KEGG ORTHOLOGY: K01106

ORTHOLOGY: K01106

Entry

K01106                      KO

Symbol

INPP5A

Name

inositol polyphosphate 5-phosphatase INPP5A [EC:3.1.3.56]

Pathway

map00562

Inositol phosphate metabolism

map01100

Metabolic pathways

map04070

Phosphatidylinositol signaling system

map04910

Insulin signaling pathway

Module

M00131

Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol

Reaction

R03394

D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase

R03430

D-myo-inositol 1,3,4,5-tetrakisphosphate 5-phosphohydrolase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K01106  INPP5A; inositol polyphosphate 5-phosphatase INPP5A
09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    K01106  INPP5A; inositol polyphosphate 5-phosphatase INPP5A
09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K01106  INPP5A; inositol polyphosphate 5-phosphatase INPP5A
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.56  inositol-polyphosphate 5-phosphatase
     K01106  INPP5A; inositol polyphosphate 5-phosphatase INPP5A

Other DBs

GO:

0004445

Genes

HSA:	3632(INPP5A)

PTR:	747128(INPP5A)

PPS:	100995871(INPP5A)

GGO:	101137047(INPP5A)

PON:	100440857(INPP5A)

PPYG:

129045328(INPP5A)

NLE:	100587560(INPP5A)

HMH:	116478297(INPP5A)

SSYN:

129464093(INPP5A)

MCC:	719508(INPP5A)

MCF:	102124549(INPP5A)

MTHB:

126963300

MNI:	105471065(INPP5A)

CSAB:

103216744(INPP5A)

CATY:

105599001(INPP5A)

PANU:

101015151(INPP5A)

TGE:	112631998(INPP5A)

MLEU:

105540285(INPP5A)

RRO:	104677635(INPP5A)

RBB:	108543386(INPP5A)

TFN:	117082515(INPP5A)

PTEH:

111522049(INPP5A)

CANG:

105511780(INPP5A)

CJC:	100387531(INPP5A)

SBQ:	101037105(INPP5A)

CIMI:

108292591(INPP5A)

ANAN:

105734611(INPP5A)

CSYR:

103262593(INPP5A)

MMUR:

105866235 109729444

LCAT:

123650405(INPP5A)

PCOQ:

105823468(INPP5A)

OGA:	100941367(INPP5A)

MMU:	212111(Inpp5a)

MCAL:

110298346(Inpp5a)

MPAH:

110320177(Inpp5a)

RNO:	365382(Inpp5a)

MCOC:

116103158(Inpp5a)

ANU:	117715712(Inpp5a)

MUN:	110549016(Inpp5a)

CGE:	100760037(Inpp5a)

MAUA:

101830376(Inpp5a)

PROB:

127228490(Inpp5a)

PLEU:

114693188(Inpp5a)

MORG:

121457556(Inpp5a)

MFOT:

126498387

AAMP:

119817202(Inpp5a)

NGI:	103725829(Inpp5a)

HGL:	101704617(Inpp5a)

CPOC:

100729042(Inpp5a)

CCAN:

109698635(Inpp5a)

DORD:

105989698(Inpp5a)

DSP:	122101837(Inpp5a)

PLOP:

125345932(Inpp5a)

NCAR:

124985368

MMMA:

107152934(Inpp5a)

OCU:

103347071

OPI:	101535675(INPP5A)

TUP:	102485414(INPP5A)

GVR:

103599063

CFA:	403937(INPP5A)

CLUD:

112672530(INPP5A)

VVP:	112928852(INPP5A)

VLG:	121484412(INPP5A)

NPO:	129523404(INPP5A)

AML:	100465896(INPP5A)

UMR:	103658509(INPP5A)

UAH:	113252083(INPP5A)

UAR:	123800028(INPP5A)

ELK:

111145269

LLV:

125084898

MPUF:

101677938(INPP5A)

MNP:	132016895(INPP5A)

MLK:	131830513(INPP5A)

NVS:	122901232(INPP5A)

ORO:	101368492(INPP5A)

EJU:	114221763(INPP5A)

ZCA:	113920906(INPP5A)

