KEGG   ORTHOLOGY: K14454
Entry
K14454                      KO                                     

Name
GOT1
Definition
aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
Pathway
map00220  Arginine biosynthesis
map00250  Alanine, aspartate and glutamate metabolism
map00270  Cysteine and methionine metabolism
map00330  Arginine and proline metabolism
map00350  Tyrosine metabolism
map00360  Phenylalanine metabolism
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map00710  Carbon fixation in photosynthetic organisms
map00950  Isoquinoline alkaloid biosynthesis
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
Module
M00170  C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type
M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00710 Carbon fixation in photosynthetic organisms
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
   00270 Cysteine and methionine metabolism
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
   00220 Arginine biosynthesis
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
   00330 Arginine and proline metabolism
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
   00350 Tyrosine metabolism
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
   00360 Phenylalanine metabolism
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.1  aspartate transaminase
     K14454  GOT1; aspartate aminotransferase, cytoplasmic
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class I
   K14454  GOT1; aspartate aminotransferase, cytoplasmic
Membrane trafficking [BR:ko04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    K14454  GOT1; aspartate aminotransferase, cytoplasmic
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K14454  GOT1; aspartate aminotransferase, cytoplasmic
  Exosomal proteins of other body fluids (saliva and urine)
   K14454  GOT1; aspartate aminotransferase, cytoplasmic
Other DBs
RN: R00355 R00694 R00734 R00896 R02433 R02619 R05052
GO: 0004069
Genes
HSA: 137362(GOT1L1) 2805(GOT1)
PTR: 450664(GOT1) 747942(GOT1L1)
PPS: 100973276(GOT1L1) 100991554(GOT1)
GGO: 101131156(GOT1) 101148329(GOT1L1)
PON: 100173864(GOT1) 100454079(GOT1L1)
NLE: 100596785(GOT1) 100602424(GOT1L1)
MCC: 703277(GOT1L1) 708434(GOT1)
MCF: 101865666(GOT1) 102142672(GOT1L1)
CSAB: 103215634(GOT1L1) 103216369(GOT1)
CATY: 105581817(GOT1) 105590786(GOT1L1)
PANU: 101003411(GOT1L1) 101023775(GOT1)
RRO: 104656457(GOT1) 104679652 115899716(GOT1L1)
RBB: 108513570(GOT1L1) 108534958(GOT1)
TFN: 117068718(GOT1) 117092261(GOT1L1)
PTEH: 111538782(GOT1) 111544171(GOT1L1)
CJC: 100386102(GOT1L1) 100409421(GOT1)
SBQ: 101028876(GOT1L1) 101048049(GOT1)
MMUR: 105870385(GOT1L1) 105873330(GOT1)
MMU: 14718(Got1) 76615(Got1l1)
MCAL: 110285643(Got1) 110300511(Got1l1)
