KEGG ORTHOLOGY: K01292

ORTHOLOGY: K01292

Entry

K01292                      KO

Symbol

CPN1

Name

carboxypeptidase N catalytic subunit [EC:3.4.17.3]

Disease

H01136

Carboxypeptidase N deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01292  CPN1; carboxypeptidase N catalytic subunit
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.17  Metallocarboxypeptidases
    3.4.17.3  lysine carboxypeptidase
     K01292  CPN1; carboxypeptidase N catalytic subunit
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M14: carboxypeptidase A family
   K01292  CPN1; carboxypeptidase N catalytic subunit

Other DBs

GO:

0004181

Genes

HSA:	1369(CPN1)

PTR:	107966811(CPN1)

PPS:	100994885(CPN1)

GGO:	101136315(CPN1)

PON:	100448102(CPN1)

NLE:	100595544(CPN1)

MCC:	709434(CPN1)

MCF:	102146119(CPN1)

CSAB:

103216380

CATY:

105581828(CPN1)

PANU:

100997838(CPN1)

TGE:	112631730(CPN1)

RRO:	104656557(CPN1)

RBB:	108535064(CPN1)

TFN:	117068618(CPN1)

PTEH:

111538692(CPN1)

CJC:	100412406(CPN1)

SBQ:	101050699(CPN1)

CSYR:

103263188(CPN1)

MMUR:

105873449(CPN1)

OGA:	100950512(CPN1)

MMU:	93721(Cpn1)

MCAL:

110285505(Cpn1)

MPAH:

110330628(Cpn1)

RNO:	365466(Cpn1)

MCOC:

116103884(Cpn1)

MUN:	110552974(Cpn1)

CGE:	100752048(Cpn1)

PLEU:

114706457(Cpn1)

NGI:

103731905

HGL:	101718051(Cpn1)

CPOC:

100725809(Cpn1)

CCAN:

109681489(Cpn1)

DORD:

105986679(Cpn1)

DSP:	122115859(Cpn1)

NCAR:

124985110

OCU:	100344758(CPN1)

TUP:	102499941(CPN1)

CFA:	477795(CPN1)

VVP:	112914786(CPN1)

VLG:	121484114(CPN1)

AML:	100467677(CPN1)

UMR:	103676448(CPN1)

UAH:	113251825(CPN1)

UAR:	123795859(CPN1)

ELK:

111145084

LLV:

125085202

MPUF:

101681991(CPN1)

ORO:	101363324(CPN1)

EJU:	114205443(CPN1)

ZCA:	113923926(CPN1)

MLX:	118024860(CPN1)

FCA:	101090390(CPN1)

PYU:	121037103(CPN1)

PBG:	122493131(CPN1)

PTG:	102973010(CPN1)

PPAD:

109272764(CPN1)

AJU:	106966861(CPN1)

HHV:	120243179(CPN1)

BTA:	536753(CPN1)

BOM:	102283003(CPN1)

BBUB:

102398093(CPN1)

CHX:	102180453(CPN1)

OAS:	101120287(CPN1)

ODA:	120873526(CPN1)

CCAD:

122446057(CPN1)

SSC:	100157984(CPN1)

CFR:	102505284(CPN1)

CBAI:

105081749(CPN1)

CDK:	105084312(CPN1)

VPC:	102535178(CPN1)

BACU:

103018234(CPN1)

LVE:	103083659(CPN1)

OOR:	101280134(CPN1)

DLE:	111172400(CPN1)

PCAD:

102983536(CPN1)

PSIU:

116741651(CPN1)

ECB:	100070412(CPN1)

EPZ:	103542363(CPN1)

EAI:	106846702(CPN1)

MYB:	102262371(CPN1)

MYD:	102761933(CPN1)

MMYO:

118669863(CPN1)

MLF:	102424554(CPN1)

MNA:	107542522(CPN1)

PKL:	118719387(CPN1)

HAI:	109379588(CPN1)

DRO:	112300350(CPN1)

SHON:

118999526(CPN1)

AJM:	119064550(CPN1)

PDIC:

114497546(CPN1)

PHAS:

123828910(CPN1)

MMF:	118632434(CPN1)

RFQ:	117035766(CPN1)

PALE:

102894046(CPN1)

PGIG:

120609211(CPN1)

PVP:	105304666(CPN1)

RAY:	107499779(CPN1)

MJV:	108409592(CPN1)

TOD:	119233594(CPN1)

SARA:

101538658(CPN1)

LAV:	100664930(CPN1)

TMU:

101340515

DNM:	101432402(CPN1)

MDO:	100020383(CPN1)

GAS:	123238256(CPN1)

SHR:	100924516(CPN1)

PCW:	110215500(CPN1)

OAA:	100087406(CPN1)

GGA:	769143(CPN1)

PCOC:

116231739(CPN1)

MGP:	100545641(CPN1)

CJO:	107316068(CPN1)

NMEL:

110399891(CPN1)

APLA:

101803617(CPN1)

ACYG:

106033451(CPN1)

AFUL:

116491494(CPN1)

TGU:	100231475(CPN1)

LSR:	110473605(CPN1)

SCAN:

103813898(CPN1)

PMOA:

120502201(CPN1)

OTC:	121341719(CPN1)

PRUF:

121350359(CPN1)

GFR:	102043170(CPN1)

FAB:	101818188(CPN1)

PHI:	102110254(CPN1)

PMAJ:

107206689(CPN1)

CCAE:

111930929(CPN1)

CCW:	104697908(CPN1)

ETL:	114071122(CPN1)

