KEGG   ORTHOLOGY: K06679Help
Entry
K06679                      KO                                     

Name
MAD1
Definition
mitotic spindle assembly checkpoint protein MAD1
Pathway
ko04111  Cell cycle - yeast
ko04113  Meiosis - yeast
ko04114  Oocyte meiosis
ko05166  HTLV-I infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04111 Cell cycle - yeast
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
   04113 Meiosis - yeast
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
   04114 Oocyte meiosis
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
 09160 Human Diseases
  09167 Infectious diseases
   05166 HTLV-I infection
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
BRITE hierarchy
Genes
SCE: YGL086W(MAD1)
AGO: AGOS_AFL065C
KLA: KLLA0_E19141g
KMX: KLMA_60359(MAD1)
LTH: KLTH0H04774g
VPO: Kpol_1002p64
ZRO: ZYRO0G08250g
CGR: CAGL0H03179g
NCS: NCAS_0D03670(NCAS0D03670)
NDI: NDAI_0I01220(NDAI0I01220)
TPF: TPHA_0J02260(TPHA0J02260)
TBL: TBLA_0B05160(TBLA0B05160)
TDL: TDEL_0G01570(TDEL0G01570)
KAF: KAFR_0C02150(KAFR0C02150)
PIC: PICST_53034(MAD1)
CAL: CAALFM_C112660WA(CaO19.6357)
CAUR: QG37_06152
NCR: NCU04428
NTE: NEUTE1DRAFT121192(NEUTE1DRAFT_121192)
MGR: MGG_04908
MAW: MAC_00255
MAJ: MAA_08191
CMT: CCM_08765
BFU: BCIN_15g05340(Bcmad1)
MBE: MBM_01602
ANI: AN0696.2
ANG: ANI_1_944074(An08g06660)
ABE: ARB_07734
TVE: TRV_00479
PTE: PTT_16480
SPO: SPBC3D6.04c(mad1)
CNE: CNJ02500
CNB: CNBJ0960
ABP: AGABI1DRAFT109561(AGABI1DRAFT_109561)
ABV: AGABI2DRAFT188863(AGABI2DRAFT_188863)
MGL: MGL_3198
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kim IG, Rhee DK, Jeong JW, Kim SC, Won M, Lee J, Song KW, Kim HB
  Title
Mad1p, a component of the spindle assembly checkpoint in fission yeast, suppresses a novel septation-defective mutant, sun1, in a cell-division cycle.
  Journal
FEMS Microbiol Lett 227:183-8 (2003)
DOI:10.1016/S0378-1097(03)00607-4
  Sequence

