KEGG   ORTHOLOGY: K14425
Entry
K14425                      KO                                     
Symbol
SLC12A1, NKCC2
Name
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
Disease
H00239  Bartter syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K14425  SLC12A1, NKCC2; solute carrier family 12 (sodium/potassium/chloride transporter), member 1
   04147 Exosome
    K14425  SLC12A1, NKCC2; solute carrier family 12 (sodium/potassium/chloride transporter), member 1
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC12: Electroneutral cation-coupled Cl cotransporter
   K14425  SLC12A1, NKCC2; solute carrier family 12 (sodium/potassium/chloride transporter), member 1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K14425  SLC12A1, NKCC2; solute carrier family 12 (sodium/potassium/chloride transporter), member 1
Other DBs
GO: 0008511
TC: 2.A.30.1.1 2.A.30.1.2
Genes
HSA: 6557(SLC12A1)
PTR: 453410(SLC12A1)
PPS: 100988563(SLC12A1)
GGO: 101124814(SLC12A1)
PON: 100173185(SLC12A1)
NLE: 100590969(SLC12A1)
HMH: 116482587(SLC12A1)
MCC: 714289(SLC12A1)
MCF: 102124487(SLC12A1)
MTHB: 126958687
MNI: 105490718(SLC12A1)
CSAB: 103245673(SLC12A1)
CATY: 105588240(SLC12A1)
PANU: 101012717(SLC12A1) 116268499
TGE: 112627578(SLC12A1)
MLEU: 105529985(SLC12A1)
RRO: 104657946(SLC12A1)
RBB: 108530111(SLC12A1)
TFN: 117070695(SLC12A1)
PTEH: 111552772(SLC12A1)
CANG: 105502181(SLC12A1)
CJC: 100414428(SLC12A1)
SBQ: 101035783(SLC12A1)
CIMI: 108315655(SLC12A1)
CSYR: 103272474
MMUR: 105870736(SLC12A1)
LCAT: 123622321(SLC12A1)
PCOQ: 105814263(SLC12A1)
OGA: 100944049(SLC12A1)
MMU: 20495(Slc12a1)
MCAL: 110310437(Slc12a1)
MPAH: 110319615(Slc12a1)
RNO: 25065(Slc12a1)
MCOC: 116092339(Slc12a1)
ANU: 117703343(Slc12a1)
MUN: 110545292(Slc12a1)
CGE: 100761861(Slc12a1)
MAUA: 101841063(Slc12a1)
PROB: 127221524(Slc12a1)
PLEU: 114683900(Slc12a1)
MORG: 121465600(Slc12a1)
MFOT: 126496819
AAMP: 119814415(Slc12a1)
NGI: 103747094(Slc12a1)
HGL: 101719170(Slc12a1)
CPOC: 100716647(Slc12a1)
CCAN: 109684251(Slc12a1)
DORD: 105981098(Slc12a1)
DSP: 122114559(Slc12a1)
PLOP: 125341007(Slc12a1)
NCAR: 124976775
MMMA: 107137796(Slc12a1)
OCU: 100328575(SLC12A1)
OPI: 101522441(SLC12A1)
TUP: 102483235(SLC12A1)
GVR: 103609076
CFA: 478292(SLC12A1)
CLUD: 112675964(SLC12A1)
VVP: 112920042(SLC12A1)
VLG: 121482666(SLC12A1)
NPO: 129506134(SLC12A1)
AML: 100476129(SLC12A1)
UMR: 103676712(SLC12A1)
UAH: 113269588(SLC12A1)
UAR: 123801849(SLC12A1)
ELK: 111160858
LLV: 125105273
MPUF: 101686164(SLC12A1)
MNP: 131999731(SLC12A1)
MLK: 131836246(SLC12A1)
NVS: 122893178(SLC12A1)
ORO: 101374182(SLC12A1)
EJU: 114203059 114203060
ZCA: 113909150(SLC12A1)