MPAH: 110321548(Got1) 110337126(Got1l1)
RNO: 24401(Got1)
MCOC: 116071270(Got1l1) 116103867(Got1)
MUN: 110550194(Got1l1) 110552969(Got1)
CGE: 100750547(Got1l1) 100762297(Got1)
PLEU: 114686800(Got1l1) 114706449(Got1)
NGI: 103724470(Got1l1) 103728564 103733179(Got1)
HGL: 101713030(Got1) 101721522(Got1l1)
CCAN: 109675222(Got1l1) 109697528(Got1)
OCU: 100339345(GOT1L1) 100340431(GOT1)
TUP: 102489665(GOT1L1) 102497034(GOT1)
CFA: 475591(GOT1L1) 486834(GOT1)
VVP: 112914709(GOT1) 112916125(GOT1L1)
VLG: 121484366(GOT1) 121487018 121489476(GOT1L1)
AML: 100465209(GOT1) 100469239(GOT1L1)
UMR: 103659119(GOT1L1) 103675855(GOT1)
UAH: 113251814(GOT1) 113261997(GOT1L1)
ORO: 101385088(GOT1) 101386147(GOT1L1)
ELK: 111144929
MPUF: 101684305(GOT1)
EJU: 114202232(GOT1L1) 114205315(GOT1)
MLX: 118009968(GOT1L1) 118024778(GOT1)
FCA: 101085155(GOT1) 101099457(GOT1L1)
PTG: 102951839(GOT1L1) 102971975(GOT1)
PPAD: 109262315(GOT1L1) 109272750(GOT1)
AJU: 106966849(GOT1) 106978384(GOT1L1)
HHV: 120224806 120238682(GOT1L1)
BTA: 281206(GOT1) 507913(GOT1L1)
BOM: 102278649(GOT1L1) 102284586(GOT1)
BIU: 109553071(GOT1) 109553265(GOT1L1)
BBUB: 102403169(GOT1) 102410683(GOT1L1)
CHX: 100861063(GOT1) 102186370(GOT1L1)
OAS: 101111158(GOT1L1) 101118747(GOT1)
ODA: 120865654(GOT1L1) 120873518(GOT1)
SSC: 110257165(GOT1L1) 396967(GOT1)
CFR: 102517386(GOT1) 102520685(GOT1L1)
CDK: 105084303(GOT1) 105089941(GOT1L1)
BACU: 102998009(GOT1) 103017775(GOT1L1)
LVE: 103074183(GOT1L1) 103081202(GOT1)
OOR: 101276910(GOT1L1) 101277576(GOT1)
DLE: 111172411(GOT1) 111173616(GOT1L1)
PCAD: 102989668(GOT1)
ECB: 100059580(GOT1L1) 100060793(GOT1)
EPZ: 103557881 103567292(GOT1L1)
EAI: 106837693(GOT1L1) 106846693(GOT1)
MYB: 102238759(GOT1) 102249560(GOT1L1)
MYD: 102758930(GOT1L1) 102763852(GOT1)
MMYO: 118649561(GOT1L1) 118669872(GOT1)
MNA: 107535444(GOT1L1) 107536783 107542649(GOT1)
HAI: 109379693(GOT1) 109393578(GOT1L1)
DRO: 112300403(GOT1) 112306693(GOT1L1)
SHON: 118990258(GOT1) 118993168(GOT1L1)
AJM: 119044550(GOT1) 119065022(GOT1L1)
MMF: 118622323(GOT1L1) 118632559(GOT1)
PALE: 102880173(GOT1L1) 102881255(GOT1)
RAY: 107515948(GOT1L1) 107520390(GOT1)
MJV: 108409138(GOT1L1) 108410283(GOT1)
TOD: 119233613(GOT1) 119235072 119257808(GOT1L1)
LAV: 100666637(GOT1) 100674813(GOT1L1)
MDO: 100020894(GOT1) 100032942(GOT1L1)
SHR: 100917383(GOT1L1) 100919097(GOT1)
PCW: 110207741(GOT1L1) 110215368(GOT1)
OAA: 100076641(GOT1) 100090021(GOT1L1)
GGA: 396261(GOT1)
PCOC: 116231728(GOT1)
MGP: 100546713(GOT1)
CJO: 107316032(GOT1)
NMEL: 110400149(GOT1)
APLA: 101803039(GOT1)
ACYG: 106037130(GOT1)
TGU: 100218937(GOT1)
LSR: 110473684(GOT1)
SCAN: 103814164(GOT1)
PMOA: 120502110(GOT1)
GFR: 102042885(GOT1)
FAB: 101821129(GOT1)
PHI: 102111515(GOT1)
PMAJ: 107207144(GOT1)
CCAE: 111930931(GOT1)
CCW: 104697906(GOT1)
