KEGG   ORTHOLOGY: K00746
Entry
K00746                      KO                                     
Symbol
CSGALNACT1_2
Name
chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175]
Pathway
map00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
map01100  Metabolic pathways
Module
M00058  Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
Disease
H02551  Skeletal dysplasia with joint laxity and advanced bone age
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.174  glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase
     K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
    2.4.1.175  glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase
     K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
Other DBs
RN: R05929
GO: 0047237 0047238
CAZy: GT7
Genes
HSA: 55454(CSGALNACT2) 55790(CSGALNACT1)
PTR: 450416(CSGALNACT2) 464030(CSGALNACT1)
PPS: 100987599(CSGALNACT1) 100994377(CSGALNACT2)
GGO: 101151962(CSGALNACT2) 101154228(CSGALNACT1)
PON: 100172853(CSGALNACT2) 100442293(CSGALNACT1)
NLE: 100583001(CSGALNACT1) 100602432(CSGALNACT2)
MCC: 703703(CSGALNACT2) 704901(CSGALNACT1)
MCF: 102125913(CSGALNACT1) 102136560(CSGALNACT2)
CSAB: 103215414(CSGALNACT1) 103215756(CSGALNACT2)
CATY: 105571571(CSGALNACT2) 105579259(CSGALNACT1)
PANU: 101012979(CSGALNACT1) 101019767(CSGALNACT2)
TGE: 112630090(CSGALNACT1) 112632117(CSGALNACT2)
RRO: 104653929(CSGALNACT2) 104662459(CSGALNACT1)
RBB: 108513317(CSGALNACT2) 108526479(CSGALNACT1)
TFN: 117082810(CSGALNACT2) 117092780(CSGALNACT1)
PTEH: 111531316(CSGALNACT2) 111545662(CSGALNACT1)
CJC: 100399122(CSGALNACT2) 100407007(CSGALNACT1)
SBQ: 101027448(CSGALNACT2) 101048885(CSGALNACT1)
CSYR: 103268660(CSGALNACT2) 103276583(CSGALNACT1)
MMUR: 105879006(CSGALNACT2) 105882547(CSGALNACT1)
OGA: 100942846(CSGALNACT2) 100948840(CSGALNACT1)
MMU: 234356(Csgalnact1) 78752(Csgalnact2)
MCAL: 110295750(Csgalnact2) 110300279(Csgalnact1)
MPAH: 110315909(Csgalnact2) 110336490(Csgalnact1)
RNO: 297554(Csgalnact2) 306375(Csgalnact1)
MCOC: 116069408(Csgalnact1) 116099473(Csgalnact2)
CGE: 100754969(Csgalnact1) 100770830(Csgalnact2)
PLEU: 114689661(Csgalnact2) 114703120(Csgalnact1)
NGI: 103733802(Csgalnact2) 103747604(Csgalnact1)
HGL: 101700905(Csgalnact1) 101719048(Csgalnact2)
CPOC: 100725703(Csgalnact1) 100735627(Csgalnact2)
CCAN: 109688882(Csgalnact1) 109698852(Csgalnact2)
DORD: 105992963(Csgalnact1) 105998871(Csgalnact2)
DSP: 122122368(Csgalnact2) 122125664(Csgalnact1)
OCU: 100339411(CSGALNACT1) 100339435(CSGALNACT2)
OPI: 101526745(CSGALNACT1) 101533692(CSGALNACT2)
TUP: 102468989(CSGALNACT2) 102490797(CSGALNACT1)
CFA: 482831(CSGALNACT1) 486786(CSGALNACT2)
VVP: 112913575(CSGALNACT2) 112916171(CSGALNACT1)
VLG: 121484927(CSGALNACT2) 121489366(CSGALNACT1)
