KEGG ORTHOLOGY: K09108

ORTHOLOGY: K09108

Entry

K09108                      KO

Symbol

TFAP4

Name

transcription factor AP-4

Pathway

map05205

Proteoglycans in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K09108  TFAP4; transcription factor AP-4
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09108  TFAP4; transcription factor AP-4
Transcription factors [BR:ko03000]
Eukaryotic type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Ubiquitous bHLH-ZIP factors
    K09108  TFAP4; transcription factor AP-4

Genes

HSA:	7023(TFAP4)

PTR:	748090(TFAP4)

PPS:	100983876(TFAP4)

GGO:	101146500(TFAP4)

PON:	100446026(TFAP4)

NLE:	100597662(TFAP4)

HMH:	116462448(TFAP4)

MCC:	707513(TFAP4)

MCF:	102139344(TFAP4)

MTHB:

126944685

MNI:	105467847(TFAP4)

CSAB:

103227610(TFAP4)

CATY:

105572101(TFAP4)

PANU:

101005019(TFAP4)

TGE:	112614284(TFAP4)

RRO:	104654693(TFAP4)

RBB:	108538235(TFAP4)

TFN:	117097723(TFAP4)

PTEH:

111551741(TFAP4)

CANG:

105525686(TFAP4)

CJC:	100391868(TFAP4)

SBQ:	101043319(TFAP4)

CIMI:

108286551(TFAP4)

CSYR:

103273692(TFAP4)

MMUR:

105859739(TFAP4)

LCAT:

123632323(TFAP4)

PCOQ:

105813018(TFAP4)

OGA:	100944090(TFAP4)

MMU:	83383(Tfap4)

MCAL:

110311601(Tfap4)

MPAH:

110329696(Tfap4)

RNO:	360482(Tfap4)

MCOC:

116084251(Tfap4)

ANU:	117710456(Tfap4)

MUN:	110545962(Tfap4)

CGE:	100751080(Tfap4)

MAUA:

101843520(Tfap4)

PROB:

127219619(Tfap4)

PLEU:

114710633(Tfap4)

MORG:

121463763(Tfap4)

MFOT:

126493323

AAMP:

119813378(Tfap4)

NGI:	103744483(Tfap4)

HGL:	101715683(Tfap4)

CPOC:

100718065(Tfap4)

CCAN:

109681693(Tfap4)

DORD:

105982238(Tfap4)

DSP:	122123885(Tfap4)

PLOP:

125340578(Tfap4)

NCAR:

124970124

MMMA:

107146662(Tfap4)

OCU:

100337937

OPI:	101536010(TFAP4)

TUP:	102476108(TFAP4)

GVR:	103591386(TFAP4)

CFA:	490029(TFAP4)

CLUD:

112640441(TFAP4)

VVP:	112923268(TFAP4)

VLG:	121488240(TFAP4)

NPO:	129519710(TFAP4)

AML:	100474477(TFAP4)

UMR:	103668552(TFAP4)

UAH:	113270853(TFAP4)

UAR:	123783277(TFAP4)

ELK:

111156154

LLV:

125090811

MPUF:

101677565(TFAP4)

MNP:	132026952(TFAP4)

MLK:	131819344(TFAP4)

NVS:	122895901(TFAP4)

ORO:	101366788(TFAP4)

EJU:	114219915(TFAP4)

ZCA:	113932731(TFAP4)

MLX:	118021778(TFAP4)

NSU:	110587976(TFAP4)

LWW:	102728052(TFAP4)

FCA:	101095461(TFAP4)

PYU:	121019597(TFAP4)

PCOO:

112853313(TFAP4)

PBG:	122471734(TFAP4)

PVIV:

125154775(TFAP4)

LRUF:

124517963

PTG:	102959143(TFAP4)

PPAD:

109278251(TFAP4)

PUC:

125927251

AJU:

106978806

HHV:	120236513(TFAP4)

BTA:	540757(TFAP4)

BOM:	102286208(TFAP4)

BIU:	109578793(TFAP4)

BBUB:

102405151(TFAP4)

BBIS:

104988987(TFAP4)

CHX:	102188373(TFAP4)

OAS:	101122654(TFAP4)

BTAX:

128071424(TFAP4)

ODA:	120874362(TFAP4)

CCAD:

122433332(TFAP4)

MBEZ:

129545327(TFAP4)

SSC:	110259938(TFAP4)

CFR:	102504738(TFAP4)