MLX: 118003722(SLC12A1)
NSU: 110583804(SLC12A1)
LWW: 102730754(SLC12A1)
FCA: 101100216(SLC12A1)
PYU: 121041664(SLC12A1)
PCOO: 112855342(SLC12A1)
PBG: 122468680(SLC12A1)
PVIV: 125168049(SLC12A1)
LRUF: 124508061
PTG: 102952923(SLC12A1)
PPAD: 109263025(SLC12A1)
PUC: 125909982
AJU: 106967214
HHV: 120220849(SLC12A1)
BTA: 407161(SLC12A1)
BOM: 102282438(SLC12A1)
BIU: 109565153(SLC12A1)
BBUB: 102408643(SLC12A1)
BBIS: 104988267(SLC12A1)
CHX: 102181306(SLC12A1)
OAS: 101111371(SLC12A1)
BTAX: 128054668(SLC12A1)
ODA: 120852954(SLC12A1)
CCAD: 122443637(SLC12A1)
MBEZ: 129562408(SLC12A1)
SSC: 100154291(SLC12A1)
CFR: 102506351(SLC12A1)
CBAI: 105077003(SLC12A1)
CDK: 105104881(SLC12A1)
VPC: 102526005(SLC12A1)
BACU: 103000967(SLC12A1)
BMUS: 118890326(SLC12A1)
LVE: 103089864(SLC12A1)
OOR: 101272582(SLC12A1)
DLE: 111181623(SLC12A1)
PCAD: 102985214(SLC12A1)
PSIU: 116748489(SLC12A1)
NASI: 112396514(SLC12A1)
ECB: 100055787(SLC12A1) 111767871
EPZ: 103546900(SLC12A1)
EAI: 106838680(SLC12A1)
MYB: 102245756(SLC12A1)
MYD: 102757513(SLC12A1)
MMYO: 118651465(SLC12A1)
MLF: 102432810(SLC12A1)
PKL: 118721688(SLC12A1)
EFUS: 103287405(SLC12A1)
MNA: 107535601(SLC12A1)
DRO: 112311652(SLC12A1)
SHON: 118992594(SLC12A1)
AJM: 119057609(SLC12A1)
PDIC: 114492858(SLC12A1)
PHAS: 123808210(SLC12A1)
MMF: 118629637(SLC12A1)
PPAM: 129063804(SLC12A1)
HAI: 109394446(SLC12A1)
RFQ: 117023534(SLC12A1)
PALE: 102880368(SLC12A1)
PGIG: 120622820(SLC12A1)
PVP: 105288808(SLC12A1)
RAY: 107519962(SLC12A1)
MJV: 108386404(SLC12A1)
TOD: 119238593(SLC12A1)
SARA: 101549641(SLC12A1)
SETR: 126020881(SLC12A1)
LAV: 100658243(SLC12A1)
TMU: 101354966
ETF: 101653685(SLC12A1)
DNM: 101416307(SLC12A1)
MDO: 100025723(SLC12A1)
GAS: 123237955(SLC12A1)
SHR: 100924342(SLC12A1)
AFZ: 127551127
PCW: 110200836(SLC12A1)
OAA: 100090924(SLC12A1)
GGA: 415433(SLC12A1)
PCOC: 116244707(SLC12A1)
MGP: 100550350(SLC12A1)
CJO: 107318746(SLC12A1)
TPAI: 128075311(SLC12A1)
LMUT: 125698397(SLC12A1)
NMEL: 110403706(SLC12A1)
APLA: 101798381(SLC12A1)
ACYG: 106033646(SLC12A1)
CATA: 118251664(SLC12A1)
AFUL: 116493427(SLC12A1)
TGU: 100228327(SLC12A1)
LSR: 110474241(SLC12A1)
SCAN: 103816016(SLC12A1)
PMOA: 120509064(SLC12A1)
OTC: 121343437(SLC12A1)
PRUF: 121354407(SLC12A1)
GFR: 102038152(SLC12A1)
FAB: 101817874(SLC12A1)
OMA: 130257458(SLC12A1)
PHI: 102102494(SLC12A1)
PMAJ: 107209278(SLC12A1)
CCAE: 111934116(SLC12A1)
CCW: 104683999(SLC12A1)
CBRC: 103621256(SLC12A1)
ETL: 114059915(SLC12A1)
ZAB: 102066645(SLC12A1)
ACHL: 103801027(SLC12A1)
SVG: 106851821(SLC12A1)
MMEA: 130575764(SLC12A1)
HRT: 120758539(SLC12A1)
FPG: 101921584(SLC12A1)
FCH: 102059774(SLC12A1)
CLV: 102089395(SLC12A1)
