KEGG ORTHOLOGY: K12804

ORTHOLOGY: K12804

Entry

K12804                      KO

Symbol

PSTPIP1

Name

proline-serine-threonine phosphatase interacting protein 1

Pathway

map04621

NOD-like receptor signaling pathway

Disease

H00287

Pyogenic sterile arthritis, pyoderma gangrenosum, and acne syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12804  PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12804  PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Bin/Amphiphysin/Rvs (BAR) family proteins
   F-BAR proteins
    K12804  PSTPIP1; proline-serine-threonine phosphatase interacting protein 1

Genes

HSA:	9051(PSTPIP1)

PTR:	100613166(PSTPIP1)

PON:	100449454(PSTPIP1)

NLE:	100598955(PSTPIP1)

HMH:	116482563(PSTPIP1)

MCC:	708327(PSTPIP1)

MCF:	102128978(PSTPIP1)

MTHB:

126960006

MNI:	105491018(PSTPIP1)

CSAB:

103245274(PSTPIP1)

CATY:

105601336(PSTPIP1)

PANU:

101022104(PSTPIP1)

TGE:	112627867(PSTPIP1)

MLEU:

105541587(PSTPIP1)

RRO:	104670089(PSTPIP1)

RBB:	108528518(PSTPIP1)

TFN:	117070341(PSTPIP1)

PTEH:

111530433(PSTPIP1)

CANG:

105505129(PSTPIP1)

CJC:	100406340(PSTPIP1)

SBQ:	101052332(PSTPIP1)

CIMI:

108296000(PSTPIP1)

CSYR:

103257694(PSTPIP1)

MMUR:

105882058(PSTPIP1)

LCAT:

123624689(PSTPIP1)

PCOQ:

105816457(PSTPIP1)

OGA:	100964952(PSTPIP1)

MMU:	19200(Pstpip1)

MCAL:

110301923(Pstpip1)

MPAH:

110328148(Pstpip1)

RNO:	300732(Pstpip1)

MCOC:

116072082(Pstpip1)

ANU:	117699200(Pstpip1)

MUN:	110566271(Pstpip1)

CGE:	100765031(Pstpip1)

MAUA:

101842060(Pstpip1)

PROB:

127231780(Pstpip1)

PLEU:

114690315(Pstpip1)

MORG:

121438303(Pstpip1)

MFOT:

126486932

AAMP:

119809816(Pstpip1)

NGI:	103726044(Pstpip1)

HGL:	101723975(Pstpip1)

CPOC:

100732350(Pstpip1)

CCAN:

109697411(Pstpip1)

DORD:

105982498(Pstpip1)

DSP:	122123426(Pstpip1)

PLOP:

125368238(Pstpip1)

NCAR:

124978001

MMMA:

107137922(Pstpip1)

OCU:

103345318

OPI:	101526759(PSTPIP1)

TUP:	102479779(PSTPIP1)

GVR:	103609243(PSTPIP1)

CFA:	611757(PSTPIP1)

CLUD:

112675543(PSTPIP1)

VVP:	112913261(PSTPIP1)

VLG:	121485579(PSTPIP1)

NPO:	129506318(PSTPIP1)

AML:	100473221(PSTPIP1)

UMR:	103678964(PSTPIP1)

UAH:	113241007(PSTPIP1)

UAR:	123790651(PSTPIP1)

ELK:	111153103 111153380

LLV:

125104664

MPUF:

101690189(PSTPIP1)

MNP:	131999140(PSTPIP1)

MLK:	131835748(PSTPIP1)

NVS:	122893003(PSTPIP1)

ORO:	101370765(PSTPIP1)

EJU:	114200507(PSTPIP1)

ZCA:	113908859(PSTPIP1)

MLX:	118002967(PSTPIP1)

NSU:	110583942(PSTPIP1)

LWW:	102736289(PSTPIP1)

FCA:	101100213(PSTPIP1)

PYU:	121041427(PSTPIP1)

