KEGG   ORTHOLOGY: K00863
Entry
K00863                      KO                                     
Symbol
DAK, TKFC
Name
triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]
Pathway
map00051  Fructose and mannose metabolism
map00561  Glycerolipid metabolism
map00680  Methane metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map04622  RIG-I-like receptor signaling pathway
Module
M00344  Formaldehyde assimilation, xylulose monophosphate pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K00863  DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing)
  09102 Energy metabolism
   00680 Methane metabolism
    K00863  DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing)
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    K00863  DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    K00863  DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing)
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.28  triokinase
     K00863  DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing)
    2.7.1.29  glycerone kinase
     K00863  DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing)
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.15  FAD-AMP lyase (cyclizing)
     K00863  DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing)
Other DBs
RN: R01011 R01059
COG: COG2376
GO: 0050354 0004371 0034012
Genes
HSA: 26007(TKFC)
PTR: 466626(TKFC)
PPS: 100974411(TKFC)
GGO: 101128538(TKFC)
PON: 100439500(TKFC)
NLE: 100591351(TKFC)
MCC: 694117(TKFC)
MCF: 102140150(TKFC)
CSAB: 103234474(TKFC)
CATY: 105577598(TKFC)
PANU: 101002534(TKFC)
TGE: 112605798(TKFC)
RRO: 104679394(TKFC)
RBB: 108533618(TKFC)
TFN: 117079821(TKFC)
PTEH: 111524304(TKFC)
CJC: 100415031(TKFC)
SBQ: 101047818(DAK)
CSYR: 103249426(TKFC)
MMUR: 105878639(TKFC)
LCAT: 123641252(TKFC)
OGA: 100958217(TKFC)
MMU: 225913(Tkfc)
MCAL: 110285965(Tkfc)
MPAH: 110321557(Tkfc)
RNO: 361730(Tkfc)
MCOC: 116103559(Tkfc)
MUN: 110548073(Tkfc)
CGE: 100765605(Tkfc)
MAUA: 101840859(Tkfc)
PLEU: 114703419(Tkfc)
MORG: 121454394(Tkfc)
AAMP: 119807618(Tkfc)
NGI: 103724936(Tkfc)
HGL: 101710604(Tkfc)
CPOC: 100727199(Tkfc)
CCAN: 109687386(Tkfc)
DORD: 105995529(Tkfc)
DSP: 122104884(Tkfc)
NCAR: 124958727
OCU: 100344187(TKFC)
OPI: 101522524(TKFC)
TUP: 102491754(TKFC)
CFA: 483800(TKFC)
CLUD: 112659542(TKFC)
VVP: 112911058(TKFC)
VLG: 121501750(TKFC)
AML: 100471465(TKFC)
UMR: 103678225(TKFC)
UAH: 113246914(TKFC)
UAR: 123785113(TKFC)
ELK: 111150002
LLV: 125080047
MPUF: 101685667(TKFC)
ORO: 101369948(TKFC)
EJU: 114220283(TKFC)
ZCA: 113913494(TKFC)
MLX: 118015912(TKFC)
FCA: 101081330(TKFC)
PYU: 121043331(TKFC)
PBG: 122483850(TKFC)
PTG: 102958008(TKFC)
PPAD: 109246538(TKFC)
AJU: 106977860(TKFC)