EGZ: 104130915(SLC12A1)
NNI: 104017133(SLC12A1)
PCRI: 104032588(SLC12A1)
PLET: 104620328(SLC12A1)
EHS: 104515413(SLC12A1)
PCAO: 104045654(SLC12A1)
ACUN: 113484102(SLC12A1)
TALA: 104364708(SLC12A1)
PADL: 103922751(SLC12A1)
AFOR: 103896617(SLC12A1)
ACHC: 115340943(SLC12A1)
HALD: 104323501(SLC12A1)
HLE: 104834496(SLC12A1)
AGEN: 126043569
GCL: 127020443
CCRI: 104164661(SLC12A1)
CSTI: 104564212(SLC12A1)
CMAC: 104482445(SLC12A1)
MUI: 104543948(SLC12A1)
BREG: 104632782(SLC12A1)
FGA: 104081059(SLC12A1)
GSTE: 104254673(SLC12A1)
LDI: 104340506(SLC12A1)
MNB: 103771268(SLC12A1)
OHA: 104334593(SLC12A1)
NNT: 104407130(SLC12A1)
SHAB: 115612437(SLC12A1)
DPUB: 104297328(SLC12A1)
PGUU: 104468567(SLC12A1)
ACAR: 104530759(SLC12A1)
CPEA: 104385927(SLC12A1)
AVIT: 104278905(SLC12A1)
CVF: 104287433(SLC12A1)
RTD: 128914779(SLC12A1)
CUCA: 104055731(SLC12A1)
TEO: 104374587(SLC12A1)
BRHI: 104494331(SLC12A1)
AAM: 106496420(SLC12A1)
AROW: 112963467(SLC12A1)
NPD: 112952821(SLC12A1)
TGT: 104571995(SLC12A1)
DNE: 112981424(SLC12A1)
SCAM: 104148262(SLC12A1)
ASN: 102384360(SLC12A1)
AMJ: 106736757(SLC12A1)
CPOO: 109309035(SLC12A1)
GGN: 109288593(SLC12A1)
PSS: 102456510(SLC12A1)
CMY: 102934046(SLC12A1)
CCAY: 125643455(SLC12A1)
DCC: 119862347(SLC12A1)
CPIC: 101948423(SLC12A1)
TST: 117884372(SLC12A1)
CABI: 116814912(SLC12A1)
MRV: 120373381(SLC12A1)
ACS: 100554780(slc12a1)
ASAO: 132762379(SLC12A1)
PVT: 110077257(SLC12A1)
SUND: 121935543(SLC12A1)
PBI: 103059353(SLC12A1)
PMUR: 107287689(SLC12A1)
CTIG: 120315225(SLC12A1)
PGUT: 117675746(SLC12A1)
APRI: 131184611(SLC12A1)
PTEX: 113442188(SLC12A1)
NSS: 113418296(SLC12A1)
VKO: 123027684(SLC12A1)
PMUA: 114584306(SLC12A1)
PRAF: 128401474(SLC12A1)
ZVI: 118092706(SLC12A1)
HCG: 128335213(SLC12A1)
GJA: 107110933(SLC12A1)
STOW: 125446193(SLC12A1)
EMC: 129345316(SLC12A1)
XLA: 101101701(slc12a1.L)
XTR: 100490198(slc12a1)
NPR: 108799219(SLC12A1)
RTEM: 120931332(SLC12A1)
BBUF: 120985827(SLC12A1)
BGAR: 122927625(SLC12A1)
MUO: 115459744(SLC12A1)
GSH: 117348341(SLC12A1)
DRE: 100329975(slc12a1)
SRX: 107739981
SANH: 107681011(slc12a1)
SGH: 107568157
CCAR: 109065746
CAUA: 113061355 113061370 113118040(slc12a1)
CGIB: 127934341 127977562
PTET: 122362967 122363155(slc12a1)
LROH: 127180973(slc12a1)
OMC: 131524321(slc12a1)
PPRM: 120487760(slc12a1)
RKG: 130077532(slc12a1)
MAMB: 125254095(slc12a1)
CIDE: 127499675
MASI: 127417198 127455795
TROS: 130562583(slc12a1)
TDW: 130435485(slc12a1)
MANU: 129419785(slc12a1)
IPU: 108264284
IFU: 128607164(slc12a1)
SMEO: 124395628(slc12a1)
TFD: 113664006(slc12a1)
TVC: 132851544(slc12a1)
AMEX: 103021814(slc12a1)
CMAO: 118803976(slc12a1)
