KEGG   ORTHOLOGY: K00827
Entry
K00827                      KO                                     
Symbol
AGXT2
Name
alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40]
Pathway
map00250  Alanine, aspartate and glutamate metabolism
map00260  Glycine, serine and threonine metabolism
map00270  Cysteine and methionine metabolism
map00280  Valine, leucine and isoleucine degradation
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
Reaction
R00369  L-alanine:glyoxylate aminotransferase
R00372  glycine:2-oxoglutarate aminotransferase
R02050  (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase
R10992  L-alanine:2-oxobutanoate aminotransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
   00260 Glycine, serine and threonine metabolism
    K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
   00270 Cysteine and methionine metabolism
    K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
   00280 Valine, leucine and isoleucine degradation
    K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.40  (R)-3-amino-2-methylpropionate---pyruvate transaminase
     K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
    2.6.1.44  alanine---glyoxylate transaminase
     K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class III
   K00827  AGXT2; alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase
Other DBs
GO: 0008453 0047305
Genes
HSA: 64902(AGXT2)
PTR: 471573(AGXT2)
PPS: 100982568(AGXT2)
GGO: 101147587(AGXT2)
PON: 100171524(AGXT2)
PPYG: 129036092(AGXT2)
NLE: 100607531(AGXT2)
HMH: 116456813(AGXT2)
SSYN: 129464566(AGXT2)
MCC: 699250(AGXT2)
MCF: 102140666(AGXT2)
MTHB: 126956688
MNI: 105473059(AGXT2)
CSAB: 103215117(AGXT2)
CATY: 105583414(AGXT2)
PANU: 101025018(AGXT2)
TGE: 112626357(AGXT2)
MLEU: 105531239(AGXT2)
RRO: 104678746(AGXT2)
RBB: 108543800(AGXT2)
TFN: 117065012(AGXT2)
PTEH: 111545528(AGXT2)
CANG: 105513478(AGXT2)
CJC: 100403023(AGXT2)
SBQ: 101045858(AGXT2)
CIMI: 108317656(AGXT2)
ANAN: 105722477(AGXT2)
CSYR: 103264977(AGXT2)
MMUR: 105867781(AGXT2)
LCAT: 123648239(AGXT2)
PCOQ: 105807191(AGXT2)
OGA: 100940834(AGXT2)
MMU: 268782(Agxt2)
MCAL: 110310555(Agxt2)
MPAH: 110328982(Agxt2)
RNO: 83784(Agxt2)
MCOC: 116083222(Agxt2)
ANU: 117723954(Agxt2)
MUN: 110566620(Agxt2)
CGE: 100759906(Agxt2)
MAUA: 101838780(Agxt2)
PROB: 127220642(Agxt2)
PLEU: 114710800(Agxt2)
MORG: 121432992(Agxt2)
MFOT: 126499704
AAMP: 119808770(Agxt2)
NGI: 103735910(Agxt2)
HGL: 101714498(Agxt2)
CPOC: 100714301(Agxt2)
CCAN: 109690881(Agxt2)
DORD: 105987377(Agxt2)
DSP: 122116999(Agxt2)
PLOP: 125367682(Agxt2)
NCAR: 124986522
MMMA: 107151125(Agxt2)
OCU: 100352336
OPI: 101519119(AGXT2)
TUP: 102501713(AGXT2)
GVR: 103608437(AGXT2)
CFA: 612589(AGXT2)
CLUD: 112652638(AGXT2)
VVP: 112908610(AGXT2)
