KEGG   ORTHOLOGY: K20872Help
Entry
K20872                      KO                                     

Name
NEK2
Definition
NIMA (never in mitosis gene a)-related kinase 2 [EC:2.7.11.1]
Disease
H00527  Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2
   01009 Protein phosphatases and associated proteins
    K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  NEK family
   K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2
BRITE hierarchy
Genes
HSA: 4751(NEK2)
PTR: 457714(NEK2)
PPS: 100977113(NEK2)
GGO: 101131756(NEK2)
PON: 100451891(NEK2)
NLE: 100603230(NEK2)
MCC: 711473(NEK2)
MCF: 101865338(NEK2)
CSAB: 103230133(NEK2)
RRO: 104669502(NEK2)
RBB: 108515871(NEK2)
CJC: 100413885(NEK2)
SBQ: 101030856(NEK2)
MMU: 18005(Nek2)
MCAL: 110301800(Nek2)
MPAH: 110321947(Nek2)
RNO: 114482(Nek2) 690209(Nek2l1)
CGE: 100751300(Nek2)
NGI: 103727043(Nek2)
HGL: 101707017(Nek2)
CCAN: 109692298(Nek2)
OCU: 100339755(NEK2)
TUP: 102490860(NEK2)
CFA: 480021(NEK2)
VVP: 112907148(NEK2)
AML: 100476385(NEK2)
UMR: 103672528(NEK2)
UAH: 113262667(NEK2)
ORO: 101374396(NEK2)
ELK: 111150772
FCA: 101085774(NEK2)
PTG: 102948798(NEK2)
PPAD: 109254824(NEK2)
AJU: 106966774(NEK2)
BTA: 523998(NEK2)
BOM: 102265765(NEK2)
BBUB: 102414632(NEK2)
CHX: 102187516(NEK2)
OAS: 101118973(NEK2)
SSC: 397258(NEK2)
CFR: 102508116(NEK2)
CDK: 105099315(NEK2)
BACU: 103011650(NEK2)
LVE: 103074028(NEK2)
OOR: 101279402(NEK2)
DLE: 111184611(NEK2)
PCAD: 102986416(NEK2)
ECB: 100054759(NEK2)
EPZ: 103551966(NEK2)
EAI: 106827190(NEK2)
MYB: 102242948(NEK2)
MYD: 102765428(NEK2)
MNA: 107538855(NEK2)
HAI: 109379115(NEK2)
DRO: 112296574(NEK2)
PALE: 102880231(NEK2)
RAY: 107521654(NEK2)
MJV: 108389728
LAV: 100659014(NEK2)
TMU: 101355559
MDO: 100016325(NEK2)
SHR: 100927602(NEK2)
PCW: 110222723(NEK2)
OAA: 100078509(NEK2)
GGA: 421376(NEK2)
MGP: 100540058(NEK2)
CJO: 107311098(NEK2)
NMEL: 110395525(NEK2)
APLA: 101789958(NEK2)
ACYG: 106031528(NEK2)
TGU: 100224810(NEK2)
LSR: 110479941(NEK2)
SCAN: 103821524(NEK2)
GFR: 102041545(NEK2)
FAB: 101807562(NEK2)
PHI: 102103915(NEK2)
PMAJ: 107202558(NEK2)
CCAE: 111926174(NEK2)
CCW: 104685648(NEK2)
ETL: 114070503(NEK2)
FPG: 101921856(NEK2)
FCH: 102053646(NEK2)
CLV: 102088160(NEK2)
EGZ: 104128735(NEK2)
NNI: 104019674(NEK2)
ACUN: 113477942(NEK2)
PADL: 103922099(NEK2)
AAM: 106490475(NEK2)
ASN: 102386195(NEK2)
AMJ: 102562384(NEK2)
PSS: 102445425(NEK2)
CMY: 102944510(NEK2)
CPIC: 101932375(NEK2)
ACS: 100565749(nek2)
PVT: 110079512(NEK2)
PBI: 103063175(NEK2)
PMUR: 107288584(NEK2)
TSR: 106542688(NEK2)
PMUA: 114594698(NEK2)
GJA: 107124217(NEK2)