EEE: 113577304(slc12a1)
CHAR: 105889031(slc12a1)
TRU: 101075911(slc12a1)
TFS: 130521894(slc12a1)
TNG: GSTEN00018077G001
LCO: 104935373(slc12a1)
NCC: 104944150(slc12a1)
TBEN: 117471469(slc12a1)
CGOB: 115024888(slc12a1)
PGEO: 117467384(slc12a1)
GACU: 117549394(slc12a1)
EMAC: 134863136(slc12a1)
ELY: 117254915(slc12a1)
EFO: 125904102(slc12a1)
PLEP: 121947138(slc12a1)
SLUC: 116054711(slc12a1)
ECRA: 117949560(slc12a1)
ESP: 116702257(slc12a1)
PFLV: 114566525(slc12a1)
GAT: 120812083(slc12a1)
PPUG: 119227948(slc12a1)
AFB: 129107018(slc12a1)
CLUM: 117750008(slc12a1)
MSAM: 119890206(slc12a1)
SCHU: 122873858(slc12a1)
CUD: 121510510(slc12a1)
ALAT: 119017536(slc12a1)
MZE: 101473081(slc12a1)
ONL: 100695171(slc12a1)
OAU: 116311730(slc12a1)
OLA: 101173045(slc12a1)
OML: 112161093(slc12a1)
CSAI: 133459795(slc12a1)
XMA: 102220049(slc12a1)
XCO: 114143764(slc12a1)
XHE: 116719058(slc12a1)
PRET: 103462078(slc12a1)
PFOR: 103146147(slc12a1)
PLAI: 106935168(slc12a1)
PMEI: 106903741(slc12a1)
GAF: 122841426(slc12a1)
PPRL: 129369414(slc12a1)
CVG: 107085329(slc12a1)
CTUL: 119782429(slc12a1)
GMU: 124867336(slc12a1)
NFU: 107381721(slc12a1)
KMR: 108229397(slc12a1)
ALIM: 106530378(slc12a1)
NWH: 119429461(slc12a1)
AOCE: 111565760(slc12a1)
MCEP: 125005688(slc12a1)
CSEM: 103378836(slc12a1)
POV: 109637281(slc12a1)
SSEN: 122772263(slc12a1)
HHIP: 117754589(slc12a1)
HSP: 118107251(slc12a1)
SMAU: 118302329(slc12a1)
LCF: 108887903
SDU: 111238692(slc12a1)
SLAL: 111654717(slc12a1)
XGL: 120788053(slc12a1)
HCQ: 109525999(slc12a1)
SSCV: 125967572
SBIA: 133498020(slc12a1)
PEE: 133399345(slc12a1)
PTAO: 133467108(slc12a1)
BPEC: 110173055(slc12a1)
MALB: 109963307(slc12a1)
BSPL: 114842853(slc12a1)
SJO: 128363353(slc12a1)
STRU: 115166949 115203356
OTW: 112264243(slc12a1)
OMY: 110506139 110517805
OGO: 124033455(slc12a1)
OKI: 109879007(slc12a1) 116365672
OKE: 118375229 127918384
SNH: 120040018 120042798
CCLU: 121579710 123488615
ELS: 105022666(slc12a1)
SFM: 108940951(slc12a1)
PKI: 111845067(slc12a1)
AANG: 118215764 118226719
LOC: 102691127(slc12a1)
PSPA: 121294777 121299381
ARUT: 117429741 117964332
PSEX: 120539952(slc12a1)
LCM: 102348745(SLC12A1)
CMK: 103172740(slc12a1)
CPLA: 122542462(slc12a1)
HOC: 132834732(slc12a1)
LERI: 129713549(slc12a1)
PMEO: 129598216
PND: Pla175_18230
 » show all
Reference
PMID:12739168
  Authors
Hebert SC, Mount DB, Gamba G
  Title
Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family.
  Journal
Pflugers Arch 447:580-93 (2004)
DOI:10.1007/s00424-003-1066-3
  Sequence
[hsa:6557]

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Gene (1325)   
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