VLG: 121487429(AGXT2)
NPO: 129509877(AGXT2)
AML: 100482092(AGXT2)
UMR: 103664720(AGXT2)
UAH: 113260880(AGXT2)
UAR: 123785468(AGXT2)
ELK: 111141161
LLV: 125100800
MPUF: 101688685(AGXT2)
MNP: 132028241(AGXT2)
MLK: 131831648(AGXT2)
NVS: 122895443(AGXT2)
ORO: 101375130(AGXT2)
EJU: 114204858(AGXT2)
ZCA: 113929184(AGXT2)
NSU: 110585991(AGXT2)
LWW: 102746978(AGXT2)
FCA: 101097947(AGXT2)
PYU: 121041672(AGXT2)
PCOO: 112860450(AGXT2)
PBG: 122494694(AGXT2)
PVIV: 125164813(AGXT2)
LRUF: 124510283
PTG: 102966139(AGXT2)
PPAD: 109267716(AGXT2)
PUC: 125935292
AJU: 106980604
HHV: 120242473(AGXT2)
BTA: 521553(AGXT2)
BOM: 102269782(AGXT2)
BIU: 109575007(AGXT2)
BBUB: 102415414(AGXT2)
BBIS: 104998563(AGXT2)
CHX: 102176828(AGXT2)
OAS: 101111660(AGXT2)
BTAX: 128066209(AGXT2)
ODA: 120879332(AGXT2)
CCAD: 122454584(AGXT2)
MBEZ: 129553099(AGXT2)
SSC: 100513890(AGXT2)
CFR: 102515152(AGXT2)
CBAI: 105069421(AGXT2)
CDK: 105087007(AGXT2)
VPC: 102538895(AGXT2)
BACU: 103010921(AGXT2)
BMUS: 118893637(AGXT2)
LVE: 103080731(AGXT2)
OOR: 101275910(AGXT2)
DLE: 111187642(AGXT2)
PCAD: 102974755(AGXT2)
PSIU: 116751363(AGXT2)
NASI: 112406009(AGXT2)
ECB: 100053849(AGXT2)
EPZ: 103545309(AGXT2)
EAI: 106824782(AGXT2)
MYB: 102239222(AGXT2)
MYD: 102773052(AGXT2)
MMYO: 118656733(AGXT2)
MLF: 102424294(AGXT2)
PKL: 118703611(AGXT2)
EFUS: 103298080(AGXT2)
MNA: 107546352(AGXT2)
DRO: 112321148(AGXT2)
SHON: 118998768(AGXT2)
AJM: 119037022(AGXT2)
PDIC: 114508826(AGXT2)
PHAS: 123824867(AGXT2)
MMF: 118642404(AGXT2)
PPAM: 129078987(AGXT2)
HAI: 109385510(AGXT2)
RFQ: 117025204(AGXT2)
PALE: 102888844(AGXT2)
PGIG: 120586202(AGXT2)
PVP: 105305880(AGXT2)
RAY: 107509702(AGXT2)
MJV: 108405850(AGXT2)
TOD: 119261123(AGXT2)
SARA: 101546708(AGXT2)
SETR: 126000012(AGXT2)
LAV: 100668434(AGXT2)
TMU: 101347029
ETF: 101663774(AGXT2)
DNM: 101445866(AGXT2)
MDO: 100020759(AGXT2)
GAS: 123237446(AGXT2)
SHR: 100917044(AGXT2)
AFZ: 127556491
PCW: 110214612(AGXT2)
TVP: 118849226(AGXT2)
OAA: 100078063(AGXT2)
GGA: 431666(AGXT2)
PCOC: 116238630(AGXT2)
MGP: 100541842(AGXT2)
CJO: 107305776(AGXT2)
TPAI: 128074565(AGXT2)
LMUT: 125686888(AGXT2)
NMEL: 110389481(AGXT2)
APLA: 101799853(AGXT2)
ACYG: 106036349(AGXT2)
CATA: 118256639(AGXT2)
AFUL: 116500789(AGXT2)
TGU: 100230972
LSR: 110482591(AGXT2)
SCAN: 103822879(AGXT2)
PMOA: 120502503(AGXT2)
OTC: 121343622(AGXT2)
PRUF: 121365751(AGXT2)
GFR: 102033340(AGXT2)
FAB: 101810573(AGXT2)
OMA: 130264800(AGXT2)
PHI: 102109437(AGXT2)
PMAJ: 107198191(AGXT2)
CCAE: 111941074(AGXT2)
CCW: 104686756(AGXT2)
CBRC: 103612921(AGXT2)
ETL: 114066149(AGXT2)
ZAB: 102070123(AGXT2)
ZLE: 135459808(AGXT2)
ACHL: 103798198(AGXT2)
SVG: 106852679(AGXT2)
MMEA: 130572764(AGXT2)
HRT: 120765939(AGXT2)
FPG: 101911080(AGXT2)
FCH: 102052632(AGXT2)
CLV: 102087277(AGXT2)
EGZ: 104133922(AGXT2)
