KEGG ORTHOLOGY: K15194

ORTHOLOGY: K15194

Entry

K15194                      KO

Symbol

AFF2

Name

AF4/FMR2 family member 2

Disease

H00480

X-linked intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery
    K15194  AFF2; AF4/FMR2 family member 2
Transcription machinery [BR:ko03021]
Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Others
     K15194  AFF2; AF4/FMR2 family member 2

Other DBs

GO:

0043484

Genes

HSA:	2334(AFF2)

PTR:	450122(AFF2)

PPS:	100980215(AFF2)

GGO:	101147147(AFF2)

PON:	100434131(AFF2)

NLE:	100580859(AFF2)

HMH:	116811218(AFF2)

MCC:	700758(AFF2)

MCF:	101925439(AFF2)

MTHB:

126945284

MNI:	105485067(AFF2)

CSAB:

103232713(AFF2)

CATY:

105595591(AFF2)

PANU:

101007925(AFF2)

TGE:	112615477(AFF2)

MLEU:

105532909(AFF2)

RRO:	104680794(AFF2)

RBB:	108536230(AFF2)

TFN:	117077203(AFF2)

PTEH:

111536370(AFF2)

CANG:

105503390(AFF2)

CJC:	100385337(AFF2)

SBQ:	101028459(AFF2)

CIMI:

108292763(AFF2)

CSYR:

103260894(AFF2)

MMUR:

105858392(AFF2)

PCOQ:

105827229(AFF2)

OGA:	100964644(AFF2)

MMU:	14266(Aff2)

MCAL:

110286563(Aff2)

MPAH:

110313445(Aff2)

RNO:	293922(Aff2)

MCOC:

116102819(Aff2)

ANU:	117694845(Aff2)

MUN:	110541847(Aff2)

CGE:	100756662(Aff2)

MAUA:

101832588(Aff2)

PROB:

127218174(Aff2)

PLEU:

114682011(Aff2)

MORG:

121440230 121440444

MFOT:

126492689

AAMP:

119804501(Aff2)

NGI:	103737441(Aff2)

HGL:	101710218(Aff2)

CPOC:

100717526(Aff2)

CCAN:

109703021(Aff2)

DORD:

105992863(Aff2)

DSP:	122108487(Aff2)

PLOP:

125344157(Aff2)

NCAR:

124972138

MMMA:

107152524(Aff2)

OCU:

100356143

OPI:	101532455(AFF2)

TUP:	102489668(AFF2)

GVR:	103605567(AFF2)

CFA:	492193(AFF2)

CLUD:

112668453(AFF2)

VVP:	112927678(AFF2)

VLG:	121482382(AFF2)

NPO:	129518122(AFF2)

AML:	100471266(AFF2)

UMR:	103662557(AFF2)

UAH:	113241893(AFF2)

UAR:	123786499(AFF2)

ELK:

111158947

LLV:

125091870

MPUF:

101694121(AFF2)

MNP:	132007297(AFF2)

MLK:	131821608(AFF2)

NVS:	122896895(AFF2)

ORO:	101383447(AFF2)

EJU:	114199025(AFF2)

ZCA:	113930543(AFF2)

MLX:	118008269(AFF2)

NSU:	110573890(AFF2)

FCA:	101092251(AFF2)

PYU:	121025127(AFF2)

PCOO:

112871124(AFF2)

PBG:	122477544(AFF2)

PVIV:

125157618(AFF2)

LRUF:

124525733

PTG:	102968618(AFF2)

PPAD:

109258695(AFF2)

PUC:

125932039

AJU:

106973030

HHV:	120247925(AFF2)

BTA:	522215(AFF2)

BOM:	102286988(AFF2)

BIU:	109554783(AFF2)

BBUB:

102411521(AFF2)

CHX:	102189103(AFF2)

OAS:	101116804(AFF2)

BTAX:

128069430(AFF2)

ODA:	120881564(AFF2)

CCAD:

122434716(AFF2)

MBEZ:

129564268(AFF2)

SSC:	100512515(AFF2)

CFR:	102509248(AFF2)

