beta/gamma 1
   04530 Tight junction
    K05692  ACTB_G1; actin beta/gamma 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05692  ACTB_G1; actin beta/gamma 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K05692  ACTB_G1; actin beta/gamma 1
   04670 Leukocyte transendothelial migration
    K05692  ACTB_G1; actin beta/gamma 1
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K05692  ACTB_G1; actin beta/gamma 1
   04919 Thyroid hormone signaling pathway
    K05692  ACTB_G1; actin beta/gamma 1
  09157 Sensory system
   04745 Phototransduction - fly
    K05692  ACTB_G1; actin beta/gamma 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K05692  ACTB_G1; actin beta/gamma 1
 09160 Human Diseases
  09161 Cancers
   05205 Proteoglycans in cancer
    K05692  ACTB_G1; actin beta/gamma 1
   05225 Hepatocellular carcinoma
    K05692  ACTB_G1; actin beta/gamma 1
  09165 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K05692  ACTB_G1; actin beta/gamma 1
   05410 Hypertrophic cardiomyopathy (HCM)
    K05692  ACTB_G1; actin beta/gamma 1
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K05692  ACTB_G1; actin beta/gamma 1
   05414 Dilated cardiomyopathy (DCM)
    K05692  ACTB_G1; actin beta/gamma 1
   05416 Viral myocarditis
    K05692  ACTB_G1; actin beta/gamma 1
  09167 Infectious diseases
   05110 Vibrio cholerae infection
    K05692  ACTB_G1; actin beta/gamma 1
   05130 Pathogenic Escherichia coli infection
    K05692  ACTB_G1; actin beta/gamma 1
   05132 Salmonella infection
    K05692  ACTB_G1; actin beta/gamma 1
   05131 Shigellosis
    K05692  ACTB_G1; actin beta/gamma 1
   05100 Bacterial invasion of epithelial cells
    K05692  ACTB_G1; actin beta/gamma 1
   05164 Influenza A
    K05692  ACTB_G1; actin beta/gamma 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery
    K05692  ACTB_G1; actin beta/gamma 1
   03019 Messenger RNA Biogenesis
    K05692  ACTB_G1; actin beta/gamma 1
   03036 Chromosome and associated proteins
    K05692  ACTB_G1; actin beta/gamma 1
   03029 Mitochondrial biogenesis
    K05692  ACTB_G1; actin beta/gamma 1
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05692  ACTB_G1; actin beta/gamma 1
   04147 Exosome
    K05692  ACTB_G1; actin beta/gamma 1
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   Coactivators
    BAF/PBAF complex
     K05692  ACTB_G1; actin beta/gamma 1
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Factors involved in mRNA localization
    Factors that have mRNA localization signals
     K05692  ACTB_G1; actin beta/gamma 1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HAT complexes
    TIP60 complex
     K05692  ACTB_G1; actin beta/gamma 1
    NuA4 complex
     K05692  ACTB_G1; actin beta/gamma 1
  Chromatin remodeling factors
   BAF complex
    K05692  ACTB_G1; actin beta/gamma 1
   PBAF complex
    K05692  ACTB_G1; actin beta/gamma 1
   SWR1 complex
    K05692  ACTB_G1; actin beta/gamma 1
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Actin cytoskeleton organization
