KEGG ORTHOLOGY: K19414

ORTHOLOGY: K19414

Entry

K19414                      KO

Symbol

PHF2, JHDM1E

Name

lysine-specific demethylase PHF2 [EC:1.14.11.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K19414  PHF2, JHDM1E; lysine-specific demethylase PHF2
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   Histone demethylases
    K19414  PHF2, JHDM1E; lysine-specific demethylase PHF2

Genes

HSA:	5253(PHF2)

PTR:	100609290(PHF2)

PPS:	100985155(PHF2)

GGO:	101124258(PHF2)

PON:	100452983(PHF2)

NLE:	100595704(PHF2)

HMH:	116475428(PHF2)

MCC:	717585(PHF2)

MCF:	102134246(PHF2)

MTHB:

126937820

MNI:	105498876(PHF2)

CSAB:

103219775(PHF2)

CATY:

105579027(PHF2)

PANU:

101010328(PHF2)

TGE:	112608388(PHF2)

MLEU:

105553388(PHF2)

RRO:	104671600(PHF2)

RBB:	108512023(PHF2)

TFN:	117098317(PHF2)

PTEH:

111523301(PHF2)

CANG:

105501493(PHF2)

CJC:	100401051(PHF2)

SBQ:	101033736(PHF2)

CIMI:

108316777(PHF2)

CSYR:

103261147(PHF2)

MMUR:

105856657(PHF2)

LCAT:

123645753(PHF2)

PCOQ:

105826468(PHF2)

OGA:	100947363(PHF2)

MMU:	18676(Phf2)

MCAL:

110307927(Phf2)

MPAH:

110333692(Phf2)

RNO:	306814(Phf2)

MCOC:

116082785(Phf2)

ANU:	117713656(Phf2)

MUN:	110549218(Phf2)

CGE:	100764126(Phf2)

MAUA:

101837656(Phf2)

PROB:

127229264(Phf2)

PLEU:

114692055(Phf2)

MORG:

121434033 121443247

MFOT:

126502856

AAMP:

119816724(Phf2)

NGI:	103749789(Phf2)

HGL:	101698987(Phf2)

CPOC:

100722251(Phf2)

CCAN:

109701140(Phf2)

DORD:

105993231(Phf2)

DSP:	122113667(Phf2)

PLOP:

125348314(Phf2)

NCAR:

124965525

MMMA:

107159678(Phf2)

OCU:

100354246

OPI:	101517870(PHF2)

TUP:	102467846(PHF2)

GVR:	103602949(PHF2)

CFA:	484208(PHF2)

CLUD:

112644892(PHF2)

VVP:	112908874(PHF2)

VLG:	121484227(PHF2)

NPO:	129499739(PHF2)

AML:	100476342(PHF2)

UMR:	103663175(PHF2)

UAH:	113270109(PHF2)

UAR:	123776414(PHF2)

ELK:

111153547

LLV:

125083817

MPUF:

101681867(PHF2)

MNP:	132024174(PHF2)

MLK:	131812040(PHF2)

NVS:	122917783(PHF2)

ORO:	101384852(PHF2)

EJU:	114200761(PHF2)

ZCA:	113934479(PHF2)

MLX:	118026235(PHF2)

NSU:	110582862 110584350(PHF2)

LWW:

102735760

FCA:	101092898(PHF2)

PYU:	121013583(PHF2)

PCOO:

112868528(PHF2)

PBG:	122475394(PHF2)

PVIV:

125150185(PHF2)

LRUF:

124527566

PTG:	102952787(PHF2)

PPAD:

109257897(PHF2)

PUC:

125924198

AJU:

106985722

HHV:	120223363(PHF2)

BTA:	537728(PHF2)

BOM:	102283132(PHF2)

BIU:	109563268(PHF2)

BBUB:

102406502(PHF2)

BBIS:

104985689(PHF2)

CHX:	102191332(PHF2)

OAS:	101111079(PHF2)

BTAX:

128052209(PHF2)

ODA:	120867302(PHF2)

CCAD:

122431731(PHF2)

SSC:	100514572(PHF2)

CFR:	102510814(PHF2)

CBAI:

105078866(PHF2)

CDK:	105084676(PHF2)

VPC:	102534112(PHF2)

BACU:

103009799(PHF2)

BMUS:

118897093(PHF2)

LVE:	103078237(PHF2)

OOR:	101283713(PHF2)

DLE:	111169916(PHF2)

PCAD:

102984444(PHF2)

PSIU:

116755620(PHF2)

NASI:

112397236(PHF2)

ECB:	100058211(PHF2)

EAI:	106846170(PHF2)

MYB:	102244386(PHF2)

MYD:	102767251(PHF2)

MMYO:

118667628(PHF2)

MLF:	102419881(PHF2)

PKL:	118708720(PHF2)

EFUS:

103297879(PHF2)

MNA:	107538159(PHF2)

DRO:	112302828(PHF2)

SHON:

118993723(PHF2)

AJM:	119036777(PHF2)

PDIC:

114512596(PHF2)

PHAS:

123819435(PHF2)

