KEGG   ORTHOLOGY: K00414
Entry
K00414                      KO                                     
Symbol
QCR1, UQCRC1
Name
ubiquinol-cytochrome c reductase core subunit 1
Pathway
map00190  Oxidative phosphorylation
map01100  Metabolic pathways
map04260  Cardiac muscle contraction
map04714  Thermogenesis
map04932  Non-alcoholic fatty liver disease
map05010  Alzheimer disease
map05012  Parkinson disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05208  Chemical carcinogenesis - reactive oxygen species
map05415  Diabetic cardiomyopathy
Module
M00152  Cytochrome bc1 complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
   05012 Parkinson disease
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
   05014 Amyotrophic lateral sclerosis
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
   05016 Huntington disease
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
   05020 Prion disease
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
   05022 Pathways of neurodegeneration - multiple diseases
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M16: pitrilysin family
   K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
Other DBs
GO: 0008121
Genes
HSA: 7384(UQCRC1)
PTR: 460348(UQCRC1)
PPS: 100977575
GGO: 101150911
PON: 100452425
NLE: 100593270
MCC: 677864(UQCRC1)
MCF: 102117433
CSAB: 103227597(UQCRC1)
CATY: 105573662
PANU: 101009600
TGE: 112617422
RRO: 104667772
RBB: 108527019
TFN: 117080933
PTEH: 111555381
CJC: 100413740(UQCRC1)
SBQ: 101044497
CSYR: 103270632
MMUR: 105874931
LCAT: 123623309
OGA: 100947724
MMU: 22273(Uqcrc1)
MCAL: 110301545
MPAH: 110327331
RNO: 301011(Uqcrc1)
MCOC: 116073065
MUN: 110565565
CGE: 100766805
MAUA: 101825065
PLEU: 114705194
MORG: 121464397
AAMP: 119810716
NGI: 103750218
HGL: 101719627
CPOC: 100726689
CCAN: 109685725
DORD: 105994609
DSP: 122095608
NCAR: 124993792
OCU: 100347571(UQCRC1)
OPI: 101520891
TUP: 102501709
CFA: 608455(UQCRC1)
CLUD: 112665750
VVP: 112912006
VLG: 121496068
AML: 100478686
UMR: 103674845
UAH: 113256842
UAR: 123779962
ELK: 111143869
LLV: 125080688
MPUF: 101694055
ORO: 101374005
EJU: 114225028
ZCA: 113917309
MLX: 118005048
FCA: 101089499
PYU: 121011166
PBG: 122487236
PTG: 102967145
PPAD: 109247770
AJU: 106979218
HHV: 120229346
BTA: 282393(UQCRC1)
BOM: 102272636
BIU: 109576285
BBUB: 102405660
CHX: 102188264
OAS: 101110095
ODA: 120868239
CCAD: 122424937
SSC: 100156879
CFR: 102514495
CBAI: 105080286
CDK: 105087919
VPC: 102527945
BACU: 103010896
LVE: 103089566
OOR: 101286248
DLE: 111174428
PCAD: 102978880
PSIU: 116762745
ECB: 100053786(UQCRC1)
EPZ: 103556020
EAI: 106830662
MYB: 102238662
MYD: 102762753
MMYO: 118668510
MLF: 102440900
MNA: 107529428
PKL: 118715700
HAI: 109378062
DRO: 112309855
SHON: 118989510
AJM: 119036682
PDIC: 114501536
PHAS: 123830829
MMF: 118633355
RFQ: 117037269
PALE: 102884061
PGIG: 120582316
PVP: 105302414
RAY: 107513320
MJV: 108409257
TOD: 119259667
SARA: 101548951
LAV: 100674803
TMU: 101350351
DNM: 101430732
MDO: 100020379(UQCRC1)
GAS: 123251381
SHR: 100919227