CBAI:

105064975(AFF2)

CDK:	105104104(AFF2)

VPC:	102525891(AFF2)

BACU:

103020887(AFF2)

BMUS:

118889026(AFF2)

LVE:

103078767

OOR:	101289137(AFF2)

DLE:	111167836(AFF2)

PCAD:

102984289(AFF2)

PSIU:

116747893(AFF2)

NASI:

112399710(AFF2)

ECB:	100055437(AFF2)

EPZ:

103565496

EAI:	106846165(AFF2)

MYB:	102250337(AFF2)

MYD:	102771874(AFF2)

MMYO:

118654524(AFF2)

MLF:	102440982(AFF2)

PKL:	118722120(AFF2)

EFUS:

103302022(AFF2)

MNA:	107530069(AFF2)

DRO:	112296263(AFF2)

SHON:

118996052(AFF2)

PDIC:

114505746(AFF2)

PHAS:

123807034(AFF2)

MMF:	118635372(AFF2)

PPAM:

129082178(AFF2)

HAI:	109388977(AFF2)

RFQ:	117028146(AFF2)

PALE:

102893337(AFF2)

PGIG:

120608681(AFF2)

PVP:	105309495(AFF2)

RAY:	107502398(AFF2)

MJV:	108383405(AFF2)

TOD:	119245843(AFF2)

SARA:

101539057(AFF2)

SETR:

125999419(AFF2)

LAV:	100668671(AFF2)

TMU:

101357389

ETF:	101641171(AFF2)

DNM:	101444185(AFF2)

MDO:	100025041(AFF2)

GAS:	123253339(AFF2)

SHR:	100932146(AFF2)

AFZ:

127542919

PCW:	110199817(AFF2)

OAA:	100081702(AFF2)

GGA:	422394(AFF2)

PCOC:

116234853(AFF2)

MGP:

100548706

CJO:	107312939(AFF2)

TPAI:

128076225(AFF2)

LMUT:

125699894(AFF2)

NMEL:

110403075(AFF2)

APLA:

101789773(AFF2)

ACYG:

106037694(AFF2)

CATA:

118245346(AFF2)

AFUL:

116494304(AFF2)

TGU:	100218859(AFF2)

LSR:	110480128(AFF2)

SCAN:

103816514(AFF2)

PMOA:

120506197(AFF2)

OTC:	121331783(AFF2)

PRUF:

121363089(AFF2)

GFR:	102042557(AFF2)

FAB:	101810175(AFF2)

OMA:	130253056(AFF2)

PHI:

102104789

PMAJ:

107203853(AFF2)

CCAE:

111928511(AFF2)

CCW:	104691673(AFF2)

CBRC:

103617882(AFF2)

ETL:	114056732(AFF2)

ZAB:	102064857(AFF2)

ACHL:

103799545(AFF2)

SVG:	106856288(AFF2)

MMEA:

130577114(AFF2)

HRT:	120761955(AFF2)

FPG:	101917816(AFF2)

FCH:	102056651(AFF2)

CLV:	102086189(AFF2)

EGZ:	104124052(AFF2)

NNI:	104019095(AFF2)

PCRI:

104034843(AFF2)

PLET:

104622641(AFF2)

PCAO:

104050529(AFF2)

ACUN:

113479942(AFF2)

TALA:

104360475(AFF2)

PADL:

103923146(AFF2)

AFOR:

103895710(AFF2)

ACHC:

115333538(AFF2)

HALD:

104319425(AFF2)

HLE:	104832769(AFF2)

AGEN:

126050279

GCL:

127019546

CSTI:

104558167(AFF2)

CMAC:

104481845

MUI:	104535828(AFF2)

BREG:

104644159(AFF2)

FGA:	104075667(AFF2)

GSTE:

104263042(AFF2)

LDI:	104350745(AFF2)

MNB:	103773513(AFF2)

OHA:	104329573(AFF2)

NNT:	104412694(AFF2)

SHAB:

115613284(AFF2)

DPUB:

104301196(AFF2)

PGUU:

104470912(AFF2)

