KEGG   ORTHOLOGY: K00804Help
Entry
K00804                      KO                                     

Name
GGPS1
Definition
geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]
Pathway
ko00900  Terpenoid backbone biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01130  Biosynthesis of antibiotics
Module
M00367  C10-C20 isoprenoid biosynthesis, non-plant eukaryotes
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.1  dimethylallyltranstransferase
     K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
    2.5.1.10  (2E,6E)-farnesyl diphosphate synthase
     K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
    2.5.1.29  geranylgeranyl diphosphate synthase
     K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
Prenyltransferases [BR:ko01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   K00804  GGPS1; geranylgeranyl diphosphate synthase, type III
BRITE hierarchy
Other DBs
RN: R01658 R02003 R02061
COG: COG0142
GO: 0004161 0004337 0004311
Genes
HSA: 9453(GGPS1)
PTR: 100610192(GGPS1)
PPS: 100978959(GGPS1)
GGO: 101138399(GGPS1)
PON: 100444405(GGPS1)
NLE: 100589624(GGPS1)
MCC: 100425248(GGPS1)
MCF: 102115535(GGPS1)
CSAB: 103230796(GGPS1)
RRO: 104679169(GGPS1)
RBB: 108522207(GGPS1)
CJC: 100411975(GGPS1)
SBQ: 101030657(GGPS1)
MMU: 14593(Ggps1)
MCAL: 110308036(Ggps1)
MPAH: 110333828(Ggps1)
RNO: 291211(Ggps1)
MUN: 110558130(Ggps1)
CGE: 100767405(Ggps1)
NGI: 103745123(Ggps1)
HGL: 101698516(Ggps1)
CCAN: 109692621(Ggps1)
OCU: 100340259(GGPS1)
TUP: 102477912 102496659(GGPS1)
CFA: 479198(GGPS1)
VVP: 112917731 112927367(GGPS1)
AML: 100473588(GGPS1)
UMR: 103661894(GGPS1)
UAH: 113259002(GGPS1)
ORO: 101370952(GGPS1)
ELK: 111160525
FCA: 101082438(GGPS1)
PTG: 102952368(GGPS1)
PPAD: 109248883(GGPS1)
AJU: 106982555(GGPS1)
BTA: 780882(GGPS1)
BOM: 102280246(GGPS1)
BIU: 109553875(GGPS1)
BBUB: 102402997(GGPS1)
CHX: 102169552(GGPS1)
OAS: 101114414(GGPS1)
SSC: 100739526(GGPS1)
CFR: 102503638(GGPS1)
CDK: 105088831(GGPS1) 116149599
BACU: 103017222(GGPS1)
LVE: 103083669(GGPS1)
OOR: 101270381(GGPS1) 101270983
DLE: 111163940(GGPS1) 111165604
PCAD: 102979416(GGPS1)
ECB: 100050954(GGPS1)
EPZ: 103547684(GGPS1)
EAI: 106834703(GGPS1)
MYB: 102260376(GGPS1)
MYD: 102771057(GGPS1)
MNA: 107527182(GGPS1)
HAI: 109387736(GGPS1)
DRO: 112306046(GGPS1)
PALE: 102888929(GGPS1)
RAY: 107520046(GGPS1)
MJV: 108408921(GGPS1)
LAV: 100663324(GGPS1)
TMU: 101358569
MDO: 100021237(GGPS1)
SHR: 100918636(GGPS1)
PCW: 110217850(GGPS1)
OAA: 100081573(GGPS1)
GGA: 427092(GGPS1)
MGP: 100551404(GGPS1)
CJO: 107311374(GGPS1)
NMEL: 110396189(GGPS1)
APLA: 101801532(GGPS1)
ACYG: 106048792(GGPS1)
TGU: 100232753(GGPS1)
LSR: 110468869(GGPS1)
SCAN: 103818518(GGPS1)
GFR: 102035974(GGPS1)
FAB: 101814017(GGPS1)
PHI: 102113480(GGPS1)
PMAJ: 107201642(GGPS1)
CCAE: 111926854(GGPS1)
CCW: 104684288(GGPS1)
ETL: 114066551(GGPS1)
FPG: 101911343(GGPS1)
FCH: 102045849(GGPS1)
CLV: 102094057(GGPS1)
EGZ: 104131017(GGPS1)
NNI: 104019872(GGPS1)
ACUN: 113478236(GGPS1)
PADL: 103921234(GGPS1)
AAM: 106486810(GGPS1)
ASN: 102373119(GGPS1)
AMJ: 102571306(GGPS1)
PSS: 102457955(GGPS1)
CMY: 102935186(GGPS1)
CPIC: 101934501(GGPS1)
ACS: 100565156(ggps1)
PVT: 110075618(GGPS1)
PBI: 103064915(GGPS1)
PMUR: 107288311(GGPS1)
TSR: 106538178(GGPS1)
GJA: 107117724(GGPS1)
XLA: 100049104(ggps1.L) 108717904(ggps1.S)
XTR: 549876(ggps1)
NPR: 108799798(GGPS1)
DRE: 336798(ggps1)
