KEGG   ORTHOLOGY: K02326Help
Entry
K02326                      KO                                     

Name
POLE3
Definition
DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
Pathway
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko01100  Metabolic pathways
ko03030  DNA replication
ko03410  Base excision repair
ko03420  Nucleotide excision repair
ko05166  Human T-cell leukemia virus 1 infection
Module
M00263  DNA polymerase epsilon complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K02326  POLE3; DNA polymerase epsilon subunit 3
   00240 Pyrimidine metabolism
    K02326  POLE3; DNA polymerase epsilon subunit 3
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03410 Base excision repair
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03420 Nucleotide excision repair
    K02326  POLE3; DNA polymerase epsilon subunit 3
 09160 Human Diseases
  09167 Infectious diseases
   05166 HTLV-I infection
    K02326  POLE3; DNA polymerase epsilon subunit 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03036 Chromosome and associated proteins
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03400 DNA repair and recombination proteins
    K02326  POLE3; DNA polymerase epsilon subunit 3
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   DNA polymerase
    M00263  DNA polymerase epsilon complex
     K02326  POLE3; DNA polymerase epsilon subunit 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K02326  POLE3; DNA polymerase epsilon subunit 3
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    K02326  POLE3; DNA polymerase epsilon subunit 3
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Chromatin remodeling factors
   CHRAC complex
    K02326  POLE3; DNA polymerase epsilon subunit 3
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      K02326  POLE3; DNA polymerase epsilon subunit 3
BRITE hierarchy
Other DBs
RN: R00375 R00376 R00377 R00378
GO: 0003887
Genes
HSA: 54107(POLE3)
PTR: 741748(POLE3)
PPS: 100971005(POLE3)
GGO: 101130047(POLE3)
PON: 100173898(POLE3)
NLE: 100592542(POLE3)
MCC: 705074(POLE3)
MCF: 101867371(POLE3)
CSAB: 103218985(POLE3)
RRO: 104667876(POLE3)
RBB: 108532151(POLE3)
CJC: 100394191(POLE3)
SBQ: 101053500(POLE3)
MMU: 59001(Pole3)
RNO: 100362333 298098(Pole3)
CGE: 100752018(Pole3)
NGI: 103734520(Pole3)
HGL: 101701491(Pole3)
CCAN: 109684092(Pole3)
OCU: 100355895(POLE3)
TUP: 102483842(POLE3)
CFA: 612550(POLE3)
AML: 100475622(POLE3)
UMR: 103678602(POLE3)
ORO: 101363489(POLE3)
FCA: 101097106(POLE3)
PTG: 102953930(POLE3)
AJU: 106978405(POLE3)
BTA: 510678(POLE3)
BOM: 102277795(POLE3)
BIU: 109563372(POLE3)
PHD: 102333384(POLE3)
CHX: 102173090(POLE3)
OAS: 101106138(POLE3)
SSC: 100517450(POLE3)
CFR: 102515759(POLE3)
CDK: 105103758(POLE3)
BACU: 102998240(POLE3)
LVE: 103082643(POLE3)
OOR: 101288980(POLE3)
ECB: 100050165(POLE3)
EPZ: 103554126(POLE3)
EAI: 106822721(POLE3)
MYB: 102247548(POLE3)
MYD: 102771370(POLE3)
HAI: 109379317(POLE3)
RSS: 109459798(POLE3)
PALE: 102880775(POLE3)
LAV: 104845639(POLE3)
TMU: 101358563
MDO: 100010006(POLE3)
SHR: 100926444(POLE3)
GGA: 417275(POLE3)
MGP: 100549999(POLE3)
CJO: 107321601(POLE3)
APLA: 101797381(POLE3)
ACYG: 106037147(POLE3)
TGU: 100228225(POLE3)
GFR: 102034234(POLE3)
FAB: 101819577(POLE3)
PHI: 102110275(POLE3)
PMAJ: 107211908(POLE3)
CCW: 104688426(POLE3)
FPG: 101914209(POLE3)
FCH: 102046667(POLE3)
EGZ: 104124031(POLE3)