ACAR:

104527479(AFF2)

CPEA:

104388345(AFF2)

AVIT:

104273038(AFF2)

CVF:	104290240(AFF2)

RTD:	128914684(AFF2)

CUCA:

104063100(AFF2)

TEO:

104373028

BRHI:

104490835(AFF2)

AAM:	106487523(AFF2)

AROW:

112972791(AFF2)

NPD:	112947115(AFF2)

TGT:	104570893(AFF2)

DNE:	112986834(AFF2)

SCAM:

104142205(AFF2)

ASN:	102375951(AFF2)

AMJ:	102572904(AFF2)

CPOO:

109313626(AFF2)

GGN:	109300822(AFF2)

PSS:	102447647(AFF2)

CMY:	102939061(AFF2)

CCAY:

125642328(AFF2)

DCC:	119861185(AFF2)

CPIC:

101934244(AFF2)

TST:	117882640(AFF2)

CABI:

116824493(AFF2)

MRV:	120371861(AFF2)

ACS:	100566047(aff2)

ASAO:

132763224(AFF2)

PVT:	110082977(AFF2)

SUND:

121936305(AFF2)

PBI:	103053729(AFF2)

PMUR:

107291667(AFF2)

CTIG:

120313147(AFF2)

PGUT:

117677971(AFF2)

APRI:

131204997(AFF2)

PTEX:

113446777(AFF2)

NSS:	113422463(AFF2)

VKO:	123021901(AFF2)

PMUA:

114588805(AFF2)

PRAF:

128407003(AFF2)

ZVI:	118084006(AFF2)

HCG:	128335503(AFF2)

GJA:	107107991(AFF2)

STOW:

125443121(AFF2)

EMC:	129340932(AFF2)

XLA:	108698911(aff2.L) 108700123(aff2.S)

XTR:	100487096(aff2)

NPR:	108783895(AFF2)

RTEM:

120913663(AFF2)

BBUF:

121009226(AFF2)

BGAR:

122946858(AFF2)

MUO:	115474410(AFF2)

GSH:	117360905(AFF2)

DRE:	100330019(aff2)

SRX:	107742425 107754505

SANH:

107665257 107703651

SGH:	107557674 107588359(aff2)

CCAR:

109062580 109102022

CAUA:

113069594 113114350

CGIB:

127971119 128026834

PTET:

122358036(aff2)

LROH:

127176617(aff2)

OMC:	131553382(aff2)

PPRM:

120460843(aff2)

RKG:	130085451(aff2)

MAMB:

125258940(aff2)

CIDE:

127494124

MASI:

127412578 127417722

TROS:

130563652(aff2)

TDW:	130437994(aff2)

MANU:

129421932(aff2)

IPU:

108269128

IFU:	128611850(aff2)

PHYP:

113542727(aff2)

SMEO:

124386339(aff2)

TFD:	113647735(aff2)

TVC:	132856020(aff2)

AMEX:

103037209(aff2)

CMAO:

118807067(aff2)

EEE:	113572505(aff2)

LCO:	109137633(aff2)

NCC:

104948379

TBEN:

117474984(aff2)

CGOB:

115014562(aff2)

GACU:

117546979

EMAC:

134859932(aff2)

ELY:	117260813(aff2) 117260814

EFO:	125894447(aff2)

PLEP:

121948389(aff2)

SLUC:

116036544(aff2)

ECRA:

117951577(aff2)

ESP:	116685922(aff2)

PFLV:

114562461

GAT:	120817646(aff2)

PPUG:

119210277(aff2)

AFB:	129090523(aff2)

CLUM:

117737909(aff2)

PSWI:

130210098(aff2)

MSAM:

119888201(aff2)

SCHU:

122879858(aff2)

CUD:	121516843(aff2)

ALAT:

119007794(aff2)

MZE:	101467317(aff2)

ONL:	100701573(aff2)

OAU:	116328152(aff2)

OLA:	101157068(aff2)

OML:	112153252(aff2)

CSAI:

133447266(aff2)

XMA:	102225237(aff2)