KEGG   ORTHOLOGY: K02537Help
Entry
K02537                      KO                                     

Name
MAD2
Definition
mitotic spindle assembly checkpoint protein MAD2
Pathway
ko04110  Cell cycle
ko04111  Cell cycle - yeast
ko04113  Meiosis - yeast
ko04114  Oocyte meiosis
ko04914  Progesterone-mediated oocyte maturation
ko05166  HTLV-I infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
   04111 Cell cycle - yeast
    K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
   04113 Meiosis - yeast
    K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
   04114 Oocyte meiosis
    K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
 09160 Human Diseases
  09167 Infectious diseases
   05166 HTLV-I infection
    K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
BRITE hierarchy
Genes
HSA: 4085(MAD2L1)
PTR: 461661(MAD2L1)
PPS: 100991053(MAD2L1)
GGO: 101154425(MAD2L1)
PON: 100447417(MAD2L1)
NLE: 100583633(MAD2L1)
MCC: 708574(MAD2L1)
MCF: 102143003(MAD2L1)
CSAB: 103236183(MAD2L1)
RRO: 104663595(MAD2L1)
RBB: 108520042(MAD2L1)
CJC: 100390703(MAD2L1)
SBQ: 101036641(MAD2L1)
MMU: 56150(Mad2l1)
RNO: 297176(Mad2l1)
CGE: 100753081(Mad2l1)
NGI: 103743357(Mad2l1)
OCU: 100354882(MAD2L1)
TUP: 102469874(MAD2L1)
CFA: 476070(MAD2L1)
AML: 105239272(MAD2L1)
UMR: 103661788(MAD2L1)
ORO: 101366015(MAD2L1)
FCA: 101092847(MAD2L1)
PTG: 102960455(MAD2L1)
AJU: 106979581(MAD2L1)
BTA: 337870(MAD2L1)
BOM: 102265441
BIU: 109560214
PHD: 102321386
CHX: 102191505(MAD2L1)
OAS: 101109094(MAD2L1)
SSC: 100523455(MAD2L1)
CFR: 102519401(MAD2L1)
CDK: 105093650(MAD2L1)
BACU: 102998401(MAD2L1)
LVE: 103075103(MAD2L1)
OOR: 101270682(MAD2L1)
ECB: 100072353(MAD2L1)
EPZ: 103540579(MAD2L1)
EAI: 106847276(MAD2L1)
MYD: 102771060(MAD2L1)
HAI: 109371173(MAD2L1)
RSS: 109454141(MAD2L1)
PALE: 102882657(MAD2L1) 102894232
MDO: 100018245(MAD2L1)
SHR: 100915179(MAD2L1)
OAA: 100081525(MAD2L1)
GGA: 422675(MAD2L1)
MGP: 100539967(MAD2L1)
CJO: 107313563(MAD2L1)
APLA: 101798731(MAD2L1)
ACYG: 106038609(MAD2L1)
TGU: 100218172(MAD2L1)
GFR: 102034691(MAD2L1)
FAB: 101815586(MAD2L1)
PHI: 102103464(MAD2L1)
PMAJ: 107203050(MAD2L1)
CCW: 104693708(MAD2L1)
FPG: 101922567(MAD2L1)
FCH: 102057276(MAD2L1)
CLV: 102091219(MAD2L1)
EGZ: 104121946(MAD2L1)
AAM: 106491842(MAD2L1)
ASN: 102386165(MAD2L1)
AMJ: 102563766(MAD2L1)
PSS: 102443905(MAD2L1)
CMY: 102930107(MAD2L1)
CPIC: 101944183(MAD2L1)
ACS: 100566557(mad2l1)
PVT: 110072864(MAD2L1)
PBI: 103053681(MAD2L1)
GJA: 107117277(MAD2L1)
XLA: 380433(mad2l1.S) 414724(mad2l1.L)
XTR: 100125170(mad2l1)
NPR: 108799278(MAD2L1)
DRE: 550434(mad2l1)
SGH: 107559834(mad2l1) 107571931
IPU: 100528709(mad2l1)
AMEX: 103023436(mad2l1)
TRU: 101063203(mad2l1)
LCO: 104925007(mad2l1)
OLA: 100301583(mad2l1)
XMA: 102223876(mad2l1)
PRET: 103480085(mad2l1)
NFU: 107395348(mad2l1)
CSEM: 103388845(mad2l1)
HCQ: 109520346(mad2l1)
BPEC: 110158728(mad2l1)
SASA: 100195682(md2l1) 106577502
ELS: 105020769(mad2l1)
SFM: 108921040(mad2l1)
LCM: 102349134(MAD2L1)
CMK: 103177366(mad2l1)
CIN: 100176682
SPU: 592941
APLC: 110984973
SKO: 100369181
DME: Dmel_CG17498(mad2)
DSI: Dsimw501_GD17595(Dsim_GD17595)
MDE: 101892969
AAG: 5570415
AME: 102656337
BIM: 100742480
BTER: 100649509
SOC: 105201750
AEC: 105151493
ACEP: 105619891
PBAR: 105425232
HST: 105181397
CFO: 105253919
LHU: 105668239
PGC: 109853043
NVI: 100113849
TCA: 656102(mad2)