MLX:	117997970(INPP5A)

NSU:	110592750(INPP5A)

LWW:	102728965(INPP5A)

FCA:	101083037(INPP5A)

PYU:	121037491(INPP5A)

PCOO:

112854729(INPP5A)

PBG:	122493403(INPP5A)

PVIV:

125147873(INPP5A)

LRUF:

124507244

PTG:	102951654(INPP5A)

PPAD:

109256690(INPP5A)

PUC:

125933063

AJU:

113600366

HHV:	120245366(INPP5A)

BTA:	615232(INPP5A)

BOM:	102285484(INPP5A)

BIU:	109579046(INPP5A)

BBUB:

102402973(INPP5A)

BBIS:

105002740(INPP5A)

CHX:	102181924(INPP5A)

OAS:	101110014(INPP5A)

BTAX:

128067664(INPP5A)

ODA:	120873937(INPP5A)

CCAD:

122445810(INPP5A)

MBEZ:

129555233(INPP5A)

SSC:	100512501(INPP5A)

CFR:	102510594(INPP5A)

CBAI:

105067057(INPP5A)

CDK:	105104581(INPP5A)

VPC:	102536179(INPP5A)

BACU:

103018455(INPP5A)

BMUS:

118882765(INPP5A)

LVE:	103088886(INPP5A)

OOR:	101278141(INPP5A)

DLE:	111172172(INPP5A)

PCAD:

102996894(INPP5A)

PSIU:

116741224(INPP5A)

NASI:

112411270(INPP5A)

ECB:	100051027(INPP5A)

EPZ:	103554530(INPP5A)

EAI:	106841072(INPP5A)

MYB:	102256550(INPP5A)

MYD:	102770814(INPP5A)

MMYO:

118669660(INPP5A)

MLF:	102423116(INPP5A)

MDT:	132214425(INPP5A)

PKL:	118719566(INPP5A)

EFUS:

103288618(INPP5A)

MNA:	107532111(INPP5A)

DRO:	112300235(INPP5A)

SHON:

118990578(INPP5A)

AJM:	119059475(INPP5A)

PDIC:

114496465(INPP5A)

PHAS:

123828723(INPP5A)

MMF:	118632061(INPP5A)

PPAM:

129079701(INPP5A)

HAI:	109383559(INPP5A)

RFQ:	117035931(INPP5A)

PALE:

102886411(INPP5A)

PGIG:

120581223(INPP5A)

PVP:	105300399(INPP5A)

RAY:	107517147(INPP5A)

MJV:	108396822(INPP5A)

TOD:	119233487(INPP5A)

SARA:

101544032(INPP5A)

SETR:

126033645(INPP5A)

LAV:	100655016(INPP5A)

TMU:

101345194

ETF:	101659815(INPP5A)

DNM:	101417604(INPP5A)

MDO:	107650382(INPP5A)

GAS:	123234402(INPP5A)

AFZ:

127552229

PCW:	110198691(INPP5A)

TVP:	118830052(INPP5A)

OAA:	100093027(INPP5A)

GGA:	423973(INPP5A)

PCOC:

116231509(INPP5A)

MGP:

100548603

CJO:	107316265(INPP5A)

TPAI:

128077595(INPP5A)

LMUT:

125692874(INPP5A)

NMEL:

110399478(INPP5A)

APLA:

101804204(INPP5A)

ACYG:

106047331(INPP5A)

CATA:

118248541(INPP5A)

AFUL:

116491245(INPP5A)

TGU:	100218210(INPP5A)

LSR:	110477043(INPP5A)

SCAN:

103814084(INPP5A)

PMOA:

120512738(INPP5A)

OTC:	121333629(INPP5A)

PRUF:

121353476(INPP5A)

GFR:	102036109(INPP5A)

FAB:	101814745(INPP5A)

OMA:	130254898(INPP5A)

PHI:	102099529(INPP5A)

PMAJ:

107206908(INPP5A)

CCAE:

111931657(INPP5A)

CCW:	104694952(INPP5A)

CBRC:

103615323(INPP5A)

ETL:	114067417(INPP5A)