AAM: 106487017(POLE3)
ASN: 102374888(POLE3)
AMJ: 102560165(POLE3)
PSS: 102452418(POLE3)
CMY: 102933347(POLE3)
CPIC: 101934894(POLE3)
PVT: 110087439(POLE3)
PBI: 103067387(POLE3)
GJA: 107120422(POLE3)
XLA: 407748(pole3.L)
XTR: 550018(pole3)
NPR: 108789368(POLE3)
DRE: 393774(pole3)
SRX: 107723347(pole3) 107740970
IPU: 108260448(pole3)
AMEX: 103024896(pole3)
TRU: 101066885(pole3)
LCO: 104937791(pole3) 109137829
MZE: 101472104(pole3)
OLA: 101172142(pole3)
XMA: 102217293(pole3)
PRET: 103460098(pole3) 103460110
NFU: 107381530(pole3)
CSEM: 103378878(pole3)
LCF: 108894290(pole3)
HCQ: 109514459(pole3)
BPEC: 110168044(pole3)
SASA: 100286640(pole3)
ELS: 105021784(pole3)
SFM: 108922695(pole3)
LCM: 102367039(POLE3)
CMK: 103182977(pole3)
CIN: 100169885(cbf-2)
SPU: 580013
APLC: 110976322
SKO: 100378375
DME: Dmel_CG13399(Chrac-14)
DSI: Dsimw501_GD23542(Dsim_GD23542)
DYA: Dyak_GE18772(Dyak_Chrac-14)
MDE: 101888159
AAG: 5572267
AME: 726923(Pole3)
BIM: 100743328
BTER: 100642846
SOC: 105203200
AEC: 105145467
ACEP: 105626047
PBAR: 105427488
HST: 105186177
CFO: 105254275
LHU: 105669228
PGC: 109863227
NVI: 100122550
TCA: 656342
DPA: 109539433
NVL: 108565303
BMOR: 101741556
PMAC: 106708081
PRAP: 110999377
PXY: 105390773
API: 100158862(Pole3)
DNX: 107169626
ZNE: 110828788
FCD: 110848791
CEL: CELE_T26A5.8(T26A5.8)
CBR: CBG19681
TSP: Tsp_09484
CRG: 105331310
MYI: 110451357
OBI: 106872021
LAK: 106180764
SHX: MS3_07383
EPA: 110252401
ADF: 107332979
HMG: 100213235
AQU: 100636363
ATH: AT2G27470(NF-YB11)
CRB: 111831175
BRP: 103829668
THJ: 104826426
CPAP: 110817309
CIT: 102618948
TCC: 18590310
GRA: 105770909
DZI: 111285822
EGR: 104421306
VRA: 106755835
VAR: 108339947
CCAJ: 109798348
CAM: 101491905
LJA: Lj3g3v2994480.1(Lj3g3v2994480.1)
ADU: 107476401
AIP: 107629334
LANG: 109355262
FVE: 101308930
PPER: 109949569
PMUM: 103328056
PAVI: 110769955
MDM: 103453357
PXB: 103934708
ZJU: 107418871
CSV: 101218845
CMO: 103491421
MCHA: 111020575
CMAX: 111490783
CMOS: 111459853
CPEP: 111795460
RCU: 8271925
JCU: 105637416
HBR: 110663141
POP: 7474909
JRE: 108983738
VVI: 100262207
SLY: 101260506
SPEN: 107003250
SOT: 102603585
CANN: 107847624
NSY: 104230566
NTO: 104099883
INI: 109169235
SIND: 105170020
HAN: 110908742
LSV: 111917504
BVG: 104900308
SOE: 110796074
NNU: 104588747
OSA: 4347894
DOSA: Os09t0568200-01(Os09g0568200)
OBR: 102717740
BDI: 104584736
ATS: 109774318(LOC109774318)
SBI: 8062546
ZMA: 100282897(CADR16)
SITA: 101760620
DCT: 110094123
AOF: 109838277
ATR: 18444853
PPP: 112277720
SCE: YDR121W(DPB4)
ERC: Ecym_4295
KMX: KLMA_40151(DPB4)
NCS: NCAS_0B03750(NCAS0B03750)
NDI: NDAI_0J01260(NDAI0J01260)
TPF: TPHA_0A01720(TPHA0A01720)
TBL: TBLA_0H01430(TBLA0H01430)
TDL: TDEL_0F04020(TDEL0F04020)
KAF: KAFR_0B05420(KAFR0B05420)
CAL: CAALFM_C200430CA(DPB4)
CAUR: QG37_00492
SPO: SPBC3D6.09(dpb4)
DDI: DDB_G0272222(ybl1)
NGD: NGA_2104400(POLE3)
SPAR: SPRG_01401
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Shimizu K, Hashimoto K, Kirchner JM, Nakai W, Nishikawa H, Resnick MA, Sugino A
  Title
Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae.
  Journal
J Biol Chem 277:37422-9 (2002)
DOI:10.1074/jbc.M204476200
Reference
  Authors
Spiga MG, D'Urso G
  Title
Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast.
  Journal
Nucleic Acids Res 32:4945-53 (2004)
DOI:10.1093/nar/gkh811
  Sequence

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