HHV: 120246156(TKFC)
BTA: 512373(TKFC)
BOM: 102277749(TKFC)
BIU: 109554276(TKFC)
BBUB: 102414214(TKFC)
CHX: 102173368(TKFC)
OAS: 101106378(TKFC)
ODA: 120874529(TKFC)
CCAD: 122431317(TKFC)
SSC: 100520121(TKFC)
CFR: 102524457(TKFC)
CBAI: 105070100(DAK)
CDK: 105094884(TKFC)
VPC: 102525590(TKFC)
BACU: 103012192(TKFC)
LVE: 103087760(TKFC)
OOR: 101271651(TKFC)
DLE: 111183894(TKFC)
PCAD: 102994508
PSIU: 116757714(TKFC)
ECB: 100059639(TKFC)
EPZ: 103563966(TKFC)
EAI: 106847572(TKFC)
MYB: 102255909(TKFC)
MYD: 102760581(TKFC)
MMYO: 118649041(TKFC)
MLF: 102432614(TKFC)
MNA: 107527693(TKFC)
PKL: 118707307(TKFC)
HAI: 109389969(TKFC)
DRO: 112317204(TKFC)
SHON: 118996904(TKFC)
AJM: 119043692(TKFC)
PDIC: 114500274(TKFC)
PHAS: 123829292(TKFC)
MMF: 118628319(TKFC)
RFQ: 117029868(TKFC)
PALE: 102897271(TKFC)
PGIG: 120600872(TKFC)
PVP: 105297774(TKFC)
RAY: 107504751(TKFC)
MJV: 108392383(TKFC)
TOD: 119250057(TKFC)
SARA: 101537684(TKFC)
LAV: 100655773(TKFC)
TMU: 101349905
DNM: 101414022(TKFC)
MDO: 100029804(TKFC)
GAS: 123252053(TKFC)
SHR: 100932911(TKFC)
PCW: 110195388(TKFC)
OAA: 100076247(TKFC)
GGA: 426629(TKFC)
PCOC: 116243027(TKFC)
MGP: 100538423(TKFC)
CJO: 107314198(TKFC)
NMEL: 110400834(TKFC)
APLA: 101791561(TKFC)
AFUL: 116490150(TKFC)
TGU: 100225815(TKFC)
LSR: 110484949(TKFC)
SCAN: 103822267(TKFC)
PMOA: 120499593(TKFC)
OTC: 121340008(TKFC)
PRUF: 121355187(TKFC)
GFR: 102037738(TKFC)
FAB: 101813291(TKFC)
PHI: 102109793(TKFC)
PMAJ: 107206333(TKFC)
CCAE: 111930602(TKFC)
CCW: 104684142(TKFC)
CBRC: 103611844(TKFC)
ETL: 114063339(TKFC)
ZAB: 102061413(TKFC)
FPG: 101916728(TKFC)
FCH: 102056266(TKFC)
CLV: 102083757(TKFC)
NNI: 104009164(DAK)
TALA: 116961862(TKFC)
ACHC: 115351571(TKFC)
AAM: 106494896(TKFC)
AROW: 112960833(TKFC)
NPD: 112952734(TKFC)
DNE: 112988669(TKFC)
ASN: 102380822(TKFC)
AMJ: 102566051(TKFC)
PSS: 102458392(TKFC)
CMY: 102935253(TKFC)
CPIC: 101934870(TKFC)
TST: 117875988(TKFC)
CABI: 116822488(TKFC)
MRV: 120405166(TKFC)
ACS: 100553788(tkfc)
PVT: 110078319(TKFC)
SUND: 121934411(TKFC)
PBI: 103056665(TKFC)
PMUR: 107292666(TKFC)
TSR: 106550283(TKFC)
PGUT: 117667048(TKFC)
VKO: 123021300(TKFC)
PMUA: 114600735(TKFC)
ZVI: 118089224(TKFC)
GJA: 107121403(TKFC)
STOW: 125426790(TKFC)
XLA: 108715194(tkfc.S)
XTR: 779584(tkfc)
NPR: 108794171(TKFC)
RTEM: 120917247(TKFC)
BBUF: 120981095(TKFC)
BGAR: 122920796(TKFC)
DRE: 793926(tkfc)
SRX: 107731922
SANH: 107675501(tkfc)
SGH: 107595319(tkfc)
CCAR: 109093694(tkfc)
CAUA: 113052245(tkfc)
MAMB: 125265504(tkfc)
IPU: 108267727(tkfc)
PHYP: 113540118(tkfc)
SMEO: 124386696(tkfc)
TFD: 113635161(tkfc)
AMEX: 103037716(tkfc)
EEE: 113573484(tkfc)
TRU: 101066405(tkfc)
LCO: 109139822(tkfc)
CGOB: 115023703(tkfc)
ELY: 117246081(tkfc)
EFO: 125884432(tkfc)