PCOO:

112855511(PSTPIP1)

PBG:	122468385(PSTPIP1)

PVIV:

125168257(PSTPIP1)

LRUF:

124508953

PTG:	102950378(PSTPIP1)

PPAD:

109262645(PSTPIP1)

PUC:

125908946

AJU:

106985237

HHV:	120235763(PSTPIP1)

BTA:	513924(PSTPIP1)

BOM:	102285323(PSTPIP1)

BIU:	109575656(PSTPIP1)

BBUB:

102416670(PSTPIP1)

BBIS:

104990959(PSTPIP1)

CHX:	102187808(PSTPIP1)

OAS:	101116939(PSTPIP1)

BTAX:

128066721(PSTPIP1)

ODA:	120875485(PSTPIP1)

CCAD:

122455173(PSTPIP1)

MBEZ:

129550424(PSTPIP1)

SSC:	100152628(PSTPIP1)

CFR:	102520466(PSTPIP1)

CBAI:

105069163(PSTPIP1)

CDK:	105087228(PSTPIP1)

VPC:	102536186(PSTPIP1)

BACU:

103017173(PSTPIP1)

BMUS:

118890346(PSTPIP1)

LVE:	103084287(PSTPIP1)

OOR:	101274282(PSTPIP1)

DLE:	111177854(PSTPIP1)

PCAD:

102988731(PSTPIP1)

PSIU:

116746191(PSTPIP1)

NASI:

112410942(PSTPIP1)

ECB:	100050881(PSTPIP1)

EPZ:	103564744(PSTPIP1)

EAI:	106831299(PSTPIP1)

MYB:	102246938(PSTPIP1)

MYD:	102775185(PSTPIP1)

MMYO:

118676300(PSTPIP1)

MLF:	102427837(PSTPIP1)

PKL:	118728349(PSTPIP1)

EFUS:

103303877(PSTPIP1)

MNA:	107538057(PSTPIP1)

DRO:	112301695(PSTPIP1)

SHON:

118987720(PSTPIP1)

AJM:	119038683(PSTPIP1)

PDIC:

114489697(PSTPIP1)

PHAS:

123825274(PSTPIP1)

MMF:	118643458(PSTPIP1)

PPAM:

129085610(PSTPIP1)

HAI:	109375337(PSTPIP1)

RFQ:	117023553(PSTPIP1)

PALE:

102883260(PSTPIP1)

PGIG:

120597910(PSTPIP1)

PVP:	105306866(PSTPIP1)

RAY:	107510504(PSTPIP1)

MJV:	108402704(PSTPIP1)

TOD:	119238391(PSTPIP1)

SARA:

101555394(PSTPIP1)

LAV:	100672535(PSTPIP1)

TMU:

101359185

ETF:	101641657(PSTPIP1)

DNM:	101438212(PSTPIP1)

MDO:	100025253(PSTPIP1)

GAS:	123236500(PSTPIP1)

SHR:	100923195(PSTPIP1)

AFZ:

127552066

PCW:	110200615(PSTPIP1)

OAA:	103169236(PSTPIP1)

GGA:	415349(PSTPIP1)

PCOC:

116244573(PSTPIP1)

CJO:	107318652(PSTPIP1)

TPAI:

128075140(PSTPIP1)

LMUT:

125698233(PSTPIP1)

NMEL:

110403573(PSTPIP1)

APLA:

101790362(PSTPIP1)

ACYG:

106044213(PSTPIP1)

CATA:

118251622(PSTPIP1)

AFUL:

116493500(PSTPIP1)

TGU:	100218412(PSTPIP1)

LSR:	110477553(PSTPIP1)

SCAN:

103823176(PSTPIP1)

PMOA:

120513292(PSTPIP1)

OTC:	121348343(PSTPIP1)

PRUF:

121365492(PSTPIP1)

GFR:	102033261(PSTPIP1)

FAB:	101805745(PSTPIP1)

OMA:	130257454(PSTPIP1)

