KEGG   ORTHOLOGY: K01253
Entry
K01253                      KO                                     

Name
EPHX1
Definition
microsomal epoxide hydrolase [EC:3.3.2.9]
Pathway
ko00980  Metabolism of xenobiotics by cytochrome P450
ko04976  Bile secretion
ko05204  Chemical carcinogenesis
Disease
H01935  Familial hypercholanemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K01253  EPHX1; microsomal epoxide hydrolase
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K01253  EPHX1; microsomal epoxide hydrolase
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis
    K01253  EPHX1; microsomal epoxide hydrolase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01253  EPHX1; microsomal epoxide hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.9  microsomal epoxide hydrolase
     K01253  EPHX1; microsomal epoxide hydrolase
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S33
   K01253  EPHX1; microsomal epoxide hydrolase
Other DBs
RN: R07013 R07014 R07027 R07071 R07072 R07082 R09410 R09417 R09443
COG: COG0596
GO: 0004301
Genes
HSA: 2052(EPHX1)
PTR: 457777(EPHX1)
PPS: 100995858(EPHX1)
GGO: 101130068(EPHX1)
PON: 100173792(EPHX1) 100437687
NLE: 100592261(EPHX1)
MCC: 700180(EPHX1)
MCF: 101866419(EPHX1)
CSAB: 103230002(EPHX1)
RRO: 104660094(EPHX1)
RBB: 108538734(EPHX1)
CJC: 100409580(EPHX1)
SBQ: 101029266(EPHX1)
MMU: 13849(Ephx1)
MCAL: 110290857(Ephx1)
MPAH: 110321688(Ephx1)
RNO: 25315(Ephx1)
MUN: 110559921(Ephx1)
CGE: 100750792(Ephx1) 100758590
HGL: 101725522(Ephx1)
OCU: 100009104(EPHX1)
TUP: 102495357(EPHX1)
CFA: 480113(EPHX1)
VVP: 112923564(EPHX1)
AML: 100477671(EPHX1)
UMR: 103669061(EPHX1)
UAH: 113262914(EPHX1)
ORO: 101368385(EPHX1)
ELK: 111150921
FCA: 101085519(EPHX1)
PTG: 102949568(EPHX1)
PPAD: 109250808(EPHX1)
AJU: 106968617(EPHX1)
BTA: 535293(EPHX1)
BOM: 102267623(EPHX1)
BIU: 109570425(EPHX1)
BBUB: 102409402(EPHX1)
CHX: 100860945(EPHX1)
OAS: 101111038(EPHX1)
SSC: 397639(EPHX1)
CFR: 102519415(EPHX1)
CDK: 105099693(EPHX1)
BACU: 103003233(EPHX1)
LVE: 103074317(EPHX1)
OOR: 101288139(EPHX1)
DLE: 111177519(EPHX1)
PCAD: 102984566(EPHX1)
ECB: 100054269(EPHX1)
EPZ: 103543505(EPHX1)
EAI: 106844729(EPHX1)
MYB: 102263401(EPHX1)
MYD: 102767193(EPHX1)
MNA: 107543604(EPHX1)
HAI: 109391461(EPHX1)
DRO: 112318922(EPHX1)
PALE: 102883919(EPHX1)
RAY: 107517097(EPHX1)
MJV: 108408993(EPHX1)
LAV: 100673770(EPHX1)
TMU: 101360751
MDO: 100025778(EPHX1)
SHR: 100925093(EPHX1)
PCW: 110205523(EPHX1)
OAA: 100081956(EPHX1)
GGA: 421321(EPHX1) 421447(EPHX1L)
MGP: 100539493 100545721(EPHX1)
CJO: 107311037(EPHX1) 107311272
NMEL: 110395399(EPHX1)
APLA: 101790722 101801005(EPHX1)
ACYG: 106031535(EPHX1)
TGU: 100222959(EPHX1) 100227392
LSR: 110477509(EPHX1)