NNI: 104014002(AGXT2)
PCRI: 104031318(AGXT2)
PLET: 104622320(AGXT2)
EHS: 104512513(AGXT2)
PCAO: 104042149(AGXT2)
ACUN: 113489545(AGXT2)
TALA: 104358771(AGXT2)
PADL: 103912227(AGXT2)
AFOR: 103903911(AGXT2)
ACHC: 115336940(AGXT2)
HALD: 104310530(AGXT2)
HLE: 104830618(AGXT2)
AGEN: 126036528
GCL: 127027591
CCRI: 104163118(AGXT2)
CSTI: 104562530(AGXT2)
CMAC: 104473332(AGXT2)
MUI: 104537498(AGXT2)
FGA: 104069511(AGXT2)
GSTE: 104255249(AGXT2)
LDI: 104339983(AGXT2)
MNB: 103773778(AGXT2)
OHA: 104337752(AGXT2)
NNT: 104413658(AGXT2)
SHAB: 115619650(AGXT2)
DPUB: 104303470(AGXT2)
PGUU: 104457847(AGXT2)
ACAR: 104517867(AGXT2)
CPEA: 104398626(AGXT2)
AVIT: 104267461(AGXT2)
CVF: 104295014(AGXT2)
RTD: 128902489(AGXT2)
CUCA: 104063847(AGXT2)
TEO: 104373803(AGXT2)
BRHI: 104492715(AGXT2)
AAM: 106499541(AGXT2)
AROW: 112976243(AGXT2)
NPD: 112946243(AGXT2)
TGT: 104570698(AGXT2) 104572218
DNE: 112982174(AGXT2)
SCAM: 104147780(AGXT2)
ASN: 102375742(AGXT2)
AMJ: 102559340(AGXT2)
CPOO: 109307674(AGXT2)
GGN: 109298138(AGXT2)
PSS: 102449032(AGXT2)
CMY: 102930944(AGXT2)
CCAY: 125636737(AGXT2)
DCC: 119855626(AGXT2)
CPIC: 101937486(AGXT2)
TST: 117878828(AGXT2)
CABI: 116833368(AGXT2)
MRV: 120407376(AGXT2)
ACS: 100565387(agxt2)
ASAO: 132766920(AGXT2)
PVT: 110080093(AGXT2)
SUND: 121921476(AGXT2)
PBI: 103060614(AGXT2)
PMUR: 107296961(AGXT2) 107299675
CTIG: 120310012(AGXT2)
TSR: 106544287(AGXT2) 106555888
PGUT: 117679997(AGXT2)
APRI: 131191180(AGXT2)
PTEX: 113444825(AGXT2)
NSS: 113411375(AGXT2)
VKO: 123024135(AGXT2)
PMUA: 114606480(AGXT2)
PRAF: 128423485(AGXT2)
ZVI: 118077134(AGXT2)
HCG: 128348125(AGXT2)
GJA: 107107502(AGXT2)
STOW: 125436899(AGXT2)
EMC: 129334440(AGXT2)
XLA: 108705425(agxt2.S) 108718414(agxt2.L)
XTR: 100491739(agxt2)
NPR: 108792653(AGXT2)
RTEM: 120927521(AGXT2)
BBUF: 120992187(AGXT2)
BGAR: 122924887(AGXT2)
MUO: 115462930(AGXT2)
GSH: 117354957(AGXT2)
DRE: 619269(agxt2)
SANH: 107662137
SGH: 107600890
CCAR: 109069820(agxt2)
CAUA: 113038862(agxt2) 113063715
PTET: 122326297(agxt2)
LROH: 127152378(agxt2)
OMC: 131528318(agxt2)
PPRM: 120490753(agxt2)
RKG: 130090775(agxt2)
MAMB: 125252092(agxt2)
TROS: 130570453(agxt2)
TDW: 130407894(agxt2)
MANU: 129423162(agxt2)
IPU: 108279281
IFU: 128622524(agxt2)
PHYP: 113535665(agxt2)
SMEO: 124398429(agxt2)
TFD: 113653544(agxt2)
TVC: 132860296(agxt2)
TRN: 134330195(agxt2)
AMEX: 103047265(agxt2)
CMAO: 118820452(agxt2)
EEE: 113584570(agxt2)
CHAR: 105911486(agxt2)
TRU: 101075075(agxt2)
TFS: 130517485(agxt2)
TBEN: 117476341(agxt2) 117476344
CGOB: 115016801(agxt2)
GACU: 117538951(agxt2) 117539284
EMAC: 134868217 134868218(agxt2)
SLUC: 116062799(agxt2)
ECRA: 117959251(agxt2)
ESP: 116704419(agxt2)
PFLV: 114571143(agxt2)
CLUM: 117740433(agxt2)
PSWI: 130205303(agxt2)
MSAM: 119914033(agxt2)