ZAB:	102065024(CPN1)

FPG:	101919893(CPN1)

FCH:	102053681(CPN1)

CLV:	102095577(CPN1)

EGZ:	104129072(CPN1)

NNI:	104012843(CPN1)

ACUN:

113481538(CPN1)

TALA:

104357431(CPN1)

PADL:

103916348(CPN1)

ACHC:

115348470(CPN1)

AAM:	106494714(CPN1)

AROW:

112964190(CPN1)

NPD:	112957193(CPN1)

DNE:	112989784(CPN1)

ASN:	102373779(CPN1)

AMJ:	102567467(CPN1)

PSS:	102453241(CPN1)

CMY:	102944605(CPN1)

CPIC:

101948942(CPN1)

TST:	117880168(CPN1)

CABI:

116817684(CPN1)

MRV:	120369441(CPN1)

ACS:	100563397(cpn1)

PVT:	110084028(CPN1)

SUND:

121925729(CPN1)

PBI:	103054238(CPN1)

PMUR:

107287742(CPN1)

TSR:	106537857(CPN1)

PGUT:

117678571(CPN1)

VKO:	123026486(CPN1)

PMUA:

114597618(CPN1)

ZVI:	118094020(CPN1)

GJA:	107121131(CPN1)

STOW:

125438023(CPN1)

XLA:	108696975(cpn1.L) 398791(cpn1.S)

XTR:	550020(cpn1)

NPR:	108789679(CPN1)

RTEM:

120946767(CPN1)

BBUF:

121003335(CPN1)

BGAR:

122941567(CPN1)

DRE:	337172(cpn1)

SRX:	107722209 107755523

SANH:

107684044 107702463

SGH:	107566747 107581572(cpn1)

CCAR:

109094710 109100080(cpn1)

CAUA:

113069504 113073777 113111602

PPRM:

120474619(cpn1)

MAMB:

125255437(cpn1)

IPU:	108274305(cpn1)

PHYP:

113527392(cpn1)

SMEO:

124389254(cpn1)

TFD:	113639001(cpn1)

AMEX:

103037340(cpn1)

EEE:	113587528(cpn1)

TRU:	101063492(cpn1)

LCO:	104927896(cpn1)

NCC:	104953335(cpn1)

CGOB:

115024261(cpn1)

ELY:	117247647(cpn1)

PLEP:

121959210(cpn1)

SLUC:

116061352(cpn1)

ECRA:

117936820(cpn1)

PFLV:

114548707(cpn1)

GAT:	120818892(cpn1)

PPUG:

119213106(cpn1)

MSAM:

119916412(cpn1)

CUD:	121528292(cpn1)

ALAT:

119009416(cpn1)

MZE:	101471524(cpn1)

ONL:	100709588(cpn1)

OAU:	116329798(cpn1)

OLA:	101156125(cpn1)

OML:	112154450(cpn1)

XMA:	102227125(cpn1)

XCO:	114151892(cpn1)

XHE:	116726731(cpn1)

PRET:

103481278(cpn1)

PFOR:

103153384(cpn1)

PLAI:

106948317(cpn1)

PMEI:

106907600(cpn1)

GAF:	122823006(cpn1)

CVG:	107094718(cpn1)

CTUL:

119792205

GMU:	124875638(cpn1)

NFU:	107387875(cpn1)

KMR:	108248818(cpn1)

ALIM:

106536196(cpn1)

NWH:	119423498 119429703

AOCE:

111567296(cpn1)

CSEM:

103381454(cpn1)

POV:	109627019(cpn1)

SSEN:

122759021(cpn1)

HHIP:

117752373(cpn1)

LCF:	108898746(cpn1)

SDU:	111220291(cpn1)

SLAL:

111657127(cpn1)

XGL:	120794083(cpn1)

HCQ:	109523878(cpn1)

BPEC:

110154274(cpn1)

MALB:

109963082(cpn1)

BSPL:

114846334(cpn1)

SASA:

100196707(cpn1)

OTW:	121840653(cpn1)

OMY:	110491814(cpn1)

OGO:	124020313(cpn1)

ONE:	115106756(cpn1)

SALP:

111977708

SNH:	120046428(cpn1)

ELS:	105026237(cpn1)

SFM:	108940406(cpn1)

PKI:	111836044(cpn1)

AANG:

118221373(cpn1)

LOC:	102688364(cpn1)

PSPA:

121322021 121325968

ARUT:

117415124 117417952

LCM:	102367336(CPN1)

RTP:	109924839(cpn1)

BFO:	118414428 118419334

BBEL:

109466903 109478523 109484003

FOC:

EAF:

VDE:

VJA:

SMM:	Smp_142190

» show all

Reference

PMID:3408501

Authors

Skidgel RA, Bennett CD, Schilling JW, Tan FL, Weerasinghe DK, Erdos EG

Title

Amino acid sequence of the N-terminus and selected tryptic peptides of the active subunit of human plasma carboxypeptidase N: comparison with other carboxypeptidases.

Journal

Biochem Biophys Res Commun 154:1323-9 (1988)
DOI:10.1016/0006-291X(88)90284-7

Reference

PMID:14687935

Authors

Matthews KW, Mueller-Ortiz SL, Wetsel RA

Title

Carboxypeptidase N: a pleiotropic regulator of inflammation.

Journal

Mol Immunol 40:785-93 (2004)
DOI:10.1016/j.molimm.2003.10.002

Sequence

[hsa:1369]

All links

Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (623)   
   KEGG GENES (265)   
   KEGG MGENES (139)   
   RefGene (215)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (631)   

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