KEGG   ORTHOLOGY: K02271
Entry
K02271                      KO                                     
Symbol
COX7B
Name
cytochrome c oxidase subunit 7b
Pathway
map00190  Oxidative phosphorylation
map01100  Metabolic pathways
map04260  Cardiac muscle contraction
map04714  Thermogenesis
map04932  Non-alcoholic fatty liver disease
map05010  Alzheimer disease
map05012  Parkinson disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05208  Chemical carcinogenesis - reactive oxygen species
map05415  Diabetic cardiomyopathy
Module
M00154  Cytochrome c oxidase
Disease
H01904  Microphthalmia with linear skin defects syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K02271  COX7B; cytochrome c oxidase subunit 7b
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K02271  COX7B; cytochrome c oxidase subunit 7b
  09159 Environmental adaptation
   04714 Thermogenesis
    K02271  COX7B; cytochrome c oxidase subunit 7b
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K02271  COX7B; cytochrome c oxidase subunit 7b
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02271  COX7B; cytochrome c oxidase subunit 7b
   05012 Parkinson disease
    K02271  COX7B; cytochrome c oxidase subunit 7b
   05014 Amyotrophic lateral sclerosis
    K02271  COX7B; cytochrome c oxidase subunit 7b
   05016 Huntington disease
    K02271  COX7B; cytochrome c oxidase subunit 7b
   05020 Prion disease
    K02271  COX7B; cytochrome c oxidase subunit 7b
   05022 Pathways of neurodegeneration - multiple diseases
    K02271  COX7B; cytochrome c oxidase subunit 7b
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K02271  COX7B; cytochrome c oxidase subunit 7b
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K02271  COX7B; cytochrome c oxidase subunit 7b
Other DBs
TC: 3.D.4.11
Genes
HSA: 1349(COX7B) 170712(COX7B2)
PTR: 100615314(COX7B2) 465727(COX7B)
PPS: 100982199 100986707 117976096 117977251
GGO: 101133386 101147253 109024487
PON: 100172849(COX7B) 100451432
NLE: 100591930 100602515 115837591
MCC: 100428437(COX7B2) 706099(COX7B)
MCF: 102123270 102124180 123573477
CSAB: 103232235(COX7B) 103246147(COX7B2)
CATY: 105596112 105596144
CJC: 100390732 100414729(COX7B2)
MMU: 66142(Cox7b) 78174(Cox7b2)
RNO: 100361960(Cox7b2) 303393(Cox7b)
BTA: 100300550(COX7B) 767916(COX7B2)
ECB: 100629332(COX7B2) 100630758
SARA: 101551046
MDO: 100012618
SHR: 100932664
PCW: 110193034
OAA: 100073487
GGA: 771947(COX7B)
PCOC: 116229759
MGP: 723981
CJO: 107312769
NMEL: 110402986
APLA: 101800937
ACYG: 106038569
AFUL: 116494355
TGU: 100219756(COX7B)
LSR: 110467902
SCAN: 103816343
PMOA: 120512634
OTC: 121346536
PRUF: 121362870
GFR: 102043872
FAB: 101811767
PHI: 102105750
PMAJ: 107203841
CCAE: 111929219
CCW: 104691619
ETL: 114063989
ZAB: 102061885
FPG: 101916936
FCH: 102056249
CLV: 102086620
EGZ: 104135698
NNI: 104023195
ACUN: 113479994
TALA: 104361496
PADL: 103920169
ACHC: 115333844
AAM: 106489312
AROW: 112975781
NPD: 112947064
DNE: 112983134
ASN: 102380429
AMJ: 102572384(COX7B)
CPOO: 109313699
GGN: 109300719
PSS: 102452704
CMY: 102946319
CPIC: 101945370
TST: 117883341
CABI: 116817154
MRV: 120371339
SUND: 121936006
PBI: 103063809
PMUR: 107284632
TSR: 106550195
PGUT: 117676026
VKO: 123027280
PMUA: 114589322
ZVI: 118084530
GJA: 107123231
XLA: 108700072(cox7b.S) 447278(cox7b.L)
XTR: 779702(cox7b)
NPR: 108803510
RTEM: 120921904
BBUF: 120977735
BGAR: 122946647
DRE: 563476(cox7b)
PPRM: 120481882
IPU: 108279231
PHYP: 113541649
SMEO: 124398080
TFD: 113662429
AMEX: 103037916
EEE: 113582416
TRU: 101066275
LCO: 104918951
NCC: 104965587
CGOB: 115018636
ELY: 117265289
PLEP: 121952815
SLUC: 116055995
ECRA: 117955343
PFLV: 114566966
GAT: 120821909
PPUG: 119215163
MSAM: 119896019
CUD: 121518941
MZE: 101478334
ONL: 100700847
OAU: 116319037
OLA: 101167565
OML: 112143004
XMA: 102237993
XCO: 114153815
XHE: 116728998
PRET: 103460001
PFOR: 103131184
PLAI: 106941926
PMEI: 106909661
GAF: 122844768
CVG: 107098397
CTUL: 119774428
GMU: 124876036
NFU: 107386688
KMR: 108238043
ALIM: 106532898
NWH: 119420465
AOCE: 111563009
CSEM: 103394928
POV: 109628467
SSEN: 122779259
HHIP: 117774215
LCF: 108893360
SDU: 111234265
SLAL: 111659944
XGL: 120802131
HCQ: 109515543
BPEC: 110156470
MALB: 109959258
SASA: 106568019(COX7B) 106603475(CX7B2)
OTW: 112257912
OMY: 110537530
SFM: 108920031
PKI: 111860818
AANG: 118235258
LOC: 102693553
LCM: 102346907
CMK: 103178978
RTP: 109913255
 » show all
Reference
  Authors
Indrieri A, van Rahden VA, Tiranti V, Morleo M, Iaconis D, Tammaro R, D'Amato I, Conte I, Maystadt I, Demuth S, Zvulunov A, Kutsche K, Zeviani M, Franco B
  Title
Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease.
  Journal
Am J Hum Genet 91:942-9 (2012)
DOI:10.1016/j.ajhg.2012.09.016
Reference
PMID:8382530
  Authors
Sadlock JE, Lightowlers RN, Capaldi RA, Schon EA
  Title
Isolation of a cDNA specifying subunit VIIb of human cytochrome c oxidase.
  Journal
Biochim Biophys Acta 1172:223-5 (1993)
DOI:10.1016/0167-4781(93)90301-S
  Sequence
[hsa:1349]

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