KEGG   ORTHOLOGY: K15423Help
Entry
K15423                      KO                                     

Name
PPP4C
Definition
serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
Pathway
ko04922  Glucagon signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-4
    Catalytic subunits
     K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    Protein phosphatase 4
     K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit
BRITE hierarchy
Other DBs
COG: COG0639
GO: 0004722
Genes
HSA: 5531(PPP4C)
PTR: 739184(PPP4C)
PPS: 100995699(PPP4C)
GGO: 101130000(PPP4C)
PON: 100173513(PPP4C)
NLE: 100582479(PPP4C)
MCC: 708510(PPP4C)
MCF: 102138118(PPP4C)
CSAB: 103230568(PPP4C)
RRO: 104681210(PPP4C)
CJC: 100393931(PPP4C)
SBQ: 101037597(PPP4C)
MMU: 56420(Ppp4c)
MCAL: 110297622(Ppp4c)
MPAH: 110317474(Ppp4c)
RNO: 171366(Ppp4c)
MUN: 110547996(Ppp4c)
CGE: 100771425(Ppp4c)
NGI: 103726386(Ppp4c)
HGL: 101701412(Ppp4c)
CCAN: 109683240(Ppp4c)
OCU: 100009163(PPP4C)
TUP: 102488505(PPP4C)
CFA: 489947(PPP4C)
VVP: 112929205(PPP4C)
AML: 100478357(PPP4C)
UMR: 103657830(PPP4C)
UAH: 113267651(PPP4C)
ORO: 101384774(PPP4C)
ELK: 111162177
FCA: 101101530(PPP4C)
PTG: 102954414(PPP4C)
PPAD: 109261349(PPP4C)
AJU: 106966830(PPP4C)
BTA: 540398(PPP4C)
BOM: 102271057(PPP4C)
BIU: 109578623(PPP4C)
BBUB: 102401363(PPP4C)
CHX: 102189090(PPP4C)
OAS: 101115751(PPP4C)
SSC: 110260085(PPP4C)
CFR: 102505193(PPP4C)
CDK: 105102765(PPP4C)
BACU: 103004443(PPP4C)
LVE: 103074202(PPP4C)
OOR: 101269372(PPP4C)
DLE: 111182179(PPP4C)
PCAD: 102985887(PPP4C)
ECB: 100064118(PPP4C)
EPZ: 103547184(PPP4C)
EAI: 106845628(PPP4C)
MYB: 102260582(PPP4C)
MYD: 102772871 102773969(PPP4C)
MNA: 107541493(PPP4C)
HAI: 109385993(PPP4C)
DRO: 112304775(PPP4C)
PALE: 102891141(PPP4C)
RAY: 107515840(PPP4C)
MJV: 108398467(PPP4C)
LAV: 100655012(PPP4C)
TMU: 101341687
MDO: 100012739(PPP4C)
SHR: 100933379(PPP4C)
PCW: 110221922(PPP4C)
OAA: 103167811(PPP4C)
GGA: 101748916
CJO: 107307255
ACYG: 106029370(PPP4C)
TGU: 115497503(PPP4C)
SCAN: 103824713
PHI: 102100458(PPP4C)
PMAJ: 107199157(PPP4C)
CCAE: 111933193(PPP4C)
FPG: 106113024(PPP4C)
FCH: 102048924(PPP4C)
NNI: 104015357(PPP4C)
PADL: 103925596
AAM: 106482275
ASN: 102381042(PPP4C)
AMJ: 102564643(PPP4C)
PSS: 102449631(PPP4C)
CMY: 102934151
CPIC: 101941549(PPP4C)
ACS: 100557380(ppp4c)
PVT: 110081789(PPP4C)
PBI: 103060275(PPP4C)
PMUA: 114582023(PPP4C)
GJA: 107117422(PPP4C)
XLA: 108703929 432334(ppp4c.S)
XTR: 394540(ppp4c)
NPR: 108789193(PPP4C)
DRE: 100003080(ppp4ca) 562705(ppp4cb)
IPU: 108273647(ppp4c)
PHYP: 113527615(ppp4c)
AMEX: 103024225(ppp4c)
EEE: 113587520(ppp4c)
TRU: 101074113(ppp4c)
LCO: 104935244(ppp4c)
NCC: 104954908(ppp4c)
MZE: 101479584(ppp4c)
ONL: 100700281(ppp4c)
OLA: 101159020(ppp4c)
XMA: 102220979(ppp4c)
XCO: 114147615(ppp4c)
PRET: 103468183(ppp4c)
CVG: 107104027(ppp4c)
NFU: 107391597(ppp4c)
KMR: 108248186(ppp4c)
ALIM: 106528998(ppp4c)
AOCE: 111578007(ppp4c)
CSEM: 103393586(ppp4c)
POV: 109642853(ppp4c)
LCF: 108898479(ppp4c)
SDU: 111217459(ppp4c)
SLAL: 111655966 111669754(ppp4c)
HCQ: 109532556(ppp4c)
BPEC: 110162483(ppp4c)
MALB: 109964755(ppp4c)
OTW: 112261521(ppp4c) 112261713
SFM: 108933022(ppp4c)
PKI: 111835823(ppp4c)
LCM: 102354103(PPP4C)
CMK: 103184800(ppp4c)
CIN: 100178929
SPU: 594644
APLC: 110980730
SKO: 100372035
DME: Dmel_CG11597(CG11597) Dmel_CG32505(Pp4-19C)