    K05692  ACTB_G1; actin beta/gamma 1
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actins
    Actins
     K05692  ACTB_G1; actin beta/gamma 1
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K05692  ACTB_G1; actin beta/gamma 1
BRITE hierarchy
Genes
HSA: 60(ACTB) 71(ACTG1)
PTR: 450133(ACTB) 746570(ACTG1)
PPS: 100970542(ACTG1) 100987691 100987915(ACTB) 100987964 100990579 100993222
GGO: 101125802(ACTG1) 101127752(ACTB) 101148229 101152821
PON: 100173832(ACTB) 100441387(ACTG1)
NLE: 100598167(ACTG1) 100598411(ACTB)
MCC: 100428865 574285(ACTB) 713687(ACTG1)
MCF: 101925802(ACTG1) 102114946 102121291 102127542 102139853(ACTB)
CSAB: 103215020 103217237 103219323 103230823 103240948 103243719(ACTG1) 103246953(ACTB) 103246954
RRO: 104654953(ACTG1) 104657250 104659174 104660471 104665228(ACTB) 104668285 104671851 104672769 104675775 104676787 104677902 104680795 104681622 104681871
MMU: 11461(Actb) 11465(Actg1)
RNO: 100361457 287876(Actg1) 684969(Potef) 81822(Actb)
CGE: 100689477(Actb) 100764022(Actg1) 103159101
CCAN: 109700700 109702822(Actg1)
OCU: 100008822 100009272(ACTB)
TUP: 102479926(ACTB) 102498431(ACTG1)
CFA: 403580(ACTB) 475923(ACTG1)
AML: 100466132(ACTG1) 100481739(ACTB)
UMR: 103659865 103665813(ACTG1) 103670086(ACTB)
FCA: 100144392(ACTG1) 101098507(ACTB)
PTG: 102971401(ACTB) 102971629(ACTG1)
AJU: 106984514(ACTB) 106987399(ACTG1)
BTA: 280979(ACTB) 404122(ACTG1)
BOM: 102285564(ACTG1) 102286048(ACTB)
BIU: 109573916(ACTG1) 109578544(ACTB)
PHD: 102330463(ACTG1) 102341364(ACTB)
CHX: 100860883(ACTG1) 102179831(ACTB)
OAS: 443052(ACTB) 443340(ACTG1)
SSC: 397653(ACTG1) 414396(ACTB)
BACU: 103005004(ACTG1) 103015338(ACTB)
LVE: 103077223(ACTB) 103086383(ACTG1)
OOR: 101271282(ACTG1) 101277826(ACTB)
ECB: 100033878(ACTB) 100050139(ACTG1)
EPZ: 103547895(ACTB) 103551082(ACTG1)
MYB: 102251030 102256245(ACTB) 102263592(ACTG1)
MYD: 102766109(ACTG1) 102772396(ACTB)
HAI: 109380220(ACTB) 109393048(ACTG1)
RSS: 109449434(ACTG1) 109459292(ACTB)
PALE: 102884158(ACTG1) 102884469(ACTB)
LAV: 100654618(ACTB) 100670743(ACTG1)
GGA: 396526(ACTB) 415296(ACTG1) 776816
APLA: 101792739 101798056(ACTRT2) 101798233 101799398(ACTG1) 101800437(ACTB)
TGU: 100229883 751978(ACT5C)
GFR: 102040297(ACTG1) 102041442(ACTB) 102043209
FAB: 101808355 101813373(ACTB) 101815742(ACTG1)
PHI: 102106742(ACTB) 102110255 102111224(ACTG1)
PMAJ: 107209164 107211173(ACTB) 107212453(ACTG1)
CCW: 104684799(ACTB)
FPG: 101912716(ACTB) 101919774(ACTG1) 101924846
FCH: 102050787(ACTB) 102055927(ACTG1) 102056825
CMY: 102930389(ACTG1) 102932532 102934067(Actin-1) 102937126(ACTB) 102941516 102947623(Actin-1)
XTR: 394957(actg1) 407952(actb) 448563(actb)
NPR: 108796718(ACTG1) 108799803
DRE: 57934(actb1) 57935(actb2)
AMEX: 103030443(actb) 103039558
NCC: 104951171(actb) 104965067
CMK: 103175484(actg1) 103181320 103183476(actl9) 103184202(actrt2) 103186865(actb)
DME: Dmel_CG10067(Act57B) Dmel_CG12051(Act42A) Dmel_CG18290(Act87E) Dmel_CG4027(Act5C) Dmel_CG5178(Act88F) Dmel_CG5409(Arp53D) Dmel_CG7478(Act79B)