DPA: 109537438
NVL: 108558832
BMOR: 101742054
PMAC: 106710976
PRAP: 110997904
PXY: 105380616
API: 100163039(Mad2)
DNX: 107167574
ZNE: 110829671
FCD: 110844655
TUT: 107362512
CEL: CELE_Y69A2AR.30(mdf-2)
CBR: CBG13880(Cbr-mdf-2)
BMY: Bm1_37300
CRG: 105335419
MYI: 110467354
OBI: 106881040
SHX: MS3_00092
EPA: 110254748
ATH: AT3G25980(MAD2)
CRB: 17885143
THJ: 104805258
CPAP: 110825093
TCC: 18609687
EGR: 104433641
VRA: 106755568
VAR: 108328480
CAM: 101491886
ADU: 107468947
AIP: 107624467
LANG: 109327407
FVE: 101293550
PAVI: 110753129
PXB: 103949882
ZJU: 107428398
CSV: 101208371
CMO: 103488916
MCHA: 111019657
RCU: 8278426
JCU: 105644758
VVI: 100254488
SLY: 101257469
SPEN: 107019014
SOT: 102590157
CANN: 107846865
NSY: 104233104
NTO: 104095047
INI: 109178649
SIND: 105168368
DCR: 108205700
BVG: 104897639
SOE: 110792981
NNU: 104592962
OSA: 4336215
DOSA: Os04t0486500-01(Os04g0486500)
OBR: 102705998
BDI: 100829553
ATS: 109781090(LOC109781090)
SBI: 8073686
ZMA: 100277636 542621(mad2)
SITA: 101773586
PDA: 103723308
MUS: 103988672
DCT: 110104486
ATR: 18435000
PPP: 112280969
CRE: CHLREDRAFT_130117(MAD2)
MNG: MNEG_9980
MIS: MICPUN_98250(MAD2)
APRO: F751_1029
SCE: YJL030W(MAD2)
ERC: Ecym_8258
KMX: KLMA_20696(MAD2)
NCS: NCAS_0A01410(NCAS0A01410)
NDI: NDAI_0C02330(NDAI0C02330)
TPF: TPHA_0N00970(TPHA0N00970)
TBL: TBLA_0D03440(TBLA0D03440)
TDL: TDEL_0E03820(TDEL0E03820)
KAF: KAFR_0J01100(KAFR0J01100)
CAL: CAALFM_C104080WA(MAD2)
CAUR: QG37_01318
SLB: AWJ20_719(MAD2)
NCR: NCU05781
NTE: NEUTE1DRAFT131523(NEUTE1DRAFT_131523)
MAW: MAC_05380
MAJ: MAA_07751
CMT: CCM_05717
BFU: BCIN_04g04220(Bcmad2)
MBE: MBM_05008
ANI: AN2511.2
ANG: ANI_1_512084(An09g04120)
ABE: ARB_00710
TVE: TRV_00163
PTE: PTT_13185
ZTR: MYCGRDRAFT_33976(MAD2)
SPO: SPBC20F10.06(mad2)
CNE: CNC01510
CNB: CNBC5740
ABP: AGABI1DRAFT110183(AGABI1DRAFT_110183)
ABV: AGABI2DRAFT189921(AGABI2DRAFT_189921)
MGL: MGL_2637
DFA: DFA_01655
SMIN: v1.2.022091.t1(symbB.v1.2.022091.t1) v1.2.022091.t2(symbB.v1.2.022091.t2)
PTI: PHATRDRAFT_51024(Pt-MAD2)
SPAR: SPRG_06295
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lau DT, Murray AW
  Title
Mad2 and Mad3 cooperate to arrest budding yeast in mitosis.
  Journal
Curr Biol 22:180-90 (2012)
DOI:10.1016/j.cub.2011.12.029
Reference
  Authors
Mapelli M, Filipp FV, Rancati G, Massimiliano L, Nezi L, Stier G, Hagan RS, Confalonieri S, Piatti S, Sattler M, Musacchio A
  Title
Determinants of conformational dimerization of Mad2 and its inhibition by p31comet.
  Journal
EMBO J 25:1273-84 (2006)
DOI:10.1038/sj.emboj.7601033
  Sequence
[hsa:4085]

KEGG   ORTHOLOGY: K06680Help
Entry
K06680                      KO                                     

Name
MAD3
Definition
spindle assembly checkpoint component MAD3
Pathway
ko04111  Cell cycle - yeast
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04111 Cell cycle - yeast
    K06680  MAD3; spindle assembly checkpoint component MAD3
BRITE hierarchy
Genes
SCE: YJL013C(MAD3)
CGR: CAGL0G06930g
YLI: YALI0B23166g
SPO: SPCC1795.01c(mad3)
LBC: LACBIDRAFT_297584
TaxonomyKoalaUniProt
Reference
  Authors
Hardwick KG, Johnston RC, Smith DL, Murray AW
  Title
MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p.
  Journal
J Cell Biol 148:871-82 (2000)
DOI:10.1083/jcb.148.5.871
  Sequence
[sce:YJL013C]

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