SCAN: 103819288(EPHX1)
GFR: 102041759(EPHX1) 102042334
FAB: 101806940(EPHX1) 101814529
PHI: 102100615 102109472(EPHX1)
PMAJ: 107201817(EPHX1)
CCAE: 111926266(EPHX1)
CCW: 104684354 104685565(EPHX1)
ETL: 114073697(EPHX1)
FPG: 101912868 101914944(EPHX1)
FCH: 102050687 102059804(EPHX1)
CLV: 102085632(EPHX1) 102092641
EGZ: 104134609(EPHX1)
NNI: 104019274(EPHX1)
ACUN: 113478105(EPHX1)
PADL: 103925015(EPHX1)
AAM: 106482713(EPHX1) 106485556
ASN: 102368835(EPHX1) 102386213
AMJ: 102571832 102577262(EPHX1)
PSS: 102456152 102457257(EPHX1)
CMY: 102934448(EPHX1) 102942209
CPIC: 101936865(EPHX1) 101949762
ACS: 100554472 100555586(ephx1)
PVT: 110075401(EPHX1)
PBI: 103058096(EPHX1)
PMUR: 107289275(EPHX1)
TSR: 106541570 106542798(EPHX1)
PMUA: 114594523 114594618(EPHX1)
GJA: 107119060(EPHX1)
XLA: 108716563 432100(ephx1.L)
XTR: 100158543(ephx1)
NPR: 108787057(EPHX1)
DRE: 394043(ephx1)
SRX: 107732537
SANH: 107690044(ephx1)
CCAR: 109080243
IPU: 108263372(ephx1)
PHYP: 113542048(ephx1)
AMEX: 103040834(ephx1)
EEE: 113587098(ephx1)
TRU: 101066103(ephx1)
LCO: 104918259 104918311(ephx1)
NCC: 104963447(ephx1)
MZE: 101463752 101487605(ephx1)
ONL: 100693015(ephx1)
OLA: 101166982 101172051(ephx1)
XMA: 102229129 102230310(ephx1)
XCO: 114158698(ephx1)
PRET: 103477226
CVG: 107093270(ephx1)
NFU: 107375461
KMR: 108246518(ephx1)
ALIM: 106532950(ephx1)
AOCE: 111583489(ephx1)
CSEM: 103380678(ephx1)
POV: 109632306(ephx1)
LCF: 108901766(ephx1)
SDU: 111239530(ephx1)
SLAL: 111661516(ephx1)
BPEC: 110154206(ephx1)
MALB: 109958771(ephx1)
ELS: 105017773(ephx1)
SFM: 108925178(ephx1)
PKI: 111854029(ephx1)
LCM: 102353239(EPHX1)
CMK: 103181611
RTP: 109925374(ephx1)
CIN: 100176449
SPU: 588166
APLC: 110978249
SKO: 100371948
PVM: 113814676
TUT: 107364002
DPTE: 113797953
CSCU: 111622807
PTEP: 107446491
CEL: CELE_W01A11.1(W01A11.1)
CBR: CBG18950
BMY: Bm1_48070
TSP: Tsp_04403
LAK: 106154062
NVE: 5500949
EPA: 110242247
ADF: 107344265
PDAM: 113677512
SPIS: 111325313
QSU: 112010208
NCR: NCU08783
NTE: NEUTE1DRAFT122640(NEUTE1DRAFT_122640)
MGR: MGG_14882
SSCK: SPSK_07616
MAW: MAC_05449
MAJ: MAA_09463
CMT: CCM_05222
MBE: MBM_02500
ANI: AN3017.2
ANG: ANI_1_312144(An16g02170)
PTE: PTT_15786
CNE: CNN02220
CNB: CNBN2260
TASA: A1Q1_01368
PUB: SAR11_0803(ephX1)
BCL: ABC1387
 » show all
Reference
  Authors
von Dippe P, Zhu QS, Levy D
  Title
Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase.
  Journal
Biochem Biophys Res Commun 309:804-9 (2003)
DOI:10.1016/j.bbrc.2003.08.074
Reference
  Authors
Decker M, Arand M, Cronin A
  Title
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling.
  Journal
Arch Toxicol 83:297-318 (2009)
DOI:10.1007/s00204-009-0416-0

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