PHI:	102111384(PSTPIP1)

PMAJ:

107209340(PSTPIP1)

CCAE:

111934250(PSTPIP1)

CCW:	104697449(PSTPIP1)

CBRC:

103622928(PSTPIP1)

ETL:	114064693(PSTPIP1)

ZAB:	102071946(PSTPIP1)

ACHL:

103798883(PSTPIP1)

SVG:	106854935(PSTPIP1)

MMEA:

130575058(PSTPIP1)

HRT:	120759000(PSTPIP1)

FPG:	101922705(PSTPIP1)

FCH:	102053249(PSTPIP1)

CLV:	102093910(PSTPIP1)

EGZ:	104130850(PSTPIP1)

NNI:	104016732(PSTPIP1)

PCRI:

104032046(PSTPIP1)

PLET:

104624727(PSTPIP1)

EHS:	104507194(PSTPIP1)

PCAO:

104050262(PSTPIP1)

ACUN:

113484034(PSTPIP1)

TALA:

104359246(PSTPIP1)

PADL:

103922041(PSTPIP1)

AFOR:

103898554(PSTPIP1)

ACHC:

115342147(PSTPIP1)

HALD:

104314691(PSTPIP1)

HLE:	104834404(PSTPIP1)

AGEN:

126043311

GCL:

127020563

CCRI:

104154945(PSTPIP1)

CMAC:

104476446(PSTPIP1)

MUI:	104539673(PSTPIP1)

BREG:

104643138(PSTPIP1)

FGA:	104077159(PSTPIP1)

GSTE:

104256822(PSTPIP1)

LDI:	104346598(PSTPIP1)

MNB:	103772785(PSTPIP1)

OHA:	104335475(PSTPIP1)

NNT:	104410424(PSTPIP1)

SHAB:

115612895(PSTPIP1)

DPUB:

104306070(PSTPIP1)

PGUU:

104471743(PSTPIP1)

ACAR:

104528425(PSTPIP1)

CPEA:

104385963(PSTPIP1)

AVIT:

104279554(PSTPIP1)

CVF:	104287940(PSTPIP1)

RTD:	128914436(PSTPIP1)

CUCA:

104066291(PSTPIP1)

TEO:	104372189(PSTPIP1)

BRHI:

104491363

AAM:	106496439(PSTPIP1)

AROW:

112967280(PSTPIP1)

NPD:	112946732(PSTPIP1)

TGT:	104565091(PSTPIP1)

DNE:	112988760(PSTPIP1)

SCAM:

104148363(PSTPIP1)

ASN:	102384611(PSTPIP1)

AMJ:	102560566(PSTPIP1)

CPOO:

109308891(PSTPIP1)

GGN:	109288721(PSTPIP1)

PSS:	102449303(PSTPIP1)

CMY:	102932540(PSTPIP1)

CCAY:

125644264(PSTPIP1)

DCC:	119862859(PSTPIP1)

CPIC:

101947383(PSTPIP1)

TST:	117884305(PSTPIP1)

CABI:

116836294(PSTPIP1)

MRV:	120373855(PSTPIP1)

ACS:	100566825(pstpip1)

ASAO:

132762598(PSTPIP1)

PVT:	110087171(PSTPIP1)

SUND:

121932401(PSTPIP1)

PBI:	103063525(PSTPIP1)

PMUR:

107289268(PSTPIP1)

CTIG:

120305575(PSTPIP1)

PGUT:

117661017(PSTPIP1)

APRI:

131184923(PSTPIP1)

PTEX:

113442318(PSTPIP1)

NSS:	113423239(PSTPIP1)

VKO:	123033726(PSTPIP1)

PMUA:

114604258(PSTPIP1)

PRAF:

128420765(PSTPIP1)

ZVI:	118083613(PSTPIP1)

HCG:	128334871(PSTPIP1)

GJA:	107109701(PSTPIP1)

STOW:

125446119(PSTPIP1)

