Entry
Symbol
asm10
Name
N-methyltransferase [EC:2.1.1.-]
Pathway
map01110 Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
K16038 asm10; N-methyltransferase
01051 Biosynthesis of ansamycins
K16038 asm10; N-methyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K16038 asm10; N-methyltransferase
Enzymes [BR:ko01000 ]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.-
K16038 asm10; N-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008 ]
Polyketide tailoring proteins
Methylase
K16038 asm10; N-methyltransferase
BRITE hierarchy
Other DBs
Genes
Taxonomy UniProt
Reference
Authors
Wu Y, Kang Q, Shang G, Spiteller P, Carroll B, Yu TW, Su W, Bai L, Floss HG
Title
N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis.
Journal
Reference
Authors
Spiteller P, Bai L, Shang G, Carroll BJ, Yu TW, Floss HG
Title
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum.
Journal
Reference
Authors
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG
Title
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.
Journal
Sequence