KEGG   ORTHOLOGY: K01027
Entry
K01027                      KO                                     

Name
OXCT
Definition
3-oxoacid CoA-transferase [EC:2.8.3.5]
Pathway
ko00072  Synthesis and degradation of ketone bodies
ko00280  Valine, leucine and isoleucine degradation
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
Disease
H01121  Succinyl CoA:3-oxoacid CoA transferase (SCOT) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    K01027  OXCT; 3-oxoacid CoA-transferase
  09103 Lipid metabolism
   00072 Synthesis and degradation of ketone bodies
    K01027  OXCT; 3-oxoacid CoA-transferase
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K01027  OXCT; 3-oxoacid CoA-transferase
Enzymes [BR:ko01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.3  CoA-transferases
    2.8.3.5  3-oxoacid CoA-transferase
     K01027  OXCT; 3-oxoacid CoA-transferase
Other DBs
RN: R00410
GO: 0008260
Genes
HSA: 5019(OXCT1) 64064(OXCT2)
PTR: 112209812 456780(OXCT2) 737468(OXCT1)
PPS: 100978986(OXCT1) 100994494(OXCT2)
GGO: 101149385(OXCT1) 101149656(OXCT2) 115930581
PON: 100173667(OXCT1) 100443574(OXCT2) 100447637
NLE: 100606587(OXCT2) 100606944(OXCT1) 115837500
MCC: 106995511(OXCT2) 106997886 696642(OXCT1)
MCF: 101866052(OXCT1) 102131318(OXCT2) 102137293
CSAB: 103215192(OXCT1) 103225047 103225058
RRO: 104654878 104660749(OXCT1)
RBB: 108517058(OXCT2) 108526488(OXCT1) 108535565
CJC: 100414476(OXCT1)
SBQ: 101040167(OXCT2) 101054248(OXCT1)
MMU: 353371(Oxct2b) 64059(Oxct2a) 67041(Oxct1)
MCAL: 110292194(Oxct2) 110310194(Oxct1)
MPAH: 110322868(Oxct2) 110328779(Oxct1)
RNO: 100361036 366463(Oxct2a) 690163(Oxct1)
MUN: 110549954(Oxct2) 110563144(Oxct1)
NGI: 103741342(Oxct1)
HGL: 101716155(Oxct2) 101718900(Oxct1)
TUP: 102476335(OXCT1)
CFA: 479347(OXCT1)
VVP: 112933510(OXCT1)
AML: 100466284(OXCT1) 109488478
UMR: 103664669(OXCT1)
UAH: 113260937(OXCT1)
ORO: 101370149(OXCT1)
ELK: 111141198
FCA: 100151771(OXCT1) 101088562 111561711(OXCT2)
PTG: 102967466(OXCT1)
AJU: 106970881(OXCT1) 106988987
BTA: 100297708 535804(OXCT1) 782973(OXCT2)
BBUB: 102410048(OXCT1) 112585707(OXCT2) 112585709
OAS: 101102177(OXCT1) 105604051 105605147(OXCT2)
SSC: 396978(OXCT1)
CFR: 102511684(OXCT1) 102513512
CDK: 105106646 105106980(OXCT1)
LVE: 103070147(OXCT1) 103088008(OXCT2)
OOR: 101285661(OXCT1) 105747834(OXCT2)
DLE: 111175625 111175634(OXCT2) 111187102(OXCT1)
ECB: 100054330(OXCT2) 100065846(OXCT1)
EPZ: 103551240(OXCT2) 103563602(OXCT1)
EAI: 106830581(OXCT2) 106847869(OXCT1)
MYB: 102242060(OXCT2) 102254906(OXCT1)
MYD: 102764594(OXCT1)
MNA: 107541799(OXCT2) 107545848(OXCT1)
HAI: 109374584(OXCT1) 109390922(OXCT2)