MMF:	118629478(PHF2)

PPAM:

129082365(PHF2)

HAI:	109374071(PHF2)

RFQ:	117032147(PHF2)

PALE:

102887542(PHF2)

PGIG:

120616449(PHF2)

PVP:	105308776(PHF2)

RAY:	107500297(PHF2)

MJV:	108404319(PHF2)

TOD:	119232733(PHF2)

SARA:

101537339(PHF2)

SETR:

126003677(PHF2)

LAV:	100659291(PHF2)

TMU:

101344409

ETF:	101654663(PHF2)

MDO:	100029206(PHF2)

GAS:	123247413(PHF2)

SHR:	100933381(PHF2)

AFZ:

127553273

PCW:	110204980(PHF2)

OAA:	100076575(PHF2)

GGA:	415981(PHF2)

PCOC:

116238738(PHF2)

MGP:	100543263(PHF2)

CJO:	107319693(PHF2)

TPAI:

128078677(PHF2)

LMUT:

125698655(PHF2)

NMEL:

110404697(PHF2)

APLA:

101793339(PHF2)

ACYG:

106040034(PHF2)

CATA:

118253658(PHF2)

AFUL:

116493030(PHF2)

TGU:	100226361(PHF2)

LSR:	110475426(PHF2)

SCAN:

103817105(PHF2)

PMOA:

120499519(PHF2)

OTC:	121333339(PHF2)

PRUF:

121353406(PHF2)

GFR:	102043824(PHF2)

FAB:	101808278(PHF2)

OMA:	130258509(PHF2)

PHI:	102100697(PHF2)

PMAJ:

107210424(PHF2)

CCAE:

111935348(PHF2)

CCW:	104695758(PHF2)

CBRC:

103617721(PHF2)

ETL:	114059862(PHF2)

ZAB:	102061515(PHF2)

ACHL:

103810448(PHF2)

SVG:	106862448(PHF2)

MMEA:

130581950(PHF2)

HRT:	120758141(PHF2)

FPG:	101924040(PHF2)

FCH:	102057341(PHF2)

CLV:	102087428(PHF2)

EGZ:	104134375(PHF2)

NNI:	104022172(PHF2)

PCRI:

104028477(PHF2)

PLET:

104627700(PHF2)

EHS:	104514433(PHF2)

PCAO:

104041004

ACUN:

113484994(PHF2)

TALA:

104365330(PHF2)

PADL:

103924121(PHF2)

AFOR:

103901659(PHF2)

ACHC:

115353707(PHF2)

HALD:

104325624(PHF2)

HLE:	104842213(PHF2)

AGEN:

126049923

GCL:

127021596

CCRI:

104162239(PHF2)

CSTI:

104563465

CMAC:

104486204

MUI:

104547298

BREG:

104636039(PHF2)

FGA:

104077115

GSTE:

104262496

LDI:

104348862

MNB:	103777189(PHF2)

OHA:	104335241(PHF2)

NNT:	104405235(PHF2)

SHAB:

115614808(PHF2)

DPUB:

104300313(PHF2)

PGUU:

104470260

CPEA:

104397810(PHF2)

AVIT:

104276267

CVF:	104290789(PHF2)

RTD:	128915904(PHF2)

CUCA:

104064643(PHF2)

TEO:

104378464

BRHI:

104496917(PHF2)

AAM:	106488709(PHF2)

AROW:

112971491(PHF2)

NPD:	112953122(PHF2)

TGT:	104569798(PHF2)

DNE:	112984751(PHF2)

SCAM:

104152758(PHF2)

ASN:	102372701(PHF2)

AMJ:	106737054(PHF2)

CPOO:

109311339(PHF2)

GGN:	109289124(PHF2)

PSS:	102456294(PHF2)

CMY:	102944431(PHF2)

CCAY:

125639996(PHF2)

DCC:	119858870(PHF2)

CPIC:

101937785(PHF2)

TST:	117879987(PHF2)

CABI:

116836137(PHF2)

MRV:	120368782(PHF2)

ACS:	100554631(phf2)

ASAO:

132769255(PHF2)

PVT:	110084341(PHF2)

SUND:

121922285(PHF2)

PBI:	103059188(PHF2)

PMUR:

107294787(PHF2)

CTIG:

120310298(PHF2)

TSR:	106554875(PHF2)

PGUT:

117677397(PHF2)

APRI:

131190243(PHF2)

PTEX:

113452570(PHF2)

NSS:	113418368(PHF2)

VKO:	123034088(PHF2)

PMUA:

114591669(PHF2)

PRAF:

128408291(PHF2)

ZVI:	118080691(PHF2)

HCG:	128345677(PHF2)

GJA:	107118818(PHF2)

STOW:

125428398(PHF2)

EMC:	129328342(PHF2)

XLA:	108704009(phf2.L) 108704409(phf2.S)

XTR:	100492144(phf2)

NPR:	108795730(PHF2)

RTEM:

120945266(PHF2)

BBUF:

120979875(PHF2)

BGAR:

122943054(PHF2)

MUO:	115472480(PHF2)

