KEGG   ORTHOLOGY: K02211Help
Entry
K02211                      KO                                     

Name
CDK9
Definition
cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
Pathway
ko05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancers
   05202 Transcriptional misregulation in cancers
    K02211  CDK9; cyclin-dependent kinase 9
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K02211  CDK9; cyclin-dependent kinase 9
  09182 Protein families: genetic information processing
   03021 Transcription machinery
    K02211  CDK9; cyclin-dependent kinase 9
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     K02211  CDK9; cyclin-dependent kinase 9
    2.7.11.23  [RNA-polymerase]-subunit kinase
     K02211  CDK9; cyclin-dependent kinase 9
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  CDK family
   K02211  CDK9; cyclin-dependent kinase 9
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Super elongation complex (SEC)
     K02211  CDK9; cyclin-dependent kinase 9
    Brd4/P-TEFb complex
     K02211  CDK9; cyclin-dependent kinase 9
    7SK RNP complex
     K02211  CDK9; cyclin-dependent kinase 9
BRITE hierarchy
Other DBs
GO: 0004693 0008353
Genes
HSA: 1025(CDK9)
PTR: 464755(CDK9)
PPS: 100994414(CDK9)
GGO: 101144006(CDK9)
PON: 100438878(CDK9)
NLE: 100585249(CDK9)
MCC: 699840(CDK9)
MCF: 102118388(CDK9)
CSAB: 103239826(CDK9)
RRO: 104665877(CDK9)
RBB: 108542729(CDK9)
CJC: 100387429(CDK9)
SBQ: 101040847(CDK9)
MMU: 107951(Cdk9)
RNO: 362110(Cdk9)
CGE: 100757719(Cdk9)
NGI: 103727310(Cdk9)
HGL: 101722666(Cdk9)
CCAN: 109686784(Cdk9)
TUP: 102480019(CDK9)
CFA: 100855805(CDK9)
AML: 100479557(CDK9)
UMR: 103670450(CDK9)
ORO: 101370744(CDK9)
FCA: 101097767(CDK9)
PTG: 102964867(CDK9)
AJU: 106966318(CDK9)
BTA: 520580(CDK9)
BOM: 102286246(CDK9)
BIU: 109566491(CDK9)
PHD: 102342088(CDK9)
CHX: 102188145(CDK9)
OAS: 101109788(CDK9)
SSC: 100307051(CDK9)
CFR: 102505970(CDK9)
CDK: 105092598(CDK9)
BACU: 103008136(CDK9)
LVE: 103084403(CDK9)
OOR: 101280566(CDK9)
ECB: 100070437(CDK9)
EPZ: 103544991(CDK9)
EAI: 106845462(CDK9)
MYB: 102239055(CDK9)
MYD: 102755858(CDK9)
HAI: 109379833(CDK9)
RSS: 109445874(CDK9)
PALE: 102880359(CDK9)
LAV: 100658383(CDK9)
TMU: 101347668
MDO: 100010850(CDK9)
SHR: 100920167(CDK9)
OAA: 100091817(CDK9)
GGA: 417226(CDK9)
MGP: 100543692(CDK9)
CJO: 107321889(CDK9)
APLA: 101792432(CDK9)
ACYG: 106047273(CDK9)
TGU: 100220490(CDK9)
GFR: 102035968(CDK9)
FAB: 101819061(CDK9)
PHI: 102103623(CDK9)
PMAJ: 107212034(CDK9)
CCW: 104688453(CDK9)
FCH: 102055995(CDK9)
CLV: 102087668(CDK9)
EGZ: 104122317(CDK9)
AAM: 106495278(CDK9)
ASN: 102367963(CDK9)
AMJ: 109280262(CDK9)
PSS: 102458033(CDK9)
CMY: 102933317(CDK9)
CPIC: 101938190(CDK9)
ACS: 100553609(cdk9)
PVT: 110078868(CDK9)
PBI: 103064533(CDK9)
GJA: 107111400(CDK9)
XLA: 380229(cdk9.L) 735101(cdk9.S)
XTR: 448039(cdk9)
NPR: 108799342(CDK9)
DRE: 321602(cdk9)
SANH: 107661602(cdk9)
SGH: 107584653 107585390(cdk9)
IPU: 108279315(CDK9) 108279348
AMEX: 103045072(cdk9)
TRU: 101075585(cdk9)
LCO: 104926256(cdk9)
MZE: 101485106(cdk9)
OLA: 101158180(cdk9)
XMA: 102222646(cdk9)
PRET: 103474093(cdk9)
NFU: 107376847(cdk9)
CSEM: 103389847(cdk9)
LCF: 108900718(cdk9)
HCQ: 109529116(cdk9)
BPEC: 110161743(cdk9)
SASA: 100194736(cdk9)
ELS: 105021773(cdk9)
SFM: 108922634(cdk9)
LCM: 102365476(CDK9)
CMK: 103184677(cdk9)
CIN: 100181821
SPU: 593706
APLC: 110983842
DME: Dmel_CG5179(Cdk9)
DSI: Dsimw501_GD25120(Dsim_GD25120)
MDE: 101892825
AAG: 5577107
AME: 412560(Cdk9)
BIM: 100741830
BTER: 100650770
SOC: 105196103
AEC: 105154396
ACEP: 105623784
PBAR: 105426596
HST: 105185420
CFO: 105253591
LHU: 105678371
PGC: 109858424
TCA: 660097
DPA: 109538884
NVL: 108563764
BMOR: 100379322(Cdk9)
PMAC: 106716399
PRAP: 110993705
DNX: 107162828
ZNE: 110841424
FCD: 110851733
CEL: CELE_H25P06.2(cdk-9)
CBR: CBG15591 CBG20416(Cbr-cdk-9)
BMY: Bm1_20615
CRG: 105331277
OBI: 106871831
EPA: 110246325
ADF: 107339417
HMG: 100215392(cdk9)
VVI: 100253284
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cojocaru M, Bouchard A, Cloutier P, Cooper JJ, Varzavand K, Price DH, Coulombe B
  Title
Transcription factor IIS cooperates with the E3 ligase UBR5 to ubiquitinate the CDK9 subunit of the positive transcription elongation factor B.
  Journal
J Biol Chem 286:5012-22 (2011)
DOI:10.1074/jbc.M110.176628

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