DRO: 112299185(OXCT2) 112320986(OXCT1)
PALE: 102888023(OXCT1)
RAY: 107505376
MJV: 108401088(OXCT1)
LAV: 100669554(OXCT1) 104846362 104846363(OXCT2)
MDO: 100018163(OXCT1)
SHR: 100930489(OXCT1)
PCW: 110215140(OXCT1)
OAA: 100075056(OXCT1)
GGA: 427190(OXCT1)
MGP: 100546776(OXCT1)
CJO: 107305960(OXCT1)
NMEL: 110389309(OXCT1)
APLA: 101800861(OXCT1)
ACYG: 106036290(OXCT1)
TGU: 100226133(OXCT1)
LSR: 110482275(OXCT1)
SCAN: 103821020(OXCT1)
GFR: 102039545(OXCT1)
FAB: 101809432(OXCT1)
PHI: 102110719(OXCT1)
PMAJ: 107216113(OXCT1)
CCAE: 111941377(OXCT1)
CCW: 104686630(OXCT1)
ETL: 114063715(OXCT1)
FPG: 101924576(OXCT1)
FCH: 102054890(OXCT1)
CLV: 102089756(OXCT1)
EGZ: 104133933(OXCT1)
NNI: 104016191(OXCT1)
ACUN: 113489790(OXCT1)
PADL: 103917444(OXCT1)
AAM: 106499547(OXCT1)
ASN: 102386191
AMJ: 102564628(OXCT1)
PSS: 102461214(OXCT1)
CMY: 102942043
CPIC: 101945142(OXCT1)
ACS: 100566475(oxct1)
PVT: 110073911(OXCT1)
PBI: 103052512(OXCT1)
PMUR: 107295926(OXCT1)
TSR: 106548001(OXCT1) 106552331
PMUA: 114606149(OXCT1)
GJA: 107121555(OXCT1)
XLA: 108707302(oxct1.S) 398820(oxct1.L)
XTR: 493307(oxct1)
NPR: 108796898(OXCT1)
DRE: 442923(oxct1a) 560273(oxct1b) 797311
IPU: 108265146(oxct1)
TRU: 101072066(oxct1)
LCO: 104920658(oxct1)
NCC: 104943316(oxct1)
MZE: 101466319(oxct1)
ONL: 100706017(oxct1)
OLA: 101163581(oxct1)
XMA: 102230613(oxct1)
XCO: 114154899(oxct1)
PRET: 103470144(oxct1)
CVG: 107093854(oxct1)
NFU: 107394099(oxct1)
KMR: 108244812(oxct1)
ALIM: 106513714(oxct1)
AOCE: 111575657(oxct1)
CSEM: 103397683(oxct1)
POV: 109639326(oxct1)
LCF: 108882574(oxct1)
SDU: 111230819(oxct1)
SLAL: 111645119(oxct1)
HCQ: 109517516(oxct1)
BPEC: 110167014(oxct1)
MALB: 109956556(oxct1)
ELS: 105023334(oxct1)
LCM: 102362347(OXCT1)
RTP: 109927370
CIN: 100180566
APLC: 110989387
SKO: 100374114
DME: Dmel_CG1140(SCOT)
DER: 6546453
DSE: 6610434
DSI: Dsimw501_GD13661(Dsim_GD13661)
DAN: 6507479
DSR: 110188888
DPE: 6599089
DMN: 108151741
DWI: 6645023
DAZ: 108613468
DNV: 108650901
DHE: 111603051
DVI: 6624252
MDE: 101888363
AAG: 5574420
AME: 409157
BIM: 100740039
BTER: 100646203
CCAL: 108624937
OBB: 114876706
SOC: 105197413
MPHA: 105828252
AEC: 105148278
ACEP: 105624454
PBAR: 105429280
VEM: 105561199
HST: 105189097
DQU: 106747987
CFO: 105247948
LHU: 105675171
PGC: 109861269
OBO: 105284354
PCF: 106788260
NVI: 100122534
CSOL: 105363248
TCA: 657047
DPA: 109546251
ATD: 109609608
BMOR: 101737459
BMAN: 114250847
PMAC: 106714796
PRAP: 110998493
HAW: 110378988
TNL: 113502260
API: 100159806
DNX: 107168031
AGS: 114123454
RMD: 113551656
BTAB: 109035025
CLEC: 106667319
ZNE: 110829277
FCD: 110859903
PVM: 113815045
DPTE: 113794051
PTEP: 107443751