PLEP: 121962471(tkfc)
SLUC: 116053149(tkfc)
ECRA: 117935026(tkfc)
PFLV: 114573915(tkfc)
GAT: 120823096(tkfc)
PPUG: 119222924(tkfc)
MSAM: 119913162(tkfc)
CUD: 121504646(tkfc)
ALAT: 119027000(tkfc)
MZE: 101472672(tkfc)
ONL: 100692489(tkfc)
OAU: 116323404(tkfc)
OLA: 101174800(tkfc)
OML: 112156166(tkfc)
XMA: 102222466(tkfc)
XCO: 114157350(tkfc)
XHE: 116733360(tkfc)
PRET: 103480605(tkfc)
PFOR: 103156773(tkfc)
PLAI: 106957675(tkfc)
PMEI: 106923242(tkfc)
GAF: 122820269(tkfc)
CVG: 107095500
CTUL: 119784393(tkfc)
GMU: 124880052(tkfc)
NFU: 107397385(tkfc)
KMR: 108249671(tkfc)
ALIM: 106519073(tkfc)
NWH: 119417194(tkfc)
AOCE: 111587749(tkfc)
MCEP: 125012353(tkfc)
CSEM: 103386061(tkfc)
POV: 109646508(tkfc)
SSEN: 122765914(tkfc)
HHIP: 117751863(tkfc)
HSP: 118102401(tkfc)
LCF: 108891958(tkfc)
SDU: 111233365(tkfc)
SLAL: 111657227(tkfc)
XGL: 120797148(tkfc)
HCQ: 109506957(tkfc)
MALB: 109974193(tkfc)
BSPL: 114866031(tkfc)
SASA: 106608461(tkfc)
OMY: 110510458(tkfc)
OGO: 124022895(tkfc)
SNH: 120042750(tkfc)
CCLU: 121571078(tkfc)
ELS: 105007456(tkfc)
SFM: 108924172(tkfc)
AANG: 118232326(tkfc)
LOC: 102690531(tkfc)
PSPA: 121294721(tkfc)
ARUT: 117432065(tkfc)
LCM: 102352724(TKFC)
CMK: 103191379
CIN: 100182010
SCLV: 120337236
SPU: 575781
SKO: 100371401
AAG: 5577462
BCOO: 119078900
AME: 413697
ACER: 107997413
ALAB: 122714572
BBIF: 117213237
BVK: 117239461
BVAN: 117164121
BTER: 100647598
BPYO: 122566187
NMEA: 116431748
CGIG: 122399847
PFUC: 122518485
VPS: 122631458
TPRE: 106656000
SOY: 115885751
CSET: 123316509
AGB: 108916147
LDC: 111511001
APLN: 108741124
PPYR: 116171600
OTU: 111416254
HZE: 124629934
DCI: 103512699
TPAL: 117652890
PJA: 122264892
PCHN: 125038880
HAME: 121860272
PCLA: 123764503
PTRU: 123504284
HAZT: 108676461
EAF: 111713808
LSM: 121117096
DSV: 119464144
RMP: 119164289
VDE: 111247300
VJA: 111268934
DFR: 124497272
CEL: CELE_W02H5.8(W02H5.8)
CBR: CBG_06637
BMY: BM_BM6148(Bm6148)
BGT: 106057946
MYI: 110446463
PMAX: 117324007
MMER: 123530548
OBI: 106884066
OSN: 115217112
NVE: 5520788
ATEN: 116305169
ADF: 107338117
XEN: 124441741
HMG: 101240707
AQU: 100632756
ATH: AT1G48430
ALY: 9330174
CRB: 17900046
CSAT: 104777760
BRP: 103833003
BNA: 106360538
BOE: 106311598
SCE: YFL053W(DAK2) YML070W(DAK1)
ERC: Ecym_1148
KMX: KLMA_50161(DAK1)
NCS: NCAS_0A06130(NCAS0A06130)
NDI: NDAI_0D03110(NDAI0D03110)
TPF: TPHA_0B01670(TPHA0B01670)
TBL: TBLA_0B06340(TBLA0B06340)
TDL: TDEL_0C00180(TDEL0C00180) TDEL_0D00840(TDEL0D00840)
KAF: KAFR_0I00330(KAFR0I00330)
KNG: KNAG_0E04050(KNAG0E04050)
CAL: CAALFM_C109190CA(DAK2)
NCR: NCU03779(dak-1) NCU04400
NTE: NEUTE1DRAFT121216(NEUTE1DRAFT_121216) NEUTE1DRAFT58250(NEUTE1DRAFT_58250)
ANI: AN0034.2
ANG: ANI_1_890124(An14g06500)
ABE: ARB_03384
TVE: TRV_08068