CBAI:

105064794(TFAP4)

CDK:	105099826(TFAP4)

VPC:	102543055(TFAP4)

BACU:

103014489(TFAP4)

BMUS:

118882069(TFAP4)

LVE:	103069922(TFAP4)

OOR:	101281153(TFAP4)

DLE:	111185251(TFAP4)

PCAD:

102996355(TFAP4)

PSIU:

116740986(TFAP4)

NASI:

112409337(TFAP4)

ECB:	100069711(TFAP4)

EPZ:	103553953(TFAP4)

EAI:	106825967(TFAP4)

MYB:	102256010(TFAP4)

MYD:	102761282(TFAP4)

MMYO:

118656211(TFAP4)

MLF:	102420659(TFAP4)

PKL:	118703353(TFAP4)

EFUS:

103286153(TFAP4)

MNA:	107535820(TFAP4)

DRO:	112298362(TFAP4)

SHON:

118975809(TFAP4)

AJM:	119056244(TFAP4)

PDIC:

114499952(TFAP4)

PHAS:

123807256(TFAP4)

MMF:	118642350(TFAP4)

PPAM:

129083645(TFAP4)

HAI:	109392123(TFAP4)

RFQ:	117019863(TFAP4)

PALE:

102885005(TFAP4)

PGIG:

120620333(TFAP4)

PVP:	105303094(TFAP4)

RAY:	107521698(TFAP4)

MJV:	108406466(TFAP4)

TOD:	119241981(TFAP4)

SARA:

101557684(TFAP4)

SETR:

126001262(TFAP4)

LAV:	100663165(TFAP4)

TMU:

101345440

ETF:	101662665(TFAP4)

DNM:	101441721(TFAP4)

MDO:	100013756(TFAP4)

GAS:	123230977(TFAP4)

SHR:	100925765(TFAP4)

AFZ:

127542128

PCW:	110214579(TFAP4)

OAA:	100093136(TFAP4)

GGA:	430233(TFAP4)

PCOC:

116230254(TFAP4)

MGP:

100542863

CJO:	107320990(TFAP4)

TPAI:

128078956(TFAP4)

LMUT:

125700681(TFAP4)

NMEL:

110405927(TFAP4)

APLA:

101790556(TFAP4)

ACYG:

106033323(TFAP4)

CATA:

118249309(TFAP4)

AFUL:

116495220(TFAP4)

TGU:	100226417(TFAP4)

LSR:	110476093(TFAP4)

SCAN:

103817928(TFAP4)

PMOA:

120513268(TFAP4)

OTC:	121337505(TFAP4)

PRUF:

121350924(TFAP4)

GFR:	102042980(TFAP4)

FAB:	101818920(TFAP4)

OMA:	130259394(TFAP4)

PHI:	102103129(TFAP4)

PMAJ:

107210965(TFAP4)

CCAE:

111945790(TFAP4)

CCW:	104684952(TFAP4)

ETL:	114057024(TFAP4)

ZAB:	102068165(TFAP4)

ACHL:

103802822(TFAP4)

SVG:	106862902(TFAP4)

MMEA:

130577219(TFAP4)

HRT:	120759678(TFAP4)

FPG:	101920624(TFAP4)

FCH:	102048012(TFAP4)

CLV:	102095889(TFAP4)

EGZ:	104121970(TFAP4)

NNI:	104023509(TFAP4)

ACUN:

113485718(TFAP4)

TALA:

116962970(TFAP4)

AFOR:

103898355(TFAP4)

ACHC:

115335980(TFAP4)

HLE:	104838648(TFAP4)

AGEN:

126033996

MUI:	104534577(TFAP4)

NNT:	104411124(TFAP4)

SHAB:

115606456(TFAP4)

DPUB:

104300294(TFAP4)

CPEA:

104386835(TFAP4)

AVIT:

104272918(TFAP4)

CVF:	104283745(TFAP4)

RTD:	128914301(TFAP4)

CUCA:

104068176(TFAP4)

AAM:	106482384(TFAP4)

AROW:

112965833(TFAP4)

NPD:	112955642(TFAP4)

TGT:	104569771(TFAP4)

DNE:	112986918(TFAP4)

SCAM:

104143914(TFAP4)

ASN:	102373604(TFAP4)

AMJ:	102566800(TFAP4)

CPOO:

109313538(TFAP4)

GGN:	109290790(TFAP4)

PSS:	102450652(TFAP4)

