KEGG   ORTHOLOGY: K01365Help
Entry
K01365                      KO                                     

Name
CTSL
Definition
cathepsin L [EC:3.4.22.15]
Pathway
ko04140  Autophagy - animal
ko04142  Lysosome
ko04145  Phagosome
ko04210  Apoptosis
ko04612  Antigen processing and presentation
ko05205  Proteoglycans in cancer
ko05323  Rheumatoid arthritis
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K01365  CTSL; cathepsin L
   04142 Lysosome
    K01365  CTSL; cathepsin L
   04140 Autophagy - animal
    K01365  CTSL; cathepsin L
  09143 Cell growth and death
   04210 Apoptosis
    K01365  CTSL; cathepsin L
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K01365  CTSL; cathepsin L
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K01365  CTSL; cathepsin L
  09163 Immune disease
   05323 Rheumatoid arthritis
    K01365  CTSL; cathepsin L
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K01365  CTSL; cathepsin L
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01365  CTSL; cathepsin L
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K01365  CTSL; cathepsin L
  09183 Protein families: signaling and cellular processes
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K01365  CTSL; cathepsin L
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.15  cathepsin L
     K01365  CTSL; cathepsin L
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C1: papain family
   K01365  CTSL; cathepsin L
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Papain family
   K01365  CTSL; cathepsin L
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
 Others
  K01365  CTSL; cathepsin L
BRITE hierarchy
Genes
HSA: 1514(CTSL)
PTR: 473484 737449(CTSL)
PPS: 100987260(CTSL)
GGO: 101143280 101145975 115935969
PON: 100450374(CTSL)
NLE: 100604414(CTSL)
MCC: 694569(CTSL)
MCF: 102116556(CTSL)
CSAB: 103219700(CTSL) 103247618
RRO: 104659397 104673720(CTSL)
RBB: 108521156(CTSL) 108543421
SBQ: 101030077(CTSL) 101051131
MMU: 13039(Ctsl)
RNO: 25697(Ctsl)
HGL: 101717733
CFA: 102156614
AML: 100484313(CTSV)
BTA: 281108(CTSV) 515200(CTSL)
BOM: 102269419 102285097(CTSV)
BIU: 109563231(CTSL)
BBUB: 102394284(CTSV) 102399721(CTSL)
CHX: 102185465(CTSL) 102190225(CTSV)
OAS: 101113725(CTSL) 780510(CTSV)
SSC: 100515919(CTSL) 396926(CTSV)
CFR: 102513187(CTSL) 102515353(CTSV)
CDK: 105084679(CTSV) 105084695(CTSL)
BACU: 103003105(CTSL) 103009986
LVE: 103085310(CTSL) 103089492
OOR: 101285992(CTSL) 101289364
DLE: 111166812 111166814(CTSL)
ECB: 100061234 100061532(CTSL)
EPZ: 103550840(CTSL) 103563220
EAI: 106828084 106844429(CTSV)
MNA: 107543082 107544923(CTSL)
DRO: 112302733(CTSV) 112302874
RAY: 107500189(CTSV) 107502729(CTSL) 107518088
MDO: 100013197
GGA: 420160 427466(CTSV)
MGP: 100546685(CTSL) 100551338
CJO: 107306273(CTSL) 107325555
NMEL: 110388760 110389996(CTSL)
ACYG: 106044971 106045392(CTSL)
TGU: 100226165 100232421(CTSL)
LSR: 110471009(CTSL) 110477893
SCAN: 103822946(CTSL)
GFR: 102031629(CTSL)
FAB: 101814636(CTSL)
PHI: 102099328(CTSL)
PMAJ: 107198348(CTSL)
CCAE: 111941824
CCW: 104692009(CTSL)
ETL: 114056020(CTSL) 114067895
FPG: 101912292 101914468(CTSL)
FCH: 102046755 102053586(CTSL)
CLV: 102090299(CTSL) 102096675
EGZ: 104124387 104125939(CTSV)
NNI: 104011755(CTSL) 104018797
ACUN: 113489368 113490114(CTSL)
PADL: 103920403(CTSL)
ASN: 102370520 102383850(CTSL)
AMJ: 102560893 102572965(CTSL)
PSS: 102444883(CTSL) 102463027
CPIC: 101930955 101944587(CTSL)
ACS: 100561941(ctsl) 100563896
XLA: 108711337 444163(ctsl.L) 447313(ctsv.L)
XTR: 448179(ctsv)
DRE: 30443(ctslb) 321453(ctsla) 436641(ctsl.1)
NCC: 104955950(ctsl) 104962698
LCF: 108875054 108878360(ctsl)
DME: Dmel_CG11459(CG11459) Dmel_CG6692(Cp1)
DSI: Dsimw501_GD10987(Dsim_GD10987) Dsimw501_GD10995(Dsim_GD10995) Dsimw501_GD19566(Dsim_GD19566) Dsimw501_GD19835(Dsim_GD19835) Dsimw501_GD22268(Dsim_GD22268)
AME: 552756
BIM: 100749528
BTER: 100645780
CCAL: 108628348
SOC: 105208238
MPHA: 105838322
AEC: 105153750
ACEP: 105622747
HST: 105191348
DQU: 106746030
OBO: 105277223
PCF: 106792245
MDL: 103568734
BMOR: 693031(Bcp)
BMAN: 114252785
PMAC: 106716166
PRAP: 110999694
HAW: 110372465
PXY: 105382819
API: 100166071(Ctsl) 100167920
DNX: 107173596
ZNE: 110836278
CEL: CELE_T03E6.7(cpl-1)
CBR: CBG22599(Cbr-cpl-1)
BMY: Bm1_20385
TSP: Tsp_11596
ALY: 9322495
CSAT: 104741501
BRP: 103828985
BNA: 106435523
GRA: 105767701
GHI: 107902406
GAB: 108481537
GMX: 100787056
CAM: 101503214
ZJU: 107412408
HBR: 110655419
QSU: 111985704
CANN: 107871500
NTA: 107813475
NTO: 108943964
OEU: 111367124
HAN: 110932503
CCAV: 112505575
DCR: 108225102
NNU: 109115872
PSOM: 113324116
ATS: 109748138(LOC109748138) 109762805(LOC109762805) 109762807(LOC109762807)
ZMA: 100274134(AY110253)
SITA: 101762122
CRE: CHLREDRAFT_155869(CEP2)
MNG: MNEG_0471
SMIN: v1.2.001558.t1(symbB.v1.2.001558.t1) v1.2.008591.t1(symbB.v1.2.008591.t1) v1.2.018196.t1(symbB.v1.2.018196.t1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3342889
  Authors
Ritonja A, Popovic T, Kotnik M, Machleidt W, Turk V
  Title
Amino acid sequences of the human kidney cathepsins H and L.
  Journal
FEBS Lett 228:341-5 (1988)
DOI:10.1016/0014-5793(88)80028-0
Reference
PMID:3421948
  Authors
Gal S, Gottesman MM
  Title
Isolation and sequence of a cDNA for human pro-(cathepsin L).
  Journal
Biochem J 253:303-6 (1988)
DOI:10.1042/bj2530303
  Sequence
[hsa:1514]
Reference
PMID:7777858
  Authors
Boujrad N, Ogwuegbu SO, Garnier M, Lee CH, Martin BM, Papadopoulos V
  Title
Identification of a stimulator of steroid hormone synthesis isolated from testis.
  Journal
Science 268:1609-12 (1995)
DOI:10.1126/science.7777858
  Sequence
[rno:25697]

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