DSI: Dsimw501_GD15536(Dsim_GD15536) Dsimw501_GD27970(Dsim_GD27970)
DPE: 6599926
DWI: 6648627
DAZ: 108620176
DNV: 108657207
DHE: 111593632
MDE: 101888621
AAG: 5563955
AME: 552290
BIM: 100748858
BTER: 100649716
CCAL: 108633140
OBB: 114873883
SOC: 105207716
MPHA: 105836622
AEC: 105149057
ACEP: 105622973
PBAR: 105434079
VEM: 105570468
HST: 105182400
DQU: 106743719
CFO: 105251844
LHU: 105673124
PGC: 109851643
OBO: 105275704
PCF: 106784242
NVI: 100116897
CSOL: 105360164
MDL: 103569629
TCA: 661599
DPA: 109544228
ATD: 109597805
NVL: 108565067
BMOR: 101742306
BMAN: 114252823
PMAC: 106709869
PRAP: 110991433
HAW: 110370777
TNL: 113503175
AGS: 114123145
BTAB: 109042725
ZNE: 110832746
FCD: 110860705
TUT: 107367216
PTEP: 107449140
CEL: CELE_Y49E10.3(pph-4.2) CELE_Y75B8A.30(pph-4.1)
CBR: CBG11776(Cbr-pph-4.1)
BMY: Bm1_28355
PCAN: 112562983
MYI: 110461331
OBI: 106872326
SHX: MS3_06743
EGL: EGR_00833
EPA: 110252260
ADF: 107347747
AMIL: 114960216
PDAM: 113667983
SPIS: 111326107
DGT: 114520566
HMG: 100200590
AQU: 100631736
ATH: AT4G26720(PPX1) AT5G55260(PPX2) AT5G63870(PP7)
CRB: 17879909
CPAP: 110820748
CIT: 102608319
TCC: 18593416
EGR: 104450269
VRA: 106765098
VAR: 108338468
VUN: 114194665
CCAJ: 109805806
CAM: 101488931
LJA: Lj2g3v3224220.1(Lj2g3v3224220.1)
ADU: 107496328
AIP: 107607988
FVE: 101293669
RCN: 112166459
PPER: 18781332
PMUM: 103326559
ZJU: 107434327
CSV: 101220629
CMO: 103490120
MCHA: 111010492
RCU: 8268132
JCU: 105633029
JRE: 108994090
VVI: 100245244
SLY: 101263042
SPEN: 107023955
SOT: 102597725
CANN: 107878763
NSY: 104238187
NTO: 104088408
NAU: 109208192
INI: 109188333
LSV: 111889636
BVG: 104891764
SOE: 110791286
OSA: 4346619
DOSA: Os09t0284200-01(Os09g0284200)
OBR: 102700266
BDI: 100830667
ATS: 109746857(LOC109746857)
SBI: 8062062
ZMA: 100384804
SITA: 101775055
DCT: 110092619
PEQ: 110032677
ATR: 18429752
APRO: F751_6788
SCE: YDR075W(PPH3)
ERC: Ecym_5547
KMX: KLMA_20019(PPH3)
NCS: NCAS_0A03850(NCAS0A03850)
NDI: NDAI_0C05940(NDAI0C05940)
TPF: TPHA_0A02100(TPHA0A02100)
TBL: TBLA_0A08610(TBLA0A08610)
TDL: TDEL_0B04110(TDEL0B04110)
KAF: KAFR_0B02350(KAFR0B02350)
PIC: PICST_50823(MCO15)
CAL: CAALFM_CR03800CA(PPH3)
SLB: AWJ20_2010(PPH3)
CNE: CNA03970
CNB: CNBA3770
PPL: POSPLDRAFT_118560(PP2A-1)
ABP: AGABI1DRAFT56885(AGABI1DRAFT_56885)
ABV: AGABI2DRAFT229218(AGABI2DRAFT_229218)
MGL: MGL_2441
MRT: MRET_3320
ECU: ECU09_0980(pp1-1) ECU10_1280
DDI: DDB_G0272116(ppp4C)
DFA: DFA_06386(ppp4C)
EHI: EHI_010290(43.t00014) EHI_031240(63.t00008) EHI_051890(84.t00008) EHI_147720(142.t00019) EHI_151480(2.t00060) EHI_178880(15.t00037)
PYO: PY17X_0831800(PY00448)
PCB: PCHAS_082880(PC000103.04.0)
TAN: TA12805
TPV: TP02_0042
BBO: BBOV_III010990(17.m07947)
CPV: cgd1_2360
SMIN: v1.2.027889.t1(symbB.v1.2.027889.t1)
SPAR: SPRG_07040
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R
  Title
A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.
  Journal
Mol Cell Proteomics 4:1725-40 (2005)
DOI:10.1074/mcp.M500231-MCP200
  Sequence
[hsa:5531]
Reference
  Authors
Lee DH, Pan Y, Kanner S, Sung P, Borowiec JA, Chowdhury D
  Title
A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination.
  Journal
Nat Struct Mol Biol 17:365-72 (2010)
DOI:10.1038/nsmb.1769
  Sequence
[hsa:5531]

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