KEGG   ORTHOLOGY: K08018Help
Entry
K08018                      KO                                     

Name
RAPGEF2, PDZGEF1
Definition
Rap guanine nucleotide exchange factor 2
Pathway
ko04010  MAPK signaling pathway
ko04015  Rap1 signaling pathway
ko04530  Tight junction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
   04010 MAPK signaling pathway
    K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
BRITE hierarchy
Genes
HSA: 9693(RAPGEF2)
PTR: 461577(RAPGEF2)
PPS: 100972977(RAPGEF2)
GGO: 101154294(RAPGEF2)
PON: 100444094(RAPGEF2)
NLE: 100594311(RAPGEF2)
MCC: 704717(RAPGEF2)
MCF: 102145680(RAPGEF2)
CSAB: 103236456(RAPGEF2)
RRO: 104677918(RAPGEF2)
RBB: 108520366
CJC: 100388886(RAPGEF2)
SBQ: 101033151(RAPGEF2)
MMU: 76089(Rapgef2)
RNO: 310533(Rapgef2)
CGE: 100754995(Rapgef2) 107977704
NGI: 103751016(Rapgef2)
HGL: 101718791(Rapgef2)
CCAN: 109689106
OCU: 100346752(RAPGEF2)
TUP: 102476593(RAPGEF2)
CFA: 100856359(RAPGEF2)
AML: 100484273(RAPGEF2)
UMR: 103658068(RAPGEF2)
ORO: 101373494(RAPGEF2)
FCA: 101084954(RAPGEF2)
PTG: 102950679(RAPGEF2)
AJU: 106967455(RAPGEF2)
BTA: 100139484(RAPGEF2)
BOM: 102275520(RAPGEF2)
BIU: 109571167(RAPGEF2)
PHD: 102329096(RAPGEF2)
CHX: 102187973(RAPGEF2)
OAS: 101111578(RAPGEF2)
SSC: 100517409(RAPGEF2)
CFR: 102510135(RAPGEF2)
CDK: 105094767(RAPGEF2)
BACU: 103005459
LVE: 103076487(RAPGEF2)
OOR: 101274731(RAPGEF2)
ECB: 100069003(RAPGEF2)
EPZ: 103545519(RAPGEF2)
EAI: 106823789(RAPGEF2)
MYB: 102244394(RAPGEF2)
MYD: 102762387(RAPGEF2)
HAI: 109395998(RAPGEF2)
RSS: 109448149(RAPGEF2)
PALE: 102879764(RAPGEF2)
LAV: 100670174(RAPGEF2)
TMU: 101340649
MDO: 100023159(RAPGEF2)
SHR: 100923893(RAPGEF2)
OAA: 100079239(RAPGEF2)
GGA: 422418(RAPGEF2)
MGP: 100549357(RAPGEF2)
CJO: 107313022
APLA: 101802476(RAPGEF2)
ACYG: 106032300
TGU: 100224541(RAPGEF2)
GFR: 102042003(RAPGEF2)
FAB: 101805788(RAPGEF2)
PHI: 102109398(RAPGEF2)
PMAJ: 107203090(RAPGEF2)
CCW: 104697194(RAPGEF2)
FPG: 101920342(RAPGEF2)
FCH: 102060194(RAPGEF2)
CLV: 102086538(RAPGEF2)
EGZ: 104124157(RAPGEF2)
AAM: 106491974
ASN: 102382228(RAPGEF2)
AMJ: 102563879(RAPGEF2)
PSS: 102457114(RAPGEF2)
CMY: 102941224(RAPGEF2)
CPIC: 101940840(RAPGEF2)
ACS: 100561833(rapgef2)
PVT: 110072791(RAPGEF2)
GJA: 107109403
XLA: 108706643 447229(rapgef2.L)
XTR: 100145659(rapgef2)
NPR: 108791705(RAPGEF2)
DRE: 557693(rapgef2) 793952(si:dkey-253i9.4)
AMEX: 103034322(rapgef2) 103036243
TRU: 101068626(rapgef2)
LCO: 104932582(rapgef2)
NCC: 104941952(rapgef2)
MZE: 101469290(rapgef2)
OLA: 101158677(rapgef2)
XMA: 102216833(rapgef2)
PRET: 103471849(rapgef2)
NFU: 107380014(rapgef2)
CSEM: 103390684(rapgef2)
LCF: 108885198(rapgef2)
HCQ: 109526251(rapgef2)
BPEC: 110153676(rapgef2)
SASA: 106604533(rapgef2) 106611555
ELS: 105027765(rapgef2)
SFM: 108924469(rapgef2) 108930833
LCM: 102349377(RAPGEF2)
CMK: 103182258(rapgef2)
CIN: 100179213
SPU: 577944 591190(rapgef2)
APLC: 110987331
DME: Dmel_CG9491(PDZ-GEF)
DSI: Dsimw501_GD23402(Dsim_GD23402)
MDE: 101891421
AAG: 5566803
AME: 408810(GB20093)
BIM: 100745022
BTER: 100648358
SOC: 105203629
AEC: 105143272
ACEP: 105623391
PBAR: 105426200
HST: 105185384
CFO: 105248938
LHU: 105678707
PGC: 109856330
NVI: 100119820
TCA: 655931
DPA: 109534373
NVL: 108564103
BMOR: 101747113
PMAC: 106721665
PRAP: 110997433
PXY: 105382413
API: 100162402
DNX: 107163614
ZNE: 110841549
FCD: 110845730
TUT: 107371050
CEL: CELE_T14G10.2(pxf-1)
CBR: CBG03403(Cbr-pxf-1)
BMY: Bm1_36455
CRG: 105329799
MYI: 110447077
OBI: 106881120
SHX: MS3_07678
EPA: 110254157
HMG: 100198794(rapgef6)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kuiperij HB, de Rooij J, Rehmann H, van Triest M, Wittinghofer A, Bos JL, Zwartkruis FJ
  Title
Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2.
  Journal
Biochim Biophys Acta 1593:141-9 (2003)
DOI:10.1016/S0167-4889(02)00365-8
Reference
  Authors
de Rooij J, Boenink NM, van Triest M, Cool RH, Wittinghofer A, Bos JL
  Title
PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2.
  Journal
J Biol Chem 274:38125-30 (1999)
DOI:10.1074/jbc.274.53.38125
  Sequence
[hsa:9693]

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