KEGG   ORTHOLOGY: K07376Help
Entry
K07376                      KO                                     

Name
PRKG1
Definition
cGMP-dependent protein kinase 1 [EC:2.7.11.12]
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04540  Gap junction
ko04611  Platelet activation
ko04713  Circadian entrainment
ko04714  Thermogenesis
ko04730  Long-term depression
ko04740  Olfactory transduction
ko04923  Regulation of lipolysis in adipocytes
ko04970  Salivary secretion
Module
M00694  cGMP signaling
Disease
H00801  Familial thoracic aortic aneurysm and dissection (TAAD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP - PKG signaling pathway
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09154 Digestive system
   04970 Salivary secretion
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09156 Nervous system
   04730 Long-term depression
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09157 Sensory system
   04740 Olfactory transduction
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K07376  PRKG1; cGMP-dependent protein kinase 1
   04714 Thermogenesis
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07376  PRKG1; cGMP-dependent protein kinase 1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00694  cGMP signaling
     K07376  PRKG1; cGMP-dependent protein kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.12  cGMP-dependent protein kinase
     K07376  PRKG1; cGMP-dependent protein kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  PKG family
   K07376  PRKG1; cGMP-dependent protein kinase 1
BRITE hierarchy
Other DBs
GO: 0004692
Genes
HSA: 5592(PRKG1)
PTR: 744467(PRKG1)
PPS: 100975252(PRKG1)
GGO: 101148943(PRKG1)
PON: 100437791(PRKG1)
NLE: 100597697(PRKG1)
MCC: 703356(PRKG1)
MCF: 102122483(PRKG1)
CSAB: 103216192(PRKG1)
RRO: 104676729(PRKG1)
CJC: 100388016(PRKG1)
SBQ: 101043597(PRKG1)
MMU: 19091(Prkg1)
RNO: 54286(Prkg1)
CGE: 100768615(Prkg1)
NGI: 103732508(Prkg1)
HGL: 101708361(Prkg1)
CCAN: 109700389(Prkg1)
OCU: 100008694(PRKG1)
TUP: 102471472 102497341(PRKG1)
CFA: 609616(PRKG1)
AML: 100481505
UMR: 103661993(PRKG1)
FCA: 101097420(PRKG1)
PTG: 102969150(PRKG1)
AJU: 106969513
BTA: 282004(PRKG1)
BOM: 102279305(PRKG1)
BIU: 109579117(PRKG1)
PHD: 102344359(PRKG1)
CHX: 102182753(PRKG1)
OAS: 443010(PRKG1)
SSC: 733640(PRKG1)
CFR: 102509252(PRKG1)
CDK: 105085256(PRKG1)
BACU: 103012801(PRKG1)
LVE: 103071917(PRKG1)
OOR: 101279276(PRKG1)
ECB: 100071872(PRKG1)
EPZ: 103556704 103563033(PRKG1)
EAI: 106847454(PRKG1)
MYB: 102255009(PRKG1)
HAI: 109387521(PRKG1)
RSS: 109450854(PRKG1)
PALE: 102884723(PRKG1)
LAV: 100662471(PRKG1)
MDO: 100023016(PRKG1)
SHR: 100928746(PRKG1)
OAA: 100073431(PRKG1)
GGA: 423682(PRKG1)
MGP: 100540173(PRKG1)
CJO: 107315639(PRKG1)
APLA: 101802614(PRKG1)
ACYG: 106030263(PRKG1)
GFR: 102041315(PRKG1)
FAB: 101816835(PRKG1)
PHI: 102105641(PRKG1)
PMAJ: 107207071(PRKG1)
CCW: 104695105(PRKG1)
FPG: 101914750(PRKG1)
FCH: 102051167(PRKG1)
CLV: 102098659(PRKG1)
EGZ: 104125151(PRKG1)
AAM: 106483994 106486427(PRKG1)
ASN: 102385836(PRKG1)
AMJ: 102573015(PRKG1)
PSS: 102462425(PRKG1) 102463494
CMY: 102942713(PRKG1)
CPIC: 101953224(PRKG1)
ACS: 100563289
PBI: 103062615(PRKG1) 103064267
GJA: 107113865(PRKG1)
XLA: 108696071 108697357(prkg1.S)
XTR: 100494278(prkg1)
NPR: 108797031(PRKG1)
DRE: 394005(prkg1a)
IPU: 108263833(PRKG1) 108265376 108274270(prkg1)
CMK: 103180883(prkg1) 103190998
CIN: 100184124
SPU: 585077
DSI: Dsimw501_GD22740(Dsim_GD22740) Dsimw501_GD22942(Dsim_GD22942) Dsimw501_GD23660(Dsim_GD23660)
AME: 406092(For) 551714(GB12535)
SOC: 105195528 105202008(foraging)
NVI: 100114234 100117965(NV50043) 100119839(for)
BMOR: 101735910 692605(PKG-I)
CEL: CELE_F55A8.2(egl-4)
CBR: CBG08401(Cbr-egl-4)
BMY: Bm1_37920
TSP: Tsp_02535
HMG: 100199173 100201371(prkg1)
AQU: 100636239
PPP: 112291101
CRE: CHLREDRAFT_181974(CGK2)
MNG: MNEG_5029
PYO: PY17X_1009800(PY02304)
PCB: PCHAS_100910(PC000298.03.0)
TAN: TA04955
TPV: TP03_0511
BBO: BBOV_I004690(19.m02237)
CPV: cgd8_750
TGO: TGME49_311360(PKG)
SMIN: v1.2.000817.t1(symbB.v1.2.000817.t1) v1.2.000877.t1(symbB.v1.2.000877.t1) v1.2.004287.t1(symbB.v1.2.004287.t1) v1.2.006098.t1(symbB.v1.2.006098.t1) v1.2.008273.t1(symbB.v1.2.008273.t1) v1.2.008273.t2(symbB.v1.2.008273.t2) v1.2.009118.t1(symbB.v1.2.009118.t1) v1.2.009164.t1(symbB.v1.2.009164.t1) v1.2.010262.t1(symbB.v1.2.010262.t1) v1.2.010262.t2(symbB.v1.2.010262.t2) v1.2.011180.t1(symbB.v1.2.011180.t1) v1.2.012476.t1(symbB.v1.2.012476.t1) v1.2.012476.t2(symbB.v1.2.012476.t2) v1.2.015884.t1(symbB.v1.2.015884.t1) v1.2.016972.t2(symbB.v1.2.016972.t2) v1.2.017815.t1(symbB.v1.2.017815.t1) v1.2.022723.t1(symbB.v1.2.022723.t1) v1.2.023087.t1(symbB.v1.2.023087.t1) v1.2.023463.t1(symbB.v1.2.023463.t1) v1.2.023465.t1(symbB.v1.2.023465.t1) v1.2.023864.t1(symbB.v1.2.023864.t1) v1.2.027542.t1(symbB.v1.2.027542.t1) v1.2.031517.t1(symbB.v1.2.031517.t1) v1.2.031929.t1(symbB.v1.2.031929.t1) v1.2.033790.t1(symbB.v1.2.033790.t1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sausbier M, Schubert R, Voigt V, Hirneiss C, Pfeifer A, Korth M, Kleppisch T, Ruth P, Hofmann F
  Title
Mechanisms of NO/cGMP-dependent vasorelaxation.
  Journal
Circ Res 87:825-30 (2000)
DOI:10.1161/01.RES.87.9.825
  Sequence
[mmu:19091]

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