CMY:	102930254(TFAP4)

CCAY:

125644228(TFAP4)

DCC:	119862890(TFAP4)

CPIC:

101938867(TFAP4)

TST:	117883900(TFAP4)

CABI:

116825538(TFAP4)

MRV:	120373548(TFAP4)

ACS:	100556024(tfap4)

ASAO:

132782060(TFAP4)

PVT:	110089135(TFAP4)

SUND:

121914946(TFAP4)

PBI:	103049176(TFAP4)

PMUR:

107283976(TFAP4)

CTIG:

120315780(TFAP4)

TSR:	106551741(TFAP4)

PGUT:

117679460(TFAP4)

APRI:

131185305(TFAP4)

PTEX:

113438891(TFAP4)

NSS:	113422436(TFAP4)

VKO:	123025129(TFAP4)

PMUA:

114584283(TFAP4)

PRAF:

128401279(TFAP4)

ZVI:	118092612(TFAP4)

HCG:	128336825(TFAP4)

GJA:	107109290(TFAP4)

STOW:

125431162(TFAP4)

EMC:	129338166(TFAP4)

XLA:	108701636(tfap4.L) 108703190(tfap4.S)

XTR:	100170601(tfap4)

NPR:	108790829(TFAP4)

RTEM:

120943335(TFAP4)

BBUF:

121008969(TFAP4)

BGAR:

122945032(TFAP4)

MUO:	115475765(TFAP4)

GSH:	117369325(TFAP4)

DRE:	100318080(tfap4)

SRX:	107715644 107718566

SANH:

107661646 107695712

SGH:	107553667 107601578

CCAR:

109046522(tfap4) 109046523 109076933

CAUA:

113051728 113067437 113067626

CGIB:

127952017 127955463

PTET:

122340916(tfap4)

LROH:

127163255(tfap4)

OMC:	131537777(tfap4)

PPRM:

120489530(tfap4)

RKG:	130095070(tfap4)

MAMB:

125262412(tfap4)

CIDE:

127509330

MASI:

127450263 127452003

TROS:

130561873(tfap4)

TDW:	130426740 130426790(tfap4)

MANU:

129436662(tfap4)

IPU:

108258278

IFU:	128624954(tfap4)

PHYP:

113528492(tfap4)

SMEO:

124396526(tfap4)

TFD:	113639640(tfap4)

TVC:	132861237(tfap4)

AMEX:

103031420(tfap4)

CMAO:

118821427(tfap4)

EEE:	113576820(tfap4)

CHAR:

105896886 105898169(tfap4)

TRU:	101074652 101078828

TFS:	130514858(tfap4) 130527585

TNG:	GSTEN00001007G001 GSTEN00018511G001 GSTEN00026312G001

LCO:	104925377 104925701(tfap4)

NCC:	104952749 104960154(tfap4)

TBEN:

117474717 117492505(tfap4)

CGOB:

115012360 115015251

PGEO:

117450544(tfap4) 117465963

GACU:

117548759(tfap4) 117561733

EMAC:

134864972 134878636(tfap4)

ELY:	117255761 117268012(tfap4)

EFO:	125879017(tfap4) 125886095

PLEP:

121942182 121956099(tfap4)

SLUC:

116042816 116059347(tfap4)

ECRA:

117958102 117958130(tfap4)

ESP:	116702857 116704589

PFLV:

114547389 114569013(tfap4)

GAT:	120824995 120827583(tfap4)

PPUG:

119218673 119219953(tfap4)

AFB:	129095704 129098397(tfap4)

CLUM:

117735227(tfap4) 117735605

PSWI:

130189123(tfap4) 130189481

MSAM:

119889828(tfap4) 119899438

SCHU:

122869101(tfap4) 122873546

CUD:	121508972 121529159(tfap4)

ALAT:

119014530(tfap4) 119025305

MZE:	101465792 101477868

ONL:	100704439 100710780

OAU:	116310611 116321428(tfap4)

OLA:	101157191 101175405

OML:	112137496 112146960(tfap4)

CSAI:

133422101(tfap4) 133443948

XMA:	102231357 102231784

XCO:	114145054 114160166

XHE:	116720424 116735843

PRET:

103463841 103469188

PFOR:

103141002(tfap4) 103154142

PLAI:

106942562(tfap4) 106945968

PMEI:

106915776(tfap4) 106922029

GAF:	122821603(tfap4) 122829728

PPRL:

129363941(tfap4) 129367304

CVG:	107083438 107095216(tfap4)

CTUL:

119773187(tfap4) 119798036

GMU:	124862675 124863769 124868848

NFU:	107376483(tfap4) 107390529

KMR:	108241425 108247652(tfap4)

ALIM:

106518705(tfap4) 106532501

NWH:	119420991(tfap4) 119422765

AOCE:

111569934 111582517

MCEP:

124998504(tfap4) 125004491

CSEM:

103384089 103393053(tfap4)

POV:	109627661 109638735

SSEN:

122771524 122785648(tfap4)

HHIP:

117761485 117766537(tfap4)

HSP:	118123043 118123637(tfap4)

SMAU:

118288845(tfap4) 118312401

LCF:	108885410 108886157

SDU:	111227187(tfap4) 111229299

SLAL:

111665588 111667582(tfap4)

XGL:	120788453(tfap4) 120800978

HCQ:	109527339 109532531

SSCV:

125969251 125983486

SBIA:

133506402 133514262(tfap4)

PEE:	133403749 133415385(tfap4)

PTAO:

133466140(tfap4) 133476292

BPEC:

110166200 110169351(tfap4)

MALB:

109972275 109972901(tfap4)

BSPL:

114851879 114860728(tfap4)

SJO:	128378590(tfap4) 128380938

SASA:

106564468 106564517 106564640 106590423 106597862 106597991 106606492

STRU:

115147403 115171778 115178080 115206473

OTW:	112238370 112238622(tfap4)

OMY:	110485548 110487015 110495098 118938337

OGO:	123999453(tfap4) 124015971

ONE:

115115760

OKI:	109880251 109880255 109880864

OKE:	118375013(tfap4) 118389349

SALP:

111956000 112077645

SNH:	120032539 120039949 120041324

CCLU:

121551255 121553816

ELS:	105012106 105021644

SFM:	108928808 108930225

PKI:	111843293 111860584

AANG:

118217028(tfap4) 118219863

LOC:	102695352(tfap4)

PSPA:

121300464 121331031

ARUT:

117418587(tfap4) 117973652

PSEX:

120542301(tfap4)

LCM:	102345721(TFAP4)

CMK:	103178728(tfap4) 103189245

RTP:	109922716 109932687(tfap4)

CPLA:

122542302 122560626(tfap4)

HOC:	132825181(tfap4) 132831496

LERI:

129706905(tfap4) 129713873

PMRN:

116951463(TFAP4)

LRJ:	133340612(TFAP4)

BFO:

118418987

BBEL:

109470622

CIN:	778539(ap4)

SPU:

LPIC:

APLC:

AJC:

SKO:

AAG:

AALB:

CPII:

AME:

ACER:

ALAB:

ADR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

MDL:

CGLO:

FAS:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

100144574(Tfap4)

BMAN:

114246089

MSEX:

115445421

DPL:	KGM_208497

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PGW:

CCRN:

API:

DNX:

AGS:	114128724 114128725

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM602530

FOC:

TPAL:

ZNE:

CSEC:

BROR:

FCD:

DPX:	DAPPUDRAFT_303137

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:	129222536 129231339

SDM:

118182055

LPOL:

106457219 106462636 106462723 106478123

CEL:	CELE_F58A4.7(hlh-11)

CBR:	CBG_10034(Cbr-hlh-11)

CRQ:	GCK72_009478

NAI:	NECAME_04511

BMY:	BM_BM4538(Bma-hlh-11)

LOA:	LOAG_07256

HRO:	HELRODRAFT_176727

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_103540.1

SHX:	MS3_00008013(TFAP4_1)

OVI:	T265_08622

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

TAD:	TRIADDRAFT_56276

AQU:

100635737

» show all

Reference

PMID:7933101

Authors

Ou SH, Garcia-Martinez LF, Paulssen EJ, Gaynor RB

Title

Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.

Journal

J Virol 68:7188-99 (1994)
DOI:10.1128/JVI.68.11.7188-7199.1994

Sequence

[hsa:7023]

Reference

PMID:18818310

Authors

Jung P, Menssen A, Mayr D, Hermeking H

Title

AP4 encodes a c-MYC-inducible repressor of p21.

Journal

Proc Natl Acad Sci U S A 105:15046-51 (2008)
DOI:10.1073/pnas.0801773105

Sequence

[hsa:7023]

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Gene (1366)   
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   RefGene (605)   
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Literature (2)   
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