SPO: SPAC22A12.11(dak1) SPAC977.16c(dak2)
SCM: SCHCO_02545094(SCHCODRAFT_02545094) SCHCO_02619084(SCHCODRAFT_02619084)
ABP: AGABI1DRAFT90110(AGABI1DRAFT_90110)
ABV: AGABI2DRAFT222826(AGABI2DRAFT_222826)
WSE: WALSEDRAFT_53995(DAK-1)
MGL: MGL_0770
MRT: MRET_0047
ENC: ECL_04599
ECLX: LI66_20150
ECLY: LI62_22130
ECLZ: LI64_19250
ECLO: ENC_34560
EEC: EcWSU1_04023(dhaK)
ECAN: CWI88_02350(dhaK)
EBG: FAI37_09195(dhaK)
ESA: ESA_03459
CSK: ES15_3420
CTU: CTU_05070(dhaK)
KPN: KPN_03498(dhaK)
KPU: KP1_4795
KPP: A79E_0619
KPT: VK055_3970(dhaK2)
KPR: KPR_4702(dhaK)
KPJ: N559_0676
KPX: PMK1_01016(dhaK_2)
KPNU: LI86_03265
KPNK: BN49_0609(dhaK1)
KVA: Kvar_0602
KPE: KPK_0615
KOE: A225_5089
EAE: EAE_03865
EAR: CCG33219
KQV: B8P98_03305(dhaK)
KLW: DA718_03815(dhaK)
RAO: DSD31_03350(dhaK)
RTG: NCTC13098_00821(dhaK_1)
CKO: CKO_04479
CBRA: A6J81_20520(dhaK)
CWE: CO701_01105(dhaK)
CYO: CD187_03180(dhaK)
CFQ: C2U38_22240(dhaK)
CAMA: F384_24715
CIF: AL515_20275(dhaK)
CIR: C2U53_02020(dhaK)
CIE: AN232_07845(dhaK)
CPAR: CUC49_16000(dhaK)
CITZ: E4Z61_20185(dhaK)
CARS: E1B03_22845(dhaK)
PSGC: G163CM_30210(dhaK)
EBU: CUC76_18815(dhaK)
VSR: Vspart_03226(dhaK)
ALJ: G8D99_11620(dhaK)
AWG: GFH30_03655(dhaK)
ASHA: G8E00_04420(dhaK)
AVB: RYU24_22380(dhaL)
ORB: IPMB12_01255(dhaK)
BMA: BMA1001(dak)
BMAL: DM55_2874(dak)
BMAE: DM78_1552(dak)
BMAQ: DM76_2858(dak)
BMAI: DM57_196
BMAF: DM51_754
BPS: BPSL1613
BPM: BURPS1710b_2248(dak)
BPSE: BDL_159(dak)
BPSM: BBQ_1492(dak)
BPSU: BBN_1618(dak)
BPSD: BBX_2095(dak)
BPK: BBK_3113(dak)
BPSH: DR55_2728(dak)
BPSA: BBU_309(dak)
BPSO: X996_2322(dak)
BUT: X994_748
BTE: BTH_I2329
BTQ: BTQ_1589(dak)
BTJ: BTJ_767(dak)
BTZ: BTL_2004(dak)
BTD: BTI_1824(dak)
BTV: BTHA_2160(dak)
BTHE: BTN_2757(dak)
BTHM: BTRA_2288(dak)
BTHA: DR62_2907
BTHL: BG87_2230
BHG: I6G56_11385(dhaK)
BVE: AK36_6051
BCJ: BCAS0051
BCEN: DM39_6662(dak)
BCEO: I35_7048
BAM: Bamb_6032
BMJ: BMULJ_05394(dak1)
BMU: Bmul_6137
BMK: DM80_6591
BMUL: NP80_5344
BCED: DM42_6421(dhaL)
BCON: NL30_33765
BUB: BW23_3201
BTEI: WS51_29650
BSEM: WJ12_19000
BPSL: WS57_18455
BMEC: WJ16_19785
BSTG: WT74_09370
BGU: KS03_1640(dhaL)
BGO: BM43_2153(dhaL)
BUK: MYA_5072
BUL: BW21_1933(dAK)
BGP: BGL_1c07050(dhaK)
BXE: Bxe_B2559
BXB: DR64_4885(dhaK)
BFN: OI25_5137(dhaL)
PSPW: BJG93_20355(dhaK)
PMEG: FNZ07_17610(dhaK)
PTRO: G5S35_21515(dhaK)
PGIS: I6I06_18185(dhaK)
PACP: FAZ97_29805(dhaK)
PACS: FAZ98_23800(dhaK)
CABA: SBC2_34100
DAC: Daci_4585
DLA: I6G47_01530(dhaL)
MLO: mll5296
MHUA: MCHK_6340
SMD: Smed_4228
SFD: USDA257_c27550(dhaK3)
ATU: Atu3543(dhbK)
AGC: BSY240_25
RET: RHE_CH02988(dak)
REC: RHECIAT_CH0002635(dhaK)
RLE: RL2900(dhaK1)
RLG: Rleg_2432
RHL: LPU83_pLPU83c0203(dhaK3)
SHZ: shn_26435
KAI: K32_07190(dhbK)