ETL: 114070981(GOT1)
FPG: 101916769(GOT1)
FCH: 102058998(GOT1)
CLV: 102096743(GOT1)
EGZ: 104129079(GOT1)
NNI: 104013747(GOT1)
ACUN: 113481762(GOT1)
PADL: 103916342(GOT1)
AAM: 106494692(GOT1)
ASN: 102373139(GOT1L1) 102379628(GOT1)
AMJ: 102566110(GOT1) 102574829(GOT1L1)
CPOO: 109323844(GOT1)
GGN: 109287161(GOT1) 109295466(GOT1L1)
PSS: 102459319(GOT1) 102462952
CMY: 102930536(GOT1L1) 102946627(GOT1)
CPIC: 101946274(GOT1L1) 101951211(GOT1)
TST: 117871776(GOT1L1) 117880213(GOT1)
CABI: 116815624(GOT1) 116828575
ACS: 100554156(got1) 100556143(got1l1)
PVT: 110075176(GOT1L1) 110084029(GOT1)
PBI: 103056766(GOT1) 103063653(GOT1L1)
PMUR: 107287734(GOT1) 107296750(GOT1L1)
TSR: 106537844(GOT1)
PGUT: 117676958(GOT1L1) 117678579(GOT1)
ZVI: 118093813(GOT1) 118097315(GOT1L1)
GJA: 107108160(GOT1L1) 107121133(GOT1)
XLA: 108697935 380235(got1.S)
XTR: 407943(got1)
NPR: 108788250(GOT1) 108802063
DRE: 406330(got1) 791730(got1l1)
IPU: 100304844(got1) 108265709
PHYP: 113533217 113544591(got1)
AMEX: 103034654(got1) 103047857
EEE: 113578765 113585466(got1)
TRU: 101067450(got1) 101072642
NCC: 104955140(got1) 104963284
ELY: 117248319(got1) 117251982(got1l1) 117255221
PLEP: 121944956(got1l1) 121954623(got1) 121966597
SLUC: 116049894 116053895(got1l1) 116053917(got1)
ECRA: 117944248(got1l1) 117960138(got1) 117962108
GAT: 120813083 120820706(got1) 120830602(got1l1)
MSAM: 119891996(got1l1) 119898188 119917270(got1)
CUD: 121508588 121509933(got1l1) 121510606(got1)
OAU: 116310242(got1l1) 116315580 116335144(got1)
OLA: 101156301 101163996(got1)
OML: 112157276 112161735(got1)
XMA: 102228200(got1) 102231045
XCO: 114138323(got1) 114145092
XHE: 116713456(got1) 116720250
PRET: 103470098 103476907(got1)
CVG: 107081991 107091903(got1)
CTUL: 119773780 119790716(got1)
NFU: 107375677(got1) 107382402
KMR: 108234102(got1) 108247449
ALIM: 106528295(got1)
XGL: 120796870(got1) 120800162 120804963(got1l1)
HCQ: 109511472 109512731(got1)
ELS: 105006879 105021383(got1)
SFM: 108942587(got1)
PKI: 111838409 111848455(got1)
LOC: 102689506 102695390(got1)
PSPA: 121302475(got1l1) 121321912(got1) 121325784
LCM: 102362598(GOT1L1) 102366803(GOT1)
CMK: 103188918(got1) 103190261
RTP: 109922767(got1) 109925736
BFO: 118413807
CIN: 100184965
SCLV: 120347190
SPU: 589279
APLC: 110977055
SKO: 100371200
DME: Dmel_CG8430(Got1)
DER: 6548929
DSE: 6609379
DSI: Dsimw501_GD11164(Dsim_GD11164)
DAN: 6494632
DSR: 110189258
DWI: 6640495
DVI: 6627186
MDE: 101892419
LCQ: 111690862
ACOZ: 120951575
AARA: 120893536
AAG: 5576532
AALB: 109423544
CPII: 120428729
AME: 727622
ACER: 107997944
BIM: 100748545
BTER: 100649476
CCAL: 108630606
OBB: 114873120
MGEN: 117219728
NMEA: 116431427
CGIG: 122394873
SOC: 105200828
MPHA: 105834039
AEC: 105148219
ACEP: 105624361
PBAR: 105431655
