KEGG   ORTHOLOGY: K00399Help
Entry
K00399                      KO                                     

Name
mcrA
Definition
methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00399  mcrA; methyl-coenzyme M reductase alpha subunit
KEGG modules [BR:ko00002]
 Pathway module
  Energy metabolism
   Methane metabolism
    M00567  Methanogenesis, CO2 => methane
     K00399  mcrA; methyl-coenzyme M reductase alpha subunit
    M00357  Methanogenesis, acetate => methane
     K00399  mcrA; methyl-coenzyme M reductase alpha subunit
    M00356  Methanogenesis, methanol => methane
     K00399  mcrA; methyl-coenzyme M reductase alpha subunit
    M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine  => methane
     K00399  mcrA; methyl-coenzyme M reductase alpha subunit
Enzymes [BR:ko01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.4  Transferring alkylthio groups
    2.8.4.1  coenzyme-B sulfoethylthiotransferase
     K00399  mcrA; methyl-coenzyme M reductase alpha subunit
BRITE hierarchy
Other DBs
RN: R04541
GO: 0050524
Genes
MJA: MJ_0083 MJ_0846
MFE: Mefer_0938
MVU: Metvu_0149 Metvu_1194
MFS: MFS40622_0424 MFS40622_1315
MIF: Metin_0281
MJH: JH146_0503 JH146_1056
MIG: Metig_0445 Metig_1237
MMP: MMP1559(mcrA)
MMQ: MmarC5_0017
MMX: MmarC6_1111
MMD: GYY_08645
MAE: Maeo_1268
MVO: Mvol_1128
MMG: MTBMA_c15120(mrtA) MTBMA_c15480(mcrA)
MWO: MWSIV6_1521(mrtA) MWSIV6_1556(mcrA)
MST: Msp_0321(mrtA)
MRU: mru_1924(mcrA)
MEB: Abm4_1526(mcrA)
MMIL: sm9_1353(mrtA) sm9_2027(mcrA)
MEYE: TL18_09320
METH: MBMB1_1682(mcrA) MBMB1_1825(mrtA)
MFC: BRM9_0935(mcrA) BRM9_2156(mrtA)
MFI: DSM1535_0905(mcrA) DSM1535_1095(mrtA)
MCUB: MCBB_1985(mcrA)
MKA: MK0655(mcrA)
MEAR: Mpt1_c02010(mcrA)
MARC: AR505_1396
MAC: MA_4546
MBAR: MSBR2_2279
MBAK: MSBR3_2340
MMA: MM_1240
MMAC: MSMAC_0072
METM: MSMTP_0100
MTHE: MSTHC_1645
MTHR: MSTHT_1644
MHOR: MSHOH_0084
MBU: Mbur_2417(mcrA)
MMET: MCMEM_0559
MMH: Mmah_0612
MPY: Mpsy_0828
MTP: Mthe_0569
MCJ: MCON_0759(mcrA)
MHI: Mhar_0498
MHU: Mhun_2148
MBG: BN140_1521(mcrA1) BN140_1738(mcrA3)
MEMA: MMAB1_1952(mcrA) MMAB1_2235(mcrA)
MBN: Mboo_0582
MPL: Mpal_2309
MPD: MCP_0516(mcrA)
MEZ: Mtc_0908(mcrA)
RCI: RCIX2063(mcrA)
BARC: AOA65_0408(mcrA)
BARB: AOA66_1761(mcrA)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9367957
  Authors
Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK
  Title
Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation.
  Journal
Science 278:1457-62 (1997)
DOI:10.1126/science.278.5342.1457
  Sequence

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