CEL: CELE_C05C10.3(C05C10.3)
CBR: CBG00970
TSP: Tsp_11447
CRG: 105334265
MYI: 110459125
OBI: 106877113
LAK: 106158549
NVE: 5519063
EPA: 110236818
ADF: 107335238
AMIL: 114952906
PDAM: 113684195
SPIS: 111326804
DGT: 114524141
HMG: 100199253(oxct1) 100209501
PIC: PICST_33142(OCA3)
CAL: CAALFM_C207240CA(CaO19.2281)
NTE: NEUTE1DRAFT66517(NEUTE1DRAFT_66517) NEUTE1DRAFT86496(NEUTE1DRAFT_86496)
MGR: MGG_11480
MBE: MBM_06774
ANG: ANI_1_164054(An06g01370) ANI_1_30014(An01g00200) ANI_1_378014(An01g03000)
ABE: ARB_03474
TVE: TRV_06128
CNE: CNL05860
CNB: CNBI0970
ABP: AGABI1DRAFT98001(AGABI1DRAFT_98001)
ABV: AGABI2DRAFT134289(AGABI2DRAFT_134289)
MGL: MGL_0383
MRT: MRET_2205
DDI: DDB_G0288105(oxct)
DFA: DFA_09259(oxct)
SMIN: v1.2.025547.t1(symbB.v1.2.025547.t1)
PTI: PHATRDRAFT_23365(SKT1)
TPS: THAPSDRAFT_31777(OCT1)
SPAR: SPRG_10775
AHN: NCTC12129_01590(atoA)
DKO: I596_3037
RBD: ALSL_2161
PFE: PSF113_3470(scoB)
ADI: B5T_00044
DAR: Daro_1021
AZA: AZKH_0569(oxcT)
DEU: DBW_3522(scoA)
AVI: Avi_7413
STAX: MC45_16510
BMQ: BMQ_2370(scoB)
BMD: BMD_2332(scoB)
BMH: BMWSH_2864(atoA)
BMEG: BG04_4743
MPA: MAP_3861(scoB)
MAO: MAP4_3976
MAVI: RC58_19745
MAVU: RE97_19800
MAV: MAV_4786
MIT: OCO_46970
MIA: OCU_46700
MID: MIP_07106
MYO: OEM_47080
MIR: OCQ_47990
MLP: MLM_3949
MMM: W7S_23570
CEF: CE0326
CMV: CMUST_12010(Oxct1)
CAQU: CAQU_03665
PDX: Psed_3035
DRA: DR_A0054
DGE: Dgeo_1306
DGO: DGo_CA0566(scoB)
DFC: DFI_06220
MRB: Mrub_2696
SLI: Slin_1533
PSEZ: HME7025_01871(oxcT)
MARM: YQ22_04995
 » show all
Reference
PMID:8751852
  Authors
Kassovska-Bratinova S, Fukao T, Song XQ, Duncan AM, Chen HS, Robert MF, Perez-Cerda C, Ugarte M, Chartrand C, Vobecky S, Kondo N, Mitchell GA
  Title
Succinyl CoA: 3-oxoacid CoA transferase (SCOT): human cDNA cloning, human chromosomal mapping to 5p13, and mutation detection in a SCOT-deficient patient.
  Journal
Am J Hum Genet 59:519-28 (1996)
Reference
  Authors
Bateman KS, Brownie ER, Wolodko WT, Fraser ME
  Title
Structure of the mammalian CoA transferase from pig heart.
  Journal
Biochemistry 41:14455-62 (2002)
DOI:10.1021/bi020568f
Reference
  Authors
Tanaka H, Kohroki J, Iguchi N, Onishi M, Nishimune Y
  Title
Cloning and characterization of a human orthologue of testis-specific succinyl CoA: 3-oxo acid CoA transferase (Scot-t) cDNA.
  Journal
Mol Hum Reprod 8:16-23 (2002)
DOI:10.1093/molehr/8.1.16
  Sequence
[hsa:64064]
Reference
  Authors
Onishi M, Yasunaga T, Tanaka H, Nishimune Y, Nozaki M
  Title
Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b.
  Journal
Genomics 83:647-57 (2004)
DOI:10.1016/j.ygeno.2003.09.018

DBGET integrated database retrieval system