KEGG   ORTHOLOGY: K01059Help
Entry
K01059                      KO                                     

Name
LPL
Definition
lipoprotein lipase [EC:3.1.1.34]
Pathway
ko00561  Glycerolipid metabolism
ko01100  Metabolic pathways
ko03320  PPAR signaling pathway
ko04979  Cholesterol metabolism
ko05010  Alzheimer's disease
Disease
H00154  Hyperlipoproteinemia, type I
H01635  Hyperlipidemia
H01637  Hypertriglyceridemia
H01784  Primary hyperchylomicronemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00561 Glycerolipid metabolism
    K01059  LPL; lipoprotein lipase
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    K01059  LPL; lipoprotein lipase
  Digestive system
   04979 Cholesterol metabolism
    K01059  LPL; lipoprotein lipase
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K01059  LPL; lipoprotein lipase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.34  lipoprotein lipase
     K01059  LPL; lipoprotein lipase
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of microglial cells
   K01059  LPL; lipoprotein lipase
  Exosomal proteins of breast milk
   K01059  LPL; lipoprotein lipase
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Enzymes
   K01059  LPL; lipoprotein lipase
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
 Enzymes
  K01059  LPL; lipoprotein lipase
BRITE hierarchy
Other DBs
RN: R01350
GO: 0004465
Genes
HSA: 4023(LPL)
PTR: 464031(LPL)
PPS: 100986925(LPL)
GGO: 101124245(LPL)
PON: 100443394(LPL)
NLE: 100584438(LPL)
MCC: 712887(LPL)
MCF: 102129758(LPL)
CSAB: 103215415(LPL)
RRO: 104662456(LPL)
RBB: 108526485(LPL)
CJC: 100409187(LPL)
SBQ: 101050033(LPL)
MMU: 16956(Lpl)
RNO: 24539(Lpl)
CGE: 100689191(Lpl)
NGI: 103747648(Lpl)
HGL: 101703016(Lpl)
CCAN: 109695316 109695324(Lpl)
OCU: 100340171(LPL)
TUP: 102492328(LPL)
CFA: 403626(LPL)
AML: 100482804(LPL)
UMR: 103676703(LPL)
ORO: 101380450(LPL)
FCA: 727696(LPL)
PTG: 102967736(LPL)
AJU: 106971857(LPL)
BTA: 280843(LPL)
BOM: 102266770(LPL)
BIU: 109563092(LPL)
PHD: 102341297(LPL)
CHX: 100860750(LPL)
OAS: 443408(LPL)
SSC: 397537(LPL)
CFR: 102520179(LPL)
CDK: 105094532(LPL)
BACU: 103005101
LVE: 103083746(LPL)
OOR: 101284828(LPL)
ECB: 100055358(LPL)
EPZ: 103559571(LPL)
EAI: 106831205(LPL)
MYB: 102247387(LPL)
MYD: 102759852(LPL)
HAI: 109382488(LPL)
RSS: 109450058(LPL)
PALE: 102892638(LPL)
LAV: 100667686(LPL)
TMU: 101345905
MDO: 100033067(LPL)
SHR: 100933361(LPL)
OAA: 100077350(LPL)
GGA: 396219(LPL)
MGP: 100544844(LPL)
CJO: 107306443(LPL)
APLA: 101796218(LPL)
ACYG: 106040417(LPL)
TGU: 100223817(LPL)
GFR: 102041807(LPL)
FAB: 101814126(LPL)
PHI: 102111905(LPL)
PMAJ: 107216453(LPL)
CCW: 104689737(LPL)
FPG: 101913413(LPL)
FCH: 102046454(LPL)
CLV: 102097018(LPL)
EGZ: 104123360(LPL)
ASN: 102368909(LPL)
AMJ: 102573889(LPL)
PSS: 102456906(LPL)
CMY: 102941095
CPIC: 101932991(LPL)
ACS: 100556298(lpl)
PVT: 110083190(LPL)
PBI: 103057093(LPL)
GJA: 107118995(LPL)
XLA: 108706825(lpl.S) 108712233(lpl.L)
XTR: 100127862(lpl)
NPR: 108804916(LPL)
IPU: 108271131(LPL) 108280930
TRU: 101062428(lpl) 101068642(LPL2)
OLA: 101160309(lpl) 101160547
PRET: 103463532 103463534(lpl)
NFU: 107393172 107393174(lpl)
CSEM: 103397050 103397060(lpl)
LCF: 108881396 108881397(lpl)
BPEC: 110160148
SFM: 108919920 108919924(lpl)
LCM: 102349247(LPL) 102362907
CMK: 103183498(lpl) 103183499
PMAC: 106717696
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lutz EP, Merkel M, Kako Y, Melford K, Radner H, Breslow JL, Bensadoun A, Goldberg IJ
  Title
Heparin-binding defective lipoprotein lipase is unstable and causes abnormalities in lipid delivery to tissues.
  Journal
J Clin Invest 107:1183-92 (2001)
DOI:10.1172/JCI11774
  Sequence
[hsa:4023]
Reference
  Authors
Gin P, Beigneux AP, Davies B, Young MF, Ryan RO, Bensadoun A, Fong LG, Young SG
  Title
Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution.
  Journal
Biochim Biophys Acta 1771:1464-8 (2007)
DOI:10.1016/j.bbalip.2007.10.005

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