MZE: 101477079(agxt2)
OAU: 116331688
OLA: 111948298(agxt2)
OML: 112163412(agxt2)
XMA: 102217588(agxt2)
XCO: 114150170(agxt2)
XHE: 116724194(agxt2)
PRET: 103473873(agxt2)
PFOR: 103142735(agxt2)
PLAI: 106952443(agxt2)
PMEI: 106918658(agxt2)
GAF: 122819621(agxt2)
PPRL: 129366531(agxt2)
CVG: 107085798(agxt2)
CTUL: 119776602(agxt2)
GMU: 124872599(agxt2)
NFU: 107374696(agxt2)
KMR: 108231105(agxt2)
ALIM: 106518182(agxt2)
NWH: 119425054(agxt2)
AOCE: 111578671(agxt2) 111587894
CSEM: 103390290(agxt2)
POV: 109626465(agxt2)
SSEN: 122758137(agxt2)
HHIP: 117771680(agxt2)
HSP: 118125655(agxt2)
PPLT: 128425008(agxt2)
SMAU: 118284476(agxt2)
SDU: 111234697(agxt2) 111234704
SLAL: 111664750 111664751(agxt2)
HCQ: 109523626(agxt2)
SSCV: 125979459
SBIA: 133490798(agxt2)
PEE: 133413800(agxt2)
PTAO: 133489802(agxt2)
BPEC: 110160563(agxt2)
MALB: 109960590(agxt2)
BSPL: 114867407(agxt2)
SASA: 106568486(agxt2)
STRU: 115149465(agxt2)
OTW: 112257351(agxt2)
OMY: 110536779(agxt2)
OGO: 123999388(agxt2)
ONE: 115106020(agxt2)
OKI: 109892312(agxt2)
OKE: 118391571(agxt2)
SALP: 111980518(agxt2)
SNH: 120044878(agxt2)
CCLU: 121573417(agxt2)
ELS: 105007583(agxt2)
SFM: 108935619(agxt2)
PKI: 111852579(agxt2)
AANG: 118213290(agxt2)
LOC: 102682826(agxt2)
PSPA: 121304721(agxt2)
ARUT: 117420681(agxt2)
PSEX: 120527283(agxt2)
LCM: 102356225(AGXT2)
HOC: 132829725(agxt2)
LERI: 129715313(agxt2)
PMRN: 116955742
LRJ: 133359058(AGXT2)
BFO: 118417587
BBEL: 109473515
CIN: 100178847
SPU: 594821
LPIC: 129253875
APLC: 110989783
ARUN: 117305989
AJC: 117123045
DME: Dmel_CG11241(CG11241)
DER: 6544107
DSE: 6616589
DSI: Dsimw501_GD12056(Dsim_GD12056)
DAN: 6506089
DSR: 110190421
DPO: 4812476
DPE: 6603439
DMN: 108152459
DWI: 6645706
DGR: 6557381
DNV: 115563732
DHE: 111595344
DVI: 6622852
CCAT: 101451194
BOD: 106623603
BDR: 105227212
AOQ: 129240970
MDE: 101893078
SCAC: 106091501
LCQ: 111682457
LSQ: 119612252
GFS: 119632010
ECOE: 129939156
CLON: 129610290
HIS: 119647621
AGA: 1280310
ACOZ: 120955850
AARA: 120901399
AMER: 121600474
ASTE: 118503350
AFUN: 125771803
AMOU: 128307162
AALI: 118465825
AAG: 5565436
ASUA: 134224271
CPII: 120422215
CNS: 116341035
BCOO: 119072302
AME: 100576186
ACER: 107995955
ALAB: 122718087
ADR: 102677809
AFLR: 100871018
BIM: 100748967
BBIF: 117214042
BVK: 117236331
BVAN: 117166801
BTER: 100645336
BAFF: 126917054
BPYO: 122572915
BPAS: 132907280
FVI: 122531703
CCAL: 108624048
OBB: 114879990
OLG: 117610316
MGEN: 117229903
NMEA: 116434807
CGIG: 122402511
PCF: 106791427
PFUC: 122515301
VPS: 122635418
VCRB: 124421743
VVE: 124952467
NVI: 100123739
CSOL: 105366494
TPRE: 106656953
LHT: 122512797
LBD: 127277953
MDL: 103568860
CGLO: 123258419
FAS: 105273947
DAM: 107036613
AGIF: 122857736
CINS: 118066921
VCAN: 122414127
CCIN: 107267829
