KEGG   ORTHOLOGY: K01389Help
Entry
K01389                      KO                                     

Name
MME, CD10
Definition
neprilysin [EC:3.4.24.11]
Pathway
ko04614  Renin-angiotensin system
ko04640  Hematopoietic cell lineage
ko04974  Protein digestion and absorption
ko05010  Alzheimer disease
Disease
H00063  Spinocerebellar ataxia (SCA)
H00264  Charcot-Marie-Tooth disease (CMT)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K01389  MME, CD10; neprilysin
  09152 Endocrine system
   04614 Renin-angiotensin system
    K01389  MME, CD10; neprilysin
  09154 Digestive system
   04974 Protein digestion and absorption
    K01389  MME, CD10; neprilysin
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K01389  MME, CD10; neprilysin
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases
    K01389  MME, CD10; neprilysin
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K01389  MME, CD10; neprilysin
   04090 CD Molecules
    K01389  CD10, MME; membrane metallo-endopeptidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.11  neprilysin
     K01389  MME, CD10; neprilysin
Peptidases [BR:ko01002]
 Metallo Peptidases
  Family M13: neprilysin family
   K01389  MME, CD10; neprilysin
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K01389  MME, CD10; neprilysin
CD molecules [BR:ko04090]
 Proteins
  K01389  CD10, MME; membrane metallo-endopeptidase
BRITE hierarchy
Genes
HSA: 4311(MME)
PTR: 460792(MME)
PPS: 100985469(MME)
GGO: 101130840(MME)
PON: 100173750(MME)
NLE: 100587997(MME)
MCC: 707667(MME)
MCF: 101925772(MME)
CSAB: 103241443(MME)
RRO: 104668763(MME)
RBB: 108512221(MME)
CJC: 100387438(MME)
SBQ: 101046081(MME)
MMU: 17380(Mme)
RNO: 24590(Mme)
CGE: 100756999(Mme)
NGI: 103726236 103740089(Mme)
HGL: 101715828(Mme)
CCAN: 109693062(Mme)
OCU: 100009251(MME)
TUP: 102478575(MME)
CFA: 477120(MME)
AML: 100474251(MME)
UMR: 103677644(MME)
ORO: 101369234(MME)
FCA: 101087516(MME)
PTG: 102956005(MME)
AJU: 106974867(MME)
BTA: 536741(MME)
BOM: 102276645(MME)
BIU: 109559100(MME)
PHD: 102315885(MME)
CHX: 102184949(MME)
OAS: 101112618(MME)
SSC: 100511536(MME)
CFR: 102510634(MME)
CDK: 105094476(MME)
BACU: 103006902(MME)
LVE: 103088815
OOR: 101279513(MME)
ECB: 100053541(MME)
EPZ: 103551466(MME)
EAI: 106836570(MME)
MYB: 102259140(MME)
MYD: 102757655(MME)
HAI: 109373662(MME)
RSS: 109447536(MME)
PALE: 102892831(MME)
LAV: 100676161(MME)
TMU: 101359371
MDO: 100012497(MME)
SHR: 100920293(MME)
GGA: 425031(MME)
MGP: 100544190(MME)
CJO: 107318419(MME)
APLA: 101804711(MME)
ACYG: 106043555(MME)
TGU: 100224600(MME)
GFR: 102042553(MME)
FAB: 101806893(MME)
PHI: 102110334(MME)
PMAJ: 107208825(MME)
CCW: 104688087(MME)
FPG: 101924415(MME)
FCH: 102059406(MME)
CLV: 102083559(MME)
EGZ: 104122315(MME)
AAM: 106497060(MME)
ASN: 102381364(MME)
AMJ: 102564695(MME)
PSS: 102443820(MME)
CMY: 102942442(MME)
CPIC: 101932856(MME)
ACS: 100558527(mme)
PVT: 110073080(MME)
PBI: 103057528(MME)
GJA: 107114156(MME)
XLA: 108716217(mme.L)
XTR: 101734885(mme)
SRX: 107740972(mme)
SANH: 107670267(mme)
SGH: 107548962
CCAR: 109109415(mme)
IPU: 108264737(mme)
AMEX: 103041883(mme)
TRU: 101067932(mme)
LCO: 104927644(mme)
MZE: 101488070(mme)
OLA: 101170860(mme)
XMA: 102217091(mme) 102217344
PRET: 103474711(mme)
NFU: 107380056(mme)
CSEM: 103378377(mme)
LCF: 108900938(mme)
BPEC: 110163663(mme)
ELS: 105029340(mme)
SFM: 108932122(mme)
LCM: 102360975(MME)
CMK: 103176796(mme)
CEL: CELE_F26G1.6(nep-12)
MMC: Mmcs_0157
MKM: Mkms_0166
MJL: Mjls_0147
MVA: Mvan_0184
MGI: Mflv_0472
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2971756
  Authors
Letarte M, Vera S, Tran R, Addis JB, Onizuka RJ, Quackenbush EJ, Jongeneel CV, McInnes RR
  Title
Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase.
  Journal
J Exp Med 168:1247-53 (1988)
DOI:10.1084/jem.168.4.1247
  Sequence
[hsa:4311]
Reference
  Authors
Miners JS, Baig S, Palmer J, Palmer LE, Kehoe PG, Love S
  Title
Abeta-degrading enzymes in Alzheimer's disease.
  Journal
Brain Pathol 18:240-52 (2008)
DOI:10.1111/j.1750-3639.2008.00132.x
Reference
PMID:7937532
  Authors
Bai JP
  Title
Distribution of brush-border membrane peptidases along the rat intestine.
  Journal
Pharm Res 11:897-900 (1994)

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