XCO:	114139227(aff2)

XHE:	116714392(aff2)

PRET:

103471070

PFOR:

103149315 103149317

PLAI:

106957946(aff2)

PMEI:

106928922(aff2)

GAF:	122837201(aff2)

PPRL:

129362531(aff2)

CVG:

107093840

CTUL:

119797264(aff2)

GMU:	124860356(aff2)

NFU:	107375231(aff2)

KMR:	108240017(aff2)

ALIM:

106531620

AOCE:

111582598(aff2)

MCEP:

125007823(aff2)

CSEM:

103391271

POV:	109638079(aff2)

SSEN:

122778526(aff2)

HHIP:

117769231(aff2)

HSP:	118112666(aff2)

SMAU:

118319744(aff2)

LCF:

108878932

SDU:	111226780(aff2)

SLAL:

111646516(aff2)

XGL:

120785812

HCQ:	109524327(aff2)

SSCV:

125977382

SBIA:

133508343(aff2)

PEE:	133407913(aff2)

PTAO:

133484694(aff2)

BPEC:

110172170

MALB:

109957562(aff2)

BSPL:

114863932(aff2)

SJO:	128363094(aff2)

SASA:

106604958 106611959

STRU:

115175045 115205036

OTW:	112220462 112257031

OMY:	110488546 110504399

OGO:	123993192 124010642(aff2)

ONE:	115129141 115130020

OKI:	109905938 109910096

OKE:	118375083 118376069(aff2)

SALP:

111965337(aff2)

SNH:	120047091 120062162

CCLU:

121545505 121585607

ELS:	105027488(aff2)

SFM:	108923127(aff2) 108931053

PKI:	111848132(aff2)

AANG:

118223050(aff2) 118234858

LOC:	102690942(aff2)

PSPA:

121295268 121318970(aff2)

ARUT:

117412379 117430676

PSEX:

120538215

LCM:	102347784(AFF2)

CMK:	103178247(aff2)

CPLA:

122557435(aff2)

HOC:	132820358(aff2)

LERI:

129702284(aff2)

PMRN:

116943533

LRJ:

133350081

DME:	Dmel_CG8817(lilli)

DER:	26526948 6541908

DSE:

6613175

DSI:	Dsimw501_GD23194(Dsim_GD23194)

DYA:	Dyak_GE18192

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11857

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

MDE:	101892616 109614186

SCAC:

LCQ:

LSQ:

AGA:

ACOZ:

AARA:

ASTE:

AAG:

AALB:

CQU:	CpipJ_CPIJ000396

CPII:

CNS:

BCOO:

ALAB:

BBIF:

BVK:

BVAN:

BPYO:

CGIG:

PFUC:

VPS:

TPRE:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

CSET:

AGB:

LDC:

APLN:

PPYR:

HHAL:

FOC:

TPAL:

CSEC:

DMK:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

RSAN:

RMP:

SDM:	118198324 118198679

PMAX:

117329620

» show all

Reference

PMID:21330300

Authors

Melko M, Douguet D, Bensaid M, Zongaro S, Verheggen C, Gecz J, Bardoni B

Title

Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.

Journal

Hum Mol Genet 20:1873-85 (2011)
DOI:10.1093/hmg/ddr069

Sequence

[hsa:2334]

Reference

PMID:11171403

Authors

Wittwer F, van der Straten A, Keleman K, Dickson BJ, Hafen E

Title

Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth.

Journal

Development 128:791-800 (2001)

Sequence

[dme:Dmel_CG8817]

Reference

PMID:19136466

Authors

Bensaid M, Melko M, Bechara EG, Davidovic L, Berretta A, Catania MV, Gecz J, Lalli E, Bardoni B

Title

FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure.

Journal

Nucleic Acids Res 37:1269-79 (2009)
DOI:10.1093/nar/gkn1058

Sequence

[hsa:2334] [mmu:14266]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (898)   
   KEGG GENES (470)   
   KEGG MGENES (314)   
   RefGene (111)   
   OC (3)   
Literature (3)   
   PubMed (3)   
All databases (905)   

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