AML: 100468746(CSGALNACT1) 100484755(CSGALNACT2)
UMR: 103667936(CSGALNACT2) 103677036(CSGALNACT1)
UAH: 113243134(CSGALNACT2) 113245577(CSGALNACT1)
UAR: 123780323(CSGALNACT1) 123800371(CSGALNACT2)
MPUF: 101683049(CSGALNACT2) 101693101(CSGALNACT1)
ORO: 101369554(CSGALNACT2) 101377082(CSGALNACT1)
EJU: 114205257(CSGALNACT2) 114224798(CSGALNACT1)
ZCA: 113919765(CSGALNACT2) 113924441(CSGALNACT1)
MLX: 118009903(CSGALNACT1) 118023420(CSGALNACT2)
FCA: 101096311(CSGALNACT1) 101100841(CSGALNACT2)
PYU: 121036967(CSGALNACT2) 121045298(CSGALNACT1)
PBG: 122472766(CSGALNACT1) 122493001(CSGALNACT2)
PTG: 102956824(CSGALNACT1) 102966347(CSGALNACT2)
PPAD: 109262244(CSGALNACT1) 109264614(CSGALNACT2)
AJU: 106972130(CSGALNACT2) 106978257(CSGALNACT1)
HHV: 120234018(CSGALNACT1) 120249250(CSGALNACT2)
BTA: 509328(CSGALNACT2) 528057(CSGALNACT1)
BOM: 102266543(CSGALNACT1) 102285203(CSGALNACT2)
BIU: 109553356(CSGALNACT1) 109553754(CSGALNACT2)
BBUB: 102402654(CSGALNACT2) 102406891(CSGALNACT1)
CHX: 102179349(CSGALNACT1) 102185714(CSGALNACT2)
OAS: 101118243(CSGALNACT2) 101120469(CSGALNACT1)
SSC: 100157878(CSGALNACT2) 100517735 102166124(CSGALNACT1)
CFR: 102513810(CSGALNACT1) 102514190(CSGALNACT2)
CBAI: 105071120(CSGALNACT1) 105072700(CSGALNACT2)
CDK: 105086444(CSGALNACT1) 105092509(CSGALNACT2)
VPC: 102525594(CSGALNACT1) 102542681(CSGALNACT2)
BACU: 103007226(CSGALNACT2) 103010484(CSGALNACT1)
LVE: 103069443(CSGALNACT2) 103084873(CSGALNACT1)
OOR: 101288535(CSGALNACT2) 101289782(CSGALNACT1)
DLE: 111163996(CSGALNACT2) 111173568(CSGALNACT1)
PCAD: 102982515(CSGALNACT1) 102984892(CSGALNACT2)
PSIU: 116741260(CSGALNACT2) 116746869(CSGALNACT1)
ECB: 100050200(CSGALNACT2) 100052192(CSGALNACT1)
EPZ: 103550620(CSGALNACT2)
EAI: 106824857(CSGALNACT1) 106831340(CSGALNACT2)
MYB: 102244364(CSGALNACT1) 102262652(CSGALNACT2)
MYD: 102764495(CSGALNACT2) 102768920(CSGALNACT1)
MMYO: 118651294(CSGALNACT1) 118670214(CSGALNACT2)
MLF: 102435977(CSGALNACT1) 102443242(CSGALNACT2)
MNA: 107523899(CSGALNACT1) 107532565(CSGALNACT2)
PKL: 118719057(CSGALNACT2) 118730871(CSGALNACT1)
HAI: 109386291(CSGALNACT1) 109395550(CSGALNACT2)
DRO: 112305453(CSGALNACT2) 112321495(CSGALNACT1)
SHON: 118981053(CSGALNACT2) 118984282(CSGALNACT1)
AJM: 119035897(CSGALNACT2) 119060903(CSGALNACT1)
PDIC: 114497160(CSGALNACT2) 114508884(CSGALNACT1)
PHAS: 123807620(CSGALNACT1) 123820932(CSGALNACT2)
MMF: 118622397 118622545 118632143(CSGALNACT2)
RFQ: 117021457(CSGALNACT1) 117036051(CSGALNACT2)
PALE: 102878385(CSGALNACT2) 102889741(CSGALNACT1)
PGIG: 120594629(CSGALNACT2) 120613141(CSGALNACT1)
PVP: 105300712(CSGALNACT1) 105309192(CSGALNACT2)
RAY: 107501339(CSGALNACT1) 107517640(CSGALNACT2)
MJV: 108408000(CSGALNACT2) 108409516
TOD: 119233514(CSGALNACT2) 119257867(CSGALNACT1)
SARA: 101539058 101551713(CSGALNACT1) 101556437(CSGALNACT2)
