KEGG   ORTHOLOGY: K08675Help
Entry
K08675                      KO                                     

Name
PRSS15, PIM1
Definition
ATP-dependent Lon protease [EC:3.4.21.53]
Disease
H01824  CODAS syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.53  endopeptidase La
     K08675  PRSS15, PIM1; ATP-dependent Lon protease
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S16: lon protease family
   K08675  PRSS15, PIM1; ATP-dependent Lon protease
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
BRITE hierarchy
Genes
HSA: 9361(LONP1)
PTR: 455623(LONP1)
PON: 100461951(LONP1)
MCC: 700284(LONP1)
MMU: 74142(Lonp1)
RNO: 170916(Lonp1)
CFA: 611425(LONP1)
AML: 100468447(LONP1)
BTA: 510796(LONP1)
SSC: 100511917(LONP1)
ECB: 100065045(LONP1)
MDO: 100024990(LONP1)
OAA: 100074993(LONP1)
GGA: 768942(LONP1)
MGP: 100538450(LONP1)
TGU: 100221382(LONP1)
XLA: 108712696(lonp1.L)
XTR: 100492505(lonp1)
DRE: 563257(lonp1)
CIN: 100178941
SPU: 100889553
DME: Dmel_CG8798(Lon)
DER: 6545346
DWI: 6643034
AAG: 5568011
AME: 409459
NVI: 100119946
TCA: 661788
API: 100162246
CEL: CELE_C34B2.6(lonp-1) CELE_Y75B8A.4(lonp-2)
CBR: CBG12802
BMY: Bm1_18860
ATH: AT3G05780(LON3) AT3G05790(LON4) AT5G26860(LON1)
VVI: 100254508
BDI: 100844749
SBI: 8077511
ZMA: 732810(LON2)
SCE: YBL022C(PIM1)
CAL: CAALFM_CR04340WA(PIM1)
NCR: NCU05261
MGR: MGG_11141
BFU: BCIN_07g06160(Bcpim1)
ANI: AN6193.2
ANG: ANI_1_516024(An02g03760)
SPO: SPAC22F3.06c(lon1)
CNB: CNBD2440
MGL: MGL_4002
TAN: TA12745
TPV: TP02_0361
BBO: BBOV_III006020(17.m07531)
PPU: PP_1443(lon-I)
PST: PSPTO_4210(lon-2)
PEN: PSEEN4367(lon-2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bota DA, Davies KJ
  Title
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism.
  Journal
Nat Cell Biol 4:674-80 (2002)
DOI:10.1038/ncb836
Reference
  Authors
Lu B, Yadav S, Shah PG, Liu T, Tian B, Pukszta S, Villaluna N, Kutejova E, Newlon CS, Santos JH, Suzuki CK
  Title
Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance.
  Journal
J Biol Chem 282:17363-74 (2007)
DOI:10.1074/jbc.M611540200

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