VEM: 105560396
HST: 105184626
DQU: 106741771
CFO: 105251033
LHU: 105677263
PGC: 109855172
PCF: 106788930
NVI: 100120655
CSOL: 105361848
MDL: 103573801
TCA: 658043
NVL: 108563539
BMOR: 101736083
BMAN: 114249957
MSEX: 115448797
BANY: 112058408
PPOT: 106109929
PXU: 106114687
PRAP: 110992304
HAW: 110383373
TNL: 113492937
PXY: 105385171
DNX: 107173437
DCI: 103512360
CLEC: 106662126
NLU: 111053298
FCD: 110860549
PVM: 113830463
HAME: 121870804
EAF: 111701246
DSV: 119459165
RMP: 119175847
VDE: 111243418
VJA: 111264668
TUT: 107362750
DPTE: 113798183
CEL: CELE_T01C8.5(got-1.2)
BMY: BM_BM5467(Bma-got-1.2)
PCAN: 112564342
BGT: 106058121
GAE: 121384155
CRG: 105330192
MYI: 110451694
OBI: 106871193
LAK: 106176584
EGL: EGR_00314
NVE: 5505584
EPA: 110238544
ATEN: 116291719
ADF: 107342068
AMIL: 114967977
PDAM: 113669683
SPIS: 111326311
HMG: 100198597
ATH: AT1G62800(ASP4) AT5G11520(ASP3) AT5G19550(ASP2)
CPAP: 110812471
GMX: 547509(AAT)
VRA: 106760737
VAR: 108321846
VUN: 114164074
CCAJ: 109800915
APRC: 113864525
CAM: 101506203
LJA: Lj1g3v2050900.1(Lj1g3v2050900.1)
ADU: 107470766
AIP: 107622437
LANG: 109344204(AAT-P1)
PXB: 103957474
CSV: 101213892
CMO: 103503710
BHJ: 120085573
MCHA: 111005162
JCU: 105637736
CANN: 107839125
CSIN: 114321793
MING: 122061623
NCOL: 116255635
OSA: 4325621
DOSA: Os01t0760600-01(Os01g0760600)
OBR: 102702612
BDI: 100824909
ATS: 109753696
SBI: 110433801
ZMA: 100273311(pco118382)
SITA: 101771115
PHAI: 112893070
PDA: 103706860
EGU: 105044252
DCT: 110109088
PEQ: 110020645
ATR: 18426621
PPP: 112274424
VCN: VOLCADRAFT_82929(ast1)
MNG: MNEG_3068
APRO: F751_0301
SCE: YLR027C(AAT2)
ERC: Ecym_6087
KMX: KLMA_40083(AAT2)
NCS: NCAS_0A04170(NCAS0A04170)
NDI: NDAI_0E01910(NDAI0E01910)
TPF: TPHA_0G02780(TPHA0G02780)
TBL: TBLA_0B09330(TBLA0B09330)
TDL: TDEL_0A01940(TDEL0A01940)
KAF: KAFR_0D02850(KAFR0D02850)
PIC: PICST_51039(AAT22) PICST_66059(AAT2)
NCR: NCU07941
NTE: NEUTE1DRAFT78242(NEUTE1DRAFT_78242)
MAW: MAC_00667
MAJ: MAA_06467
CMT: CCM_05388
MBE: MBM_00726
ANG: ANI_1_1196084(An09g02390) ANI_1_126034(An03g01120) ANI_1_772144(An16g05570) ANI_1_956104(An12g07870)
PNO: SNOG_08796(SNOG_08795) SNOG_13594(SNOG_13593)
PTE: PTT_08812
ABP: AGABI1DRAFT111350(AGABI1DRAFT_111350)
ABV: AGABI2DRAFT190572(AGABI2DRAFT_190572)
MGL: MGL_3528
MRT: MRET_0908
DDI: DDB_G0282493(aatB)
DFA: DFA_08693(aatB)
TAN: TA12970
TPV: TP02_0046
BBO: BBOV_III010960(17.m07944)
 » show all
Reference
  Authors
D'Aniello A, Fisher G, Migliaccio N, Cammisa G, D'Aniello E, Spinelli P
  Title
Amino acids and transaminases activity in ventricular CSF and in brain of normal and Alzheimer patients.
  Journal
Neurosci Lett 388:49-53 (2005)
DOI:10.1016/j.neulet.2005.06.030
  Sequence
[hsa:2805]

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