DSI: Dsimw501_GD10342(Dsim_GD10342) Dsimw501_GD11215(Dsim_GD11215) Dsimw501_GD11548(Dsim_GD11548) Dsimw501_GD15015(Dsim_GD15015) Dsimw501_GD16764(Dsim_GD16764) Dsimw501_GD18909(Dsim_GD18909) Dsimw501_GD19025(Dsim_Act88F)
DVI: Dvir_GJ10425(Dvir_ActE1) Dvir_GJ13903(Dvir_ActD1) Dvir_GJ14747 Dvir_GJ17479(Dvir_ActC2) Dvir_GJ18395 Dvir_GJ20999 Dvir_GJ22881(Dvir_ActE2)
AME: 102653846 406122(Arp1) 410075(GB12614) 551176(GB18527) 551369(GB18365) 552637(GB12453) 725404 725739 725851
PMAC: 106710491
CEL: CELE_M03F4.2(act-4) CELE_T04C12.4(act-3) CELE_T04C12.5(act-2) CELE_T04C12.6(act-1) CELE_T25C8.2(act-5)
BVG: 104885815
PDA: 103700236
SCE: YFL039C(ACT1)
ERC: Ecym_1520
KMX: KLMA_70051(ACT)
NCS: NCAS_0C03700(NCAS0C03700)
NDI: NDAI_0G03040(NDAI0G03040)
TPF: TPHA_0D00250(TPHA0D00250)
TBL: TBLA_0C00440(TBLA0C00440)
TDL: TDEL_0C00470(TDEL0C00470)
KAF: KAFR_0D00940(KAFR0D00940)
PIC: PICST_69529(ACT1)
CAL: CAALFM_C113700WA(ACT1)
CDU: CD36_12690(ACT1)
CAUR: QG37_03382
SLB: AWJ20_3882(ACT1)
NCR: NCU04173(act)
NTE: NEUTE1DRAFT115707(NEUTE1DRAFT_115707)
MGR: MGG_03982
MAW: MAC_05223
MAJ: MAA_07556
BFU: BCIN_16g02020(BcactA)
MBE: MBM_03210
ANI: AN6542.2
ANG: ANI_1_106134(An15g00560)
PCS: Pc20g11630(act)
ABE: ARB_04092
TVE: TRV_03874
PTE: PTT_08677
SPO: SPBC32H8.12c(act1)
CNE: CNA04650
CNB: CNBA4460
HIR: HETIRDRAFT_147003(act1.2) HETIRDRAFT_408649(act1.1)
ABP: AGABI1DRAFT112248(AGABI1DRAFT_112248) AGABI1DRAFT126481(AGABI1DRAFT_126481)
ABV: AGABI2DRAFT117354(AGABI2DRAFT_117354) AGABI2DRAFT192120(AGABI2DRAFT_192120)
WSE: WALSEDRAFT_41424(Act1p)
MGL: MGL_1986
DDI: DDB_G0269902(act26) DDB_G0289507(act25)
SMIN: v1.2.002714.t1(symbB.v1.2.002714.t1) v1.2.003779.t1(symbB.v1.2.003779.t1) v1.2.011075.t1(symbB.v1.2.011075.t1) v1.2.011649.t1(symbB.v1.2.011649.t1) v1.2.014251.t1(symbB.v1.2.014251.t1) v1.2.014252.t1(symbB.v1.2.014252.t1) v1.2.014253.t1(symbB.v1.2.014253.t1) v1.2.015238.t1(symbB.v1.2.015238.t1) v1.2.015239.t1(symbB.v1.2.015239.t1) v1.2.015239.t2(symbB.v1.2.015239.t2) v1.2.031093.t1(symbB.v1.2.031093.t1)
FCY: FRACYDRAFT_171145(ACTIN_3) FRACYDRAFT_209894(ACTIN_1) FRACYDRAFT_269912(ACTIN_2)
TPS: THAPSDRAFT_25772(ACT1)
SPAR: SPRG_10352
HOH: Hoch_1671
LOKI: Lokiarch_09100(barP_1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2795655
  Authors
Krause M, Wild M, Rosenzweig B, Hirsh D
  Title
Wild-type and mutant actin genes in Caenorhabditis elegans.
  Journal
J Mol Biol 208:381-92 (1989)
DOI:10.1016/0022-2836(89)90503-2
  Sequence
Reference
PMID:1734024
  Authors
Ohmori H, Toyama S, Toyama S
  Title
Direct proof that the primary site of action of cytochalasin on cell motility processes is actin.
  Journal
J Cell Biol 116:933-41 (1992)
DOI:10.1083/jcb.116.4.933
  Sequence
[hsa:60]
Reference
PMID:3737401
  Authors
Erba HP, Gunning P, Kedes L
  Title
Nucleotide sequence of the human gamma cytoskeletal actin mRNA: anomalous evolution of vertebrate non-muscle actin genes.
  Journal
Nucleic Acids Res 14:5275-94 (1986)
DOI:10.1093/nar/14.13.5275
  Sequence
[hsa:71]

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