| Entry |
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| Symbol |
GLUD1_2, gdhA
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| Name |
glutamate dehydrogenase (NAD(P)+) [EC: 1.4.1.3]
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| Pathway |
| map00250 | Alanine, aspartate and glutamate metabolism |
| map01120 | Microbial metabolism in diverse environments |
| map04964 | Proximal tubule bicarbonate reclamation |
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| Module |
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| Reaction |
| R00243 | L-glutamate:NAD+ oxidoreductase (deaminating) |
| R00248 | L-glutamate:NADP+ oxidoreductase (deaminating) |
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| Disease |
| H01267 | Familial hyperinsulinemic hypoglycemia |
| H01400 | Secondary hyperammonemia |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09102 Energy metabolism
00910 Nitrogen metabolism
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
00220 Arginine biosynthesis
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
09150 Organismal Systems
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
Enzymes [BR:ko01000]
1. Oxidoreductases
1.4 Acting on the CH-NH2 group of donors
1.4.1 With NAD+ or NADP+ as acceptor
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
Exosome [BR:ko04147]
Exosomal proteins
Exosomal proteins of breast cancer cells
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+)
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Frigerio F, Casimir M, Carobbio S, Maechler P |
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| Title |
Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis. |
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| Journal |
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| Reference |
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| Authors |
Tapiero H, Mathe G, Couvreur P, Tew KD |
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| Title |
II. Glutamine and glutamate. |
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| Journal |
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| Reference |
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| Authors |
Mavrothalassitis G, Tzimagiorgis G, Mitsialis A, Zannis V, Plaitakis A, Papamatheakis J, Moschonas N |
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| Title |
Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Shashidharan P, Michaelidis TM, Robakis NK, Kresovali A, Papamatheakis J, Plaitakis A |
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| Title |
Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene. |
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| Journal |
J Biol Chem 269:16971-6 (1994) |
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| Sequence |
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