KEGG   ORTHOLOGY: K01343Help
Entry
K01343                      KO                                     

Name
PLAT
Definition
tissue plasminogen activator [EC:3.4.21.68]
Pathway
ko04371  Apelin signaling pathway
ko04610  Complement and coagulation cascades
ko05202  Transcriptional misregulation in cancer
ko05215  Prostate cancer
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K01343  PLAT; tissue plasminogen activator
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01343  PLAT; tissue plasminogen activator
 09160 Human Diseases
  09161 Cancers: Overview
   05202 Transcriptional misregulation in cancer
    K01343  PLAT; tissue plasminogen activator
  09162 Cancers: Specific types
   05215 Prostate cancer
    K01343  PLAT; tissue plasminogen activator
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K01343  PLAT; tissue plasminogen activator
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases
    K01343  PLAT; tissue plasminogen activator
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K01343  PLAT; tissue plasminogen activator
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.68  t-plasminogen activator
     K01343  PLAT; tissue plasminogen activator
Peptidases [BR:ko01002]
 Serine Peptidases
  Family S1: chymotrypsin family
   K01343  PLAT; tissue plasminogen activator
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Coagulation and fibrinolysis
   K01343  PLAT; tissue plasminogen activator
BRITE hierarchy
Genes
HSA: 5327(PLAT)
PTR: 472748(PLAT)
PPS: 100991098(PLAT)
GGO: 101140046(PLAT)
PON: 100173068(PLAT)
NLE: 100586515(PLAT)
MCC: 704475(PLAT)
MCF: 102145462(PLAT)
CSAB: 103215685(PLAT)
RRO: 104668281(PLAT)
RBB: 108540718(PLAT)
CJC: 100391990(PLAT)
SBQ: 101046492(PLAT)
MMU: 18791(Plat)
RNO: 25692(Plat)
CGE: 100750775(Plat)
NGI: 103749408(Plat)
HGL: 101713266(Plat)
CCAN: 109683543(Plat)
OCU: 100009556(PLAT)
TUP: 102468654(PLAT)
CFA: 482840(PLAT)
AML: 100471928(PLAT)
UMR: 103677060(PLAT)
ORO: 101377749(PLAT)
FCA: 101100299(PLAT)
PTG: 102964598(PLAT)
AJU: 106990011(PLAT)
BTA: 281407(PLAT)
BOM: 102281728(PLAT)
BIU: 109553480(PLAT)
PHD: 102332585(PLAT)
CHX: 102187371(PLAT)
OAS: 101118332(PLAT)
SSC: 397121(PLAT)
CFR: 102507711(PLAT)
CDK: 105086430(PLAT)
BACU: 103012605(PLAT)
LVE: 103088899(PLAT)
OOR: 101285324(PLAT)
ECB: 100050239(PLAT)
EPZ: 103562905(PLAT)
EAI: 106828955(PLAT)
MYB: 102261113(PLAT)
MYD: 102775541(PLAT)
HAI: 109386253(PLAT)
RSS: 109452830(PLAT)
PALE: 102893511(PLAT)
LAV: 100657644(PLAT)
TMU: 101350991
MDO: 100033029(PLAT)
SHR: 100928675(PLAT)
OAA: 100078960(PLAT)
GGA: 426791(PLAT)
MGP: 100542402(PLAT)
CJO: 107323741(PLAT)
APLA: 101790558(PLAT)
ACYG: 106044399(PLAT)
TGU: 100227960(PLAT)
GFR: 102034369(PLAT)
FAB: 101819512(PLAT)
PHI: 102108905(PLAT)
PMAJ: 107213913(PLAT)
CCW: 104694864(PLAT)
FPG: 106112248(PLAT)
FCH: 106631098(PLAT)
CLV: 102093040(PLAT)
EGZ: 104135301(PLAT)
AAM: 106487785(PLAT)
ASN: 102369638(PLAT)
AMJ: 102560959(PLAT)
PSS: 102450593(PLAT)
CMY: 102932303(PLAT)
CPIC: 101945243(PLAT)
ACS: 100568270(plat)
PVT: 110072150(PLAT)
PBI: 103047961(PLAT)
GJA: 107107821(PLAT)
XLA: 399010(plat.L)
XTR: 594962(plat)
NPR: 108791447(PLAT)
DRE: 100320028(plat)
SRX: 107754398
CCAR: 109095149
IPU: 108265556(plat)
AMEX: 103040332(plat)
TRU: 101062205(plat)
LCO: 104921663(plat)
NCC: 104956683(plat)
MZE: 101472111(plat)
OLA: 100049466(plat)
XMA: 102223519(plat)
PRET: 103470022(plat)
NFU: 107394261(plat)
CSEM: 103397764(plat)
LCF: 108881585(plat)
HCQ: 109527086(plat)
BPEC: 110153526(plat)
ELS: 105014297(plat)
SFM: 108920189(plat)
LCM: 102346134(PLAT)
CMK: 103181893(plau)
PMAC: 106708186
BBT: BBta_1433
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3009482
  Authors
Degen SJ, Rajput B, Reich E
  Title
The human tissue plasminogen activator gene.
  Journal
J Biol Chem 261:6972-85 (1986)
  Sequence
[hsa:5327]
Reference
PMID:6337343
  Authors
Pennica D, Holmes WE, Kohr WJ, Harkins RN, Vehar GA, Ward CA, Bennett WF, Yelverton E, Seeburg PH, Heyneker HL, Goeddel DV, Collen D
  Title
Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli.
  Journal
Nature 301:214-21 (1983)
  Sequence
[hsa:5327]

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