KEGG   ORTHOLOGY: K00510Help
Entry
K00510                      KO                                     

Name
HMOX1
Definition
heme oxygenase 1 [EC:1.14.14.18]
Pathway
ko00860  Porphyrin and chlorophyll metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko04066  HIF-1 signaling pathway
ko04216  Ferroptosis
ko04978  Mineral absorption
ko05200  Pathways in cancer
ko05206  MicroRNAs in cancer
ko05225  Hepatocellular carcinoma
ko05418  Fluid shear stress and atherosclerosis
Disease
H01714  Chronic obstructive pulmonary disease (COPD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    K00510  HMOX1; heme oxygenase 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    K00510  HMOX1; heme oxygenase 1
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K00510  HMOX1; heme oxygenase 1
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    K00510  HMOX1; heme oxygenase 1
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    K00510  HMOX1; heme oxygenase 1
   05206 MicroRNAs in cancer
    K00510  HMOX1; heme oxygenase 1
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    K00510  HMOX1; heme oxygenase 1
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K00510  HMOX1; heme oxygenase 1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.18  heme oxygenase (biliverdin-producing)
     K00510  HMOX1; heme oxygenase 1
BRITE hierarchy
Other DBs
RN: R00311
GO: 0004392
Genes
HSA: 3162(HMOX1)
PTR: 470195(HMOX1)
PPS: 100977821(HMOX1)
GGO: 101152785(HMOX1)
PON: 100173339(HMOX1)
NLE: 100587046(HMOX1)
MCC: 719266(HMOX1)
MCF: 101926565(HMOX1)
CSAB: 103223230(HMOX1)
RRO: 104682468(HMOX1)
RBB: 108540867(HMOX1)
CJC: 100405992 100414343(HMOX1)
SBQ: 101039608(HMOX1)
MMU: 15368(Hmox1)
RNO: 24451(Hmox1)
CGE: 100756872(Hmox1)
NGI: 103742105(Hmox1)
HGL: 101708868(Hmox1)
CCAN: 109692950(Hmox1)
OCU: 100008919(HMOX1)
TUP: 102485781(HMOX1)
CFA: 442987(HMOX1)
AML: 100479189(HMOX1)
UMR: 103676557(HMOX1)
ORO: 101364369(HMOX1)
FCA: 101092621(HMOX1)
PTG: 102948800(HMOX1)
AJU: 106981079(HMOX1)
BTA: 513221(HMOX1)
BOM: 102281265(HMOX1)
BIU: 109559493(HMOX1)
PHD: 102333615(HMOX1)
CHX: 100860951(HMOX1)
OAS: 101120910(HMOX1)
SSC: 445512(HMOX1)
CFR: 102505023(HMOX1)
CDK: 105097386(HMOX1)
BACU: 103018426(HMOX1)
LVE: 103077914(HMOX1)
OOR: 101282134(HMOX1)
ECB: 100069058(HMOX1)
EPZ: 103543240(HMOX1)
EAI: 106825719(HMOX1)
MYB: 102248030(HMOX1)
MYD: 102767690(HMOX1)
HAI: 109377639(HMOX1)
RSS: 109445766(HMOX1)
PALE: 102880347(HMOX1)
LAV: 100673521(HMOX1)
TMU: 101351050
MDO: 100024355(HMOX1) 100030714
SHR: 100925365(HMOX1)
OAA: 107547784(HMOX1)
GGA: 396287(HMOX1)
MGP: 100551243(HMOX1)
CJO: 107314345(HMOX1)
APLA: 101805057(HMOX1)
ACYG: 106035937(HMOX1)
TGU: 100226348(HMOX1)
SCAN: 103813211(HMOX1)
GFR: 102043181(HMOX1)
FAB: 101817317(HMOX1)
PHI: 102101610(HMOX1)
PMAJ: 107205203(HMOX1)
CCAE: 111935629(HMOX1)
CCW: 104696269(HMOX1)
FPG: 101915244(HMOX1)
FCH: 102055466(HMOX1)
CLV: 102084894(HMOX1)
EGZ: 104134285(HMOX1)
NNI: 104021567(HMOX1)
ACUN: 113491611(HMOX1)
AAM: 106488415(HMOX1)
ASN: 102373399(HMOX1)
AMJ: 102573866(HMOX1)
PSS: 102462727(HMOX1)
CMY: 102940527(HMOX1)
CPIC: 101950994(HMOX1)
ACS: 100555210(hmox1)
PVT: 110075944(HMOX1)
PBI: 103065892(HMOX1)
PMUR: 107302627(HMOX1)
GJA: 107109423(HMOX1)
XLA: 398965(hmox1.S) 734976(hmox1.L)
XTR: 100488303(hmox1)
NPR: 108793696(HMOX1)
DRE: 402970(hmox1b) 791518(hmox1a)
CCAR: 109057953
AMEX: 103022889 103044464(hmox1)
TRU: 101070079(hmox1)
NCC: 104950512
XMA: 102223107 102233187(hmox1)
NFU: 107376240(hmox1) 107382233
CSEM: 103393699(hmox1)
BPEC: 110172090(hmox1) 110172617
ELS: 105012149(hmox) 105013172(hmox1)
SFM: 108939753
LCM: 102354266(HMOX1)
CMK: 103189669
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
West AR, Oates PS
  Title
Mechanisms of heme iron absorption: current questions and controversies.
  Journal
World J Gastroenterol 14:4101-10 (2008)
DOI:10.3748/wjg.14.4101
Reference
PMID:3345742
  Authors
Yoshida T, Biro P, Cohen T, Muller RM, Shibahara S
  Title
Human heme oxygenase cDNA and induction of its mRNA by hemin.
  Journal
Eur J Biochem 171:457-61 (1988)
DOI:10.1111/j.1432-1033.1988.tb13811.x
  Sequence
[hsa:3162]

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