KEGG   ORTHOLOGY: K01365Help
Entry
K01365                      KO                                     

Name
CTSL
Definition
cathepsin L [EC:3.4.22.15]
Pathway
ko04140  Autophagy - animal
ko04142  Lysosome
ko04145  Phagosome
ko04210  Apoptosis
ko04612  Antigen processing and presentation
ko05205  Proteoglycans in cancer
ko05323  Rheumatoid arthritis
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K01365  CTSL; cathepsin L
   04142 Lysosome
    K01365  CTSL; cathepsin L
   04140 Autophagy - animal
    K01365  CTSL; cathepsin L
  Cell growth and death
   04210 Apoptosis
    K01365  CTSL; cathepsin L
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    K01365  CTSL; cathepsin L
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K01365  CTSL; cathepsin L
  Immune diseases
   05323 Rheumatoid arthritis
    K01365  CTSL; cathepsin L
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K01365  CTSL; cathepsin L
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.15  cathepsin L
     K01365  CTSL; cathepsin L
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C1: papain family
   K01365  CTSL; cathepsin L
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Papain family
   K01365  CTSL; cathepsin L
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
 Others
  K01365  CTSL; cathepsin L
BRITE hierarchy
Genes
HSA: 1514(CTSL)
PTR: 473484 737449(CTSL)
PPS: 100987260(CTSL)
GGO: 101143280 101143887 101145975(CTSL) 109025034
PON: 100450374(CTSL)
NLE: 100585562 100604414(CTSL)
MCC: 694569(CTSL)
MCF: 102116556(CTSL)
CSAB: 103219700(CTSL) 103247618
RRO: 104659397 104673720(CTSL)
RBB: 108521156(CTSL) 108543421
SBQ: 101030077(CTSL) 101051131
MMU: 13039(Ctsl)
RNO: 25697(Ctsl)
HGL: 101717733
CFA: 102156614
AML: 100484313(CTSV)
BTA: 281108(CTSV) 515200(CTSL)
BOM: 102269419 102285097(CTSV)
BIU: 109563231(CTSL)
CHX: 102185465(CTSL) 102190225(CTSV)
OAS: 101113725(CTSL) 780510(CTSV)
SSC: 100515919(CTSL) 396926(CTSV)
CFR: 102513187(CTSL) 102515353(CTSV)
CDK: 105084679(CTSV) 105084695(CTSL)
BACU: 103003105(CTSL) 103009986
LVE: 103085310(CTSL) 103089492
OOR: 101285992(CTSL) 101289364
ECB: 100061234 100061532(CTSL)
EPZ: 103550840(CTSL) 103563220
EAI: 106828084 106844429(CTSV)
MDO: 100013197
GGA: 420160 427466(CTSV)
MGP: 100546685(CTSL) 100551338
CJO: 107306273(CTSL) 107325555
APLA: 101790109 101803168(CTSL)
ACYG: 106044971 106045392(CTSL)
TGU: 100226165 100232421(CTSL)
GFR: 102031629(CTSL)
FAB: 101814636(CTSL)
PHI: 102099328(CTSL)
PMAJ: 107198348(CTSL)
CCW: 104692009(CTSL)
FPG: 101912292 101914468(CTSL)
FCH: 102046755 102053586(CTSL)
CLV: 102090299(CTSL) 102096675
EGZ: 104124387 104125939(CTSV)
ASN: 102370520 102383850(CTSL)
AMJ: 102560893 102572965(CTSL)
PSS: 102444883(CTSL) 102463027
CPIC: 101930955 101944587(CTSL)
ACS: 100561941(ctsl) 100563896
XLA: 108711337 444163(ctsl.L) 447313(ctsv.L)
XTR: 448179(ctsv)
DRE: 30443(ctslb) 321453(ctsla) 436641(ctsl.1)
LCF: 108875054 108878360(ctsl)
DME: Dmel_CG11459(CG11459) Dmel_CG6692(Cp1)
DSI: Dsimw501_GD10987(Dsim_GD10987) Dsimw501_GD10995(Dsim_GD10995) Dsimw501_GD19566(Dsim_GD19566) Dsimw501_GD19835(Dsim_GD19835) Dsimw501_GD22268(Dsim_GD22268)
AME: 552756
BIM: 100749528
BTER: 100645780
SOC: 105208238
AEC: 105153750
ACEP: 105622747
PBAR: 105424815
HST: 105191348
BMOR: 693031(Bcp)
PMAC: 106716166
PRAP: 110999694
PXY: 105382819
API: 100166071(Ctsl) 100167920
DNX: 107173596
ZNE: 110836278
CEL: CELE_T03E6.7(cpl-1)
CBR: CBG22599(Cbr-cpl-1)
BMY: Bm1_20385
TSP: Tsp_11596
TCC: 18596710
VRA: 106770536
VAR: 108337678
AIP: 110270412
LJA: Lj0g3v0162449.1(Lj0g3v0162449.1) Lj6g3v1995750.1(Lj6g3v1995750.1) Lj6g3v1995800.1(Lj6g3v1995800.1)
LANG: 109360679
PMUM: 103324881
PAVI: 110756418
CPEP: 111788438
RCU: 8283011
JRE: 108990419
CANN: 107871500
NTO: 108943964
OEU: 111370082
DCR: 108225102
SOE: 110776408
DOSA: Os04t0650000-01(Os04g0650000)
OBR: 102709319
ATS: 109743204(LOC109743204) 109748138(LOC109748138) 109762805(LOC109762805) 109762807(LOC109762807)
SITA: 101762122
MUS: 103975024
DCT: 110094569
CRE: CHLREDRAFT_155869(CEP2)
MNG: MNEG_0471
APRO: F751_4068
SMIN: v1.2.002365.t1(symbB.v1.2.002365.t1) v1.2.008591.t1(symbB.v1.2.008591.t1) v1.2.014138.t1(symbB.v1.2.014138.t1) v1.2.015456.t1(symbB.v1.2.015456.t1) v1.2.018196.t1(symbB.v1.2.018196.t1) v1.2.027498.t1(symbB.v1.2.027498.t1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3342889
  Authors
Ritonja A, Popovic T, Kotnik M, Machleidt W, Turk V
  Title
Amino acid sequences of the human kidney cathepsins H and L.
  Journal
FEBS Lett 228:341-5 (1988)
DOI:10.1016/0014-5793(88)80028-0
Reference
PMID:3421948
  Authors
Gal S, Gottesman MM
  Title
Isolation and sequence of a cDNA for human pro-(cathepsin L).
  Journal
Biochem J 253:303-6 (1988)
DOI:10.1042/bj2530303
  Sequence
[hsa:1514]
Reference
PMID:7777858
  Authors
Boujrad N, Ogwuegbu SO, Garnier M, Lee CH, Martin BM, Papadopoulos V
  Title
Identification of a stimulator of steroid hormone synthesis isolated from testis.
  Journal
Science 268:1609-12 (1995)
DOI:10.1126/science.7777858
  Sequence
[rno:25697]

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