KEGG   ORTHOLOGY: K00061
Entry
K00061                      KO                                     

Name
RDH5
Definition
11-cis-retinol dehydrogenase [EC:1.1.1.315]
Pathway
ko00830  Retinol metabolism
Disease
H00825  Familial flecked retina syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K00061  RDH5; 11-cis-retinol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.315  11-cis-retinol dehydrogenase
     K00061  RDH5; 11-cis-retinol dehydrogenase
Other DBs
RN: R03048 R08382
Genes
HSA: 5959(RDH5)
PTR: 467029(RDH5)
PPS: 100988391(RDH5)
GGO: 101125878(RDH5)
PON: 100437933(RDH5)
NLE: 100598708(RDH5)
MCC: 709644(RDH5)
MCF: 107126391(RDH5)
CSAB: 103238482(RDH5)
RRO: 104673711(RDH5)
RBB: 108516026(RDH5)
CJC: 100402026(RDH5)
SBQ: 101051979(RDH5)
MMU: 19682(Rdh5)
MCAL: 110303548(Rdh5)
MPAH: 110327089(Rdh5)
RNO: 366791(Rdh5)
MUN: 110563162(Rdh5)
CGE: 100772460(Rdh5)
NGI: 103738827(Rdh5)
HGL: 101701578(Rdh5)
CCAN: 109696229(Rdh5)
OCU: 100346443(RDH5)
TUP: 102492697(RDH5)
CFA: 481098(RDH5)
VVP: 112922414(RDH5)
AML: 100477613(RDH5)
UMR: 103682388(RDH5)
UAH: 113256460(RDH5)
ORO: 101378842(RDH5)
ELK: 111160231
FCA: 101090450(RDH5)
PTG: 102955802(RDH5)
PPAD: 109270294(RDH5)
AJU: 106986902(RDH5)
BTA: 281448(RDH5)
BOM: 102281461(RDH5)
BIU: 109559397(RDH5)
BBUB: 102405059(RDH5)
CHX: 102179453(RDH5)
OAS: 101115199(RDH5)
SSC: 100517586(RDH5)
CFR: 102522460(RDH5)
CDK: 105086399(RDH5)
BACU: 103013640(RDH5)
LVE: 103070515(RDH5)
OOR: 101272361(RDH5)
DLE: 111173906(RDH5)
PCAD: 102981003(RDH5)
ECB: 100051379(RDH5)
EPZ: 103560206(RDH5)
EAI: 106841311(RDH5)
MYB: 102250054(RDH5)
MYD: 102752637(RDH5)
MNA: 107538219(RDH5)
HAI: 109396898(RDH5)
DRO: 112319078(RDH5)
PALE: 102890960(RDH5)
RAY: 107521261(RDH5)
MJV: 108395935(RDH5)
LAV: 100665758(RDH5)
TMU: 101359207
SHR: 100926680(RDH5)
PCW: 110210897(RDH5)
OAA: 100077776(RDH5)
GGA: 395452(RDH5)
MGP: 100551395
CJO: 107325819(RDH5)
NMEL: 110391116(RDH5)
LSR: 110483543
PHI: 102110114(RDH5)
ETL: 114070099(RDH5)
CLV: 102088293(RDH5)
ASN: 102385802(RDH5)
AMJ: 102572099(RDH5)
PSS: 102452664(RDH5)
CPIC: 101937595(RDH5)
ACS: 100561257(rdh5)
PVT: 110073773(RDH5)
PBI: 103065660(RDH5)
PMUR: 107294926(RDH5)
TSR: 106544310(RDH5)
PMUA: 114587482(RDH5)
GJA: 107121726(RDH5)
XLA: 444623(rdh5.L) 447549(rdh5.S)
XTR: 496830(rdh5)
NPR: 108796498(RDH5)
DRE: 556528(rdh5)
SANH: 107653177
IPU: 108281000(rdh5)
PHYP: 113538008(rdh5)
AMEX: 103042897(rdh5)
EEE: 113580614
TRU: 101069778
LCO: 104922032(rdh5)
NCC: 104964277
MZE: 101481430
ONL: 100710882(rdh5)
OLA: 100125503(rdh5)
XMA: 102227238
XCO: 114135012
PRET: 103464826
CVG: 107103450(rdh5)
NFU: 107385384(rdh5)
KMR: 108231532(rdh5)
ALIM: 106517650(rdh5)
AOCE: 111576058(rdh5)
CSEM: 103386710(rdh5)
POV: 109635450(rdh5)
LCF: 108902106
SDU: 111233581(rdh5)
SLAL: 111655098(rdh5)
HCQ: 109521663(rdh5)
BPEC: 110173750(rdh5)
MALB: 109969798(rdh5)
SALP: 111970500
ELS: 105007069
LCM: 102365116
CMK: 103180707(rdh5)
PDAM: 113684761
SPIS: 111327939
 » show all
Reference
PMID:7836368
  Authors
Simon A, Hellman U, Wernstedt C, Eriksson U
  Title
The retinal pigment epithelial-specific 11-cis retinol dehydrogenase belongs to the family of short chain alcohol dehydrogenases.
  Journal
J Biol Chem 270:1107-12 (1995)
DOI:10.1074/jbc.270.3.1107
  Sequence
[bta:281448]
Reference
  Authors
Liden M, Romert A, Tryggvason K, Persson B, Eriksson U
  Title
Biochemical defects in 11-cis-retinol dehydrogenase mutants associated with fundus albipunctatus.
  Journal
J Biol Chem 276:49251-7 (2001)
DOI:10.1074/jbc.M107337200
  Sequence
[hsa:5959]

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