KEGG   PATHWAY: ko00072Help
Entry
ko00072                     Pathway                                

Name
Synthesis and degradation of ketone bodies
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
ko00072  Synthesis and degradation of ketone bodies
ko00072

Ortholog table
Module
M00088  Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone [PATH:ko00072]
Disease
H01076  Alpha-methylacetoacetic aciduria
H01121  Succinyl CoA:3-oxoacid CoA transferase (SCOT) deficiency
H01123  HMG-CoA synthase deficiency
Orthology
K01641  hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
K01640  hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
K01027  3-oxoacid CoA-transferase [EC:2.8.3.5]
K01028  3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
K01029  3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
K00626  acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00019  3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
K01574  acetoacetate decarboxylase [EC:4.1.1.4]
Compound
C00024  Acetyl-CoA
C00164  Acetoacetate
C00207  Acetone
C00332  Acetoacetyl-CoA
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C01089  (R)-3-Hydroxybutanoate
Related
pathway
ko00010  Glycolysis / Gluconeogenesis
ko00071  Fatty acid degradation
ko00620  Pyruvate metabolism
ko00650  Butanoate metabolism

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