ZAB:	102066323(INPP5A)

ZLE:	135449620(INPP5A)

SVG:	106861935(INPP5A)

MMEA:

130584245(INPP5A)

HRT:	120755763(INPP5A)

SATI:

136363928(INPP5A)

FPG:	101924782(INPP5A)

FCH:	102054445(INPP5A)

SHAB:

115608073(INPP5A)

ACUN:

113481514(INPP5A)

TALA:

104360248(INPP5A)

ACHC:

115348316(INPP5A)

HLE:	104840790(INPP5A)

AGEN:

126043240

GCL:

127017717

DPUB:

104305699(INPP5A)

BRHI:

104498963(INPP5A)

EGZ:	104128277(INPP5A)

NNI:	104013867(INPP5A)

PCAO:

104042502(INPP5A)

PADL:

103918623(INPP5A)

AFOR:

103897957(INPP5A)

CLV:	102090809(INPP5A)

MUI:	104538543(INPP5A)

CUCA:

104063108(INPP5A)

OHA:	104326835(INPP5A)

ACAR:

104521172(INPP5A)

CPEA:

104388659(INPP5A)

CVF:	104293246(INPP5A)

RTD:	128910781(INPP5A)

AAM:	106485811(INPP5A)

AROW:

112966030(INPP5A)

NPD:	112944713(INPP5A)

TGT:	104574359(INPP5A)

DNE:	112992662(INPP5A)

SCAM:

104141318(INPP5A)

ASN:

102368100

AMJ:	102559502(INPP5A)

CPOO:

109324062(INPP5A)

GGN:	109287734(INPP5A)

PSS:	102447470(INPP5A)

CMY:	102929515(INPP5A)

CCAY:

125639744(INPP5A)

DCC:	119858503(INPP5A)

CPIC:

101940311(INPP5A)

TST:	117879808(INPP5A)

CABI:

116836222(INPP5A)

MRV:	120368611(INPP5A)

ACS:	100552188(inpp5a)

ASAO:

132771069(INPP5A)

PVT:	110079716(INPP5A)

SUND:

121925149(INPP5A)

PBI:	103066208(INPP5A)

CTIG:

120305502(INPP5A)

TSR:	106548666(INPP5A)

PGUT:

117676750(INPP5A)

APRI:

131200477(INPP5A)

PTEX:

113442748(INPP5A)

NSS:	113414033(INPP5A)

VKO:	123018516(INPP5A)

PMUA:

114597360(INPP5A)

PRAF:

128414095(INPP5A)

ZVI:	118096261(INPP5A)

HCG:	128350161(INPP5A)

GJA:	107123620(INPP5A)

STOW:

125437730(INPP5A)

EMC:	129332305(INPP5A)

XLA:	108696106(inpp5a.1.L) 447532(inpp5a.1.S)

XTR:	548959(inpp5a.1)

NPR:	108784796(INPP5A)

RTEM:

120946720(INPP5A)

BBUF:

121006100(INPP5A)

BGAR:

122940339(INPP5A)

MUO:	115470088(INPP5A)

GSH:	117359397(INPP5A)

DRE:	101884388 101884438 641571(inpp5l)

SRX:	107723704 107740985 107744939 107754011(inpp5a)

SANH:

107683877 107689356(inpp5a) 107702838

SGH:	107548265 107565107 107571644(inpp5a)

CCAR:

109085962

CAUA:

113056594 113070714 113112317

CGIB:

127969953 128018351 128025831

PTET:

122350436(inpp5l) 122356328

LROH:

127169589(inpp5l) 127175366

OMC:	131545354(inpp5l) 131551795

PPRM:

120460866 120486629(inpp5l)

RKG:	130081954(inpp5l)

MAMB:

125276508 125279486(inpp5l)

CIDE:

127517548 127525421

CERY:

137020326(inpp5a) 137027278(inpp5l)

MASI:

127411960 127414381 127414692 127424312

TROS:

130558786 130568213(inpp5l)

TDW:	130431921 130439775(inpp5l)

MANU:

129414030(inpp5l) 129415910

IPU:	108263413 108265505(inpp5l)