LAV: 100654033(CSGALNACT1) 100661660(CSGALNACT2)
DNM: 101413578(CSGALNACT2) 101443515(CSGALNACT1)
MDO: 100012272(CSGALNACT2) 100030310(CSGALNACT1)
GAS: 123234841(CSGALNACT1) 123236401(CSGALNACT2)
SHR: 100925396(CSGALNACT1) 100925905(CSGALNACT2)
PCW: 110196399(CSGALNACT1) 110221474(CSGALNACT2)
OAA: 100076249(CSGALNACT2) 100078026(CSGALNACT1)
GGA: 422488(CSGALNACT1) 423632(CSGALNACT2)
PCOC: 116234735(CSGALNACT2) 116238085(CSGALNACT1)
MGP: 100538576(CSGALNACT1) 100550089(CSGALNACT2)
CJO: 107313214(CSGALNACT1) 107315593(CSGALNACT2)
NMEL: 110397662(CSGALNACT1) 110400505(CSGALNACT2)
APLA: 101796158(CSGALNACT2) 101799131(CSGALNACT1)
ACYG: 106032482(CSGALNACT2) 106035122(CSGALNACT1)
AFUL: 116489274(CSGALNACT1) 116491372(CSGALNACT2)
TGU: 100223510(CSGALNACT1) 100231851(CSGALNACT2)
LSR: 110468615(CSGALNACT2) 110471712(CSGALNACT1)
SCAN: 103814021(CSGALNACT2) 103825992(CSGALNACT1)
PMOA: 120502749(CSGALNACT1) 120507270(CSGALNACT2)
OTC: 121336165(CSGALNACT2) 121348464(CSGALNACT1)
PRUF: 121357788(CSGALNACT2) 121360235(CSGALNACT1)
GFR: 102033481(CSGALNACT1) 102043050(CSGALNACT2)
FAB: 101812240(CSGALNACT1) 101820745(CSGALNACT2)
PHI: 102113363(CSGALNACT2) 102113419(CSGALNACT1)
PMAJ: 107203353(CSGALNACT1) 107207041(CSGALNACT2)
CCAE: 111931022(CSGALNACT2) 111944213(CSGALNACT1)
CCW: 104690220(CSGALNACT2) 104697139(CSGALNACT1)
ETL: 114062182(CSGALNACT1) 114062797(CSGALNACT2)
ZAB: 102062833(CSGALNACT1) 102068072(CSGALNACT2)
FPG: 101910473(CSGALNACT1) 101919107(CSGALNACT2)
FCH: 102049509(CSGALNACT2) 102059429(CSGALNACT1)
CLV: 102088612(CSGALNACT1) 102097544(CSGALNACT2)
EGZ: 104129088(CSGALNACT2) 104135540(CSGALNACT1)
NNI: 104015153(CSGALNACT2) 104021307(CSGALNACT1)
ACUN: 113479811(CSGALNACT1) 113483540(CSGALNACT2)
TALA: 104358412(CSGALNACT1) 104358481(CSGALNACT2)
PADL: 103924202(CSGALNACT2) 103925418(CSGALNACT1)
ACHC: 115343740(CSGALNACT1) 115348268(CSGALNACT2)
AAM: 106484360(CSGALNACT1) 106498950(CSGALNACT2)
AROW: 112972176(CSGALNACT1) 112973043(CSGALNACT2)
NPD: 112950503(CSGALNACT2) 112953461(CSGALNACT1)
DNE: 112993256(CSGALNACT1) 112993301(CSGALNACT2)
ASN: 102388579(CSGALNACT2) 102388616(CSGALNACT1)
AMJ: 102562660(CSGALNACT2) 106736723(CSGALNACT1)
CPOO: 109309424(CSGALNACT1) 109324110(CSGALNACT2)
GGN: 109287343(CSGALNACT2) 109301225(CSGALNACT1)
PSS: 102447091(CSGALNACT1) 102458703(CSGALNACT2)
CMY: 102940405(CSGALNACT2) 102945055(CSGALNACT1)
CPIC: 101937753(CSGALNACT2) 101950451(CSGALNACT1)
TST: 117877837(CSGALNACT1) 117880325(CSGALNACT2)
CABI: 116828261(CSGALNACT2) 116834478(CSGALNACT1)
MRV: 120369006(CSGALNACT2) 120406834(CSGALNACT1)
ACS: 100558813(csgalnact2) 100560783(csgalnact1)
PVT: 110083670(CSGALNACT2) 110086324(CSGALNACT1)
SUND: 121927380(CSGALNACT2) 121935771(CSGALNACT1)
PBI: 103048163(CSGALNACT1) 103058428(CSGALNACT2)