EMC:	129345495(PSTPIP1)

XLA:	108711276(pstpip1.L) 447609(pstpip1.S)

XTR:	100379705(pstpip1)

NPR:	108796191(PSTPIP1)

RTEM:

120931553(PSTPIP1)

BBUF:

120985591(PSTPIP1)

BGAR:

122929727(PSTPIP1)

MUO:	115457734(PSTPIP1)

GSH:	117347968(PSTPIP1)

DRE:	571331(pstpip1a) 641582(pstpip1b)

SRX:	107715239 107725740 107741409 107750641

SANH:

107670725 107690351 107691132 107700386

SGH:	107562121 107567896 107585972 107594553

CCAR:

109056588 109077262 109108880

CAUA:

113049520 113052290 113061639 113118492

CGIB:

127934446 127961086 127977208 128016984

PTET:

122323031(pstpip1a) 122348046(pstpip1b)

LROH:

127168631(pstpip1b) 127180767(pstpip1a)

OMC:	131524811(pstpip1a) 131544926(pstpip1b)

PPRM:

120473182(pstpip1b) 120487692(pstpip1a)

RKG:	130088928(pstpip1a) 130101563(pstpip1b)

MAMB:

125254348(pstpip1a) 125264699(pstpip1b)

CIDE:

127499755 127515140

MASI:

127412129 127416258 127416818 127455927

TROS:

130556535(pstpip1b) 130563264(pstpip1a)

TDW:	130421098(pstpip1b) 130435896(pstpip1a)

MANU:

129418589(pstpip1a) 129442532 129442656 129442667

AMEX:

103046241(pstpip1)

CMAO:

118801362(pstpip1a) 118819142(pstpip1b)

EEE:	113576592(pstpip1) 113583492

CHAR:

105905582(pstpip1a)

TRU:	101062992 101065355(pstpip1)

TFS:	130521556 130536205

TNG:	GSTEN00015942G001 GSTEN00021448G001

LCO:	104917774 104917840(pstpip1)

NCC:	104946597 104947250

TBEN:

117471603 117491377(pstpip1a)

CGOB:

115006277 115010266

PGEO:

117440062 117447656(pstpip1a)

GACU:

117556681 117557670(pstpip1a)

EMAC:

134863390 134877973(pstpip1a)

ELY:	117260494 117262430(pstpip1a)

EFO:	125887199(pstpip1a) 125904305

PLEP:

121950252(pstpip1a) 121961158

SLUC:

116038555(pstpip1a) 116060606

ECRA:

117947647 117949218(pstpip1a)

ESP:	116690617 116694070

PFLV:

114559786 114561287

GAT:	120809034(pstpip1a) 120812726 120835114

PPUG:

119195709(pstpip1a) 119196750(pstpip1b)

AFB:	129101547 129108390(pstpip1a)

CLUM:

117725899(pstpip1b) 117732106(pstpip1a)

PSWI:

130193153 130195954(pstpip1a)

MSAM:

119885013 119890338(pstpip1b) 119894118(pstpip1a)

SCHU:

122873793(pstpip1b) 122874353(pstpip1a)

CUD:	121511165(pstpip1b) 121514921(pstpip1a)

ALAT:

119018346(pstpip1b) 119024535(pstpip1a)

MZE:	101473069 101487370

ONL:	100700076 100700785

OAU:	116314691(pstpip1b) 116326243(pstpip1a)

OLA:	101156493 101174493

OML:	112151763(pstpip1a) 112161319(pstpip1b)

CSAI:

133444237(pstpip1a) 133456525

XMA:	102221102 102228179

XCO:	114143373 114151469(pstpip1)

XHE:	116718871 116732697(pstpip1)

PRET:

103462592 103466606

PFOR:

103147831 103149883

PLAI:

106945589 106946148

PMEI:

106920791 106928283(pstpip1)

GAF:	122835300(pstpip1a) 122846804

PPRL:

129364183(pstpip1b) 129365474(pstpip1a)