IFU:	128605857 128607503(inpp5l)

PHYP:

113533278 113540195(inpp5a)

SMEO:

124399593 124400271(inpp5l)

TFD:	113656046(inpp5l) 113660971

TVC:	132847458 132853758(inpp5l)

TRN:	134314261 134318395(inpp5l)

AMEX:

103024601(inpp5l) 103037390

CMAO:

118810646 118813311(inpp5l)

EEE:	113584197(inpp5a) 113586700

CHAR:

105894892(inpp5l)

TRU:	101070549 101075361(inpp5a)

TFS:	130525291(inpp5l) 130534046

TNG:	GSTEN00011931G001 GSTEN00031711G001

LCO:	104925786(inpp5a) 104935318

NCC:

104961210

TBEN:

117475901 117496888(inpp5l)

CGOB:

115013152 115019877(inpp5a)

PGEO:

117452845(inpp5l) 117459683

GACU:

117550918 117561002(inpp5l)

EMAC:

134858611 134873876(inpp5l)

ELY:	117248054 117252094(inpp5l)

EFO:	125890373(inpp5l) 125903575

PLEP:

121944487(inpp5l) 121954486

SLUC:

116039332 116053898(inpp5l)

ECRA:

117944251(inpp5l) 117960395

ESP:	116689723 116705180(inpp5a)

PFLV:

114555936 114572349(inpp5a)

GAT:	120820377 120830395(inpp5l)

PPUG:

119213835 119224577(inpp5l)

AFB:	129092199 129101531(inpp5l)

CLUM:

117736764(inpp5l) 117743862

PSWI:

130197047(inpp5l) 130207478

MSAM:

119892450(inpp5l) 119917210

SCHU:

122876169(inpp5l) 122884277

CUD:	121509864(inpp5l) 121511093

ALAT:

119019322(inpp5l) 119033931

ASTR:

137592381(inpp5l) 137603981

MZE:	101472350(inpp5a) 101485329

ONL:	100697205(inpp5a) 100700932

OAU:	116318505 116335699(inpp5l)

OLA:	101156112(inpp5a) 101171587

OML:	112148030(inpp5l) 112161654

CSAI:

133450335(inpp5l) 133463714

XMA:	102217982 102219699(inpp5a)

XCO:	114137818(inpp5a) 114154692

XHE:	116713048(inpp5a) 116729906

PRET:

103470533(inpp5a)

PFOR:

103146094 103148152(inpp5a)

PLAI:

106948104(inpp5a) 106950397

PMEI:

106915761 106924570

GAF:	122828051(inpp5l) 122842215

PPRL:

129359605 129372098(inpp5l)

CVG:	107082317 107093121(inpp5a)

CTUL:

119783978(inpp5l) 119792739

GMU:	124858855 124878159(inpp5l)

NFU:	107375791(inpp5a) 107393728

KMR:	108236576(inpp5l) 108246561

ALIM:

106520152 106536095

NWH:	119414009(inpp5l)

AOCE:

111582154

MCEP:

125012421(inpp5l) 125018566

CSEM:

103387519(inpp5a) 103397339

POV:	109629471(inpp5a) 109633640

SSEN:

122770122(inpp5l) 122781674

HHIP:

117767497(inpp5l) 117775372

HSP:	118115461(inpp5l) 118119362

PPLT:

128438321(inpp5l) 128453551

SMAU:

118283723 118313571(inpp5l)

LCF:	108878449(inpp5l) 108885135

SDU:	111220660(inpp5a) 111231553

SLAL:

111645064 111669531(inpp5a)

XGL:	120796548 120804982(inpp5l)

HCQ:	109523122(inpp5a) 109525000

SSCV:

125978941 125993934

SBIA:

133499485(inpp5l) 133509797

PEE:	133399735(inpp5l) 133410026

PTAO:

133475535(inpp5l) 133485533

BPEC:

110166333(inpp5a) 110169919

MALB:

109954934 109973245(inpp5a)

BSPL:

114861520(inpp5l) 114870356

SJO:	128364819(inpp5l) 128373359

SASA:

106576776 106585609 106605012

STRU:

115153056 115164518 115193954

OTW:	112248486 112252846 112253060

OMY:	110502317 110525665 110526894

OGO:	124034319 124038148 124041396

ONE:	115111601 115113343 115135265

OKI:	109873678 109888952 109899623

OKE:	118369550 118393208 118401457

SALP:

111951802 111974055 111977840

SNH:	120017547 120020127 120046491

CCLU:

121553490 121569244 121584844

ELS:	105010721(inpp5a) 105014248

SFM:	108925820(inpp5a) 108929551

PKI:	111838230 111858747(inpp5a)

AANG:

118218007 118237538(inpp5l)

LOC:	102688033(inpp5a) 102692930

PSPA:

121302261 121303165 121321733 121325611

ARUT:

117397901 117414695 117417940 117968940

PSEX:

120538897(inpp5l) 120540065

LCM:	102349479(INPP5A) 102366716

CMK:

103180430

RTP:

109917655

CPLA:

122547728 122561115

HOC:	132826461 132836857

LERI:

129703927 129713399

PMRN:

116941390(INPP5A)

LRJ:	133345474(INPP5A)

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG42283(5PtaseI)

DER:

26526597

DSE:

116801694

DSI:	Dsimw501_GD18243(Dsim_GD18243)

DYA:	Dyak_GE27320

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI26124

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006698

CPII:

CNS:

BCOO:

LLL:

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105672434(5PtaseI)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_210258

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

HAW:	110381097 135118352

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106685863(5PtaseI)

NLU:

111054438

HVI:

124359402

PHU:	Phum_PHUM456270

ZNE:

BROR:

IEL:

FCD:

PVM:

PJA:	122243523 122268138

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:	136829477(5PtaseI)

LSM:

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

CSCU:

CVS:	136987232(5PtaseI)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_C09B8.1(ipp-5)

CBR:	CBG_14816(Cbr-ipp-5)

CRQ:	GCK72_024505

NAI:	NECAME_13097

TSP:

Tsp_10192

HRO:	HELRODRAFT_67767

LGI:	LOTGIDRAFT_114260

PVUL:

PCAN:

BGT:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

OVI:	T265_14953

LLON:

NVE:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

HMG:

RES:

TAD:	TRIADDRAFT_31282

AQU:

100631474

ERC:

Ecym_3554

ZRO:	ZYRO0B05060g

NCS:	NCAS_0C03510(NCAS0C03510)

ZMK:	HG535_0C02820

BSC:	COCSADRAFT_38776

BOR:	COCMIDRAFT_27038

AALT:

CC77DRAFT_962065

MBR:	MONBRDRAFT_33207

SRE:	PTSG_05582

EHX:	EMIHUDRAFT_443392

GTT:	GUITHDRAFT_132445

TBR:	Tb11.02.4140

TBG:	TbgDal_XI7070

TCR:	510101.130

LMA:	LMJF_11_1010

LIF:	LINJ_11_1010

LDO:	LDBPK_111010

LMI:	LMXM_11_1010

LMAT:

92516533(LSCM1_06608)

LBZ:	LBRM_11_0810

LPAN:

LPMP_111020

LOI:	92361902(LSCM4_06042)

LEIS:

94181957(GH5_06665)

LENR:

94174093(CUR178_06932)

LEIN:

94190360(JIQ42_06759)

PHET:

94293067(JKF63_07046)

NGR:	NAEGRDRAFT_61180

» show all

Reference

PMID:8198557

Authors

Verjans B, De Smedt F, Lecocq R, Vanweyenberg V, Moreau C, Erneux C

Title

Cloning and expression in Escherichia coli of a dog thyroid cDNA encoding a novel inositol 1,4,5-trisphosphate 5-phosphatase.

Journal

Biochem J 300 ( Pt 1):85-90 (1994)
DOI:10.1042/bj3000085

Sequence

[cfa:403937]

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Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (2793)   
   KEGG GENES (776)   
   KEGG MGENES (241)   
   RefGene (1756)   
   OC (20)   
Literature (1)   
   PubMed (1)   
All databases (2810)   

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