PMUR: 107293256(CSGALNACT2) 107302358(CSGALNACT1)
TSR: 106549275(CSGALNACT1) 106551544(CSGALNACT2)
PGUT: 117664777(CSGALNACT1) 117669198(CSGALNACT2)
VKO: 123018334(CSGALNACT2) 123031904(CSGALNACT1)
PMUA: 114581524(CSGALNACT1) 114597096(CSGALNACT2)
ZVI: 118095372(CSGALNACT1) 118096363(CSGALNACT2)
GJA: 107107034(CSGALNACT1) 107115005(CSGALNACT2)
XLA: 108696289(csgalnact2.L) 108706822(csgalnact1.S) 108712229(csgalnact1.L)
XTR: 100124741(csgalnact2) 100497098(csgalnact1)
NPR: 108786604(CSGALNACT2) 108804915(CSGALNACT1)
RTEM: 120909056(CSGALNACT2) 120914590(CSGALNACT1)
BBUF: 120989661(CSGALNACT1) 121004015(CSGALNACT2)
BGAR: 122940592(CSGALNACT2) 122945826(CSGALNACT1)
DRE: 101886904(csgalnact1b) 560826(csgalnact2) 793671(csgalnact1a)
SRX: 107712620 107713273 107726950(csgalnact2) 107743585 107744099(csgalnact1)
PPRM: 120473219(csgalnact2) 120481690(csgalnact1a)
IPU: 108263569(csgalnact2) 108265223(csgalnact1b) 108277248(csgalnact1a)
PHYP: 113533267 113541925(csgalnact2) 113543992
SMEO: 124393878(csgalnact1a) 124399478(csgalnact1b) 124400886(csgalnact2)
TFD: 113636285(csgalnact2) 113656118(csgalnact1b) 113661309(csgalnact1a)
AMEX: 103021869 103029300(csgalnact2) 103045746
EEE: 113585223(csgalnact2) 113590383
TRU: 101071007 101079052(csgalnact2) 101079135
LCO: 104920113(csgalnact1) 104920841 104921883(csgalnact2)
NCC: 104951713 104952731(csgalnact2)
CGOB: 115013493 115017153 115019876(csgalnact2)
ELY: 117248332(csgalnact2) 117251871 117269179 117269204(csgalnact1a)
PLEP: 121944169 121954782(csgalnact2) 121959976(csgalnact1a)
SLUC: 116039395(csgalnact2) 116054357 116062907(csgalnact1a)
ECRA: 117945314 117959414(csgalnact1a) 117960648(csgalnact2)
PFLV: 114556240 114571591(csgalnact1) 114572117(csgalnact2)
GAT: 120820244(csgalnact2) 120830859 120831634(csgalnact1a)
PPUG: 119214041(csgalnact2) 119224975 119226953(csgalnact1a)
MSAM: 119892062 119914529(csgalnact1a) 119917420(csgalnact2)
CUD: 121510272 121511297(csgalnact2) 121525580(csgalnact1a)
MZE: 101469922(csgalnact1) 101474654 101476345(csgalnact2)
ONL: 100702075(csgalnact2) 100706120 100708917
OAU: 116310492(csgalnact1b) 116318798(csgalnact2) 116331736(csgalnact1a)
OLA: 101155793(csgalnact2) 101159591 101162617(csgalnact1)
OML: 112140415 112148788 112161592(csgalnact2) 112163495(csgalnact1a)
XMA: 102221723(csgalnact1) 102233977 102237743(csgalnact2)
XCO: 114137572(csgalnact2) 114149526(csgalnact1) 114154568
XHE: 116713231 116724307(csgalnact1) 116729792
PRET: 103470100 103473476(csgalnact1) 103477114(csgalnact2)
PFOR: 103141822 103142702 103148243(csgalnact2)
PLAI: 106941788 106944945 106951788(csgalnact2)
PMEI: 106912280 106920942(csgalnact2) 106924707
GAF: 122827458 122842267(csgalnact2) 122846841(csgalnact1a)
CVG: 107086272 107088483(csgalnact2) 107088980