CVG:	107082790(pstpip1) 107105107

CTUL:

119772463(pstpip1a) 119780712

GMU:	124866872 124879843(pstpip1a)

NFU:	107381549 107388780

KMR:	108229819(pstpip1a) 108237417(pstpip1b)

ALIM:

106514356(pstpip1) 106534257

NWH:	119415736(pstpip1a) 119426224

AOCE:

111580159(pstpip1) 111587590

MCEP:

125005703(pstpip1b) 125015247(pstpip1a)

CSEM:

103379385 103380310(pstpip1)

POV:	109624342 109624918

SSEN:

122769884(pstpip1a) 122772574

HHIP:

117759149(pstpip1b) 117762566(pstpip1a)

HSP:	118109179(pstpip1a) 118113437(pstpip1b)

SMAU:

118302455 118314677(pstpip1a)

LCF:	108875280(pstpip1a) 108877030

SDU:	111221465 111228555(pstpip1)

SLAL:

111659169 111667008(pstpip1)

XGL:	120793083(pstpip1a) 120793796

HCQ:	109513963 109531180

SSCV:

125966843 125971115

SBIA:

133498073 133502674(pstpip1a)

PEE:	133397293(pstpip1b) 133403304(pstpip1a)

PTAO:

133474258 133478357(pstpip1a)

BPEC:

110156539 110175260

MALB:

109954587 109966304(pstpip1)

BSPL:

114852484 114856865(pstpip1a)

SJO:	128359035(pstpip1a) 128359399

SASA:

106561158 106562406 106562467 106573496 106587680

STRU:

115152003 115166993 115196748 115203327

OTW:	112218582 112246932 112247476 112252406

OMY:	110495782 110506762 110521117 110526640

OGO:	124001141 124033560 124035537 124036509

ONE:	115109419 115112777 115120518 115134241

OKI:	109867315 109881534 109882254 109889367

OKE:	118362688 118375495 118396725(pstpip1a) 118401215

SALP:

111952956 111962416 112068316 112075211

SNH:	120039630 120040387 120053944 120066272

CCLU:

121531913 121576609 121580141

ELS:	105022635 105025684

SFM:	108931692 108940843

PKI:	111843575 111846641

AANG:

118214704(pstpip1a) 118227617

LOC:	102698401(pstpip1)

PSPA:

121294595 121298846

ARUT:

117428116 117429477

PSEX:

120541620(pstpip1a)

LCM:	102348654(PSTPIP1)

CMK:	103188307(pstpip1a)

CPLA:

122542541(pstpip1a)

HOC:

132834760

LERI:

129713488(pstpip1a)

PMRN:

116950818 116953549

LRJ:	133354195(PSTPIP1) 133355039

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

PVM:

PJA:

PCHN:

CQD:

PTRU:

ESN:

EAF:

TCF:

CSCU:

LPOL:

LGI:	LOTGIDRAFT_105043

PVUL:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:	125656072 125661596

PMAX:

MMER:

RPHI:

DPOL:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:	124450909 124452209

HMG:

100213763

HSY:

130633989

AQU:

100634782

MBR:	MONBRDRAFT_23448

SRE:	PTSG_01307

DPP:	DICPUDRAFT_48387

DFA:

DFA_06582

» show all

Reference

PMID:14595024

Authors

Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, Kastner DL

Title

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway.

Journal

Proc Natl Acad Sci U S A 100:13501-6 (2003)
DOI:10.1073/pnas.2135380100

Reference

PMID:9857189

Authors

Li J, Nishizawa K, An W, Hussey RE, Lialios FE, Salgia R, Sunder-Plassmann R, Reinherz EL

Title

A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.

Journal

EMBO J 17:7320-36 (1998)
DOI:10.1093/emboj/17.24.7320

Sequence

[hsa:9051]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (1086)   
   KEGG GENES (574)   
   KEGG MGENES (255)   
   RefGene (253)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (1093)   

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