AZC: AZC_4706
SNO: Snov_4106
MEA: Mex_1p0796(dhaK)
MDI: METDI1510(dhaK)
MEX: Mext_1031
MCH: Mchl_1158
MPO: Mpop_0963
MET: M446_3559
MOR: MOC_3256
MIND: mvi_14850
PLIA: E4191_10540(dhaL)
KRE: GWK63_14835(dhaL)
BANV: DJ46_5425(dhaK2) DJ46_5427(dhaK)
BCZ: BCE33L0870(dhaL)
BCQ: BCQ_1042 BCQ_1044(dhaL)
BCX: BCA_1007
BAL: BACI_c10030(dhaL2)
BCF: bcf_04880
BCER: BCK_03405
BTK: BT9727_0887(dhaL) BT9727_0889(dhaL)
BTL: BALH_0872
BTT: HD73_1125
BTHI: BTK_05660
BTM: MC28_0219
BTG: BTB_c10280(dhaK2)
BTI: BTG_16090
BTW: BF38_2210(dhaK2) BF38_2212(dhaK)
BWW: bwei_4034(dhaK2)
BMYO: BG05_4930(dhaK)
BMYC: DJ92_3631(dhaK)
BTRO: FJR70_26950(dhaQ) FJR70_26965(dhaK)
BNT: GSN03_05220(dhaK)
PKS: IE339_07290(dhaK)
BHA: BH3393
TAID: KS242_05045(dhaK)
BVQ: FHE72_04315(dhaK)
RMF: D5E69_04665(dhaK)
PBAC: HUB98_21675(dhaK)
LLM: llmg_0255(dhaK)
LLC: LACR_0250
LLW: kw2_0237
LPL: lp_0166(dak1A)
LPJ: JDM1_0155(dak1A)
LPT: zj316_0370(dak1A)
LPS: LPST_C0134(dak1A)
LPZ: Lp16_0150
LARG: LPA65_00740(dhaQ)
VFV: K5K99_04840(dhaQ)
VLU: M2919_08440(dhaQ)
CPE: CPE0100
CPF: CPF_0095
CBO: CBO0975(dhaK)
CBA: CLB_1015(dhaKL)
CBH: CLC_1029(dhaKL)
CBY: CLM_1131(dhaKL)
CBL: CLK_0423(dhaKL)
CBK: CLL_A0538(dhaKL)
CBB: CLD_3590(dhaKL)
CBI: CLJ_B1020(dhaKL)
CBF: CLI_1061(dhaKL)
CBM: CBF_1031(dhaKL)
CPAT: CLPA_c12160(dhaK)
CPAE: CPAST_c12160(dhaK)
CLD: CLSPO_c09760(dhaK)
CDY: F3K33_19840(dhaK)
CGAS: J1C67_12320(dhaK)
PBIF: KXZ80_02440(dhaK)
ACEL: acsn021_24320(dhaK)
TEM: JW646_17505(dhaK)
TGC: L0P85_10560(dhaK)
MAUU: NCTC10437_05243(dhaK_2)
MAB: MAB_0194
MABB: MASS_0192
CEE: CENDO_00155(dhaK)
CPRE: Csp1_09020(dhaK)
COK: COCCU_04595(dhaK)
RER: RER_56200(dak)
REY: O5Y_26840
ROP: ROP_15290(dak)
RKO: JWS14_09475(dhaL)
GBR: Gbro_4101
TPR: Tpau_0779
YIA: LO772_07750(dhaL)
CMS: CMS2383
SAIU: J4H86_13525(dhaL)
KRA: Krad_4000
AMI: Amir_2647
CAI: Caci_1105
SNA: Snas_4072
AHE: Arch_1123
ARCA: HC352_05770(dhaK)
APHO: JTE88_05725(dhaK)
APII: NG665_05665(dhaK)
TTR: Tter_2484
ADIN: H7849_16125(dhaK)
CPI: Cpin_4584
 » show all
Reference
  Authors
Rodrigues JR, Couto A, Cabezas A, Pinto RM, Ribeiro JM, Canales J, Costas MJ, Cameselle JC
  Title
Bifunctional homodimeric triokinase/FMN cyclase: contribution of protein domains to the activities of the human enzyme and molecular dynamics simulation of domain movements.
  Journal
J Biol Chem 289:10620-36 (2014)
DOI:10.1074/jbc.M113.525626
  Sequence
[hsa:26007]
Reference
  Authors
Cabezas A, Costas MJ, Pinto RM, Couto A, Cameselle JC
  Title
Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases.
  Journal
Biochem Biophys Res Commun 338:1682-9 (2005)
DOI:10.1016/j.bbrc.2005.10.142
  Sequence
[hsa:26007] [rno:361730]

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