KEGG   ORTHOLOGY: K00802Help
Entry
K00802                      KO                                     

Name
SMS
Definition
spermine synthase [EC:2.5.1.22]
Pathway
ko00270  Cysteine and methionine metabolism
ko00330  Arginine and proline metabolism
ko00480  Glutathione metabolism
ko01100  Metabolic pathways
Disease
H00597  Snyder-Robinson syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K00802  SMS; spermine synthase
   00330 Arginine and proline metabolism
    K00802  SMS; spermine synthase
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K00802  SMS; spermine synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.22  spermine synthase
     K00802  SMS; spermine synthase
BRITE hierarchy
Other DBs
RN: R02869
COG: COG0421
GO: 0016768
Genes
HSA: 6611(SMS)
PTR: 107966193(SMS) 739762
PPS: 100974711 100989256(SMS)
GGO: 101136287(SMS)
PON: 100447565 100455032(SMS)
NLE: 100592294(SMS) 100603217
MCC: 698179(SMS)
MCF: 102139114(SMS)
CSAB: 103231701(SMS)
RRO: 104676688(SMS)
RBB: 108512250
CJC: 100411404(SMS)
SBQ: 101037456(SMS)
MMU: 20603(Sms)
MCAL: 110287180(Sms) 110292244
MPAH: 110313434(Sms) 110326795
RNO: 363469(Sms)
MUN: 110539961(Sms)
CGE: 100753198(Sms)
NGI: 103730144(Sms)
HGL: 101696715(Sms) 101718865
CCAN: 109685258(Sms) 109685259
OCU: 100340020(SMS)
CFA: 480861(SMS)
VVP: 112916263 112919114(SMS)
AML: 100469558(SMS)
UMR: 103668176(SMS)
UAH: 113242233(SMS)
ORO: 101364730(SMS) 101371201
ELK: 111150447
FCA: 101090842(SMS)
PTG: 102954471(SMS)
PPAD: 109257443(SMS)
AJU: 106968260(SMS)
BTA: 615950(SMS)
BOM: 102270205 102283485(SMS)
BIU: 109554942(SMS) 109559006
BBUB: 102399518(SMS)
CHX: 102190676(SMS)
OAS: 101107419(SMS) 101112287
SSC: 100153052(SMS)
CFR: 102512656(SMS)
CDK: 105105052(SMS)
BACU: 103019290(SMS)
LVE: 103068984
OOR: 101272903(SMS)
DLE: 111167517(SMS)
PCAD: 102987295(SMS)
ECB: 100051857(SMS)
EPZ: 103566846(SMS)
EAI: 106835513(SMS)
MYB: 102251500 102257010(SMS)
MYD: 102760281(SMS)
MNA: 107526796(SMS)
HAI: 109395813(SMS)
DRO: 112313352(SMS)
PALE: 102896435(SMS)
RAY: 107521441(SMS)
MJV: 108396545(SMS)
LAV: 100658418(SMS)
TMU: 101354696
MDO: 100012760(SMS)
SHR: 100928879(SMS)
PCW: 110210823(SMS)
OAA: 100083114(SMS)
GGA: 418602(SMS)
MGP: 100549711(SMS)
CJO: 107324967(SMS)
NMEL: 110404540(SMS)
APLA: 101791698(SMS)
ACYG: 106037821(SMS)
TGU: 100228014(SMS)
LSR: 110483279(SMS)
SCAN: 103815851(SMS)
GFR: 102034236(SMS)
FAB: 101806851(SMS)
PHI: 102114400(SMS)
PMAJ: 107201826(SMS)
CCAE: 111922892(SMS)
CCW: 104686193(SMS)
ETL: 114067188(SMS)
FPG: 101922863(SMS)
FCH: 102049429(SMS)
CLV: 102096362(SMS)
EGZ: 104135174(SMS)
NNI: 104022508(SMS)
ACUN: 113478646
PADL: 103914492(SMS)
AAM: 106492122(SMS)
ASN: 102388291(SMS)
AMJ: 102559699(SMS)
PSS: 102445830(SMS)
CMY: 102933684(SMS)
CPIC: 101931607(SMS)
ACS: 100552713(sms) 100561005
PVT: 110076724(SMS)
PBI: 103049999(SMS)
PMUR: 107286125(SMS)