PCW: 110217023
OAA: 100074417
GGA: 416013(UQCRC1)
PCOC: 116238289
MGP: 100549893
CJO: 107319990
NMEL: 110404762
APLA: 101800128
ACYG: 106037917
AFUL: 116493150
TGU: 100225003
LSR: 110471603
SCAN: 103817013
PMOA: 120514085
OTC: 121347295
PRUF: 121351324
GFR: 102039131
FAB: 101818066
PHI: 102112611
PMAJ: 107210449
CCAE: 111935310
CCW: 104683469
CBRC: 103614409
ETL: 114057936
ZAB: 102071295
FPG: 106112817
FCH: 106631153
CLV: 102091216
EGZ: 104126640
PLET: 104619501
PCRI: 104024724
ACUN: 113484827
TALA: 122154041
ACHC: 115333272
HALD: 104323718
CCRI: 104164331
CSTI: 104555018
EHS: 104503613
CMAC: 104478783
FGA: 104070262
GSTE: 104262197
LDI: 104340606
MNB: 103779381
OHA: 104333194
AAM: 106485079
AROW: 112970755
DNE: 112980979
ASN: 102379015
AMJ: 102574306
CPOO: 109311292
GGN: 109289073
PSS: 102452004
CMY: 102946692
CPIC: 101933486
TST: 117880289
CABI: 116837144
MRV: 120369027
ACS: 100558006
PVT: 110081406
SUND: 121923429
PBI: 103055348
PMUR: 107295486
TSR: 106546049
PGUT: 117673836
VKO: 123034139
PMUA: 114591716
ZVI: 118080731
GJA: 107124495
STOW: 125429031
XLA: 379401(uqcrc1.L)
XTR: 549464(uqcrc1)
NPR: 108797963
RTEM: 120945089
BBUF: 120978671
BGAR: 122926473
DRE: 393793(uqcrc1)
CAUA: 113050714
PPRM: 120466944
MAMB: 125265619
IPU: 108272120
PHYP: 113526373
SMEO: 124391524
TFD: 113643191
AMEX: 103038804
EEE: 113569667
TRU: 101077128
LCO: 104933013
NCC: 104952568
CGOB: 115007833
ELY: 117256302
EFO: 125893668
PLEP: 121957102
SLUC: 116035375
ECRA: 117942748
PFLV: 114554016
GAT: 120835449
PPUG: 119229495
MSAM: 119886992
CUD: 121506686
ALAT: 119020708
MZE: 101465335
ONL: 100705312
OAU: 116330175
OLA: 101157209
OML: 112159278
XMA: 102219450
XCO: 114135090
XHE: 116710012
PRET: 103465066
PFOR: 103145776
PLAI: 106953251
PMEI: 106933601
GAF: 122834378
CVG: 107093912
CTUL: 119789684
GMU: 124857541
NFU: 107385415
KMR: 108241165
ALIM: 106518502
NWH: 119412268
AOCE: 111588774
MCEP: 125007144
CSEM: 103386173
POV: 109629394
SSEN: 122768190
HHIP: 117761363
HSP: 118105292
LCF: 108885634
SDU: 111221977
SLAL: 111670978
XGL: 120783421
HCQ: 109522213
BPEC: 110165786
BSPL: 114856240
SASA: 106565806 106582918(QCR1)
ELS: 105017330
LOC: 102682566
LCM: 102354929
RTP: 109924558
AGIF: 122856692
DFR: 124491427
BGT: 106070081
SCE: YBL045C(COR1)
SEUB: DI49_0133
ERC: Ecym_7174
KMX: KLMA_70095(COR1)
NCS: NCAS_0A14910(NCAS0A14910)
NDI: NDAI_0J00570(NDAI0J00570)
TPF: TPHA_0I02880(TPHA0I02880)
TBL: TBLA_0F02710(TBLA0F02710)
TDL: TDEL_0C03470(TDEL0C03470)
KAF: KAFR_0B00620(KAFR0B00620)
KNG: KNAG_0F03620(KNAG0F03620)
PIC: PICST_81500(COR1)
CAL: CAALFM_C505230CA(CaO19.4016)
 » show all
Reference
PMID:8407948
  Authors
Hoffman GG, Lee S, Christiano AM, Chung-Honet LC, Cheng W, Katchman S, Uitto J, Greenspan DS
  Title
Complete coding sequence, intron/exon organization, and chromosomal location of the gene for the core I protein of human ubiquinol-cytochrome c reductase.
  Journal
J Biol Chem 268:21113-9 (1993)
  Sequence
[hsa:7384]

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