KEGG   ORTHOLOGY: K23588
Entry
K23588                      KO                                     

Name
MLLT6_10, AF17_10
Definition
protein AF-17/10
Disease
H00002  T-cell acute lymphoblastic leukemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K23588  MLLT6_10, AF17_10; protein AF-17/10
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    Dot1-containing complex
     K23588  MLLT6_10, AF17_10; protein AF-17/10
Genes
HSA: 4302(MLLT6) 8028(MLLT10)
PTR: 450343(MLLT10) 454612(MLLT6)
PPS: 100974167(MLLT6) 100981109(MLLT10)
GGO: 101125850(MLLT10) 101153932(MLLT6)
PON: 100431971(MLLT6) 100457847(MLLT10)
NLE: 100587215(MLLT10) 100597060(MLLT6)
MCC: 694045(MLLT6) 709083
MCF: 101866062 102121060(MLLT6)
CSAB: 103237988 103243566(MLLT6)
RRO: 104665682(MLLT10) 104674892(MLLT6)
RBB: 108527769(MLLT10) 108533950(MLLT6)
CJC: 100401494(MLLT6) 100415119(MLLT10)
SBQ: 101041978(MLLT6) 101050982(MLLT10)
MMU: 17354(Mllt10) 246198(Mllt6)
MCAL: 110290318(Mllt10) 110305005(Mllt6)
MPAH: 110319702(Mllt10) 110331646(Mllt6)
RNO: 303504(Mllt6) 361285(Mllt10)
MUN: 110545146(Mllt10) 110554266(Mllt6)
CGE: 100754095(Mllt10) 100764936(Mllt6)
NGI: 103733015(Mllt10) 103743798(Mllt6)
HGL: 101706801(Mllt10) 101723061(Mllt6)
CCAN: 109687624(Mllt10) 109698569(Mllt6)
OCU: 100342728(MLLT10) 100354131(MLLT6)
TUP: 102470464(MLLT6) 102480180(MLLT10)
CFA: 487096(MLLT10) 608565(MLLT6)
VVP: 112917804(MLLT6) 112931153(MLLT10)
AML: 100463881(MLLT10) 100478567(MLLT6)
UMR: 103662119(MLLT6) 103664251
UAH: 113241345(MLLT10) 113265539(MLLT6)
ORO: 101364541(MLLT10) 101373410(MLLT6)
FCA: 101095180(MLLT10) 101099601(MLLT6)
PTG: 102959686(MLLT6) 102967024(MLLT10)
PPAD: 109247392(MLLT6) 109273656(MLLT10)
AJU: 106980471(MLLT6) 106984549(MLLT10)
BTA: 519864(MLLT10) 538601(MLLT6)
BOM: 102284793(MLLT6) 102288391(MLLT10)
BIU: 109573284(MLLT6)
BBUB: 102389078(MLLT6) 102392087(MLLT10)
CHX: 102174064(MLLT6) 102190530(MLLT10)
OAS: 101102576(MLLT6) 101113089(MLLT10)
SSC: 100521678(MLLT10) 102158177(MLLT6)
CFR: 102515129(MLLT6) 102521951(MLLT10)
CDK: 105084917(MLLT10) 105106965(MLLT6)
BACU: 103014524(MLLT10) 103020038(MLLT6)
LVE: 103072838(MLLT10) 103090786(MLLT6)
OOR: 101269584(MLLT10) 101276140(MLLT6)
DLE: 111166230(MLLT6) 111178047(MLLT10)
PCAD: 102988452(MLLT10) 102990867(MLLT6)
ECB: 100067409(MLLT10) 100147431(MLLT6)
EPZ: 103543773(MLLT10) 103552966(MLLT6)
EAI: 106826257(MLLT6) 106846314(MLLT10)
MYB: 102251477(MLLT6) 102259495(MLLT10)
MYD: 102763929(MLLT6) 102770165(MLLT10)
MNA: 107528951(MLLT6) 107546335(MLLT10)
HAI: 109380774(MLLT6) 109394753(MLLT10)
DRO: 112316472(MLLT6) 112318956(MLLT10)
PALE: 102892481(MLLT6) 102898402(MLLT10)
RAY: 107499838(MLLT10) 107520693(MLLT6)
MJV: 108387287(MLLT6)
LAV: 100654520 100670138(MLLT10)
MDO: 100018649(MLLT6) 100019888(MLLT10)
SHR: 100929253(MLLT10) 100930881(MLLT6)
PCW: 110194509(MLLT10) 110215709(MLLT6)
OAA: 100079185(MLLT10) 103167343(MLLT6)
GGA: 419995(MLLT6) 420509(MLLT10)
MGP: 100544183(MLLT10) 104914602
CJO: 107308973(MLLT10) 107325154(MLLT6)
NMEL: 110388650(MLLT6) 110394192(MLLT10)
APLA: 101795242(MLLT10) 101795350(MLLT6)
ACYG: 106030326(MLLT10) 106048474(MLLT6)
TGU: 100225779(MLLT10) 100232014(MLLT6)
LSR: 110470609(MLLT10) 110479491(MLLT6)
SCAN: 103812777(MLLT10) 103821687(MLLT6)
GFR: 102031810(MLLT6) 102034270(MLLT10)
FAB: 101813212(MLLT10) 107604425
PHI: 102104866(MLLT10) 102106708(MLLT6)
PMAJ: 107198235(MLLT10) 107199019(MLLT6)
CCAE: 111924148(MLLT10) 111940016(MLLT6)
CCW: 104689357(MLLT10)
ETL: 114059314(MLLT10) 114070668(MLLT6)
FPG: 101916859(MLLT10) 101923406(MLLT6)
FCH: 102045752(MLLT6) 102052976(MLLT10)
CLV: 102088458(MLLT10) 102090225(MLLT6)
EGZ: 104124671(MLLT6) 104125274(MLLT10)
