KEGG   ORTHOLOGY: K01388Help
Entry
K01388                      KO                                     

Name
MMP1
Definition
matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
Pathway
ko03320  PPAR signaling pathway
ko04657  IL-17 signaling pathway
ko04926  Relaxin signaling pathway
ko05200  Pathways in cancer
ko05219  Bladder cancer
ko05323  Rheumatoid arthritis
Disease
H00028  Choriocarcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04657 IL-17 signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  Endocrine system
   03320 PPAR signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
   04926 Relaxin signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
   05219 Bladder cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  Immune diseases
   05323 Rheumatoid arthritis
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.7  interstitial collagenase
     K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Peptidases [BR:ko01002]
 Metallo Peptidases
  Family M10
   K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
BRITE hierarchy
Genes
HSA: 4312(MMP1)
PTR: 451510(MMP1)
PPS: 100995251(MMP1)
GGO: 101131051(MMP1)
PON: 100459931(MMP1)
NLE: 100582292(MMP1)
MCC: 703653(MMP1)
MCF: 102142258(MMP1)
CSAB: 103248335(MMP1)
RRO: 104674665(MMP1)
RBB: 108514074(MMP1)
CJC: 100400727(MMP1)
SBQ: 101051246(MMP1)
MMU: 83995(Mmp1a) 83996(Mmp1b)
RNO: 300338(Mmp1b) 300339(Mmp1)
CGE: 100754854(Mmp1)
HGL: 101697620(Mmp1)
CCAN: 109689286(Mmp1)
OCU: 100009110(MMP1)
TUP: 102489479(MMP1) 102490608
CFA: 489428(MMP1)
AML: 100478167
UMR: 103662453(MMP1) 103662455
FCA: 101083957 101084217(MMP1)
PTG: 102951453 102970572(MMP1)
AJU: 106976478 106976487(MMP1)
BTA: 100336562 281308(MMP1)
PHD: 102338917(MMP1)
CHX: 102170620(MMP1)
OAS: 101120355(MMP1) 105602407
SSC: 397320(MMP1)
CFR: 102517049(MMP1)
CDK: 105087169(MMP1)
BACU: 103009752(MMP1)
LVE: 103089047(MMP1)
OOR: 101270980(MMP1)
ECB: 100033896(MMP1)
EPZ: 103552636(MMP1)
EAI: 106843117(MMP1)
MYB: 102253167(MMP1)
MYD: 102770236(MMP1)
HAI: 109376363
RSS: 109439598(MMP1)
PALE: 102893881(MMP1)
LAV: 100656422(MMP1)
TMU: 101341516
MDO: 100012472(MMP1)
SHR: 100915062
OAA: 100078975(MMP1)
GGA: 418982(MMP1)
MGP: 100543241
CJO: 107308399
APLA: 101798298(MMP1)
ACYG: 106034204
TGU: 100218575(MMP1)
GFR: 102045551(MMP1)
FAB: 101811360(MMP1)
PHI: 102110938(MMP1)
PMAJ: 107213683
CCW: 104690063
FPG: 101924590(MMP1)
FCH: 102051111(MMP1)
CLV: 102089808
EGZ: 104128912
AAM: 106495498
AMJ: 102563438(MMP8) 102563684(MMP1) 109281824
PSS: 102448178(MMP1)
CMY: 102939197
ACS: 100552848
PVT: 110089072
GJA: 107119159
XLA: 108708733(mmp1.L) 495287(mmp1.S)
XTR: 594916(mmp1)
DZI: 111292939
EGR: 104420658
MCHA: 111006549
HBR: 110633153
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2167156
  Authors
Templeton NS, Brown PD, Levy AT, Margulies IM, Liotta LA, Stetler-Stevenson WG
  Title
Cloning and characterization of human tumor cell interstitial collagenase.
  Journal
Cancer Res 50:5431-7 (1990)
  Sequence
[hsa:4312]
Reference
  Authors
Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C
  Title
Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.
  Journal
Biochim Biophys Acta 1803:3-19 (2010)
DOI:10.1016/j.bbamcr.2009.07.004
Reference
  Authors
Amalinei C, Caruntu ID, Balan RA
  Title
Biology of metalloproteinases.
  Journal
Rom J Morphol Embryol 48:323-34 (2007)

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