DSM: 124405667
NPT: 124213401
NFB: 124175554
NLO: 107217797
NVG: 124296988
AROA: 105689693
TCA: 658321
DPA: 109536139
SOY: 115887837
AGRG: 126735200
ATD: 109599134
CSET: 123314975
AGB: 108905228
LDC: 111503562
DVV: 126890078
NVL: 108565425
PPYR: 116175059
OTU: 111421259
MSEX: 115453913
BANY: 112046799
MJU: 123868509
NIQ: 126774359
VCD: 124536121
MCIX: 123659963
PRAP: 111003467
PBX: 123715367
PNAP: 125057570
ZCE: 119840696
CCRC: 123694349
LSIN: 126965340
AAGE: 121739032
HAW: 110375501
HZE: 124635202
TNL: 113498037
SLIU: 111359232
OFU: 114356349
ATRA: 106133390
GMW: 113521324
PXY: 105394913
PGW: 126372489
LGLY: 125231733
CCRN: 123297884
API: 100163196
DNX: 107162134
AGS: 114130714
RMD: 113556264
ACOO: 126833877
DVT: 126908714
BTAB: 109036563
DCI: 103510603
CLEC: 106663150
HHAL: 106677667
NLU: 111054011
MQU: 129004308
FOC: 113212569
TPAL: 117645061
ZNE: 110828279
CSEC: 111866740
BROR: 134537734
IEL: 124164247
FCD: 110855892
DMK: 116918821
DPZ: 124312112
PVM: 113819666
PJA: 122266894
PCHN: 125048334
PMOO: 119579718
HAME: 121873292
PCLA: 123769161
CQD: 128690106
PTRU: 123507864
MNZ: 135217193
HAZT: 108676415
EAF: 111702699
LSM: 121119659
TCF: 131878178
PPOI: 119099417
DSV: 119435966
RSAN: 119404549
RMP: 119187480
VDE: 111249169
TUT: 107366508
DFR: 124500037
CSCU: 111630245
PTEP: 107439021
ABRU: 129959118
SDM: 118181588
LPOL: 106463086
PMEO: 129581659
CEL: CELE_T09B4.8(T09B4.8)
CBR: CBG_12888
PVUL: 126816710
PCAN: 112577308
BGT: 106058632
HRF: 124147410
CRG: 105338391
CANU: 128188489
CVN: 111135360
OED: 125667419
MYI: 110453623
PMAX: 117337550
MCAF: 127702387
MMER: 123549505
DPOL: 127845506
MAEA: 128243354
OBI: 106882838
OSN: 115216892
LJP: 135465659
LAK: 106163654
LLON: 135495454
NVE: 5506278
EPA: 110243940
ATEN: 116306337
AMIL: 114958147
PDAM: 113666683
SPIS: 111324760
DGT: 114517030
XEN: 124437530
HMG: 100197706
HSY: 130613780
RES: 135691333
AQU: 100631942
ATH: AT2G38400(AGT3) AT3G08860(PYD4) AT4G39660(AGT2)
CPAP: 110817186
LJA: Lj1g3v2444980.1(Lj1g3v2444980.1) Lj4g3v2800580.1(Lj4g3v2800580.1)
RCU: 8269354
DOSA: Os03t0171900-01(Os03g0171900) Os03t0338000-01(Os03g0338000) Os05t0475400-01(Os05g0475400)
PPP: 112287430
APRO: F751_4530
LLG: 44548918_01443(dgdA)
LCJ: NCTC11976_02502(dgdA)
LWA: SAMEA4504053_2397(dgdA_2)
RID: RIdsm_01011(dgdA)
PSAB: PSAB_01945
PRI: PRIO_0619
CBV: U729_2097
STED: SPTER_24020(argD_2)
TRA: Trad_1960
LCRE: Pla8534_41840(davT)
AAGG: ETAA8_48580(tpa)
PND: Pla175_14200(tpa)
AMOB: HG15A2_42190(dgdA)
 » show all
Reference
  Authors
Tamaki N, Sakata SF, Matsuda K
  Title
Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver.
  Journal
Methods Enzymol 324:376-89 (2000)
DOI:10.1016/S0076-6879(00)24247-X
  Sequence
[rno:83784]

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