NNI: 104011882(MLLT6) 104016216(MLLT10)
ACUN: 113476403(MLLT10) 113489129(MLLT6)
PADL: 103922420(MLLT10) 103926434(MLLT6)
AAM: 106489302(MLLT6) 106489931
ASN: 102370302(MLLT10) 102372843(MLLT6)
AMJ: 102569360(MLLT10) 102573855(MLLT6)
PSS: 102448641(MLLT10) 102463565(MLLT6)
CMY: 102935808(MLLT10) 102944216(MLLT6)
CPIC: 101935291(MLLT10) 101950038(MLLT6)
ACS: 100556786(mllt6) 100567985(mllt10)
PVT: 110074868(MLLT6) 110083351(MLLT10)
PBI: 103048186 103048835(MLLT6)
PMUR: 107282643(MLLT6) 107283631(MLLT10)
TSR: 106540852(MLLT10) 106541164
PMUA: 114582704(MLLT6) 114607039(MLLT10)
GJA: 107109393(MLLT10) 107111477(MLLT6)
XLA: 108700792(mllt6.L) 108702513(mllt6.S) 108719864 494767(mllt10.L)
XTR: 100036598(mllt10) 549549(mllt6)
NPR: 108790733(MLLT6) 108793419(MLLT10)
DRE: 492342(mllt10)
SRX: 107727223(mllt10) 107741929
CCAR: 109050134
IPU: 108256345(mllt10)
PHYP: 113541140(mllt10)
AMEX: 103024061(mllt10)
EEE: 113589052(mllt10)
TRU: 101067928(mllt10) 101080216(mllt6)
LCO: 104920381(mllt6) 104922360(mllt10)
NCC: 104945776(mllt10) 104956494(mllt6)
MZE: 101485764(mllt6) 101487338(mllt10)
ONL: 100690404 100710486(mllt10)
OLA: 101165015(mllt10) 101173196(mllt6)
XMA: 102222614(mllt6) 102227525(mllt10)
XCO: 114136658(mllt10) 114144697(mllt6)
PRET: 103463324(mllt6) 103482429(mllt10)
CVG: 107085502(mllt6) 107092253(mllt10)
NFU: 107382972(mllt10) 107393384
KMR: 108243163
ALIM: 106524779 106526919(mllt6)
AOCE: 111569767(mllt10) 111569983
CSEM: 103376962(mllt10) 103384267
POV: 109627653(mllt6) 109629535(mllt10)
LCF: 108884528(mllt6) 108900783(mllt10)
SDU: 111217955(mllt6) 111237270(mllt10)
SLAL: 111660412 111662902(mllt10)
HCQ: 109519158(mllt10) 109521730(mllt6)
BPEC: 110160867(mllt10) 110173820(mllt6)
MALB: 109956812(mllt6) 109965543(mllt10)
ELS: 105021462(mllt6) 105022034(mllt10)
SFM: 108928007(mllt10)
PKI: 111850791(mllt6) 111858964(mllt10)
LCM: 102361815(MLLT10)
CMK: 103176288(mllt10) 103185694(mllt6)
RTP: 109913830(mllt10)
BFO: 118423728
SPU: 590272
APLC: 110973421
DME: Dmel_CG1070(Alh)
DER: 6553057
DSE: 6614197
DSI: Dsimw501_GD19503(Dsim_GD19503) Dsimw501_GD19506(Dsim_GD19506)
DAN: 6500109
DSR: 110191857
DPE: 6594632
DMN: 108155079
DWI: 6647809
DAZ: 108621312
DNV: 108655525
DHE: 111603603
MDE: 101887778
LCQ: 111678413
AAG: 5570881
AME: 726587
BIM: 100747003
BTER: 100644870
CCAL: 108623347
OBB: 114879766
SOC: 105204546
MPHA: 105839309
AEC: 105154481
ACEP: 105621268
PBAR: 105430769
VEM: 105563059
HST: 105191419
DQU: 106750384
CFO: 105258711
LHU: 105679626
PGC: 109857576
OBO: 105275374
PCF: 106791022
MDL: 103572714
TCA: 658502
DPA: 109535771
ATD: 109602332
NVL: 108558337
BMOR: 101742568
PMAC: 106717227
PRAP: 110999667
HAW: 110372441
PXY: 105391497
BTAB: 109039007
CLEC: 106670848
ZNE: 110834888
FCD: 110847180
PVM: 113802868
TUT: 107368513
DPTE: 113793837
CSCU: 111641354
PTEP: 107438219
CBR: CBG06894(Cbr-zfp-1)
PCAN: 112564565
CRG: 105321167
MYI: 110449730
OBI: 106877920
LAK: 106164294
NVE: 5515732
EPA: 110254629
ADF: 107357216
AMIL: 114959777
PDAM: 113672400
SPIS: 111331480
HMG: 100207765
AQU: 100638029
 » show all
Reference
PMID:8058765
  Authors
Prasad R, Leshkowitz D, Gu Y, Alder H, Nakamura T, Saito H, Huebner K, Berger R, Croce CM, Canaani E
  Title
Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia.
  Journal
Proc Natl Acad Sci U S A 91:8107-11 (1994)
DOI:10.1073/pnas.91.17.8107
  Sequence
[hsa:4302]
Reference
PMID:7888665
  Authors
Chaplin T, Ayton P, Bernard OA, Saha V, Della Valle V, Hillion J, Gregorini A, Lillington D, Berger R, Young BD
  Title
A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia.
  Journal
Blood 85:1435-41 (1995)
  Sequence
[hsa:8028]

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