CTUL: 119776575(csgalnact1a) 119782922(csgalnact2) 119798533
GMU: 124859018(csgalnact2) 124872656(csgalnact1a) 124877422
NFU: 107373900(csgalnact1) 107375371(csgalnact2) 107394138
KMR: 108231091(csgalnact1a) 108233606 108240679(csgalnact2)
NWH: 119413037 119417530(csgalnact2) 119424842(csgalnact1a)
AOCE: 111564714 111564820(csgalnact1) 111573086(csgalnact2)
CSEM: 103387459(csgalnact2) 103390413(csgalnact1) 103397716
POV: 109626572 109632851(csgalnact2) 109637154
SSEN: 122758252(csgalnact1a) 122769482 122781771(csgalnact2)
HHIP: 117768538 117772080(csgalnact1a) 117775771(csgalnact2)
LCF: 108874113 108882236 108886250(csgalnact2)
SDU: 111220601(csgalnact2) 111230915 111239886(csgalnact1)
SLAL: 111645131 111656793(csgalnact1) 111669464
XGL: 120796223(csgalnact2) 120805287 120806778(csgalnact1a)
HCQ: 109523133(csgalnact2) 109525674 109527907
BPEC: 110157439 110162232(csgalnact2) 110167048
MALB: 109956612 109960538(csgalnact2) 109972367
ELS: 105014092 105026679(csgalnact1) 105028646(csgalnact2)
SFM: 108924956(csgalnact1) 108932703(csgalnact2)
PKI: 111849050(csgalnact2) 111849915(csgalnact1)
AANG: 118206747(csgalnact1b) 118212966(csgalnact1a) 118218071(csgalnact2)
LOC: 102686672(csgalnact2) 102694271(csgalnact1)
PSPA: 121304057(csgalnact1a) 121314225 121325711(csgalnact2)
ARUT: 117408808 117418452(csgalnact2) 117420659(csgalnact1a)
LCM: 102358556(CSGALNACT2) 102366614(CSGALNACT1)
CMK: 103181211(csgalnact2) 103186731
RTP: 109912510(csgalnact2) 109917511(csgalnact1)
BFO: 118410920
BBEL: 109485484
CIN: 100177589
SPU: 579124
APLC: 110991016
SKO: 100368195
DME: Dmel_CG12913(CG12913)
DER: 6543177
DSE: 6608480
DSI: Dsimw501_GD10724(Dsim_GD10724)
DAN: 6495632
DSR: 110178256
DPE: 6590525
DMN: 108159923
DWI: 6646033
DGR: 6560215
DAZ: 108615801
DNV: 108653728
DVI: 6625749
ACOZ: 120953354
AARA: 120893196
AAG: 5578232
CPII: 120425696
CNS: 116345176
NVI: 100121958
CSOL: 105364133
TPRE: 106650500
MDL: 103578840
CGLO: 123262930
FAS: 105268100
DAM: 107041616
AGIF: 122854813
CCIN: 107270238
TCA: 659298
DPA: 109542837
SOY: 115886992
ATD: 109600607
CSET: 123314829
AGB: 108911720
LDC: 111503128
NVL: 108559669
PPYR: 116163942
OTU: 111420233
BTAB: 109034694
CLEC: 112126951
HHAL: 106691779
NLU: 111056642
ZNE: 110838755
DMK: 116932720
PCAN: 112575074
BGT: 106055870
GAE: 121380061
HRF: 124142722
HRJ: 124275673
CRG: 105325571
MYI: 110456749
PMAX: 117330640
MMER: 123563253
OSN: 115225312
LAK: 106167613
DGT: 114517412
AQU: 105313529
 » show all
Reference
  Authors
Uyama T, Kitagawa H, Tamura Ji J, Sugahara K
  Title
Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate.
  Journal
J Biol Chem 277:8841-6 (2002)
DOI:10.1074/jbc.M111434200
  Sequence
[hsa:55790]

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