KEGG   ORTHOLOGY: K00718Help
Entry
K00718                      KO                                     

Name
FUT1_2
Definition
galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69]
Pathway
ko00601  Glycosphingolipid biosynthesis - lacto and neolacto series
ko00603  Glycosphingolipid biosynthesis - globo and isoglobo series
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Glycan biosynthesis and metabolism
   00601 Glycosphingolipid biosynthesis - lacto and neolacto series
    K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
   00603 Glycosphingolipid biosynthesis - globo and isoglobo series
    K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.69  type 1 galactoside alpha-(1,2)-fucosyltransferase
     K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
Glycosyltransferases [BR:ko01003]
 Glycan extension
  ABO blood group
   K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
Membrane trafficking [BR:ko04131]
 Endocytosis
  Others
   Fucosyltransferase
    K00718  FUT1_2; galactoside 2-L-fucosyltransferase 1/2
BRITE hierarchy
Other DBs
RN: R05968 R06024 R06027 R06031 R06035 R06041 R06085 R06086 R06089 R06090 R06156 R06170
GO: 0008107
CAZy: GT11
Genes
HSA: 2523(FUT1) 2524(FUT2)
PTR: 104001169 468944(FUT2) 468947(FUT1)
PPS: 100990363(FUT1) 100991035(FUT2) 103785330
GGO: 101131113(FUT1) 101148312(FUT2)
PON: 100171991(FUT1) 100445051(FUT2)
NLE: 100589182 100589750 100592672(FUT1)
MCC: 718252(FUT1) 722582(FUT2)
MCF: 102121228 102121606(FUT2) 102125198(FUT1)
CSAB: 103234986 103234988 103234996(FUT1)
RRO: 104666550(FUT1) 104666555(FUT2) 104666558
RBB: 108523627 108523645(FUT2) 108523649(FUT1)
CJC: 100389529(FUT1) 100896666(FUT2)
MMU: 14343(Fut1) 14344(Fut2) 56546(Sec1)
RNO: 308586(Sec1) 58924(Fut2) 81919(Fut1)
HGL: 101709834(Fut1) 101710190(Fut2)
CCAN: 109682667(Fut2) 109682669(Fut1) 109682676
OCU: 100009290(RFT-II) 100009291(FUT1) 100349124
CFA: 102151792 484396(FUT1) 484398(FUT2)
AML: 100472596 100478397(FUT1) 100478902(FUT2)
ORO: 101374079(FUT1) 101374953(FUT2) 101375248
FCA: 101080847(FUT1) 101085847
PTG: 102962287(FUT2) 102969895(FUT1)
AJU: 106988654 106988710(FUT1)
BTA: 281174(FUT1) 281175(FUT2) 281483(SEC1)
BOM: 102282547(FUT1) 102283305(FUT2) 102283588
BIU: 109572956 109573030(FUT2) 109573041(FUT1)
SSC: 100524201(FUT2A) 397138(FUT1) 397139(FUT2)
CFR: 102521344(FUT1) 102522076(FUT2) 102522586
BACU: 103015344(FUT1)
LVE: 103080875(FUT2) 103081703(FUT1)
OOR: 101289320(FUT1) 101289561(FUT2)
EPZ: 103544534 103553324(FUT1) 103553326(FUT2)
MYB: 102257351(FUT1) 102259445(FUT2)
MYD: 102760565(FUT2) 102767518 102768655(FUT1)
HAI: 109391063(FUT2) 109391098(FUT1)
RSS: 109452483(FUT1) 109452530(FUT2)
PALE: 102885708(FUT1) 102886704(FUT2)
LAV: 100662459 100674697(FUT1) 100675832(FUT2)
OAA: 100085980(FUT1) 100681084(FUT2)
ACS: 100561462(fut2)
PVT: 110078544(FUT2)
PBI: 103053688(FUT2)
GJA: 107122202(FUT2)
XLA: 108696739 108696766(fut1.L) 108697042 108697990(fut2.S) 398668(fut1.S)
LCM: 102356194 102357968(FUT1)
AME: 726095(GB16372)
BIM: 100743109
BTER: 100642421
SOC: 105199316
AEC: 105148166
ACEP: 105624787
PBAR: 105431936
HST: 105188950
CFO: 105255117
LHU: 105672546
PGC: 109852313
NVI: 100116336
TCA: 655912
NVL: 108559505
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2118655
  Authors
Larsen RD, Ernst LK, Nair RP, Lowe JB
  Title
Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen.
  Journal
Proc Natl Acad Sci U S A 87:6674-8 (1990)
DOI:10.1073/pnas.87.17.6674
  Sequence
[hsa:2523]
Reference
PMID:7876235
  Authors
Kelly RJ, Rouquier S, Giorgi D, Lennon GG, Lowe JB
  Title
Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype.
  Journal
J Biol Chem 270:4640-9 (1995)
DOI:10.1074/jbc.270.9.4640
  Sequence
[hsa:2524]

DBGET integrated database retrieval system