SANH: 107667013(ggps1) 107691209
SGH: 107569429(ggps1)
CCAR: 109105124(ggps1) 109111450
IPU: 108263030(ggps1)
PHYP: 113541961(ggps1)
AMEX: 103030213(ggps1)
EEE: 113577748(ggps1)
LCO: 104934549(ggps1)
NCC: 104960300(ggps1)
MZE: 101477767(ggps1)
ONL: 100693505(ggps1)
OLA: 101169557(ggps1)
XMA: 102233815(ggps1)
XCO: 114137543(ggps1)
PRET: 103477262(ggps1)
CVG: 107087813(ggps1)
NFU: 107375433(ggps1)
KMR: 108240652(ggps1)
ALIM: 106515876(ggps1)
AOCE: 111573732(ggps1)
CSEM: 103387619(ggps1)
POV: 109642027(ggps1)
LCF: 108885800(ggps1)
SDU: 111220747(ggps1)
SLAL: 111659017(ggps1)
HCQ: 109516188(ggps1)
BPEC: 110157161(ggps1)
MALB: 109962000(ggps1)
SASA: 100196754(ggps1)
OTW: 112237454(ggps1)
SALP: 112071950(ggps1)
ELS: 105006090(ggps1)
SFM: 108933566(ggps1)
PKI: 111856365(ggps1)
LCM: 102358313(GGPS1)
CMK: 103178877(ggps1)
RTP: 109918358(ggps1)
SPU: 575576
APLC: 110984925
SKO: 100371847
DME: Dmel_CG8593(qm)
DER: 6544432
DSI: Dsimw501_GD14008(Dsim_GD14008)
DSR: 110190817
DPE: 6602963
DMN: 108152067
DWI: 6639270
DAZ: 108613653
DNV: 108651419
DHE: 111601038
MDE: 101901793
LCQ: 111688489
AAG: 5565667
AME: 727189
BIM: 100741327
BTER: 100646723
CCAL: 108630853
OBB: 114878586
PBAR: 105433240
HST: 105180575
DQU: 106748661
LHU: 105673230
PGC: 109860942
PCF: 106784845
NVI: 100122074
CSOL: 105368212
MDL: 103570822
TCA: 660091
DPA: 109541376
ATD: 109595752
NVL: 108564043
BMOR: 101737879
BMAN: 114245250
PMAC: 106717826
HAW: 110383989
TNL: 113500426
PXY: 105388892
API: 100161650
AGS: 114126189
RMD: 113552148
BTAB: 109034594
CLEC: 106667088
ZNE: 110836650
TUT: 107363541
DPTE: 113790825
CSCU: 111631219
PTEP: 107441872
BMY: Bm1_07565
PCAN: 112575826
CRG: 105331834
MYI: 110450576
OBI: 106872435
SHX: MS3_09190
EGL: EGR_03356
EPA: 110236964
ADF: 107329885
AMIL: 114965437
PDAM: 113666942
SPIS: 111341123
AQU: 100640281
SCE: YPL069C(BTS1)
ERC: Ecym_1170
KMX: KLMA_10752(BTS1)
NCS: NCAS_0C02140(NCAS0C02140)
NDI: NDAI_0E02850(NDAI0E02850)
TPF: TPHA_0I01940(TPHA0I01940)
TBL: TBLA_0A00600(TBLA0A00600)
TDL: TDEL_0B03100(TDEL0B03100)
KAF: KAFR_0E00960(KAFR0E00960)
PIC: PICST_46658(BTS1)
CAL: CAALFM_C503620WA(BTS1)
NCR: NCU01427(al-3)
NTE: NEUTE1DRAFT115818(NEUTE1DRAFT_115818)
SMP: SMAC_06570(putative al3)
MGR: MGG_00758
SSCK: SPSK_05240
CMT: CCM_03697
MBE: MBM_04689
ANG: ANI_1_2028074(An08g06160) ANI_1_992034(An03g00860)
ABE: ARB_03622
TVE: TRV_03235
CNE: CNI00090
CNB: CNBH0100
ABP: AGABI1DRAFT112964(AGABI1DRAFT_112964)
ABV: AGABI2DRAFT192934(AGABI2DRAFT_192934)
MGL: MGL_3268
MRT: MRET_2425
DDI: DDB_G0293588(ggps1)
DFA: DFA_03765(ggps1)
FCY: FRACYDRAFT_287526(GGPPS)
TPS: THAPSDRAFT_264430(GGPS3)
SPAR: SPRG_06894
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7665600
  Authors
Jiang Y, Proteau P, Poulter D, Ferro-Novick S
  Title
BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae.
  Journal
J Biol Chem 270:21793-9 (1995)
DOI:10.1074/jbc.270.37.21793
Reference
  Authors
Kainou T, Kawamura K, Tanaka K, Matsuda H, Kawamukai M
  Title
Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human.
  Journal
Biochim Biophys Acta 1437:333-40 (1999)
DOI:10.1016/S1388-1981(99)00028-1
Reference
  Authors
Vandermoten S, Haubruge E, Cusson M
  Title
New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition.
  Journal
Cell Mol Life Sci 66:3685-95 (2009)
DOI:10.1007/s00018-009-0100-9

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