GSH:	117351291(PHF2)

DRE:	503778(phf2)

SRX:	107727751 107749503

SANH:

107685641 107691335

SGH:	107556181 107567592

CCAR:

109083130 109095412

CAUA:

113095945 113111108(phf2)

CGIB:

127967732 128022263

PTET:

122353797(phf2)

LROH:

127173515(phf2)

OMC:	131549070(phf2)

PPRM:

120480451(phf2)

RKG:	130085578(phf2)

MAMB:

125256436(phf2)

CIDE:

127522101

MASI:

127426174 127427570

TROS:

130571025(phf2)

TDW:	130410032(phf2)

MANU:

129428045(phf2)

IPU:

108255086

IFU:	128624850(phf2)

PHYP:

113537886(phf2)

SMEO:

124402206(phf2)

TFD:	113641264(phf2)

TVC:	132837777(phf2)

AMEX:

103035869(phf2)

CMAO:

118799281(phf2)

EEE:	113586356(phf2)

CHAR:

105909887(phf2)

TRU:	101073628(phf2)

TFS:	130524968(phf2)

TNG:	GSTEN00012857G001

LCO:	104929681(phf2)

TBEN:

117493492(phf2)

CGOB:

115008596(phf2)

PGEO:

117446561(phf2)

GACU:

117534475(phf2)

EMAC:

134883153(phf2)

ELY:	117257091(phf2)

EFO:	125890675(phf2)

PLEP:

121952824(phf2)

SLUC:

116050239(phf2)

ECRA:

117943174(phf2)

ESP:	116676656 116688688(phf2)

PFLV:

114554035(phf2)

GAT:	120835211(phf2)

PPUG:

119230114(phf2)

AFB:	129105326(phf2)

CLUM:

117730589(phf2)

PSWI:

130208510(phf2)

MSAM:

119886052(phf2)

SCHU:

122884991(phf2)

CUD:	121506880(phf2)

ALAT:

119020928(phf2)

MZE:	101483308(phf2)

ONL:	100705594(phf2)

OAU:	116313734(phf2)

OLA:	101157612(phf2)

OML:	112145091(phf2)

CSAI:

133449071(phf2)

XMA:	102232313(phf2)

XCO:	114135481(phf2)

XHE:

116710720

PRET:

103465488(phf2)

PFOR:

103152735(phf2)

PLAI:

106938585(phf2)

PMEI:

106906699(phf2)

GAF:	122834111(phf2)

PPRL:

129354796(phf2)

CVG:	107103635(phf2)

CTUL:

119786074(phf2)

GMU:	124856706(phf2)

NFU:	107373657(phf2)

KMR:	108250417(phf2)

ALIM:

106526954(phf2)

NWH:	119411636(phf2)

AOCE:

111588452(phf2)

MCEP:

125006402(phf2)

CSEM:

103386476(phf2)

POV:	109629366(phf2)

SSEN:

122784483

HHIP:

117760916(phf2)

HSP:	118104694(phf2)

SMAU:

118309480(phf2)

LCF:

108886560

SDU:	111221657(phf2)

SLAL:

111668652(phf2)

XGL:	120783210(phf2)

HCQ:	109514826(phf2)

SSCV:

125977035

SBIA:

133506965(phf2)

PEE:	133409301(phf2)

PTAO:

133483900(phf2)

BPEC:

110171124(phf2)

MALB:

109970608(phf2)

BSPL:

114855122(phf2)

SJO:	128355739(phf2)

SASA:

106591232(phf2)

STRU:

115149923 115207235

OTW:

112237494

OMY:	110494860(phf2) 110529064

OGO:	124003564 124024191(phf2)

ONE:

115124499

OKI:	109884347 109884472

OKE:	118377153 118380784(phf2)

SNH:

120043569

CCLU:

121575388 121578749(phf2)

ELS:	105009148(phf2)

SFM:	108923453(phf2) 108925545

PKI:	111840339 111857011(phf2)

AANG:

118210997(phf2)

LOC:	102694544(phf2)

PSPA:

121298147(phf2) 121328734

ARUT:

117412249 117413713

PSEX:

120540313(phf2)

LCM:	102361079(PHF2)

CMK:	103185036(phf2)

RTP:	109923230(phf2)

CPLA:

122558989(phf2)

HOC:	132822326(phf2)

LERI:

129704810(phf2)

VJA:

111272994

» show all

Reference

PMID:21532585

Authors

Baba A, Ohtake F, Okuno Y, Yokota K, Okada M, Imai Y, Ni M, Meyer CA, Igarashi K, Kanno J, Brown M, Kato S

Title

PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B.

Journal

Nat Cell Biol 13:668-75 (2011)
DOI:10.1038/ncb2228

Sequence

[hsa:5253]

Reference

PMID:20129925

Authors

Wen H, Li J, Song T, Lu M, Kan PY, Lee MG, Sha B, Shi X

Title

Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.

Journal

J Biol Chem 285:9322-6 (2010)
DOI:10.1074/jbc.C109.097667

Sequence

[hsa:5253]

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