XLA: 379177(nek2.S)
XTR: 100328980(nek2)
NPR: 108785497(NEK2)
DRE: 394025(nek2)
SRX: 107712406 107751289(nek2)
SANH: 107685765(nek2) 107695968
CCAR: 109049986 109113828(nek2)
IPU: 108257856(nek2)
PHYP: 113531832(nek2)
AMEX: 103024375(nek2)
EEE: 113572246(nek2)
TRU: 101064124(nek2)
LCO: 104932458(nek2)
NCC: 104961449(nek2)
MZE: 101484939
ONL: 100698486(nek2)
OLA: 101168418(nek2)
XMA: 102221383(nek2)
XCO: 114158752(nek2)
PRET: 103457420(nek2)
CVG: 107093138(nek2)
NFU: 107377682(nek2)
KMR: 108233396(nek2)
ALIM: 106533495(nek2)
AOCE: 111587158(nek2)
CSEM: 103380898(nek2)
POV: 109647609(nek2)
LCF: 108895981(nek2)
SDU: 111238181(nek2)
SLAL: 111661393(nek2)
HCQ: 109508002(nek2) 109528459
BPEC: 110173925(nek2)
MALB: 109962269(nek2)
SASA: 106571199
SALP: 111954623
ELS: 105015339(nek2)
SFM: 108929266(nek2)
PKI: 111858041(nek2)
LCM: 102365936(NEK2)
CMK: 103186151(nek2)
RTP: 109912192(nek2)
CIN: 100176299
APLC: 110981931
SKO: 100376653
DME: Dmel_CG17256(Nek2)
DER: 6551507
DSI: Dsimw501_GD29551(Dsim_GD29551)
DSR: 110184539
DPE: 6597614
DMN: 108155940
DWI: 6649156
DAZ: 108619866
DNV: 108656781
DHE: 111598826
MDE: 101900193
LCQ: 111687301
CLEC: 106665699
ZNE: 110840024
PVM: 113803762
PCAN: 112570994
CRG: 105319616
MYI: 110460306
LAK: 106166713
EPA: 110254698
ADF: 107352834
AMIL: 114953003
PDAM: 113669837
SPIS: 111328164
DGT: 114525729
HMG: 100205637
AQU: 100634526
SCE: YAR018C(KIN3)
ERC: Ecym_5252
KMX: KLMA_10188(KIN3)
NCS: NCAS_0E01560(NCAS0E01560)
NDI: NDAI_0G01760(NDAI0G01760)
TPF: TPHA_0H00750(TPHA0H00750)
TBL: TBLA_0G00820(TBLA0G00820)
TDL: TDEL_0D04450(TDEL0D04450)
KAF: KAFR_0C00920(KAFR0C00920)
PIC: PICST_79384(KIN3)
CAL: CAALFM_C210530CA(KIN3)
SLB: AWJ20_3864(KIN3)
NCR: NCU03187(nim-1)
NTE: NEUTE1DRAFT126102(NEUTE1DRAFT_126102)
MGR: MGG_03026
SSCK: SPSK_03048
MAW: MAC_06657
MAJ: MAA_08441
CMT: CCM_04855
MBE: MBM_07412
ANI: AN9504.2
ANG: ANI_1_986104(An12g08100)
ABE: ARB_01800
TVE: TRV_04735
PTE: PTT_12804
SPO: SPAC19E9.02(fin1)
CNE: CNI02840
CNB: CNBH2710
ABP: AGABI1DRAFT105305(AGABI1DRAFT_105305)
ABV: AGABI2DRAFT118840(AGABI2DRAFT_118840)
MGL: MGL_1688
MRT: MRET_0788
DDI: DDB_G0270814(nek2)
DFA: DFA_00459(nek2)
TAN: TA11560
TPV: TP02_0139
BBO: BBOV_III010080(17.m07876)
CPV: cgd1_1490
SPAR: SPRG_00339
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7522034
  Authors
Schultz SJ, Fry AM, Sutterlin C, Ried T, Nigg EA
  Title
Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans.
  Journal
Cell Growth Differ 5:625-35 (1994)
  Sequence
[hsa:4751]

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