TSR: 106553354(SMS)
PMUA: 114596224(SMS)
GJA: 107120288(SMS)
XLA: 108708014(sms.L)
XTR: 100497747(sms)
NPR: 108791842(SMS)
DRE: 80872(sms)
IPU: 108279239(sms)
PHYP: 113541383(sms)
AMEX: 103023143(sms)
EEE: 113575324(sms)
TRU: 101072716(sms)
LCO: 104924594(sms)
NCC: 104965977(sms)
MZE: 101475695(sms)
ONL: 100708530(sms)
OLA: 101166897(sms)
XMA: 102233412(sms)
XCO: 114153519(sms)
PRET: 103475438(sms)
CVG: 107086975(sms)
NFU: 107386402(sms)
KMR: 108236978(sms)
ALIM: 106514045(sms)
AOCE: 111567113(sms)
CSEM: 103395717(sms)
POV: 109628585(sms)
LCF: 108893544(sms)
SDU: 111234621(sms)
SLAL: 111666195(sms)
HCQ: 109517965(sms)
BPEC: 110158443(sms)
MALB: 109959604(sms)
SASA: 100195133(spsy) 106603082
ELS: 105010858(sms)
SFM: 108939723(sms)
PKI: 111860978(sms)
LCM: 102363084(SMS)
CMK: 103189993(sms)
RTP: 109931901(sms)
CIN: 100184953
APLC: 110984481
DME: Dmel_CG4300(Sms)
DER: 6545024
DSE: 6605422
DSI: Dsimw501_GD12732(Dsim_GD12732)
DAN: 6507617
DSR: 110179980
DPE: 6596081
DMN: 108152781
DWI: 6645203
DAZ: 108614587
DNV: 108652249
DHE: 111598765
DVI: 6623526
MDE: 101896722
LCQ: 111677486
AAG: 5570348
AME: 410080
BIM: 100742708
BTER: 100647449
CCAL: 108622646
OBB: 114878120
SOC: 105201107
MPHA: 105832350
AEC: 105145851
ACEP: 105618948
PBAR: 105434139
VEM: 105570564
HST: 105184220
DQU: 106740768
CFO: 105258881
LHU: 105667455
PGC: 109857572
OBO: 105283669
PCF: 106790811
NVI: 100116075
CSOL: 105366297
MDL: 103571989
TCA: 656524
DPA: 109542993
ATD: 109600146
NVL: 108563491
BMOR: 101742636
BMAN: 114241374
PMAC: 106710981
PRAP: 110997871
HAW: 110374554
TNL: 113502268
BTAB: 109032705
CLEC: 106662819
ZNE: 110837290
TUT: 107372126
DPTE: 113796146
CSCU: 111623623
PTEP: 107447974
PCAN: 112556767
MYI: 110453256
NVE: 5516689
SCE: YLR146C(SPE4)
KMX: KLMA_50519(SPE4)
NCS: NCAS_0C03110(NCAS0C03110)
NDI: NDAI_0G02420(NDAI0G02420)
TPF: TPHA_0A01420(TPHA0A01420)
TBL: TBLA_0A04140(TBLA0A04140)
TDL: TDEL_0F04780(TDEL0F04780)
KAF: KAFR_0H02120(KAFR0H02120)
CAL: CAALFM_C113330CA(CaO19.4960)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7546290
  Authors
Korhonen VP, Halmekyto M, Kauppinen L, Myohanen S, Wahlfors J, Keinanen T, Hyvonen T, Alhonen L, Eloranta T, Janne J
  Title
Molecular cloning of a cDNA encoding human spermine synthase.
  Journal
DNA Cell Biol 14:841-7 (1995)
DOI:10.1089/dna.1995.14.841
  Sequence
[hsa:6611]
Reference
PMID:9573363
  Authors
Hamasaki-Katagiri N, Katagiri Y, Tabor CW, Tabor H
  Title
Spermine is not essential for growth of Saccharomyces cerevisiae: identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant.
  Journal
Gene 210:195-201 (1998)
DOI:10.1016/s0378-1119(98)00027-4
  Sequence
[sce:YLR146C]
Reference
  Authors
Pegg AE, Michael AJ
  Title
Spermine synthase.
  Journal
Cell Mol Life Sci 67:113-21 (2010)
DOI:10.1007/s00018-009-0165-5

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